• 1581 Citations
  • 22 h-Index
19952019
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Research Output 1995 2019

  • 1581 Citations
  • 22 h-Index
  • 96 Article
  • 12 Conference contribution
  • 1 Review article
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Article
13 Citations (Scopus)

Activation of protease by sol-gel entrapment into organically modified hybrid silicates

Furukawa, S. Y., Ono, T., Ijima, H. & Kawakami, K., 2002, In : Biotechnology Letters. 24, 1, p. 13-16 4 p.

Research output: Contribution to journalArticle

Silicates
Polymethyl Methacrylate
Diatomaceous Earth
Sol-gels
Peptide Hydrolases
23 Citations (Scopus)

Alginate/aminopropyl-silicate/alginate membrane immunoisolatability and insulin secretion of encapsulated islets

Sakai, S., Ono, T., Ijima, H. & Kawakami, K., 2002, In : Biotechnology Progress. 18, 2, p. 401-403 3 p.

Research output: Contribution to journalArticle

calcium alginate
Silicates
insulin secretion
alginates
silicates
19 Citations (Scopus)

Aminopropyl-silicate membrane for microcapsule-shaped bioartificial organs: Control of molecular permeability

Sakai, S., Ono, T., Ijima, H. & Kawakami, K., Jun 15 2002, In : Journal of Membrane Science. 202, 1-2, p. 73-80 8 p.

Research output: Contribution to journalArticle

Bioartificial Organs
Silicates
organs
Capsules
Permeability
29 Citations (Scopus)
Paclitaxel
Blood Vessels
Neoplasms
Therapeutics
Colon
6 Citations (Scopus)

A versatile biodegradable polymer with a thermo-reversible/irreversible transition

Tanimoto, F., Kitamura, Y., Ono, T. & Yoshizawa, H., Mar 24 2010, In : ACS Applied Materials and Interfaces. 2, 3, p. 606-610 5 p.

Research output: Contribution to journalArticle

Biodegradable polymers
Nanospheres
Polymers
Phase transitions
Imides
14 Citations (Scopus)

Behavior of enclosed sol- and gel-alginates in vivo

Sakai, S., Ono, T., Ijima, H. & Kawakami, K., Dec 2004, In : Biochemical Engineering Journal. 22, 1, p. 19-24 6 p.

Research output: Contribution to journalArticle

Alginates
Alginate
Polymethyl Methacrylate
Sols
Gels
4 Citations (Scopus)

Catalytic capabilities of lipase immobilized into organically modified silicates by sol-gel method

Furukawa, S. Y., Ono, T., Ijima, H. & Kawakami, K., 2000, In : Kagaku Kogaku Ronbunshu. 26, 6, p. 885-886 2 p.

Research output: Contribution to journalArticle

Silicates
Lipases
Lipase
Sol-gel process
Diatomaceous Earth
18 Citations (Scopus)

Catalytic oxidation of o-phenylenediamine by cytochrome c encapsulated in reversed micelles

Ono, T., Kawakami, K., Goto, M. & Furusaki, S., Jan 22 2001, In : Journal of Molecular Catalysis B: Enzymatic. 11, 4-6, p. 955-959 5 p.

Research output: Contribution to journalArticle

Catalytic oxidation
Micelles
Cytochromes c
Proteins
Peroxidases
11 Citations (Scopus)

Catalytic properties of novel reversed micellar system on trans-esterification by α-chymotrypsin in organic media

Iskandar, L., Ono, T., Kamiya, N., Goto, M., Nakashio, F. & Furusaki, S., Sep 1998, In : Biochemical Engineering Journal. 2, 1, p. 29-33 5 p.

Research output: Contribution to journalArticle

Esterification
Transesterification
Chymotrypsin
Micelles
Sodium
1 Citation (Scopus)

Characteristics of compacted plasmid DNA by high pressurization.

Kimura, T., Horiuchi, K., Kurita, K., Ono, T., Yoshizawa, H., Fujisato, T. & Kishida, A., 2007, In : Nucleic acids symposium series (2004). 51, p. 343-344 2 p.

