Abstract
The aim of this single-institution, retrospective, observational case-control study was to evaluate the safety and feasibility of laparoscopic proctocolectomy (PC) for ulcerative colitis (UC), by comparing it with a case-control series of open PC. Twenty UC patients who underwent laparoscopic PC were retrospectively compared with the open PC group of 12 patients matched for age, sex, and urgency of the operation. In the laparoscopic PC group, the operative time was significantly longer, but the amount of blood loss was significantly smaller. The open PC patients underwent an intraoperative blood transfusion significantly more often, and the serum C-reactive protein level on the first postoperative day was significantly higher in the open PC group. In the laparoscopic PC group, the rate of severe postoperative morbidities, grades 3 and 4 on the Clavien-Dindo classification, was significantly lower, and the median length of hospital stay was significantly shorter. Laparoscopic PC for patients with UC showed superior perioperative outcomes to open PC, except for longer operative time.
| Original language | English |
|---|---|
| Pages (from-to) | 267-273 |
| Number of pages | 7 |
| Journal | Acta Medica Okayama |
| Volume | 69 |
| Issue number | 5 |
| Publication status | Published - 2015 |
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Keywords
- Casematched study
- Laparoscopic surgery
- Open proctocolectomy
- Total proctocolectomy
- Ulcerative colitis
ASJC Scopus subject areas
- Medicine(all)
- Biochemistry, Genetics and Molecular Biology(all)
Cite this
A case-matched comparative study of laparoscopic and open total proctocolectomy for ulcerative colitis. / Inada, Ryo; Nagasaka, Takeshi; Kondo, Yoshitaka; Watanabe, Ayako; Toshima, Toshiaki; Kubota, Nobuhito; Kikuch, Satoru; Ishida, Michihiro; Kuroda, Shinji; Mori, Yoshiko; Kishimoto, Hiroyuki; Fujiwara, Toshiyoshi.
In: Acta Medica Okayama, Vol. 69, No. 5, 2015, p. 267-273.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - A case-matched comparative study of laparoscopic and open total proctocolectomy for ulcerative colitis
AU - Inada, Ryo
AU - Nagasaka, Takeshi
AU - Kondo, Yoshitaka
AU - Watanabe, Ayako
AU - Toshima, Toshiaki
AU - Kubota, Nobuhito
AU - Kikuch, Satoru
AU - Ishida, Michihiro
AU - Kuroda, Shinji
AU - Mori, Yoshiko
AU - Kishimoto, Hiroyuki
AU - Fujiwara, Toshiyoshi
PY - 2015
Y1 - 2015
N2 - The aim of this single-institution, retrospective, observational case-control study was to evaluate the safety and feasibility of laparoscopic proctocolectomy (PC) for ulcerative colitis (UC), by comparing it with a case-control series of open PC. Twenty UC patients who underwent laparoscopic PC were retrospectively compared with the open PC group of 12 patients matched for age, sex, and urgency of the operation. In the laparoscopic PC group, the operative time was significantly longer, but the amount of blood loss was significantly smaller. The open PC patients underwent an intraoperative blood transfusion significantly more often, and the serum C-reactive protein level on the first postoperative day was significantly higher in the open PC group. In the laparoscopic PC group, the rate of severe postoperative morbidities, grades 3 and 4 on the Clavien-Dindo classification, was significantly lower, and the median length of hospital stay was significantly shorter. Laparoscopic PC for patients with UC showed superior perioperative outcomes to open PC, except for longer operative time.
AB - The aim of this single-institution, retrospective, observational case-control study was to evaluate the safety and feasibility of laparoscopic proctocolectomy (PC) for ulcerative colitis (UC), by comparing it with a case-control series of open PC. Twenty UC patients who underwent laparoscopic PC were retrospectively compared with the open PC group of 12 patients matched for age, sex, and urgency of the operation. In the laparoscopic PC group, the operative time was significantly longer, but the amount of blood loss was significantly smaller. The open PC patients underwent an intraoperative blood transfusion significantly more often, and the serum C-reactive protein level on the first postoperative day was significantly higher in the open PC group. In the laparoscopic PC group, the rate of severe postoperative morbidities, grades 3 and 4 on the Clavien-Dindo classification, was significantly lower, and the median length of hospital stay was significantly shorter. Laparoscopic PC for patients with UC showed superior perioperative outcomes to open PC, except for longer operative time.
KW - Casematched study
KW - Laparoscopic surgery
KW - Open proctocolectomy
KW - Total proctocolectomy
KW - Ulcerative colitis
UR - http://www.scopus.com/inward/record.url?scp=84947928819&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84947928819&partnerID=8YFLogxK
M3 - Article
VL - 69
SP - 267
EP - 273
JO - Acta Medica Okayama
JF - Acta Medica Okayama
SN - 0386-300X
IS - 5
ER -