Abstract
Pre-treatment with α-tocopherol (α-Toc) potentiated cytotoxicity induction by benzyl isothiocyanate (BITC). Biochemical events related to apoptosis, such as DNA ladder formation and caspase-3 activation, were also enhanced by α-Toc. These results suggest a significant role of the caspase-3 pathway in apoptosis induction regulated by α-Toc in combination.
Original language | English |
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Pages (from-to) | 381-383 |
Number of pages | 3 |
Journal | Bioscience, Biotechnology and Biochemistry |
Volume | 76 |
Issue number | 2 |
DOIs | |
Publication status | Published - 2012 |
Keywords
- Apoptosis
- Benzyl isothiocyanate
- Caspase-3
- HL-60 cells
- α-tocopherol
ASJC Scopus subject areas
- Biotechnology
- Analytical Chemistry
- Biochemistry
- Applied Microbiology and Biotechnology
- Molecular Biology
- Organic Chemistry