A case of IgG4-related lymphadenopathy, pericarditis, coronary artery periarteritis and luminal stenosis

Ryoto Hourai, Masatoshi Miyamura, Ryunosuke Tasaki, Akiko Iwata, Yoshihiro Takeda, Hideaki Morita, Nobuharu Hanaoka, Jun Tanigawa, Kensaku Shibata, Atsushi Takeshita, Mitsuhiro Kawano, Yasuharu Sato, Yoshinobu Hirose, Nobukazu Ishizaka

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Immunoglobulin G4 (IgG4)-related disease is an emerging new clinicopathological disorder that is characterized by elevation of serum IgG4 levels and histological findings of IgG4-positive plasmacytic infiltration. IgG4-related disease may appear synchronously or metachronously in a wide variety of organs. The current patient was found to have pericardial effusion and retroperitoneal fibrosis. He was subsequently diagnosed with coronary artery stenosis. 18F-FDG positron emission tomography showed enhanced FDG uptake in lymph nodes as well as pericardial and peri-aortic tissue. Histopathology of the mediastinal lymph node showed the infiltration of numerous IgG4-positive cells, leading to the diagnosis of IgG4-related lymphadenopathy with pericardial and periarterial involvement.

Original languageEnglish
Pages (from-to)1-5
Number of pages5
JournalHeart and Vessels
DOIs
Publication statusAccepted/In press - Jan 21 2016

Keywords

  • Cardiovascular system
  • IgG4-related disease
  • Lymphadenopathy

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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  • Cite this

    Hourai, R., Miyamura, M., Tasaki, R., Iwata, A., Takeda, Y., Morita, H., Hanaoka, N., Tanigawa, J., Shibata, K., Takeshita, A., Kawano, M., Sato, Y., Hirose, Y., & Ishizaka, N. (Accepted/In press). A case of IgG4-related lymphadenopathy, pericarditis, coronary artery periarteritis and luminal stenosis. Heart and Vessels, 1-5. https://doi.org/10.1007/s00380-016-0794-1