The new radical scavenger 12T061C (C20H22O7) has been identified from a culture of Streptomyces species. Spectroscopic elucidation showed that this compound is a new Julichrome family compound. 12T061C shows a potent radical-scavenging activity with an ED50 of 18 μm that is similar to those of the known antioxidant compounds α-tocopherol (ED50 16 μm) and quercetin (ED50 3 μm).
- 2 2-diphenyl-1-picrylhydrazyl (DPPH)
- Streptomyces species
- radical scavenger
ASJC Scopus subject areas
- Organic Chemistry