A case of carcinoma showing thymus-like differentiation with a rapidly lethal course

Tomohiro Nogami, Naruto Taira, Shinichi Toyooka, Takehiro Tanaka, Taeko Mizoo, Takayuki Iwamoto, Tadahiko Shien, Junichi Sou, Shinichiro Miyoshi, Hiroyoshi Doihara

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

A 55-year-old woman underwent a total thyroidectomy for carcinoma showing thymus-like differentiation (CASTLE). The patient was referred to our hospital after the tumor was found to have directly invaded the cervical esophagus and the entire circumference of the trachea. A total thyroidectomy was performed, followed by end-to-end anastomosis of the trachea, suprahyoid release and dissection of bilateral pulmonary ligaments. No major complications, including anastomotic dehiscence or stenosis, were observed. The patient experienced some swallowing disturbances and hoarseness during the perioperative period but fully recovered. Radiotherapy to the neck was performed as an adjuvant therapy. Eleven months after surgery, lower back pain and right leg numbness developed and led to gait inability. Multiple lung and bone recurrences were observed, but no local recurrence. Palliative radiotherapy to the bone metastasis was performed. The patient died of pleural metastasis 14 months after the initial diagnosis of CASTLE.

Original languageEnglish
Pages (from-to)840-844
Number of pages5
JournalCase Reports in Oncology
Volume7
Issue number3
DOIs
Publication statusPublished - Apr 12 2014

Fingerprint

Thymus Gland
Thyroidectomy
Trachea
Carcinoma
Radiotherapy
Neoplasm Metastasis
Bone and Bones
Recurrence
Hoarseness
Lung
Perioperative Period
Hypesthesia
Deglutition
Low Back Pain
Gait
Ligaments
Esophagus
Dissection
Leg
Pathologic Constriction

Keywords

  • Carcinoma showing thymus-like differentiation
  • Infiltrating trachea
  • Reconstruction

ASJC Scopus subject areas

  • Oncology

Cite this

A case of carcinoma showing thymus-like differentiation with a rapidly lethal course. / Nogami, Tomohiro; Taira, Naruto; Toyooka, Shinichi; Tanaka, Takehiro; Mizoo, Taeko; Iwamoto, Takayuki; Shien, Tadahiko; Sou, Junichi; Miyoshi, Shinichiro; Doihara, Hiroyoshi.

In: Case Reports in Oncology, Vol. 7, No. 3, 12.04.2014, p. 840-844.

Research output: Contribution to journalArticle

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