A case of intracranial saccular aneurysm after primary varicella zoster virus infection

Masao Kawatani, Akio Nakai, Takashi Okuno, Hirokazu Tsukahara, Yusei Ohshima, Mitsufumi Mayumi

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

We report a case of intracranial saccular aneurysm that developed 3. years after post-varicella ischemic stroke. A 6-year-old girl without apparent immunologic defects presented with right hemiparesis and expressive aphasia 1. month after chickenpox. Her magnetic resonance imaging scans revealed left basal ganglia infarction because of left lenticulostriate artery occlusion. Although her neurologic symptoms improved gradually, segmental irregular narrowing remained in the A1 and M1 segments of the left anterior and middle cerebral arteries, respectively. Three years later, the follow-up magnetic resonance angiography indicated saccular aneurysm in the anterior communicating artery and the anti-VZV IgG antibody index in the cerebrospinal fluid was elevated. Subclinical reactivation of VZV and the segmental vascular narrowing might cause intracranial aneurysm, even in immunocompetent children.

Original languageEnglish
Pages (from-to)80-82
Number of pages3
JournalBrain and Development
Volume34
Issue number1
DOIs
Publication statusPublished - Jan 1 2012
Externally publishedYes

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Keywords

  • Aneurysm
  • Cerebral infarction
  • Post-varicella angiopathy
  • Varicella

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Developmental Neuroscience
  • Clinical Neurology

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