A case of desmoplastic astrocytoma developing in an adult

Kazuhiko Kurozumi, K. Onoda, S. Tsuchimoto, E. Kondo, T. Furuta

Research output: Contribution to journalArticle

Abstract

A rare case of desmoplastic astrocytoma developing in an adult was reported. A 23-year-old man presented with headache and a right homonymous hemianopsia. Computed tomography revealed a solid tumor (3×4×4cm) with a cyst-like portion in the left parietal lobe. Subsequent magnetic resonance imaging more clearly depicted a densely enhancing solid tumor with a suspicious dural attachment along the parieto-occipital convexity. A left parieto-occipital craniotomy was performed under the preoperative diagnosis of meningioma and the tumor was totally resected. Histological examination revealed areas of spindle-shaped tumor cells in a storiform pattern quite compactly arranged in sheets, bundles, and lobules separated by thick connective tissue. The tumor cells were immunoreactive to glial fibrillary acidic protein (GFAP). No ganglion cells were identified among the tumor cells. There were some areas with no demarcation from brain tissue and the tumor appeared to partially invade the brain parenchyma. Some mitotic figures and necrotic areas were also noticed, but no endothelial proliferation was seen. This tumor was diagnosed as a desmoplastic astrocytoma.

Original languageEnglish
Pages (from-to)564-568
Number of pages5
JournalJapanese Journal of Neurosurgery
Volume10
Issue number8
Publication statusPublished - 2001

Fingerprint

Astrocytoma
Neoplasms
Hemianopsia
Parietal Lobe
Craniotomy
Glial Fibrillary Acidic Protein
Meningioma
Brain Neoplasms
Ganglia
Connective Tissue
Headache
Cysts
Tomography
Magnetic Resonance Imaging
Brain

Keywords

  • Desmoplasia
  • Desmoplastic astrocytoma
  • GFAP
  • Meningioma

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Kurozumi, K., Onoda, K., Tsuchimoto, S., Kondo, E., & Furuta, T. (2001). A case of desmoplastic astrocytoma developing in an adult. Japanese Journal of Neurosurgery, 10(8), 564-568.

A case of desmoplastic astrocytoma developing in an adult. / Kurozumi, Kazuhiko; Onoda, K.; Tsuchimoto, S.; Kondo, E.; Furuta, T.

In: Japanese Journal of Neurosurgery, Vol. 10, No. 8, 2001, p. 564-568.

Research output: Contribution to journalArticle

Kurozumi, K, Onoda, K, Tsuchimoto, S, Kondo, E & Furuta, T 2001, 'A case of desmoplastic astrocytoma developing in an adult', Japanese Journal of Neurosurgery, vol. 10, no. 8, pp. 564-568.
Kurozumi K, Onoda K, Tsuchimoto S, Kondo E, Furuta T. A case of desmoplastic astrocytoma developing in an adult. Japanese Journal of Neurosurgery. 2001;10(8):564-568.
Kurozumi, Kazuhiko ; Onoda, K. ; Tsuchimoto, S. ; Kondo, E. ; Furuta, T. / A case of desmoplastic astrocytoma developing in an adult. In: Japanese Journal of Neurosurgery. 2001 ; Vol. 10, No. 8. pp. 564-568.
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