A case of H. pylori and API2-MALT1 gene-negative gastric mucosa-associated lymphoid tissue lymphoma with a carcinoma-like signet-ring cell lymphoepithelial lesion

Tomonori Sumida, Shinji Nagata, Hiroaki Ohgoshi, Yuki Ishida, Takayasu Kuwabara, Takako Tsumura, Keiji Tsuji, Tohru Hidaka, Mayumi Kaneko, Tadashi Yoshino

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Abstract

A 60-year-old woman presented in February 2003 with an ulcer on the lesser curvature of the anglus. The endoscopic biopsy specimens showed epithelial signet-ring cell associated with lymphoid infiltration, suggesting a diagnosis of gastric cancer. Histopathological examination confirmed the diagnosis of low-grade B-cell lymphoma of MALT with epithelial signet-ring cell lymphoepithelial lesion, which was negative for H. pylori and t (11 ; 18) (q21 ; q21) translocation (API2-MALT1 gene). This case was treated with H. pylori eradication and additional radiation therapy, and the tumor was disappeared.

Original languageEnglish
Pages (from-to)1257-1263
Number of pages7
JournalJapanese Journal of Gastroenterology
Volume103
Issue number11
Publication statusPublished - Nov 1 2006

ASJC Scopus subject areas

  • Gastroenterology

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    Sumida, T., Nagata, S., Ohgoshi, H., Ishida, Y., Kuwabara, T., Tsumura, T., Tsuji, K., Hidaka, T., Kaneko, M., & Yoshino, T. (2006). A case of H. pylori and API2-MALT1 gene-negative gastric mucosa-associated lymphoid tissue lymphoma with a carcinoma-like signet-ring cell lymphoepithelial lesion. Japanese Journal of Gastroenterology, 103(11), 1257-1263.