12T061C, a new Julichrome family radical scavenger from Streptomyces species

Toshikazu Komoda, Naoko Saeki, Yoshitaka Koseki, Hiromasa Kiyota

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Abstract

The new radical scavenger 12T061C (C20H22O7) has been identified from a culture of Streptomyces species. Spectroscopic elucidation showed that this compound is a new Julichrome family compound. 12T061C shows a potent radical-scavenging activity with an ED50 of 18 μm that is similar to those of the known antioxidant compounds α-tocopherol (ED50 16 μm) and quercetin (ED50 3 μm).

Original languageEnglish
Pages (from-to)271-274
Number of pages4
JournalHeterocyclic Communications
Volume20
Issue number5
DOIs
Publication statusPublished - Oct 1 2014

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Keywords

  • 2 2-diphenyl-1-picrylhydrazyl (DPPH)
  • Julichrome
  • radical scavenger
  • Streptomyces species

ASJC Scopus subject areas

  • Organic Chemistry

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