12T061C, a new Julichrome family radical scavenger from Streptomyces species

Toshikazu Komoda, Naoko Saeki, Yoshitaka Koseki, Hiromasa Kiyota

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The new radical scavenger 12T061C (C20H22O7) has been identified from a culture of Streptomyces species. Spectroscopic elucidation showed that this compound is a new Julichrome family compound. 12T061C shows a potent radical-scavenging activity with an ED50 of 18 μm that is similar to those of the known antioxidant compounds α-tocopherol (ED50 16 μm) and quercetin (ED50 3 μm).

Original languageEnglish
Pages (from-to)271-274
Number of pages4
JournalHeterocyclic Communications
Volume20
Issue number5
DOIs
Publication statusPublished - Oct 1 2014

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Tocopherols
Scavenging
Quercetin
Antioxidants

Keywords

  • 2 2-diphenyl-1-picrylhydrazyl (DPPH)
  • Julichrome
  • radical scavenger
  • Streptomyces species

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

12T061C, a new Julichrome family radical scavenger from Streptomyces species. / Komoda, Toshikazu; Saeki, Naoko; Koseki, Yoshitaka; Kiyota, Hiromasa.

In: Heterocyclic Communications, Vol. 20, No. 5, 01.10.2014, p. 271-274.

Research output: Contribution to journalArticle

Komoda, Toshikazu ; Saeki, Naoko ; Koseki, Yoshitaka ; Kiyota, Hiromasa. / 12T061C, a new Julichrome family radical scavenger from Streptomyces species. In: Heterocyclic Communications. 2014 ; Vol. 20, No. 5. pp. 271-274.
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