A case of mediastinal lymph node carcinoma of unknown primary site treated with docetaxel and cisplatin with concurrent thoracic radiation therapy

Yutaro Shiota, Shigeo Imai, Naomi Sasaki, Koo Tahara, Bunjiro Noma, Naokatsu Horita, Akihiko Taniguchi, Tetsuya Ono

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Mediastinal lymph node carcinoma of unknown primary site is rare and may have a better prognosis if extensive treatment is performed. Case, A 69-year-old-male presented with a persistent cough. Chest computed tomography (CT) demonstrated a large tumor 9.5 × 8.2 cm, in the mediastinum, compressing the right main bronchus, the right pulmonary artery, and the superior vena cava. Because fiberoptic bronchoscopy was insufficient for diagnosis, mediastinoscopic tumor biopsy under general anesthesia was undertaken. Histological examination revealed adenocarcinoma. Extensive examinations revealed no other neoplastic lesion except in the mediastinum. Mediastinal lymph node carcinoma of unknown primary site was diagnosed. The patient was treated with docetaxel and cisplatin with concurrent thoracic radiation therapy. A month after the start of chemoradiotherapy, the mediastinal tumor regressed markedly. The patient remained free of symptoms without regrowth of the primary site. Exploration of the body showed no further abnormalities 20 months after disease onset.

Original languageEnglish
Pages (from-to)407-411
Number of pages5
JournalActa Medica Okayama
Volume65
Issue number6
Publication statusPublished - Dec 22 2011

Fingerprint

docetaxel
Radiotherapy
Cisplatin
Tumors
Thorax
Lymph Nodes
Mediastinum
Carcinoma
Chemoradiotherapy
Neoplasms
Superior Vena Cava
Biopsy
Bronchoscopy
Bronchi
Cough
General Anesthesia
Pulmonary Artery
Tomography
Adenocarcinoma

Keywords

  • Chemoradiation
  • Mediastinal lymph node
  • Unknown primary site

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

A case of mediastinal lymph node carcinoma of unknown primary site treated with docetaxel and cisplatin with concurrent thoracic radiation therapy. / Shiota, Yutaro; Imai, Shigeo; Sasaki, Naomi; Tahara, Koo; Noma, Bunjiro; Horita, Naokatsu; Taniguchi, Akihiko; Ono, Tetsuya.

In: Acta Medica Okayama, Vol. 65, No. 6, 22.12.2011, p. 407-411.

Research output: Contribution to journalArticle

Shiota, Yutaro ; Imai, Shigeo ; Sasaki, Naomi ; Tahara, Koo ; Noma, Bunjiro ; Horita, Naokatsu ; Taniguchi, Akihiko ; Ono, Tetsuya. / A case of mediastinal lymph node carcinoma of unknown primary site treated with docetaxel and cisplatin with concurrent thoracic radiation therapy. In: Acta Medica Okayama. 2011 ; Vol. 65, No. 6. pp. 407-411.
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