A case of nephrotic syndrome and renal dysfunction in a pregnant woman with diabetes mellitus

K. Hironaka, H. Makino, I. Kumagai, T. Haramoto, Y. Yamasaki, K. Shikata, M. Takahashi, M. Nishii, Z. Ota

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

A 29-year-old diabetic woman who developed severe anaemia, nephrotic syndrome, and hypertension before the 28th week of gestation, had residual evidence of toxaemia and renal dysfunction more than 1 month following delivery. The histopathological findings of renal biopsy specimens were considered most consistent with toxaemia of pregnancy complicated by diabetic glomerulosclerosis. We consider that rapid acceleration of renal dysfunction may have been induced by : (1) poor control of diabetes before pregnancy; (2) glomerular hyperfiltration of the remnant nephrons throughout pregnancy; (3) hypercoagulopathy associated with pregnancy; (4) appearance of hypertension following these three conditions.

Original languageEnglish
Pages (from-to)307-311
Number of pages5
JournalDiabetic Medicine
Volume9
Issue number3
Publication statusPublished - 1992

Fingerprint

Nephrotic Syndrome
Pregnant Women
Diabetes Mellitus
Kidney
Pregnancy
Hypertension
Toxemia
Nephrons
Diabetic Nephropathies
Pre-Eclampsia
Anemia
Biopsy

Keywords

  • Diabetic glomerulosclerosis
  • Glomerular hyperfiltration
  • Hypercoagulopathy
  • Toxaemia of pregnancy

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism
  • Internal Medicine

Cite this

A case of nephrotic syndrome and renal dysfunction in a pregnant woman with diabetes mellitus. / Hironaka, K.; Makino, H.; Kumagai, I.; Haramoto, T.; Yamasaki, Y.; Shikata, K.; Takahashi, M.; Nishii, M.; Ota, Z.

In: Diabetic Medicine, Vol. 9, No. 3, 1992, p. 307-311.

Research output: Contribution to journalArticle

Hironaka, K, Makino, H, Kumagai, I, Haramoto, T, Yamasaki, Y, Shikata, K, Takahashi, M, Nishii, M & Ota, Z 1992, 'A case of nephrotic syndrome and renal dysfunction in a pregnant woman with diabetes mellitus', Diabetic Medicine, vol. 9, no. 3, pp. 307-311.
Hironaka, K. ; Makino, H. ; Kumagai, I. ; Haramoto, T. ; Yamasaki, Y. ; Shikata, K. ; Takahashi, M. ; Nishii, M. ; Ota, Z. / A case of nephrotic syndrome and renal dysfunction in a pregnant woman with diabetes mellitus. In: Diabetic Medicine. 1992 ; Vol. 9, No. 3. pp. 307-311.
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