A cell preparation of Enterococcus faecalis strain EC-12 stimulates the luminal immunoglobulin A secretion in juvenile calves

Takeshi Tsuruta, Ryo Inoue, Takamitsu Tsukahara, Noritaka Matsubara, Masayuki Hamasaki, Kazunari Ushida

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

The immune system in juvenile calves is immature, so calves are susceptible to several diarrheal and respiratory diseases. Oral administration of lactic acid bacteria (LAB) is known to improve the growth performance and prevent diarrheal and respiratory diseases by stimulating the immune system in juvenile calves. Most of the immunostimulation by LAB is achieved by their cell wall components, and therefore we evaluated the immunostimulation of the cell preparation of Enterococcus faecalis strain EC-12 (EC-12) in juvenile calves in a clinical field. Twenty-nine 1-week old calves were used. Fourteen calves were administered 0.2% (w/w) of an EC-12 preparation that supplemented a milk replacer, and other calves were not supplemented. Feces and serum was collected at day 0, 7 and 49 after the administration to measure the IgA and IgG concentration. The fecal IgA concentration was increased by EC-12 administration at day 49, and the serum IgA concentration was also increased at day 7. These results suggested that oral administration of EC-12 in juvenile calves might have an immunostimulatory effect and provide earlier recovery of IgA levels in mucosal immunity.

Original languageEnglish
Pages (from-to)206-211
Number of pages6
JournalAnimal Science Journal
Volume80
Issue number2
DOIs
Publication statusPublished - Apr 2009
Externally publishedYes

Fingerprint

immunoglobulin A
Enterococcus faecalis
Immunoglobulin A
secretion
calves
Oral Administration
Immunization
Lactic Acid
immunostimulation (physiological)
cells
Bacteria
Mucosal Immunity
Immune System Diseases
Cellular Structures
Serum
Feces
respiratory tract diseases
Cell Wall
oral administration
lactic acid bacteria

Keywords

  • Calf
  • Heat-killed bacteria
  • Immunoglobulin A
  • Immunoglobulin G

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)

Cite this

A cell preparation of Enterococcus faecalis strain EC-12 stimulates the luminal immunoglobulin A secretion in juvenile calves. / Tsuruta, Takeshi; Inoue, Ryo; Tsukahara, Takamitsu; Matsubara, Noritaka; Hamasaki, Masayuki; Ushida, Kazunari.

In: Animal Science Journal, Vol. 80, No. 2, 04.2009, p. 206-211.

Research output: Contribution to journalArticle

Tsuruta, Takeshi ; Inoue, Ryo ; Tsukahara, Takamitsu ; Matsubara, Noritaka ; Hamasaki, Masayuki ; Ushida, Kazunari. / A cell preparation of Enterococcus faecalis strain EC-12 stimulates the luminal immunoglobulin A secretion in juvenile calves. In: Animal Science Journal. 2009 ; Vol. 80, No. 2. pp. 206-211.
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