Abstract
Immunoglobulin G4 (IgG4)-related disease is an emerging new clinicopathological disorder that is characterized by elevation of serum IgG4 levels and histological findings of IgG4-positive plasmacytic infiltration. IgG4-related disease may appear synchronously or metachronously in a wide variety of organs. The current patient was found to have pericardial effusion and retroperitoneal fibrosis. He was subsequently diagnosed with coronary artery stenosis. 18F-FDG positron emission tomography showed enhanced FDG uptake in lymph nodes as well as pericardial and peri-aortic tissue. Histopathology of the mediastinal lymph node showed the infiltration of numerous IgG4-positive cells, leading to the diagnosis of IgG4-related lymphadenopathy with pericardial and periarterial involvement.
Original language | English |
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Pages (from-to) | 1709-1713 |
Number of pages | 5 |
Journal | Heart and Vessels |
Volume | 31 |
Issue number | 10 |
DOIs | |
Publication status | Published - Oct 1 2016 |
Externally published | Yes |
Keywords
- Cardiovascular system
- IgG4-related disease
- Lymphadenopathy
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine