A case of intracranial saccular aneurysm after primary varicella zoster virus infection

Masao Kawatani; Akio Nakai; Takashi Okuno; Hirokazu Tsukahara; Yusei Ohshima; Mitsufumi Mayumi

doi:10.1016/j.braindev.2011.01.009

A case of intracranial saccular aneurysm after primary varicella zoster virus infection

Masao Kawatani, Akio Nakai, Takashi Okuno, Hirokazu Tsukahara, Yusei Ohshima, Mitsufumi Mayumi

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

We report a case of intracranial saccular aneurysm that developed 3. years after post-varicella ischemic stroke. A 6-year-old girl without apparent immunologic defects presented with right hemiparesis and expressive aphasia 1. month after chickenpox. Her magnetic resonance imaging scans revealed left basal ganglia infarction because of left lenticulostriate artery occlusion. Although her neurologic symptoms improved gradually, segmental irregular narrowing remained in the A1 and M1 segments of the left anterior and middle cerebral arteries, respectively. Three years later, the follow-up magnetic resonance angiography indicated saccular aneurysm in the anterior communicating artery and the anti-VZV IgG antibody index in the cerebrospinal fluid was elevated. Subclinical reactivation of VZV and the segmental vascular narrowing might cause intracranial aneurysm, even in immunocompetent children.

Original language	English
Pages (from-to)	80-82
Number of pages	3
Journal	Brain and Development
Volume	34
Issue number	1
DOIs	https://doi.org/10.1016/j.braindev.2011.01.009
Publication status	Published - Jan 2012
Externally published	Yes

Keywords

Aneurysm
Cerebral infarction
Post-varicella angiopathy
Varicella

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Developmental Neuroscience
Clinical Neurology

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abstract = "We report a case of intracranial saccular aneurysm that developed 3. years after post-varicella ischemic stroke. A 6-year-old girl without apparent immunologic defects presented with right hemiparesis and expressive aphasia 1. month after chickenpox. Her magnetic resonance imaging scans revealed left basal ganglia infarction because of left lenticulostriate artery occlusion. Although her neurologic symptoms improved gradually, segmental irregular narrowing remained in the A1 and M1 segments of the left anterior and middle cerebral arteries, respectively. Three years later, the follow-up magnetic resonance angiography indicated saccular aneurysm in the anterior communicating artery and the anti-VZV IgG antibody index in the cerebrospinal fluid was elevated. Subclinical reactivation of VZV and the segmental vascular narrowing might cause intracranial aneurysm, even in immunocompetent children.",

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AU - Kawatani, Masao

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AU - Okuno, Takashi

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AU - Mayumi, Mitsufumi

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