A case of gastric MALT lymphoma with t(11;18) (q21;q21) translocation which relapsed after 8 courses of CHOP therapy and metastasized to submaxillary gland

Hiroshi Tani; Akira Tari; Hideki Asaoku; Kozo Kashiwado; Eiichi Okamoto; Tadashi Yoshino

A case of gastric MALT lymphoma with t(11;18) (q21;q21) translocation which relapsed after 8 courses of CHOP therapy and metastasized to submaxillary gland

Hiroshi Tani, Akira Tari, Hideki Asaoku, Kozo Kashiwado, Eiichi Okamoto, Tadashi Yoshino

Research output: Contribution to journal › Article › peer-review

Abstract

A 60-year-old woman had been admitted to a previous hospital because of fever of unknown origin and had been diagnosed as gastric malignant lymphoma (type unknown). She had been treated by 8 courses of CHOP. However, she had been transferred to our hospital because of a gastric lesion's relapse, after one year of the chemotherapy. She was diagnosed as gastric MALT lymphoma in our department. We treated her with radiation (total 46.6 Gy). Half a year after the radiation, a metastasized right submaxillary gland was found and it was resected. A chromosomal test revealed t(11;18) (q21;q21) translocation in this case. We gave her an additional course of rituximab therapy (375 mg/m ²/week×4). She has been complete remission to date (over a year). This case was informative about diagnosis, therapy, relapse and chromosomal translocation of MALT lymphoma.

Original language	English
Pages (from-to)	2543-2548
Number of pages	6
Journal	GASTROENTEROLOGICAL ENDOSCOPY
Volume	46
Issue number	12
Publication status	Published - Dec 1 2004

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging
Gastroenterology

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A case of gastric MALT lymphoma with t(11;18) (q21;q21) translocation which relapsed after 8 courses of CHOP therapy and metastasized to submaxillary gland. / Tani, Hiroshi; Tari, Akira; Asaoku, Hideki; Kashiwado, Kozo; Okamoto, Eiichi; Yoshino, Tadashi.

In: GASTROENTEROLOGICAL ENDOSCOPY, Vol. 46, No. 12, 01.12.2004, p. 2543-2548.

Research output: Contribution to journal › Article › peer-review

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abstract = "A 60-year-old woman had been admitted to a previous hospital because of fever of unknown origin and had been diagnosed as gastric malignant lymphoma (type unknown). She had been treated by 8 courses of CHOP. However, she had been transferred to our hospital because of a gastric lesion's relapse, after one year of the chemotherapy. She was diagnosed as gastric MALT lymphoma in our department. We treated her with radiation (total 46.6 Gy). Half a year after the radiation, a metastasized right submaxillary gland was found and it was resected. A chromosomal test revealed t(11;18) (q21;q21) translocation in this case. We gave her an additional course of rituximab therapy (375 mg/m 2/week×4). She has been complete remission to date (over a year). This case was informative about diagnosis, therapy, relapse and chromosomal translocation of MALT lymphoma.",

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AU - Okamoto, Eiichi

AU - Yoshino, Tadashi

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