A case of IgG4-related lymphadenopathy, pericarditis, coronary artery periarteritis and luminal stenosis

Ryoto Hourai; Masatoshi Miyamura; Ryunosuke Tasaki; Akiko Iwata; Yoshihiro Takeda; Hideaki Morita; Nobuharu Hanaoka; Jun Tanigawa; Kensaku Shibata; Atsushi Takeshita; Mitsuhiro Kawano; Yasuharu Sato; Yoshinobu Hirose; Nobukazu Ishizaka

doi:10.1007/s00380-016-0794-1

A case of IgG4-related lymphadenopathy, pericarditis, coronary artery periarteritis and luminal stenosis

Ryoto Hourai, Masatoshi Miyamura, Ryunosuke Tasaki, Akiko Iwata, Yoshihiro Takeda, Hideaki Morita, Nobuharu Hanaoka, Jun Tanigawa, Kensaku Shibata, Atsushi Takeshita, Mitsuhiro Kawano, Yasuharu Sato, Yoshinobu Hirose, Nobukazu Ishizaka

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

Immunoglobulin G4 (IgG4)-related disease is an emerging new clinicopathological disorder that is characterized by elevation of serum IgG4 levels and histological findings of IgG4-positive plasmacytic infiltration. IgG4-related disease may appear synchronously or metachronously in a wide variety of organs. The current patient was found to have pericardial effusion and retroperitoneal fibrosis. He was subsequently diagnosed with coronary artery stenosis. ¹⁸F-FDG positron emission tomography showed enhanced FDG uptake in lymph nodes as well as pericardial and peri-aortic tissue. Histopathology of the mediastinal lymph node showed the infiltration of numerous IgG4-positive cells, leading to the diagnosis of IgG4-related lymphadenopathy with pericardial and periarterial involvement.

Original language	English
Pages (from-to)	1709-1713
Number of pages	5
Journal	Heart and Vessels
Volume	31
Issue number	10
DOIs	https://doi.org/10.1007/s00380-016-0794-1
Publication status	Published - Oct 1 2016

Keywords

Cardiovascular system
IgG4-related disease
Lymphadenopathy

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

Access to Document

10.1007/s00380-016-0794-1

Cite this

Hourai, R., Miyamura, M., Tasaki, R., Iwata, A., Takeda, Y., Morita, H., Hanaoka, N., Tanigawa, J., Shibata, K., Takeshita, A., Kawano, M., Sato, Y., Hirose, Y., & Ishizaka, N. (2016). A case of IgG4-related lymphadenopathy, pericarditis, coronary artery periarteritis and luminal stenosis. Heart and Vessels, 31(10), 1709-1713. https://doi.org/10.1007/s00380-016-0794-1

@article{6fd5c9a5163a488d969a276b6443579c,

title = "A case of IgG4-related lymphadenopathy, pericarditis, coronary artery periarteritis and luminal stenosis",

abstract = "Immunoglobulin G4 (IgG4)-related disease is an emerging new clinicopathological disorder that is characterized by elevation of serum IgG4 levels and histological findings of IgG4-positive plasmacytic infiltration. IgG4-related disease may appear synchronously or metachronously in a wide variety of organs. The current patient was found to have pericardial effusion and retroperitoneal fibrosis. He was subsequently diagnosed with coronary artery stenosis. 18F-FDG positron emission tomography showed enhanced FDG uptake in lymph nodes as well as pericardial and peri-aortic tissue. Histopathology of the mediastinal lymph node showed the infiltration of numerous IgG4-positive cells, leading to the diagnosis of IgG4-related lymphadenopathy with pericardial and periarterial involvement.",

keywords = "Cardiovascular system, IgG4-related disease, Lymphadenopathy",

author = "Ryoto Hourai and Masatoshi Miyamura and Ryunosuke Tasaki and Akiko Iwata and Yoshihiro Takeda and Hideaki Morita and Nobuharu Hanaoka and Jun Tanigawa and Kensaku Shibata and Atsushi Takeshita and Mitsuhiro Kawano and Yasuharu Sato and Yoshinobu Hirose and Nobukazu Ishizaka",

note = "Publisher Copyright: {\textcopyright} 2016, Springer Japan.",

year = "2016",

month = oct,

day = "1",

doi = "10.1007/s00380-016-0794-1",

language = "English",

volume = "31",

pages = "1709--1713",

journal = "Heart and Vessels",

issn = "0910-8327",

publisher = "Springer Japan",

number = "10",

}

TY - JOUR

T1 - A case of IgG4-related lymphadenopathy, pericarditis, coronary artery periarteritis and luminal stenosis

AU - Hourai, Ryoto

AU - Miyamura, Masatoshi

AU - Tasaki, Ryunosuke

AU - Iwata, Akiko

AU - Takeda, Yoshihiro

AU - Morita, Hideaki

AU - Hanaoka, Nobuharu

AU - Tanigawa, Jun

AU - Shibata, Kensaku

AU - Takeshita, Atsushi

AU - Kawano, Mitsuhiro

AU - Sato, Yasuharu

AU - Hirose, Yoshinobu

AU - Ishizaka, Nobukazu

PY - 2016/10/1

Y1 - 2016/10/1

N2 - Immunoglobulin G4 (IgG4)-related disease is an emerging new clinicopathological disorder that is characterized by elevation of serum IgG4 levels and histological findings of IgG4-positive plasmacytic infiltration. IgG4-related disease may appear synchronously or metachronously in a wide variety of organs. The current patient was found to have pericardial effusion and retroperitoneal fibrosis. He was subsequently diagnosed with coronary artery stenosis. 18F-FDG positron emission tomography showed enhanced FDG uptake in lymph nodes as well as pericardial and peri-aortic tissue. Histopathology of the mediastinal lymph node showed the infiltration of numerous IgG4-positive cells, leading to the diagnosis of IgG4-related lymphadenopathy with pericardial and periarterial involvement.

AB - Immunoglobulin G4 (IgG4)-related disease is an emerging new clinicopathological disorder that is characterized by elevation of serum IgG4 levels and histological findings of IgG4-positive plasmacytic infiltration. IgG4-related disease may appear synchronously or metachronously in a wide variety of organs. The current patient was found to have pericardial effusion and retroperitoneal fibrosis. He was subsequently diagnosed with coronary artery stenosis. 18F-FDG positron emission tomography showed enhanced FDG uptake in lymph nodes as well as pericardial and peri-aortic tissue. Histopathology of the mediastinal lymph node showed the infiltration of numerous IgG4-positive cells, leading to the diagnosis of IgG4-related lymphadenopathy with pericardial and periarterial involvement.

KW - Cardiovascular system

KW - IgG4-related disease

KW - Lymphadenopathy

UR - http://www.scopus.com/inward/record.url?scp=84955302268&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84955302268&partnerID=8YFLogxK

U2 - 10.1007/s00380-016-0794-1

DO - 10.1007/s00380-016-0794-1

M3 - Article

C2 - 26796136

AN - SCOPUS:84955302268

VL - 31

SP - 1709

EP - 1713

JO - Heart and Vessels

JF - Heart and Vessels

SN - 0910-8327

IS - 10

ER -

A case of IgG4-related lymphadenopathy, pericarditis, coronary artery periarteritis and luminal stenosis

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this