A case of paraneoplastic pemphigus associated with bronchiolitis obliterans-like respiratory symptoms in the absence of a known neoplasm

Toshiko Ishida; Emi Yokoyama; Masahiko Muto; Takao Uchihira; Shunsuke Kamimura; Toshiaki Kamei; Ayako Komai; Takashi Hashimoto

doi:10.2336/nishinihonhifu.66.236

A case of paraneoplastic pemphigus associated with bronchiolitis obliterans-like respiratory symptoms in the absence of a known neoplasm

Toshiko Ishida, Emi Yokoyama, Masahiko Muto, Takao Uchihira, Shunsuke Kamimura, Toshiaki Kamei, Ayako Komai, Takashi Hashimoto

Research output: Contribution to journal › Article › peer-review

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Abstract

We report a case of paraneoplastic pemphigus (PNP). The 62-year-old Japanese female showed clinical, histopathological and immunohistopathological features characteristic of PNP. The results of antigen analysis by both immunoblotting and immunoprecipitation were compatible with those of PNP. The patient exhibited a bronchiolitis obliterans-like respiratory symptoms, and the course was progressive and lethal in spite of extensive therapies, including methylpredonisolone pulse therapy, high-dose cyclosporin and plasmapheresis. Extensive examination and an autopsy did not reveal an apparent tumor. This is a rare case in which no tumor was detected.

Original language	English
Pages (from-to)	236-240
Number of pages	5
Journal	Nishinihon Journal of Dermatology
Volume	66
Issue number	3
DOIs	https://doi.org/10.2336/nishinihonhifu.66.236
Publication status	Published - Jul 14 2004
Externally published	Yes

ASJC Scopus subject areas

Dermatology

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title = "A case of paraneoplastic pemphigus associated with bronchiolitis obliterans-like respiratory symptoms in the absence of a known neoplasm",

abstract = "We report a case of paraneoplastic pemphigus (PNP). The 62-year-old Japanese female showed clinical, histopathological and immunohistopathological features characteristic of PNP. The results of antigen analysis by both immunoblotting and immunoprecipitation were compatible with those of PNP. The patient exhibited a bronchiolitis obliterans-like respiratory symptoms, and the course was progressive and lethal in spite of extensive therapies, including methylpredonisolone pulse therapy, high-dose cyclosporin and plasmapheresis. Extensive examination and an autopsy did not reveal an apparent tumor. This is a rare case in which no tumor was detected.",

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AU - Ishida, Toshiko

AU - Yokoyama, Emi

AU - Muto, Masahiko

AU - Uchihira, Takao

AU - Kamimura, Shunsuke

AU - Kamei, Toshiaki

AU - Komai, Ayako

AU - Hashimoto, Takashi

PY - 2004/7/14

Y1 - 2004/7/14

N2 - We report a case of paraneoplastic pemphigus (PNP). The 62-year-old Japanese female showed clinical, histopathological and immunohistopathological features characteristic of PNP. The results of antigen analysis by both immunoblotting and immunoprecipitation were compatible with those of PNP. The patient exhibited a bronchiolitis obliterans-like respiratory symptoms, and the course was progressive and lethal in spite of extensive therapies, including methylpredonisolone pulse therapy, high-dose cyclosporin and plasmapheresis. Extensive examination and an autopsy did not reveal an apparent tumor. This is a rare case in which no tumor was detected.

AB - We report a case of paraneoplastic pemphigus (PNP). The 62-year-old Japanese female showed clinical, histopathological and immunohistopathological features characteristic of PNP. The results of antigen analysis by both immunoblotting and immunoprecipitation were compatible with those of PNP. The patient exhibited a bronchiolitis obliterans-like respiratory symptoms, and the course was progressive and lethal in spite of extensive therapies, including methylpredonisolone pulse therapy, high-dose cyclosporin and plasmapheresis. Extensive examination and an autopsy did not reveal an apparent tumor. This is a rare case in which no tumor was detected.

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A case of paraneoplastic pemphigus associated with bronchiolitis obliterans-like respiratory symptoms in the absence of a known neoplasm

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