Abstract
Immunoglobulin G4 (IgG4)-related disease is an emerging new clinicopathological disorder that is characterized by elevation of serum IgG4 levels and histological findings of IgG4-positive plasmacytic infiltration. IgG4-related disease may appear synchronously or metachronously in a wide variety of organs. The current patient was found to have pericardial effusion and retroperitoneal fibrosis. He was subsequently diagnosed with coronary artery stenosis. 18F-FDG positron emission tomography showed enhanced FDG uptake in lymph nodes as well as pericardial and peri-aortic tissue. Histopathology of the mediastinal lymph node showed the infiltration of numerous IgG4-positive cells, leading to the diagnosis of IgG4-related lymphadenopathy with pericardial and periarterial involvement.
| Original language | English |
|---|---|
| Pages (from-to) | 1-5 |
| Number of pages | 5 |
| Journal | Heart and Vessels |
| DOIs | |
| Publication status | Accepted/In press - Jan 21 2016 |
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Keywords
- Cardiovascular system
- IgG4-related disease
- Lymphadenopathy
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
A case of IgG4-related lymphadenopathy, pericarditis, coronary artery periarteritis and luminal stenosis. / Hourai, Ryoto; Miyamura, Masatoshi; Tasaki, Ryunosuke; Iwata, Akiko; Takeda, Yoshihiro; Morita, Hideaki; Hanaoka, Nobuharu; Tanigawa, Jun; Shibata, Kensaku; Takeshita, Atsushi; Kawano, Mitsuhiro; Sato, Yasuharu; Hirose, Yoshinobu; Ishizaka, Nobukazu.
In: Heart and Vessels, 21.01.2016, p. 1-5.Research output: Contribution to journal › Article
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TY - JOUR
T1 - A case of IgG4-related lymphadenopathy, pericarditis, coronary artery periarteritis and luminal stenosis
AU - Hourai, Ryoto
AU - Miyamura, Masatoshi
AU - Tasaki, Ryunosuke
AU - Iwata, Akiko
AU - Takeda, Yoshihiro
AU - Morita, Hideaki
AU - Hanaoka, Nobuharu
AU - Tanigawa, Jun
AU - Shibata, Kensaku
AU - Takeshita, Atsushi
AU - Kawano, Mitsuhiro
AU - Sato, Yasuharu
AU - Hirose, Yoshinobu
AU - Ishizaka, Nobukazu
PY - 2016/1/21
Y1 - 2016/1/21
N2 - Immunoglobulin G4 (IgG4)-related disease is an emerging new clinicopathological disorder that is characterized by elevation of serum IgG4 levels and histological findings of IgG4-positive plasmacytic infiltration. IgG4-related disease may appear synchronously or metachronously in a wide variety of organs. The current patient was found to have pericardial effusion and retroperitoneal fibrosis. He was subsequently diagnosed with coronary artery stenosis. 18F-FDG positron emission tomography showed enhanced FDG uptake in lymph nodes as well as pericardial and peri-aortic tissue. Histopathology of the mediastinal lymph node showed the infiltration of numerous IgG4-positive cells, leading to the diagnosis of IgG4-related lymphadenopathy with pericardial and periarterial involvement.
AB - Immunoglobulin G4 (IgG4)-related disease is an emerging new clinicopathological disorder that is characterized by elevation of serum IgG4 levels and histological findings of IgG4-positive plasmacytic infiltration. IgG4-related disease may appear synchronously or metachronously in a wide variety of organs. The current patient was found to have pericardial effusion and retroperitoneal fibrosis. He was subsequently diagnosed with coronary artery stenosis. 18F-FDG positron emission tomography showed enhanced FDG uptake in lymph nodes as well as pericardial and peri-aortic tissue. Histopathology of the mediastinal lymph node showed the infiltration of numerous IgG4-positive cells, leading to the diagnosis of IgG4-related lymphadenopathy with pericardial and periarterial involvement.
KW - Cardiovascular system
KW - IgG4-related disease
KW - Lymphadenopathy
UR - http://www.scopus.com/inward/record.url?scp=84955302268&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84955302268&partnerID=8YFLogxK
U2 - 10.1007/s00380-016-0794-1
DO - 10.1007/s00380-016-0794-1
M3 - Article
C2 - 26796136
AN - SCOPUS:84955302268
SP - 1
EP - 5
JO - Heart and Vessels
JF - Heart and Vessels
SN - 0910-8327
ER -