• 480 Citations
  • 11 h-Index
20092019
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Research Output 2009 2019

  • 480 Citations
  • 11 h-Index
  • 33 Article
  • 1 Review article
2019
benzyl isothiocyanate
Carica
Distillation
papayas
distillation

Covalent Modification of Phosphatidylethanolamine by Benzyl Isothiocyanate and the Resultant Generation of Ethanolamine Adduct as Its Metabolite

Nakamura, T., Hirakawa, M., Nakamura, Y., Ishisaka, A., Kitamoto, N., Murakami, A. & Kato, Y., Apr 15 2019, In : Chemical Research in Toxicology. 32, 4, p. 638-644 7 p.

Research output: Contribution to journalArticle

Ethanolamine
Metabolites
Sulfhydryl Compounds
phosphatidylethanolamine
benzyl isothiocyanate

Dynamics of the Cellular Metabolism of Leptosperin Found in Manuka Honey

Kato, Y., Kawai, M., Kawai, S., Okano, Y., Rokkaku, N., Ishisaka, A., Murota, K., Nakamura, T., Nakamura, Y. & Ikushiro, S., Oct 2 2019, In : Journal of agricultural and food chemistry. 67, 39, p. 10853-10862 10 p.

Research output: Contribution to journalArticle

syringic acid
Honey
Metabolism
honey
metabolism

The golgin protein giantin regulates interconnections between Golgi stacks

Satoh, A., Hayashi-Nishino, M., Shakuno, T., Masuda, J., Koreishi, M., Murakami, R., Nakamura, Y., Nakamura, T., Abe-Kanoh, N., Honjo, Y., Malsam, J., Yu, S. & Nishino, K., Jan 1 2019, In : Frontiers in Cell and Developmental Biology. 7, AUG, 160.

Research output: Contribution to journalArticle

Open Access
Glycosylation
Proteins
Electron Microscope Tomography
macrogolgin
Microtubules
2018

Benzyl isothiocyanate ameliorates lipid accumulation in 3T3-L1 preadipocytes during adipocyte differentiation

Liang, Y., Sasaki, I., Takeda, Y., Zhu, B., Munemasa, S., Nakamura, T., Murata, Y. & Nakamura, Y., Jan 1 2018, In : Bioscience, Biotechnology and Biochemistry. 82, 12, p. 2130-2139 10 p.

Research output: Contribution to journalArticle

Adipocytes
Lipids
CCAAT-Enhancer-Binding Proteins
Phosphorylation
Carica
6 Citations (Scopus)

Lymphatic metabolites of quercetin after intestinal administration of quercetin-3-glucoside and its aglycone in rats

Nakamura, T., Kinjo, C., Nakamura, Y., Kato, Y., Nishikawa, M., Hamada, M., Nakajima, N., Ikushiro, S. & Murota, K., May 1 2018, In : Archives of Biochemistry and Biophysics. 645, p. 126-136 11 p.

Research output: Contribution to journalArticle

Quercetin
Metabolites
Lymph
Rats
Plasmas
2 Citations (Scopus)
Phosphorylation
Cyclodextrins
Colorectal Neoplasms
Cells
Modulation
11 Citations (Scopus)

Physiological relevance of covalent protein modification by dietary isothiocyanates

Nakamura, T., AbeKanoh, N. & Nakamura, Y., Jan 1 2018, In : Journal of Clinical Biochemistry and Nutrition. 62, 1, p. 11-19 9 p.

Research output: Contribution to journalReview article

Isothiocyanates
Diet Therapy
Dietary Proteins
Proteins
Vegetables
2017
3 Citations (Scopus)
Enzyme activity
Peptidyl-Dipeptidase A
Enzyme inhibition
Hydrogen Peroxide
Zinc Sulfate
5 Citations (Scopus)

3,4-Dihydroxyphenylacetic acid is a potential aldehyde dehydrogenase inducer in murine hepatoma Hepa1c1c7 cells

Liu, Y., Kurita, A., Nakashima, S., Zhu, B., Munemasa, S., Nakamura, T., Murata, Y. & Nakamura, Y., Oct 1 2017, In : Bioscience, Biotechnology, and Biochemistry. 81, 10, p. 1978-1983 6 p.

