A case of breast cancer with multiple organ metastases responding remarkably to combination therapy of CAF (cyclophosphamide, adriamycin and 5-FU), 5'-DFUR and MPA (medroxyprogesterone acetate)

S. Maruyama, T. Okumoto, K. Kawasaki, Hideo Ino, Y. Kanaya, J. Otani, N. Yokoyama, M. Soda

Research output: Contribution to journalArticle


A 52-year-old woman complaining of breast tumor was diagnosed as having advanced breast cancer (T4bN1M1-Stage IV), with metastasis of multiple organs (lung, liver, mediastinal and unilateral axillary lymph nodes) after which she underwent tumorectomy. Postoperative adjuvant therapy was performed using combined chemoendocrine therapy (CAF + 5'-DFUR + MPA). Following the endocrine therapy, the metastatic lesions of the liver and lung had disappeared. The adverse effects were not remarkable. Complete remission was continued for 2 years and 3 months, and the patient enjoyed a favorable quality of life.

Original languageEnglish
Pages (from-to)2235-2238
Number of pages4
JournalGan to kagaku ryoho. Cancer & chemotherapy
Issue number14
Publication statusPublished - Dec 2000
Externally publishedYes


ASJC Scopus subject areas

  • Cancer Research
  • Pharmacology

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