A case of drug-induced interstitial pneumonitis after chemotherapy with UFT and leucovorin for multiple lung metastases of rectal cancer

Kosei Takagi; Kazuyuki Kawamoto; Hiroyoshi Ikeda; Tadashi Itoh

A case of drug-induced interstitial pneumonitis after chemotherapy with UFT and leucovorin for multiple lung metastases of rectal cancer

Kosei Takagi, Kazuyuki Kawamoto, Hiroyoshi Ikeda, Tadashi Itoh

Research output: Contribution to journal › Article › peer-review

Abstract

The patient was a 70-year-old male who had multiple lung metastases of rectal cancer. He was administered UFT (300 mg/day) and LV (75 mg/day) after Hartmann operation for rectal cancer. He complained of fever and difficulty breathing after 2 courses of these medicines, and was admitted for UFT-and LV-induced interstitial pneumonitis. Treatment with methylprednisolone (30 mg/day) improved his symptoms and revealed radical findings. He was ready for discharge on the 10th day after treatment. Interstitial pneumonitis-induced UFT and LV is rare, but can lead to severe complications, which should be diagnosed and treated by corticosteroid as soon as possible.

Original language	English
Pages (from-to)	1025-1027
Number of pages	3
Journal	Japanese Journal of Cancer and Chemotherapy
Volume	38
Issue number	6
Publication status	Published - Jun 2011
Externally published	Yes

Keywords

Interstitial pneumonitis
Rectal cancer
UFT and LV

ASJC Scopus subject areas

Medicine(all)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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abstract = "The patient was a 70-year-old male who had multiple lung metastases of rectal cancer. He was administered UFT (300 mg/day) and LV (75 mg/day) after Hartmann operation for rectal cancer. He complained of fever and difficulty breathing after 2 courses of these medicines, and was admitted for UFT-and LV-induced interstitial pneumonitis. Treatment with methylprednisolone (30 mg/day) improved his symptoms and revealed radical findings. He was ready for discharge on the 10th day after treatment. Interstitial pneumonitis-induced UFT and LV is rare, but can lead to severe complications, which should be diagnosed and treated by corticosteroid as soon as possible.",

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AU - Takagi, Kosei

AU - Kawamoto, Kazuyuki

AU - Ikeda, Hiroyoshi

AU - Itoh, Tadashi

PY - 2011/6

Y1 - 2011/6

N2 - The patient was a 70-year-old male who had multiple lung metastases of rectal cancer. He was administered UFT (300 mg/day) and LV (75 mg/day) after Hartmann operation for rectal cancer. He complained of fever and difficulty breathing after 2 courses of these medicines, and was admitted for UFT-and LV-induced interstitial pneumonitis. Treatment with methylprednisolone (30 mg/day) improved his symptoms and revealed radical findings. He was ready for discharge on the 10th day after treatment. Interstitial pneumonitis-induced UFT and LV is rare, but can lead to severe complications, which should be diagnosed and treated by corticosteroid as soon as possible.

AB - The patient was a 70-year-old male who had multiple lung metastases of rectal cancer. He was administered UFT (300 mg/day) and LV (75 mg/day) after Hartmann operation for rectal cancer. He complained of fever and difficulty breathing after 2 courses of these medicines, and was admitted for UFT-and LV-induced interstitial pneumonitis. Treatment with methylprednisolone (30 mg/day) improved his symptoms and revealed radical findings. He was ready for discharge on the 10th day after treatment. Interstitial pneumonitis-induced UFT and LV is rare, but can lead to severe complications, which should be diagnosed and treated by corticosteroid as soon as possible.

KW - Interstitial pneumonitis

KW - Rectal cancer

KW - UFT and LV

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A case of drug-induced interstitial pneumonitis after chemotherapy with UFT and leucovorin for multiple lung metastases of rectal cancer

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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