Research output: Contribution to journalArticle

3,4-Dihydroxyphenylacetic Acid
Aldehyde Dehydrogenase
Hepatocellular Carcinoma
Acetaldehyde
Cytotoxicity
6 Citations (Scopus)

Benzyl isothiocyanate ameliorates acetaldehyde-induced cytotoxicity by enhancing aldehyde dehydrogenase activity in murine hepatoma Hepa1c1c7 cells

Liu, Y., Yamanaka, M., Abe-Kanoh, N., Liu, X., Zhu, B., Munemasa, S., Nakamura, T., Murata, Y. & Nakamura, Y., Oct 1 2017, In : Food and Chemical Toxicology. 108, p. 305-313 9 p.

Research output: Contribution to journalArticle

benzyl isothiocyanate
aldehyde dehydrogenase
Aldehyde Dehydrogenase
Acetaldehyde
acetaldehyde
4 Citations (Scopus)

Chitosan signaling in guard cells requires endogenous salicylic acid

Prodhan, M. Y., Issak, M., Nakamura, T., Munemasa, S., Nakamura, Y. & Murata, Y., 2017, In : Bioscience, Biotechnology and Biochemistry. 81, 8, p. 1536-1541 6 p.

Research output: Contribution to journalArticle

Salicylic Acid
Chitosan
Reactive Oxygen Species
Plant Growth Regulators
Calcium
3 Citations (Scopus)

Exogenous proline enhances the sensitivity of Tobacco BY-2 cells to arsenate

Nahar, M. N. E. N., Islam, M. M., Hoque, M. A., Yonezawa, A., Prodhan, M. Y., Nakamura, T., Nakamura, Y., Munemasa, S. & Murata, Y., 2017, In : Bioscience, Biotechnology and Biochemistry. 81, 9, p. 1726-1731 6 p.

Research output: Contribution to journalArticle

Tobacco
Proline
Cell growth
Growth
Evans Blue
12 Citations (Scopus)

Inhibition of phosphatidylinositide 3-kinase ameliorates antiproliferation by benzyl isothiocyanate in human colon cancer cells

Liu, X., Takano, C., Shimizu, T., Yokobe, S., Abe-Kanoh, N., Zhu, B., Nakamura, T., Munemasa, S., Murata, Y. & Nakamura, Y., Sep 9 2017, In : Biochemical and Biophysical Research Communications. 491, 1, p. 209-216 8 p.

Research output: Contribution to journalArticle

Colonic Neoplasms
Phosphotransferases
Cells
Colorectal Neoplasms
Non-Receptor Type 1 Protein Tyrosine Phosphatase
2 Citations (Scopus)
Colonic Neoplasms
Phosphotransferases
Cells
Molecules
Chemical activation
12 Citations (Scopus)

Oleuropein aglycone enhances UCP1 expression in brown adipose tissue in high-fat-diet-induced obese rats by activating β-adrenergic signaling

Oi-Kano, Y., Iwasaki, Y., Nakamura, T., Watanabe, T., Goto, T., Kawada, T., Watanabe, K. & Iwai, K., Feb 1 2017, In : Journal of Nutritional Biochemistry. 40, p. 209-218 10 p.

Research output: Contribution to journalArticle

Brown Adipose Tissue
High Fat Diet
Nutrition
Adrenergic Agents
Rats
2016
1 Citation (Scopus)

Activation of transient receptor potential ankyrin 1 by quercetin and its analogs

Nakamura, T., Miyoshi, N., Ishii, T., Nishikawa, M., Ikushiro, S. & Watanabe, T., 2016, In : Bioscience, Biotechnology and Biochemistry. 80, 5, p. 949-954 6 p.

Research output: Contribution to journalArticle

Ankyrins
Quercetin
Chemical activation
Flavonoids
TRPV Cation Channels
4 Citations (Scopus)

A novel tag-free probe for targeting molecules interacting with a flavonoid catabolite

Nakashima, S., Liu, Z., Yamaguchi, Y., Saiki, S., Munemasa, S., Nakamura, T., Murata, Y. & Nakamura, Y., Sep 1 2016, In : Biochemistry and Biophysics Reports. 7, p. 240-245 6 p.

