Abstract
The case was a 54-year-old man with type-3 gastric cancer in the cardia accompanied by multiple liver metastasis. He received combination chemotherapy consisting of CPT-11 (60 mg/body, day 1 and 8)+low-dose 5-FU and CDDP (5-FU 500 mg/body/day and CDDP 5 mg/body/day, day 1-5 and 8-12, continuous infusion) every 3 weeks. The initial 2 courses were administered on an inpatient basis,and further courses as an outpatient. After 7 courses of therapy without severe adverse events, not only primary lesion but also hepatic metastasis disappeared. He has been free from disease for 4 months, and chemotherapy was further continued with TS-1 (100 mg/body, day 1-14)+CPT-11 60 mg/body, day 1, 8), every 3 weeks. CPT-11 in combination with low-dose 5-FU+CDDP can be one of the most effective regimens for unresectable advanced gastric cancer.
| Original language | English |
|---|---|
| Pages (from-to) | 1317-1320 |
| Number of pages | 4 |
| Journal | Gan to kagaku ryoho. Cancer & chemotherapy |
| Volume | 33 |
| Issue number | 9 |
| Publication status | Published - Sep 2006 |
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ASJC Scopus subject areas
- Cancer Research
- Pharmacology
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A case of advanced gastric cancer with liver metastasis completely responding to CPT-11+low-dose 5-FU+CDDP chemotherapy. / Kagawa, Shunsuke; Fujiwara, Toshiyoshi; Tokunaga, Naoyuki; Nishizaki, Masahiko; Uno, Futoshi; Teranishi, Fuminori; Gouchi, Akira; Matsuoka, Junji; Tanaka, Noriaki.
In: Gan to kagaku ryoho. Cancer & chemotherapy, Vol. 33, No. 9, 09.2006, p. 1317-1320.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - A case of advanced gastric cancer with liver metastasis completely responding to CPT-11+low-dose 5-FU+CDDP chemotherapy
AU - Kagawa, Shunsuke
AU - Fujiwara, Toshiyoshi
AU - Tokunaga, Naoyuki
AU - Nishizaki, Masahiko
AU - Uno, Futoshi
AU - Teranishi, Fuminori
AU - Gouchi, Akira
AU - Matsuoka, Junji
AU - Tanaka, Noriaki
PY - 2006/9
Y1 - 2006/9
N2 - The case was a 54-year-old man with type-3 gastric cancer in the cardia accompanied by multiple liver metastasis. He received combination chemotherapy consisting of CPT-11 (60 mg/body, day 1 and 8)+low-dose 5-FU and CDDP (5-FU 500 mg/body/day and CDDP 5 mg/body/day, day 1-5 and 8-12, continuous infusion) every 3 weeks. The initial 2 courses were administered on an inpatient basis,and further courses as an outpatient. After 7 courses of therapy without severe adverse events, not only primary lesion but also hepatic metastasis disappeared. He has been free from disease for 4 months, and chemotherapy was further continued with TS-1 (100 mg/body, day 1-14)+CPT-11 60 mg/body, day 1, 8), every 3 weeks. CPT-11 in combination with low-dose 5-FU+CDDP can be one of the most effective regimens for unresectable advanced gastric cancer.
AB - The case was a 54-year-old man with type-3 gastric cancer in the cardia accompanied by multiple liver metastasis. He received combination chemotherapy consisting of CPT-11 (60 mg/body, day 1 and 8)+low-dose 5-FU and CDDP (5-FU 500 mg/body/day and CDDP 5 mg/body/day, day 1-5 and 8-12, continuous infusion) every 3 weeks. The initial 2 courses were administered on an inpatient basis,and further courses as an outpatient. After 7 courses of therapy without severe adverse events, not only primary lesion but also hepatic metastasis disappeared. He has been free from disease for 4 months, and chemotherapy was further continued with TS-1 (100 mg/body, day 1-14)+CPT-11 60 mg/body, day 1, 8), every 3 weeks. CPT-11 in combination with low-dose 5-FU+CDDP can be one of the most effective regimens for unresectable advanced gastric cancer.
UR - http://www.scopus.com/inward/record.url?scp=33749322071&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33749322071&partnerID=8YFLogxK
M3 - Article
C2 - 16969033
AN - SCOPUS:33749322071
VL - 33
SP - 1317
EP - 1320
JO - Japanese Journal of Cancer and Chemotherapy
JF - Japanese Journal of Cancer and Chemotherapy
SN - 0385-0684
IS - 9
ER -