Research output: Contribution to journalArticle

Plasmids
DNA
Pressure
Superhelical DNA
Hydrodynamics
36 Citations (Scopus)
Emulsification
Emulsions
Microspheres
Microfluidics
emulsions
45 Citations (Scopus)

Control of molecular weight cut-off immunoisolation by multilayering glycol chitosan-alginate polyion complex on alginate-based microcapsules

Sakai, S., Ono, T., Ijima, H. & Kawakami, K., 2000, In : Journal of Microencapsulation. 17, 6, p. 691-699 9 p.

Research output: Contribution to journalArticle

Alginate
Glycols
Chitosan
globulins
Capsules
1 Citation (Scopus)

Control of Transport Characteristic of Membrane by Multi-layering of Polyelectrolyte Complex Toward Microcapsule-shaped Bioartificial Pancreas

Saka, S., Ono, T., Ijima, H. & Kawakami, K., 2001, In : Kagaku Kogaku Ronbunshu. 27, 2, p. 165-168 4 p.

Research output: Contribution to journalArticle

Polyelectrolytes
Capsules
Membranes
Alginate
Globulins
20 Citations (Scopus)

Coupling microreaction technologies, polymer chemistry, and processing to produce polymeric micro and nanoparticles with controlled size, morphology, and composition

Serra, C. A., Cortese, B., Khan, I. U., Anton, N., de Croon, M. H. J. M., Hessel, V., Ono, T. & Vandamme, T., Sep 2013, In : Macromolecular Reaction Engineering. 7, 9, p. 414-439 26 p.

Research output: Contribution to journalArticle

Polymers
Nanoparticles
Cosmetics
Biotechnology
Processing
6 Citations (Scopus)

Design and evaluation of emulsion generation device using ultrasonic vibration and microchannel

Kanda, T., Harada, T., Tominaga, Y., Suzumori, K., Ono, T., Iwabuchi, S., Ito, K., Ogawara, K. I., Higaki, K. & Yoshizawa, Y., Jul 2011, In : Japanese Journal of Applied Physics. 50, 7 PART 2, 07HE24.

Research output: Contribution to journalArticle

Ultrasonic devices
microchannels
Microchannels
emulsions
Emulsions
8 Citations (Scopus)

Design of a new static micromixer having simple structure and excellent mixing performance

Kamio, E., Ono, T. & Yoshizawa, H., 2009, In : Lab on a Chip - Miniaturisation for Chemistry and Biology. 9, 12, p. 1809-1812 4 p.

Research output: Contribution to journalArticle

Stainless Steel
Flow of fluids
Stainless steel
6 Citations (Scopus)

Design of polylactide-grafted copolymeric stabilizer for dispersion polymerization of D,L-lactide

Muranaka, M., Yoshizawa, H. & Ono, T., 2009, In : Colloid and Polymer Science. 287, 5, p. 525-532 8 p.

Research output: Contribution to journalArticle

Microspheres
polymerization
Polymerization
Micelles
Copolymers
60 Citations (Scopus)

Design of surfactants suitable for protein extraction by reversed micelles

Goto, M., Ono, T., Nakashio, F. & Hatton, T. A., Apr 5 1997, In : Biotechnology and Bioengineering. 54, 1, p. 26-32 7 p.

Research output: Contribution to journalArticle

Micelles
Surface-Active Agents
Surface active agents
Proteins
Heptanes
46 Citations (Scopus)

Development and characterization of a silica monolith immobilized enzyme micro-bioreactor

Kawakami, K., Sera, Y., Sakai, S., Ono, T. & Ijima, H., Jan 5 2005, In : Industrial and Engineering Chemistry Research. 44, 1, p. 236-240 5 p.

