Abstract
We report a case of intracranial saccular aneurysm that developed 3. years after post-varicella ischemic stroke. A 6-year-old girl without apparent immunologic defects presented with right hemiparesis and expressive aphasia 1. month after chickenpox. Her magnetic resonance imaging scans revealed left basal ganglia infarction because of left lenticulostriate artery occlusion. Although her neurologic symptoms improved gradually, segmental irregular narrowing remained in the A1 and M1 segments of the left anterior and middle cerebral arteries, respectively. Three years later, the follow-up magnetic resonance angiography indicated saccular aneurysm in the anterior communicating artery and the anti-VZV IgG antibody index in the cerebrospinal fluid was elevated. Subclinical reactivation of VZV and the segmental vascular narrowing might cause intracranial aneurysm, even in immunocompetent children.
| Original language | English |
|---|---|
| Pages (from-to) | 80-82 |
| Number of pages | 3 |
| Journal | Brain and Development |
| Volume | 34 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Jan 2012 |
| Externally published | Yes |
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Keywords
- Aneurysm
- Cerebral infarction
- Post-varicella angiopathy
- Varicella
ASJC Scopus subject areas
- Clinical Neurology
- Developmental Neuroscience
- Pediatrics, Perinatology, and Child Health
Cite this
A case of intracranial saccular aneurysm after primary varicella zoster virus infection. / Kawatani, Masao; Nakai, Akio; Okuno, Takashi; Tsukahara, Hirokazu; Ohshima, Yusei; Mayumi, Mitsufumi.
In: Brain and Development, Vol. 34, No. 1, 01.2012, p. 80-82.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - A case of intracranial saccular aneurysm after primary varicella zoster virus infection
AU - Kawatani, Masao
AU - Nakai, Akio
AU - Okuno, Takashi
AU - Tsukahara, Hirokazu
AU - Ohshima, Yusei
AU - Mayumi, Mitsufumi
PY - 2012/1
Y1 - 2012/1
N2 - We report a case of intracranial saccular aneurysm that developed 3. years after post-varicella ischemic stroke. A 6-year-old girl without apparent immunologic defects presented with right hemiparesis and expressive aphasia 1. month after chickenpox. Her magnetic resonance imaging scans revealed left basal ganglia infarction because of left lenticulostriate artery occlusion. Although her neurologic symptoms improved gradually, segmental irregular narrowing remained in the A1 and M1 segments of the left anterior and middle cerebral arteries, respectively. Three years later, the follow-up magnetic resonance angiography indicated saccular aneurysm in the anterior communicating artery and the anti-VZV IgG antibody index in the cerebrospinal fluid was elevated. Subclinical reactivation of VZV and the segmental vascular narrowing might cause intracranial aneurysm, even in immunocompetent children.
AB - We report a case of intracranial saccular aneurysm that developed 3. years after post-varicella ischemic stroke. A 6-year-old girl without apparent immunologic defects presented with right hemiparesis and expressive aphasia 1. month after chickenpox. Her magnetic resonance imaging scans revealed left basal ganglia infarction because of left lenticulostriate artery occlusion. Although her neurologic symptoms improved gradually, segmental irregular narrowing remained in the A1 and M1 segments of the left anterior and middle cerebral arteries, respectively. Three years later, the follow-up magnetic resonance angiography indicated saccular aneurysm in the anterior communicating artery and the anti-VZV IgG antibody index in the cerebrospinal fluid was elevated. Subclinical reactivation of VZV and the segmental vascular narrowing might cause intracranial aneurysm, even in immunocompetent children.
KW - Aneurysm
KW - Cerebral infarction
KW - Post-varicella angiopathy
KW - Varicella
UR - http://www.scopus.com/inward/record.url?scp=83955164304&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=83955164304&partnerID=8YFLogxK
U2 - 10.1016/j.braindev.2011.01.009
DO - 10.1016/j.braindev.2011.01.009
M3 - Article
VL - 34
SP - 80
EP - 82
JO - Brain and Development
JF - Brain and Development
SN - 0387-7604
IS - 1
ER -