A case of multiple retroperitoneal ganglioneuromas

Takao Hiraki, H. Mimura, Hideo Gobara, T. Mukai, S. Hase, H. Fujiwara, Susumu Kanazawa, Hiroyuki Yanai

Research output: Contribution to journalArticle

Abstract

We report a case of a 31-year-old man with multiple ganglioneuromas in the retroperitoneum. Unenhanced abdominal CT images showed a large tumor with punctate calcification and a small tumor in the right retroperitoneum, both of which had homogeneous low attenuation. Dynamic CT images showed that both had minimal enhancement at the early phase. MRI images demonstrated the large one with heterogenous high signal intensity on T2-weighted images and inhomogenous gradual enhancement on dynamic images and the small one with homogenous low signal intensity on T2-weighted images and hypervascularity on dynamic images. Histopathological study confirmed that both were compatible with ganglioneuroma, consisting of ganglion cells, Schwann cells, nerve fibers, collagen and myxoid stroma. There was abundant myxoid stroma and less cellular component in the central part of the large one. On the other hand, the small one consisted mainly of cell component and collagen, possessing scarce myxoid stroma.

Original languageEnglish
Pages (from-to)425-429
Number of pages5
JournalJapanese Journal of Clinical Radiology
Volume50
Issue number3
Publication statusPublished - 2005

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Ganglioneuroma
Collagen
Schwann Cells
Cellular Structures
Nerve Fibers
Ganglia
Neoplasms

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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A case of multiple retroperitoneal ganglioneuromas. / Hiraki, Takao; Mimura, H.; Gobara, Hideo; Mukai, T.; Hase, S.; Fujiwara, H.; Kanazawa, Susumu; Yanai, Hiroyuki.

In: Japanese Journal of Clinical Radiology, Vol. 50, No. 3, 2005, p. 425-429.

Research output: Contribution to journalArticle

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AU - Gobara, Hideo

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AU - Hase, S.

AU - Fujiwara, H.

AU - Kanazawa, Susumu

AU - Yanai, Hiroyuki

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AB - We report a case of a 31-year-old man with multiple ganglioneuromas in the retroperitoneum. Unenhanced abdominal CT images showed a large tumor with punctate calcification and a small tumor in the right retroperitoneum, both of which had homogeneous low attenuation. Dynamic CT images showed that both had minimal enhancement at the early phase. MRI images demonstrated the large one with heterogenous high signal intensity on T2-weighted images and inhomogenous gradual enhancement on dynamic images and the small one with homogenous low signal intensity on T2-weighted images and hypervascularity on dynamic images. Histopathological study confirmed that both were compatible with ganglioneuroma, consisting of ganglion cells, Schwann cells, nerve fibers, collagen and myxoid stroma. There was abundant myxoid stroma and less cellular component in the central part of the large one. On the other hand, the small one consisted mainly of cell component and collagen, possessing scarce myxoid stroma.

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