Research output: Contribution to journalArticle

Immobilized Enzymes
Bioreactors
Silicon Dioxide
bioreactor
Enzymes
14 Citations (Scopus)

Development of co-culture system of hepatocytes with bone marrow cells for expression and maintenance of hepatic functions

Murakami, S., Ijima, H., Ono, T. & Kawakami, K., Feb 2004, In : International Journal of Artificial Organs. 27, 2, p. 118-126 9 p.

Research output: Contribution to journalArticle

Coculture Techniques
Cell culture
Bone Marrow Cells
Hepatocytes
Bone
68 Citations (Scopus)

Development of mammalian cell-enclosing subsieve-size agarose capsules (

Sakai, S., Kawabata, K., Ono, T., Ijima, H. & Kawakami, K., Aug 2005, In : Biomaterials. 26, 23, p. 4786-4792 7 p.

Research output: Contribution to journalArticle

Sepharose
Paraffins
Capsules
Mineral Oil
Cells
2 Citations (Scopus)

Digoxin transport by renal proximal tubule cells is enhanced by adhesive synthetic RGD peptide

Ijima, H., Kuroda, S., Ono, T. & Kawakami, K., Jan 2007, In : International Journal of Artificial Organs. 30, 1, p. 25-33 9 p.

Research output: Contribution to journalArticle

Proximal Kidney Tubule
Digoxin
Cell adhesion
Collagen
Adhesives
19 Citations (Scopus)

DNA extraction by cationic reverse micelles

Goto, M., Momota, A. & Ono, T., May 2004, In : Journal of Chemical Engineering of Japan. 37, 5, p. 662-668 7 p.

Research output: Contribution to journalArticle

Micelles
DNA
Cationic surfactants
Surface-Active Agents
Surface active agents
6 Citations (Scopus)

Effect of diglucosamine on the entrapment of protein into liposomes

Murakami, S., Ono, T., Sakai, S., Ijima, H. & Kawakami, K., Jul 2006, In : Journal of Liposome Research. 16, 2, p. 103-112 10 p.

Research output: Contribution to journalArticle

Liposomes
Disaccharides
Bovine Serum Albumin
Proteins
Particle Size
36 Citations (Scopus)

Effect of imprinting sol-gel immobilized lipase with chiral template substrates in esterification of (R)-(+)- and (S)-(-)-glycidol

Furukawa, S. Y., Ono, T., Ijima, H. & Kawakami, K., Mar 7 2002, In : Journal of Molecular Catalysis B: Enzymatic. 17, 1, p. 23-28 6 p.

Research output: Contribution to journalArticle

glycidol
Esterification
Lipases
Polymethyl Methacrylate
Lipase
7 Citations (Scopus)

Effect of organic solvents on extraction behaviour of cytochrome c using reversed micellar solutions

Ono, T., Miyazaki, T., Goto, M. & Nakashio, F., 1996, In : Solvent Extraction Research and Development. 1996, 3, p. 1-9 9 p.

Research output: Contribution to journalArticle

Cytochromes c
Organic solvents
Proteins
Micelles
Hexanes

Effect of pre-emulsion state for a generation of nano-emulsion by an ultrasonic vibration device

Onishihi, K., Kanda, T., Ono, T., Toyota, S., Imai, Y., Ogawara, K. I., Higaki, K. & Suzumori, K., Jan 1 2018, In : IEEJ Transactions on Sensors and Micromachines. 138, 9, p. 394-400 7 p.

Research output: Contribution to journalArticle

Vibrations (mechanical)
Emulsions
Ultrasonics
Microchannels
5 Citations (Scopus)

Effects of dispersion stabilizer and reaction solvent on forming monodisperse polystyrene microspheres by dispersion polymerization

Nakashima, T. & Ono, T., 2008, In : Colloid and Polymer Science. 286, 14-15, p. 1587-1592 6 p.

Research output: Contribution to journalArticle

Stabilizers (agents)
Polystyrenes
Microspheres
polystyrene
polymerization

Effects of lipid composition on entrapment of proteins into phosphatidylglycerol-containing liposomes

Murakami, S., Fujita, T., Ono, T., Sakai, S., Ijima, H. & Kawakami, K., 2006, In : Kagaku Kogaku Ronbunshu. 32, 6, p. 514-517 4 p.

