A case of invasive fungal sphenoiditis with nasal septal abscess

Seiichiro Makihara, Ayako Takeuchi, Miki Yamamoto, Kazunori Senoo, Seiko Akagi, Aki Fukumoto, Shin Kariya, Mitsuhiro Okano, Kazunori Nishizaki, Munechika Tsumura, Hisashi Ishihara

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Abstract

We report a case of invasive fungal sphenoiditis with nasal septal abscess. We drained the septal abscess and performed endoscopic transnasal sphenoidotomy. The patient suffered from permanent saddle deformity of the nasal dorsum. Bacteriological cultures of the septal abscess fluid revealed Aspergillus flavus. Therapy with voriconazole failed because of resistance of the fungus, however, successful control of the symptoms was finally obtained by therapy with micafungin and itraconazole based on the minimum inhibitory concentration data.

Original languageEnglish
Pages (from-to)213-220
Number of pages8
JournalPractica Oto-Rhino-Laryngologica
Volume106
Issue number3
DOIs
Publication statusPublished - Mar 12 2013

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Keywords

  • Aspergillus flavus
  • Nasal septal abscess
  • Sphenoiditis

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Makihara, S., Takeuchi, A., Yamamoto, M., Senoo, K., Akagi, S., Fukumoto, A., Kariya, S., Okano, M., Nishizaki, K., Tsumura, M., & Ishihara, H. (2013). A case of invasive fungal sphenoiditis with nasal septal abscess. Practica Oto-Rhino-Laryngologica, 106(3), 213-220. https://doi.org/10.5631/jibirin.106.213