TY - JOUR
T1 - A case of advanced gastric cancer responding to an FAP (5-FU, ADM, platinum compounds) combined chemotherapy
AU - Miyahara, E.
AU - Takiyama, W.
AU - Sakamoto, N.
AU - Azuma, T.
AU - Ohashi, R.
AU - Kirihara, Y.
AU - Doihara, H.
AU - Yokoyama, N.
AU - Tanada, M.
AU - Soga, H.
AU - Kurita, A.
AU - Saeki, H.
AU - Takashima, S.
AU - Mandai, K.
PY - 1993/1/1
Y1 - 1993/1/1
N2 - An experience with an advanced gastric cancer patient with metastases to bilateral breasts, uterus, abdominal lymph nodes, bilateral axillary and supraclavicular lymph nodes, and bone marrow, responded extremely well to an FAP combined chemotherapy as reported here. The patients received four courses of 5-FU (370 mg/m2/day, for five days, continuous infusion), ADM (30 mg/m2 on day 1, i.v.) and CDDP (55 mg/m2 on day 1, i.v.) every 3 weekks in our hospital. This was followed by 7 months of outpatient therapy with 5-FU (550 mg/m2 on day 1, i.v.), ADM (30 mg/m2 on day 1, i.v.) and CBDCA (330 mg/m2 on day 1, i.v.) for every 4 weeks. The complete remission of the primary and metastatic lesions, that was confirmed by the histological examinations, was obtained after 10 months since the initial treatment started. The toxicity was generally moderate, however, the alopecia was severe. The patient has been living for 6 months without any signs of the recurrence after the complete remission obtained.
AB - An experience with an advanced gastric cancer patient with metastases to bilateral breasts, uterus, abdominal lymph nodes, bilateral axillary and supraclavicular lymph nodes, and bone marrow, responded extremely well to an FAP combined chemotherapy as reported here. The patients received four courses of 5-FU (370 mg/m2/day, for five days, continuous infusion), ADM (30 mg/m2 on day 1, i.v.) and CDDP (55 mg/m2 on day 1, i.v.) every 3 weekks in our hospital. This was followed by 7 months of outpatient therapy with 5-FU (550 mg/m2 on day 1, i.v.), ADM (30 mg/m2 on day 1, i.v.) and CBDCA (330 mg/m2 on day 1, i.v.) for every 4 weeks. The complete remission of the primary and metastatic lesions, that was confirmed by the histological examinations, was obtained after 10 months since the initial treatment started. The toxicity was generally moderate, however, the alopecia was severe. The patient has been living for 6 months without any signs of the recurrence after the complete remission obtained.
KW - 5-fluorouracil
KW - carboplatin
KW - cisplatin
KW - doxorubicin
KW - gastric cancer
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M3 - Article
C2 - 8470923
AN - SCOPUS:0027263579
SN - 0385-0684
VL - 20
SP - 643
EP - 646
JO - Japanese Journal of Cancer and Chemotherapy
JF - Japanese Journal of Cancer and Chemotherapy
IS - 5
ER -
