A case of paraneoplastic pemphigus associated with bronchiolitis obliterans-like respiratory symptoms in the absence of a known neoplasm

Toshiko Ishida, Emi Yokoyama, Masahiko Muto, Takao Uchihira, Shunsuke Kamimura, Toshiaki Kamei, Ayako Komai, Takashi Hashimoto

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We report a case of paraneoplastic pemphigus (PNP). The 62-year-old Japanese female showed clinical, histopathological and immunohistopathological features characteristic of PNP. The results of antigen analysis by both immunoblotting and immunoprecipitation were compatible with those of PNP. The patient exhibited a bronchiolitis obliterans-like respiratory symptoms, and the course was progressive and lethal in spite of extensive therapies, including methylpredonisolone pulse therapy, high-dose cyclosporin and plasmapheresis. Extensive examination and an autopsy did not reveal an apparent tumor. This is a rare case in which no tumor was detected.

Original languageEnglish
Pages (from-to)236-240
Number of pages5
JournalNishinihon Journal of Dermatology
Issue number3
Publication statusPublished - Jul 14 2004
Externally publishedYes


ASJC Scopus subject areas

  • Dermatology

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