10'-Chloro-3′,4′-dihydro-2′H-spiro[cyclopropane-1, 7'(6′H)-pyrimido[2,1-a]isoquinolin]-6′-one

Kensuke Okuda, Takashi Hirota, Yuta Nishina, Hiroyuki Ishida

Research output: Contribution to journalArticle

Abstract

In the title compound, C14FH13ClN2O, the fused hydropyrimidine ring adopts an envelope conformation with one of the methylene C atoms at the flap. The three-membered ring is approximately perpendicular to the attached isoquinoline ring system, with a dihedral angle of 89.44(11)°. In the crystal, molecules are linked by a weak C-H⋯π interaction, forming a helical chain along the c axis.

Original languageEnglish
Pages (from-to)o3252
JournalActa Crystallographica Section E: Structure Reports Online
Volume68
Issue number11
DOIs
Publication statusPublished - Nov 1 2012

Keywords

  • R factor = 0.031
  • T = 180 K
  • data-to-parameter ratio = 20.6
  • mean ̄(C-C) = 0.002 Å
  • single-crystal X-ray study
  • wR factor = 0.079

ASJC Scopus subject areas

  • Chemistry(all)
  • Materials Science(all)
  • Condensed Matter Physics

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