A case of focal xanthogranulomatous pyelonephritis difficult to differentiate from renal cell carcinoma

Motoo Araki, Yasunobu Hashimoto, Masayuki Nanri, Shiro Onituka, Osamu Ryoji, Hayakazu Nakazawa, Hiroshi Toma, Yutaka Yamaguchi

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

A 34-year-old female with left flank pain persisting for 3 months consulted us on 19 Feb, 2001. Ultrasonography (US), computerized tomography (CT), magnetic resonance imaging (MRI) and renal angiography revealed a cystic renal tumor in the upper pole of the left kidney invading the spleen, and paraaortic lymph node swelling. Left radical nephrectomy combined with splenectomy and partial diaphragmectomy was performed under a tentative diagnosis of renal cell carcinoma. However, histopathological findings revealed xanthogranulomatous pyelonephritis (XGP). XGP is a rare, severe, chronic inflammatory disease characterized by accumulation of lipid laden macrophages. XGP is classified as diffuse or focal type. Preoperative diagnosis of focal XGP is difficult because of radiological similarities to renal cell carcinoma. Our case was more difficult to diagnose because she showed few signs of inflammation and had no history of urinary tract infection or stones.

Original languageEnglish
Pages (from-to)621-624
Number of pages4
JournalActa Urologica Japonica
Volume48
Issue number10
Publication statusPublished - Oct 1 2002
Externally publishedYes

Keywords

  • Flank pain
  • Focal type
  • Renal cell carcinoma
  • Xanthogranulomatous pyelonephritis

ASJC Scopus subject areas

  • Urology

Fingerprint Dive into the research topics of 'A case of focal xanthogranulomatous pyelonephritis difficult to differentiate from renal cell carcinoma'. Together they form a unique fingerprint.

  • Cite this

    Araki, M., Hashimoto, Y., Nanri, M., Onituka, S., Ryoji, O., Nakazawa, H., Toma, H., & Yamaguchi, Y. (2002). A case of focal xanthogranulomatous pyelonephritis difficult to differentiate from renal cell carcinoma. Acta Urologica Japonica, 48(10), 621-624.