Research output: Contribution to journalArticle

Phosphatidylglycerols
Liposomes
Lipids
Proteins
Chemical analysis
14 Citations (Scopus)
Porphyrins
Nanoparticles
Neoplasms
Colon
Esters
13 Citations (Scopus)

Emulsion generating microchannel device oscillated by 2.25MHz ultrasonic vibrator

Harada, T., Kanda, T., Suzumori, K., Ono, T., Iwabuchi, S., Ito, K., Ogawara, K. I. & Higaki, K., Jul 2010, In : Japanese Journal of Applied Physics. 49, 7 PART 2, 07HE13.

Research output: Contribution to journalArticle

Vibrators
microchannels
Microchannels
emulsions
Emulsions
3 Citations (Scopus)

Enhanced angiogenesis in bFGF-containing scaffold promoted viability of enclosed hepatocytes and maintained hepatospecific glycogen storage capacity

Takei, T., Ijima, H., Sakai, S., Ono, T. & Kawakami, K., Nov 20 2005, In : Journal of Chemical Engineering of Japan. 38, 11, p. 913-917 5 p.

Research output: Contribution to journalArticle

Fibroblast Growth Factor 2
Fibroblasts
Glycogen
Scaffolds
Rats
14 Citations (Scopus)

Enhancement of activity of sol-gel immobilized lipase in organic media by pretreatment with substrate analogues

Furukawa, S. Y., Ono, T., Ijima, H. & Kawakami, K., Sep 28 2001, In : Journal of Molecular Catalysis B: Enzymatic. 15, 1-3, p. 65-70 6 p.

Research output: Contribution to journalArticle

Lipases
Polymethyl Methacrylate
Lipase
Sol-gels
Gels
10 Citations (Scopus)

Enhancement of liver-specific functions of primary rat hepatocytes co-cultured with bone marrow cells on tissue culture-treated polystyrene surfaces

Ijima, H., Murakami, S., Matsuo, T., Takei, T., Ono, T. & Kawakami, K., Aug 2005, In : Journal of Artificial Organs. 8, 2, p. 104-109 6 p.

Research output: Contribution to journalArticle

Tissue culture
Polystyrenes
Bone Marrow Cells
Liver
Rats
7 Citations (Scopus)
glycidol
Silicates
Butyrates
Transesterification
Peptide Hydrolases
Animal cell culture
Hydrothermal synthesis
Gypsum
Chemical engineering
Hydroxyapatite
4 Citations (Scopus)

Evaluating the performance of a hybrid artificial liver support system with a recoverable hepatic failure rat model

Ijima, H., Noguchi, A., Katsuno, T., Ono, T., Nakazawa, K., Funatsu, K. & Kawakami, K., 2001, In : Annals of the New York Academy of Sciences. 944, p. 344-349 6 p.

Research output: Contribution to journalArticle

Artificial Liver
Liver Failure
Liver
Rats
Warm Ischemia
32 Citations (Scopus)

Extraction and activity of chymotrypsin using AOT-DOLPA mixed reversed micellar systems

Goto, M., Ishikawa, Y., Ono, T., Nakashio, F. & Alan Hatton, T., Sep 1998, In : Biotechnology Progress. 14, 5, p. 729-734 6 p.

Research output: Contribution to journalArticle

phosphoric acid
Chymotrypsin
Micelles
chymotrypsin
micelles
48 Citations (Scopus)

Extraction behavior of hemoglobin using reversed micelles by dioleyl phosphoric acid

Ono, T., Goto, M., Nakashio, F. & Hatton, T. A., Nov 1996, In : Biotechnology Progress. 12, 6, p. 793-800 8 p.

