A 48-year-old man was referred to us, of a mass shadow in the infected emphysematous bulla by chest CT scannings. Neither bronchofiberscopic examination nor CT-guided transcutaneous biopsy could yielded a definitive diagnosis. By surgical resection of the extrapleural tumor directly invading the chest wall, poorly differentiated adenocarcinoma was diagnosed. Three cycles of chemotherapy consisting of cisplatin (20mg/m2 x 5 days) and 5- fluorouracil (500mg/m2 x 5 days), and simultaneous hyperfractionated thoracic irradiation (70Gy in a total dose with 1.25Gy x 2, day) were immediately started and the mass shadow markedly regressed. Lung cancer with a coexisting bulla is frequently advanced and considered to have poor prognosis. Chemoradiotherapy may be useful for the treatment of unresectable advanced cases.
- Giant emphysematous bulla
- Lung cancer
ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine