A case of non-IgA mesangioproliferative glomerulonephritis with huge paramesangial hemispherical deposits

H. Sugimoto, Hirofumi Makino, Jun Wada, Kenichi Shikata, S. Ikeda, Z. Ota

Research output: Contribution to journalArticle

Abstract

A 16-year-old female was admitted to our hospital because of chance proteinuria. On admission, mild proteinuria (0.6g/day) was observed, but microhematuria was not detected during the observation period. All the values of the renal function tests were within the normal range. Her renal biopsy demonstrated a prominent increase in the mesangial area by light microscopy and showed marked paramesangial hemispherical deposits by electron microscopy. Though IgM, IgG, Clq, C3, and fibrinogen were localized in the mesangial region, IgA was not detected by immunofluorescence study. It has been reported that paramesangial hemispherical deposits are strongly indicative of IgA glomerulonephritis. We conclude that this patient is a rare case of non-IgA glomerulonephritis with huge paramesangial hemispherical deposits.

Original languageEnglish
Pages (from-to)1091-1095
Number of pages5
JournalNippon Jinzo Gakkai shi
Volume35
Issue number9
Publication statusPublished - Sep 1993

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Glomerulonephritis
Proteinuria
Immunoglobulin A
Kidney
Fibrinogen
Fluorescent Antibody Technique
Immunoglobulin M
Microscopy
Electron Microscopy
Reference Values
Immunoglobulin G
Observation
Biopsy
Light

ASJC Scopus subject areas

  • Nephrology

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A case of non-IgA mesangioproliferative glomerulonephritis with huge paramesangial hemispherical deposits. / Sugimoto, H.; Makino, Hirofumi; Wada, Jun; Shikata, Kenichi; Ikeda, S.; Ota, Z.

In: Nippon Jinzo Gakkai shi, Vol. 35, No. 9, 09.1993, p. 1091-1095.

Research output: Contribution to journalArticle

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