A case of infectious eccrine hidradenitis

Takashi Oono, Hironori Matsuura, Shi Morizane, Osamu Yamasaki, Keiji Iwatsuki

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)

Abstract

We report a case of "infectious" neutrophilic eccrine hidradenitis who developed papules on the upper arm and trunk. Histological findings revealed vacuolar degeneration and necrosis of epithelial cells in the eccrine sweat ducts and neutrophils that had migrated through ductal epithelium to the lumen. A microabscess was also seen in the eccrine sweat gland coil. Our patient had received no chemotherapy such as cytarabine. Gram-positive cocci were present in the lesional eccrine duct indicating an infective origin of the disease. Human beta defensin-2, one of epithelial antimicrobial peptides, was present in the lesional epidermis and eccrine duct.

Original languageEnglish
Pages (from-to)142-145
Number of pages4
JournalJournal of Dermatology
Volume33
Issue number2
DOIs
Publication statusPublished - Feb 2006

Keywords

  • Defensin
  • Infectious eccrine hidradenitis
  • Innate immunity
  • Neutrophilic
  • Sweat gland

ASJC Scopus subject areas

  • Dermatology

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