A case of acute hepatitis E virus infection with clinical features indistinguishable from drug-induced liver injury

Masaya Iwamuro, Mitsuhiko Kawaguchi, Ryo Terada, Toshiya Onsawa, Kazuhide Yamamoto, Tatsuya Itoshima, Kazuaki Takahashi

Research output: Contribution to journalArticle

Abstract

We experienced a case of acute hepatitis E virus (HEV) infection with clinical features indistinguishable from drug-induced liver injury. A 71-year old female was admitted to the hospital because of an elevation of serum trasnaminase levels. Kampo medicines had been administered four weeks before, and lymphocyte stimulation tests for Kampo medicines were positive. In consequence, we assumed that drug-induced reaction was the cause of her liver injury. Afterward, however, both immunoglobulin M antibodies against HEV and HEV RNA turned out to be positive. Finally, we diagnosed as acute HEV infection. The patient had no history of a travel abroad, ingestion of a wild boar, deer or goat. She had eaten a pig liver one month before, which was presumed as a source of infection.

Original languageEnglish
Pages (from-to)512-515
Number of pages4
JournalActa Hepatologica Japonica
Volume46
Issue number8
DOIs
Publication statusPublished - Oct 3 2005
Externally publishedYes

ASJC Scopus subject areas

  • Hepatology

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