Research output: Contribution to journalArticle

phosphoric acid
Micelles
micelles
hemoglobin
Hemoglobins
31 Citations (Scopus)

Extraction of DNA by reversed micelles

Goto, M., Ono, T., Horiuchi, A. & Furusaki, S., 1999, In : Journal of Chemical Engineering of Japan. 32, 1, p. 123-125 3 p.

Research output: Contribution to journalArticle

Micelles
DNA
Cationic surfactants
Deoxyribonucleotides
Coulomb interactions
7 Citations (Scopus)

Extraction of ethyl ester of polyunsaturated fatty acids by utilizing slug flow prepared by microreactor

Seike, Y., Kamio, E., Ono, T. & Yoshizawa, H., Dec 20 2007, In : Journal of Chemical Engineering of Japan. 40, 12, p. 1076-1084 9 p.

Research output: Contribution to journalArticle

Polyunsaturated fatty acids
Unsaturated Fatty Acids
Esters
Silver Nitrate
Nitrates
32 Citations (Scopus)

Fabrication of endothelialized tube in collagen gel as starting point for self-developing capillary-like network to construct three-dimensional organs in vitro

Takei, T., Sakai, S., Ono, T., Ijima, H. & Kawakami, K., Sep 5 2006, In : Biotechnology and Bioengineering. 95, 1, p. 1-7 7 p.

Research output: Contribution to journalArticle

Collagen
Gels
Endothelial cells
Fabrication
Endothelial Cells
8 Citations (Scopus)
cytochrome c
Cytochromes c
Surface-Active Agents
surfactants
case studies
18 Citations (Scopus)

Formulation and evaluation of paclitaxel-loaded polymeric nanoparticles composed of polyethylene glycol and polylactic acid block copolymer

Araki, T., Kono, Y., Ogawara, K. I., Watanabe, T., Ono, T., Kimura, T. & Higaki, K., Aug 2012, In : Biological and Pharmaceutical Bulletin. 35, 8, p. 1306-1313 8 p.

Research output: Contribution to journalArticle

Paclitaxel
Nanoparticles
Neoplasms
poly(lactic acid)
Colon
1 Citation (Scopus)

Free-Standing Metal Films Prepared via Electroless Plating at Liquid-Liquid Interfaces

Tsuneyoshi, T., Yohaze, Y., Watanabe, T. & Ono, T., Nov 6 2018, In : Langmuir. 34, 44, p. 13183-13191 9 p.

Research output: Contribution to journalArticle

liquid-liquid interfaces
Electroless plating
plating
metal films
palladium
8 Citations (Scopus)
Styrene
Copolymerization
Polymerization
Sodium
Sodium Hydroxide
2 Citations (Scopus)
Styrene
Copolymerization
Polymerization
Water content
Monomers
11 Citations (Scopus)

Higher viscous solution induces smaller droplets for cell-enclosing capsules in a co-flowing stream

Sakai, S., Kawabata, K., Ono, T., Ijima, H. & Kawakami, K., May 2005, In : Biotechnology Progress. 21, 3, p. 994-997 4 p.

Research output: Contribution to journalArticle

droplets
Capsules
Viscosity
viscosity
aqueous solutions
1 Citation (Scopus)

Hydrothermal synthesis of porous hydroxyapatite plates from gypsum: Use as an animal cell culture substratum

Ijima, H., Nakashima, M., Furuta, S., Ono, T. & Kawakami, K., Apr 2004, In : Journal of Chemical Engineering of Japan. 37, 4, p. 531-535 5 p.

Research output: Contribution to journalArticle

Animal cell culture
Calcium Sulfate
Hydrothermal synthesis
Gypsum
Durapatite
11 Citations (Scopus)

Hydroxyapatite for use as an animal cell culture substratum obtained by an alternate soaking process

Ijima, H., Ohchi, T., Ono, T. & Kawakami, K., Aug 15 2004, In : Biochemical Engineering Journal. 20, 2-3, p. 155-161 7 p.

Research output: Contribution to journalArticle

Animal cell culture
Durapatite
Hydroxyapatite
Cell Culture Techniques
CHO Cells