Research output: Contribution to journalArticle

3,4-Dihydroxyphenylacetic Acid
Flavonoids
Molecules
Azides
Proteins
3 Citations (Scopus)
Catechin
peptidyl-dipeptidase A
Enzyme activity
Peptidyl-Dipeptidase A
flavanols
2014
3 Citations (Scopus)
tocotrienols
tocopherols
fibroblasts
cell membranes
cholesterol
15 Citations (Scopus)

Plasma metabolites of dietary flavonoids after combination meal consumption with onion and tofu in humans

Nakamura, T., Murota, K., Kumamoto, S., Misumi, K., Bando, N., Ikushiro, S., Takahashi, N., Sekido, K., Kato, Y. & Terao, J., Feb 2014, In : Molecular Nutrition and Food Research. 58, 2, p. 310-317 8 p.

Research output: Contribution to journalArticle

Soy Foods
tofu
Onions
Quercetin
Flavonoids
7 Citations (Scopus)

The human bitter taste receptor hTAS2R39 is the primary receptor for the bitterness of theaflavins

Yamazaki, T., Sagisaka, M., Ikeda, R., Nakamura, T., Matsuda, N., Ishii, T., Nakayama, T. & Watanabe, T., 2014, In : Bioscience, Biotechnology and Biochemistry. 78, 10, p. 1753-1756 4 p.

Research output: Contribution to journalArticle

theaflavin
theaflavine gallate
2013
6 Citations (Scopus)

Immunomodulatory activity of enzymatically synthesized glycogen and its digested metabolite in a co-culture system consisting of differentiated Caco-2 cells and RAW264.7 macrophages

Yasuda, M., Furuyashiki, T., Nakamura, T., Kakutani, R., Takata, H. & Ashida, H., Sep 2013, In : Food and Function. 4, 9, p. 1387-1393 7 p.

Research output: Contribution to journalArticle

Caco-2 Cells
coculture
Coculture Techniques
Glycogen
glycogen
4 Citations (Scopus)

Non-selective distribution of isomeric cholesterol hydroperoxides to microdomains in cell membranes and activation of matrix metalloproteinase activity in a model of dermal cells

Nakamura, T., Noma, A., Shimada, S., Ishii, N., Bando, N., Kawai, Y. & Terao, J., 2013, In : Chemistry and Physics of Lipids. 174, p. 17-23 7 p.

Research output: Contribution to journalArticle

Cell membranes
Matrix Metalloproteinases
Chemical activation
Cell Membrane
Skin
19 Citations (Scopus)

Plasma HDL reduces nonesterified fatty acid hydroperoxides originating from oxidized LDL: A mechanism for its antioxidant ability

Kotosai, M., Shimada, S., Kanda, M., Matsuda, N., Sekido, K., Shimizu, Y., Tokumura, A., Nakamura, T., Murota, K., Kawai, Y. & Terao, J., Jun 2013, In : Lipids. 48, 6, p. 569-578 10 p.

Research output: Contribution to journalArticle

Lipid Peroxides
HDL Lipoproteins
Nonesterified Fatty Acids
Antioxidants
Plasmas
2012
21 Citations (Scopus)

Absorption and metabolism of 4-hydroxyderricin and xanthoangelol after oral administration of Angelica keiskei (Ashitaba) extract in mice

Nakamura, T., Tokushima, T., Kawabata, K., Yamamoto, N., Miyamoto, M. & Ashida, H., May 2012, In : Archives of Biochemistry and Biophysics. 521, 1-2, p. 71-76 6 p.

Research output: Contribution to journalArticle

Angelica
Metabolism
Oral Administration
Tissue
Metabolites
24 Citations (Scopus)

Comparative analysis of carbohydrate-binding specificities of two anti-glycogen monoclonal antibodies using ELISA and surface plasmon resonance

Nakamura-Tsuruta, S., Yasuda, M., Nakamura, T., Shinoda, E., Furuyashiki, T., Kakutani, R., Takata, H., Kato, Y. & Ashida, H., Mar 1 2012, In : Carbohydrate Research. 350, p. 49-54 6 p.

