A case of gastric MALT lymphoma with t(11;18) (q21;q21) translocation which relapsed after 8 courses of CHOP therapy and metastasized to submaxillary gland

A 60-year-old woman had been admitted to a previous hospital because of fever of unknown origin and had been diagnosed as gastric malignant lymphoma (type unknown). She had been treated by 8 courses of CHOP. However, she had been transferred to our hospital because of a gastric lesion's relapse, after one year of the chemotherapy. She was diagnosed as gastric MALT lymphoma in our department. We treated her with radiation (total 46.6 Gy). Half a year after the radiation, a metastasized right submaxillary gland was found and it was resected. A chromosomal test revealed t(11;18) (q21;q21) translocation in this case. We gave her an additional course of rituximab therapy (375 mg/m ²/week×4). She has been complete remission to date (over a year). This case was informative about diagnosis, therapy, relapse and chromosomal translocation of MALT lymphoma.