A case of photoleukomelanoderma due to hydrochlorothiazide contained in Preminent®

Yoshitaka Nakamura, Kei Nemoto, Emi Yokoyama, Masahiko Muto

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

A 75-year-old female had been treated with Nu-Lotan® (losartanpotassium) for hypertension. One month later, her treatment was changed from Nu-Lotan® to Preminent®(losartanpotassium/hydrochlorothiazide) and she developed pruritic edematous erythema on sun-exposed areas. Three month later eruptions appeared and pigmentations and depigmentations developed on the same areas. The minimal erythema dose (MED) of UVA was decreased to 4.4 J/cm2. On withdrawal of the Preminent®, the MED was normalized. We made a diagnosis of photoleukomelanoderma due to hydrochlorothiazide contained in Preminent®.

Original languageEnglish
Pages (from-to)482-485
Number of pages4
JournalNishinihon Journal of Dermatology
Volume73
Issue number5
DOIs
Publication statusPublished - 2011
Externally publishedYes

ASJC Scopus subject areas

  • Dermatology

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