Research output: Contribution to journalArticle

Surface Plasmon Resonance
Surface plasmon resonance
Glycogen
Enzyme-Linked Immunosorbent Assay
Monoclonal Antibodies
31 Citations (Scopus)

Fermented tea improves glucose intolerance in mice by enhancing translocation of glucose transporter 4 in skeletal muscle

Yamashita, Y., Wang, L., Tinshun, Z., Nakamura, T. & Ashida, H., Nov 14 2012, In : Journal of Agricultural and Food Chemistry. 60, 45, p. 11366-11371 6 p.

Research output: Contribution to journalArticle

glucose transporters
Glucose Intolerance
Facilitative Glucose Transport Proteins
Tea
tea
2011
122 Citations (Scopus)

Accumulation of orally administered quercetin in brain tissue and its antioxidative effects in rats

Ishisaka, A., Ichikawa, S., Sakakibara, H., Piskula, M. K., Nakamura, T., Kato, Y., Ito, M., Miyamoto, K. I., Tsuji, A., Kawai, Y. & Terao, J., Oct 1 2011, In : Free Radical Biology and Medicine. 51, 7, p. 1329-1336 8 p.

Research output: Contribution to journalArticle

Quercetin
Rats
Brain
Tissue
High performance liquid chromatography
5 Citations (Scopus)

Possible evidence of contamination by catechins in deconjugation enzymes from Helix pomatia and Abalone entrails

Nakamura, T., Tanaka, R. & Ashida, H., 2011, In : Bioscience, Biotechnology and Biochemistry. 75, 8, p. 1506-1510 5 p.

Research output: Contribution to journalArticle

Catechin
Sulfatases
Glucuronidase
Contamination
Enzymes
2010
8 Citations (Scopus)

Immunochemical detection of food-derived isothiocyanate as a lysine conjugate

Nakamura, T., Kitamoto, N., Osawa, T. & Kato, Y., 2010, In : Bioscience, Biotechnology and Biochemistry. 74, 3, p. 536-540 5 p.

Research output: Contribution to journalArticle

Carica
Wasabia
Lysine
Food
Antibodies
50 Citations (Scopus)

α-Oligoglucosylation of a sugar moiety enhances the bioavailability of quercetin glucosides in humans

Murota, K., Matsuda, N., Kashino, Y., Fujikura, Y., Nakamura, T., Kato, Y., Shimizu, R., Okuyama, S., Tanaka, H., Koda, T., Sekido, K. & Terao, J., Sep 2010, In : Archives of Biochemistry and Biophysics. 501, 1, p. 91-97 7 p.

Research output: Contribution to journalArticle

Quercetin
Glucosides
Sugars
Biological Availability
Metabolites
2009
51 Citations (Scopus)

Covalent modification of lysine residues by allyl isothiocyanate in physiological conditions: Plausible transformation of isothiocyanate from thiol to amine

Nakamura, T., Kawai, Y., Kitamoto, N., Osawa, T. & Kato, Y., Mar 16 2009, In : Chemical Research in Toxicology. 22, 3, p. 536-542 7 p.

Research output: Contribution to journalArticle

Sulfhydryl Compounds
Lysine
Amines
Acetylcysteine
Bovine Serum Albumin
40 Citations (Scopus)

Quantification of modified tyrosines in healthy and diabetic human urine using liquid chromatography/tandem mass spectrometry

Kato, Y., Dozaki, N., Nakamura, T., Kitamoto, N., Yoshida, A., Naito, M., Kitamura, M. & Osawa, T., Jan 2009, In : Journal of Clinical Biochemistry and Nutrition. 44, 1, p. 67-78 12 p.

Research output: Contribution to journalArticle

Liquid chromatography
Tandem Mass Spectrometry
Liquid Chromatography
Mass spectrometry
Tyrosine