A case of malignant asymptomatic pancreatic endocrinoma with extrapancreatic growth

Toshihiko Waku, Hirokazu Uetsuka, Naoki Watanabe, Takashi Mori, Shigeo Shiiki, Hajime Nakai, Yohjiroh Orita, Izurni Harafuji, Tadashi Yoshino

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

We describe a case of malignant asymptomatic pancreatic endocrinoma with extrapancreatic growth. A 75-year-old man was seen at a nearby hospital because of general fatigue. He was admitted to our department for close examination. Preoperatively, an extraluminal leiomyosarcoma of the remnant stomach was suspected. At laparotomy, malignant lymphoma invading the small part of the pancreatic tail was suspected, and the tumor was extirpated. The histopathological diagnosis was malignant pancreatic endocrinoma with extrapancreatic growth. With immunocytochemical staining, this tumor was positive for only pancreatic polypeptide (PP). This result suggested the possibility of pancreatic polypeptide-producing endocrinoma (PPoma). At 1 year and 8 months after the operation, abdominal CT showed swelling of the para-aortic lymph nodes. PPomas are very rare. Only 55 cases including this case have been reported in the Japanese and foreign literature. An asymptomatic pancreatic endocrinoma with extrapancreatic growth has not been reported in the Japanese literature. The preoperative diagnosis of asymptomatic tumors with extrapancreatic growth is considered to be very difficult.

Original languageEnglish
Pages (from-to)1942-1946
Number of pages5
JournalJapanese Journal of Gastroenterological Surgery
Volume30
Issue number9
Publication statusPublished - 1997

Fingerprint

Pancreatic Polypeptide
Growth
Gastric Stump
Neoplasms
Leiomyosarcoma
General Hospitals
Laparotomy
Fatigue
Lymphoma
Lymph Nodes
Staining and Labeling

Keywords

  • Asymptomatic pancreatic endocrinoma
  • Extrapancreatic growth
  • PPoma

ASJC Scopus subject areas

  • Gastroenterology
  • Surgery

Cite this

Waku, T., Uetsuka, H., Watanabe, N., Mori, T., Shiiki, S., Nakai, H., ... Yoshino, T. (1997). A case of malignant asymptomatic pancreatic endocrinoma with extrapancreatic growth. Japanese Journal of Gastroenterological Surgery, 30(9), 1942-1946.

A case of malignant asymptomatic pancreatic endocrinoma with extrapancreatic growth. / Waku, Toshihiko; Uetsuka, Hirokazu; Watanabe, Naoki; Mori, Takashi; Shiiki, Shigeo; Nakai, Hajime; Orita, Yohjiroh; Harafuji, Izurni; Yoshino, Tadashi.

In: Japanese Journal of Gastroenterological Surgery, Vol. 30, No. 9, 1997, p. 1942-1946.

Research output: Contribution to journalArticle

Waku, T, Uetsuka, H, Watanabe, N, Mori, T, Shiiki, S, Nakai, H, Orita, Y, Harafuji, I & Yoshino, T 1997, 'A case of malignant asymptomatic pancreatic endocrinoma with extrapancreatic growth', Japanese Journal of Gastroenterological Surgery, vol. 30, no. 9, pp. 1942-1946.
Waku T, Uetsuka H, Watanabe N, Mori T, Shiiki S, Nakai H et al. A case of malignant asymptomatic pancreatic endocrinoma with extrapancreatic growth. Japanese Journal of Gastroenterological Surgery. 1997;30(9):1942-1946.
Waku, Toshihiko ; Uetsuka, Hirokazu ; Watanabe, Naoki ; Mori, Takashi ; Shiiki, Shigeo ; Nakai, Hajime ; Orita, Yohjiroh ; Harafuji, Izurni ; Yoshino, Tadashi. / A case of malignant asymptomatic pancreatic endocrinoma with extrapancreatic growth. In: Japanese Journal of Gastroenterological Surgery. 1997 ; Vol. 30, No. 9. pp. 1942-1946.
@article{d9765a1c55ff4caf97fbb3804b7eb370,
title = "A case of malignant asymptomatic pancreatic endocrinoma with extrapancreatic growth",
abstract = "We describe a case of malignant asymptomatic pancreatic endocrinoma with extrapancreatic growth. A 75-year-old man was seen at a nearby hospital because of general fatigue. He was admitted to our department for close examination. Preoperatively, an extraluminal leiomyosarcoma of the remnant stomach was suspected. At laparotomy, malignant lymphoma invading the small part of the pancreatic tail was suspected, and the tumor was extirpated. The histopathological diagnosis was malignant pancreatic endocrinoma with extrapancreatic growth. With immunocytochemical staining, this tumor was positive for only pancreatic polypeptide (PP). This result suggested the possibility of pancreatic polypeptide-producing endocrinoma (PPoma). At 1 year and 8 months after the operation, abdominal CT showed swelling of the para-aortic lymph nodes. PPomas are very rare. Only 55 cases including this case have been reported in the Japanese and foreign literature. An asymptomatic pancreatic endocrinoma with extrapancreatic growth has not been reported in the Japanese literature. The preoperative diagnosis of asymptomatic tumors with extrapancreatic growth is considered to be very difficult.",
keywords = "Asymptomatic pancreatic endocrinoma, Extrapancreatic growth, PPoma",
author = "Toshihiko Waku and Hirokazu Uetsuka and Naoki Watanabe and Takashi Mori and Shigeo Shiiki and Hajime Nakai and Yohjiroh Orita and Izurni Harafuji and Tadashi Yoshino",
year = "1997",
language = "English",
volume = "30",
pages = "1942--1946",
journal = "Japanese Journal of Gastroenterological Surgery",
issn = "0386-9768",
publisher = "Japanese Society of Gastroenterological Surgery",
number = "9",

}

TY - JOUR

T1 - A case of malignant asymptomatic pancreatic endocrinoma with extrapancreatic growth

AU - Waku, Toshihiko

AU - Uetsuka, Hirokazu

AU - Watanabe, Naoki

AU - Mori, Takashi

AU - Shiiki, Shigeo

AU - Nakai, Hajime

AU - Orita, Yohjiroh

AU - Harafuji, Izurni

AU - Yoshino, Tadashi

PY - 1997

Y1 - 1997

N2 - We describe a case of malignant asymptomatic pancreatic endocrinoma with extrapancreatic growth. A 75-year-old man was seen at a nearby hospital because of general fatigue. He was admitted to our department for close examination. Preoperatively, an extraluminal leiomyosarcoma of the remnant stomach was suspected. At laparotomy, malignant lymphoma invading the small part of the pancreatic tail was suspected, and the tumor was extirpated. The histopathological diagnosis was malignant pancreatic endocrinoma with extrapancreatic growth. With immunocytochemical staining, this tumor was positive for only pancreatic polypeptide (PP). This result suggested the possibility of pancreatic polypeptide-producing endocrinoma (PPoma). At 1 year and 8 months after the operation, abdominal CT showed swelling of the para-aortic lymph nodes. PPomas are very rare. Only 55 cases including this case have been reported in the Japanese and foreign literature. An asymptomatic pancreatic endocrinoma with extrapancreatic growth has not been reported in the Japanese literature. The preoperative diagnosis of asymptomatic tumors with extrapancreatic growth is considered to be very difficult.

AB - We describe a case of malignant asymptomatic pancreatic endocrinoma with extrapancreatic growth. A 75-year-old man was seen at a nearby hospital because of general fatigue. He was admitted to our department for close examination. Preoperatively, an extraluminal leiomyosarcoma of the remnant stomach was suspected. At laparotomy, malignant lymphoma invading the small part of the pancreatic tail was suspected, and the tumor was extirpated. The histopathological diagnosis was malignant pancreatic endocrinoma with extrapancreatic growth. With immunocytochemical staining, this tumor was positive for only pancreatic polypeptide (PP). This result suggested the possibility of pancreatic polypeptide-producing endocrinoma (PPoma). At 1 year and 8 months after the operation, abdominal CT showed swelling of the para-aortic lymph nodes. PPomas are very rare. Only 55 cases including this case have been reported in the Japanese and foreign literature. An asymptomatic pancreatic endocrinoma with extrapancreatic growth has not been reported in the Japanese literature. The preoperative diagnosis of asymptomatic tumors with extrapancreatic growth is considered to be very difficult.

KW - Asymptomatic pancreatic endocrinoma

KW - Extrapancreatic growth

KW - PPoma

UR - http://www.scopus.com/inward/record.url?scp=0008545232&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0008545232&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:0008545232

VL - 30

SP - 1942

EP - 1946

JO - Japanese Journal of Gastroenterological Surgery

JF - Japanese Journal of Gastroenterological Surgery

SN - 0386-9768

IS - 9

ER -