• 1368 Citations
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19982019
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Research Output 1998 2019

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2019

Alteration of Membrane Physicochemical Properties by Two Factors for Membrane Protein Integration

Nomura, K., Yamaguchi, T., Mori, S., Fujikawa, K., Nishiyama, K. I., Shimanouchi, T., Tanimoto, Y., Morigaki, K. & Shimamoto, K., Jan 1 2019, In : Biophysical Journal.

Research output: Contribution to journalArticle

Open Access
Integrases
Membrane Proteins
Diglycerides
Membranes
Membrane Lipids
Liposomes
Membranes
Gels
Stereoselectivity
Isomers
1 Citation (Scopus)

Kinetic pH Titration to Predict the Acid and Hydrothermal Conditions for the Hydrolysis of Disaccharides: Use of a Microcapillary System

Shimanouchi, T., Mano, R., Yoshioka, Y., Fukuda, A., Park, K. M. & Kimura, Y., Jan 1 2019, In : Journal of Chemistry. 2019, 3985915.

Research output: Contribution to journalArticle

Disaccharides
Titration
Hydrolysis
Kinetics
Acids

Recent Development of Optimization of Lyophilization Process

Kawasaki, H., Shimanouchi, T. & Kimura, Y., Jan 1 2019, In : Journal of Chemistry. 2019, 9502856.

Research output: Contribution to journalArticle

Open Access
Strategic materials
Drying
Ice
Mathematical models
Crystals

Structural and physicochemical characteristics of granular malic acid-treated sweet potato starch containing heat-stable resistant starch

Kwon, C., Kim, H. R., Moon, T. W., Lee, S. H., Lee, C. J. & Shimanouchi, T., Jan 1 2019, In : Journal of Chemistry. 2019, 2903252.

Research output: Contribution to journalArticle

Open Access
Starch
Cooking
Substitution reactions
Hot Temperature
malic acid
1 Citation (Scopus)

Temperature Measurement by Sublimation Rate as a Process Analytical Technology Tool in Lyophilization

Kawasaki, H., Shimanouchi, T., Sawada, H., Hosomi, H., Hamabe, Y. & Kimura, Y., Jan 1 2019, In : Journal of Pharmaceutical Sciences.

Research output: Contribution to journalArticle

Sublimation
Freeze Drying
Technology
Temperature
Endpoint Determination
2018

Design of Pyrene-Fatty Acid Conjugates for Real-Time Monitoring of Drug Delivery and Controllability of Drug Release

Hayashi, K., Mitsuyoshi, Y., Kamei, T., Shimanouchi, T., Suga, K., Okamoto, Y., Nakamura, H. & Umakoshi, H., Jan 1 2018, In : ACS Omega. 3, 3, p. 3572-3580 9 p.

Research output: Contribution to journalArticle

Drug Carriers
Pyrene
Controllability
Drug delivery
Fatty acids
2 Citations (Scopus)

Effect of controlled nucleation of ice crystals on the primary drying stage during lyophilization

Kawasaki, H., Shimanouchi, T., Takahashi, K. & Kimura, Y., Jan 1 2018, In : Chemical and Pharmaceutical Bulletin. 66, 12, p. 1122-1130 9 p.

Research output: Contribution to journalArticle

Freeze Drying
Ice
Drying
Nucleation
Crystals
1 Citation (Scopus)

Effect of phosphatidylserine and cholesterol on membrane-mediated fibril formation by the N-terminal amyloidogenic fragment of apolipoprotein A-I

Mizuguchi, C., Nakamura, M., Kurimitsu, N., Ohgita, T., Nishitsuji, K., Baba, T., Shigenaga, A., Shimanouchi, T., Okuhira, K., Otaka, A. & Saito, H., Dec 1 2018, In : Scientific Reports. 8, 1, 5497.

Research output: Contribution to journalArticle

Phosphatidylserines
Apolipoprotein A-I
Cholesterol
Membranes
Lipids
2 Citations (Scopus)

Scale-up procedure for primary drying process in lyophilizer by using the vial heat transfer and the drying resistance

Kawasaki, H., Shimanouchi, T., Yamamoto, M., Takahashi, K. & Kimura, Y., Jan 1 2018, In : Chemical and Pharmaceutical Bulletin. 66, 11, p. 1048-1056 9 p.

Research output: Contribution to journalArticle

Drying
Hot Temperature
Heat transfer
Temperature
Air
2017
2 Citations (Scopus)

A label-free fluorescent array sensor utilizing liposome encapsulating calcein for discriminating target proteins by principal component analysis

Imamura, R., Murata, N., Shimanouchi, T., Yamashita, K., Fukuzawa, M. & Noda, M., Jul 14 2017, In : Sensors (Switzerland). 17, 7, 1630.

Research output: Contribution to journalArticle

encapsulating
Liposomes
Sensor arrays
principal components analysis
Principal Component Analysis

Calcein leakage behavior from vesicles induced by proteinvesicle interaction: A study by surface pressurearea isotherms

Fukuma, S., Shimanouchi, T., Hayashi, K. & Kimura, Y., 2017, In : Chemistry Letters. 46, 7, p. 1036-1039 4 p.

Research output: Contribution to journalArticle

Isotherms
Substrates
Biosensors
Membrane Proteins
fluorexon

Effect of wet and dry torrefaction process on fuel properties of solid fuels derived from bamboo and Japanese cedar

Yang, W., Wu, S., Wang, H., Ma, P., Shimanouchi, T., Kimura, Y. & Zhou, J., 2017, In : BioResources. 12, 4, p. 8629-8640 12 p.

Research output: Contribution to journalArticle

Bamboo
bamboo
Cellulose
cellulose
Biomass
4 Citations (Scopus)

Tailor-made drug carrier: Comparison of formation-dependent physicochemical properties within self-assembled aggregates for an optimal drug carrier

Hayashi, K., Iwai, H., Kamei, T., Iwamoto, K., Shimanouchi, T., Fujita, S., Nakamura, H. & Umakoshi, H., Apr 1 2017, In : Colloids and Surfaces B: Biointerfaces. 152, p. 269-276 8 p.

Research output: Contribution to journalArticle

Drug Carriers
drugs
Micelles
micelles
Databases
2016
17 Citations (Scopus)

Chemical conversion and liquid-liquid extraction of 5-hydroxymethylfurfural from fructose by slug flow microreactor

Shimanouchi, T., Kataoka, Y., Tanifuji, T., Kimura, Y., Fujioka, S. & Terasaka, K., 2016, (Accepted/In press) In : AICHE Journal.

Research output: Contribution to journalArticle

Liquid-Liquid Extraction
Fructose
Gastropoda
Ketones
Liquids

Detection of Fibrillization Process of Amyloid Beta Protein Using Arrayed Biosensor with Liposome Encapsulating Fluorescent Molecules

Imamura, R., Shimanouchi, T., Murata, N., Yamashita, K., Fukuzawa, M. & Noda, M., 2016, In : Procedia Engineering. 168, p. 1414-1417 4 p.

Research output: Contribution to journalArticle

Liposomes
Biosensors
Proteins
Molecules
Phospholipids

The structural evaluation of amyloid beta on lipid membranes

Aoyagi, S., Iwamura, M., Shimanouchi, T., Yokoyama, Y. & Iwai, H., 2016, (Accepted/In press) In : Surface and Interface Analysis.

Research output: Contribution to journalArticle

Membrane Lipids
Amyloid
lipids
membranes
Secondary ion mass spectrometry
2015
9 Citations (Scopus)

Amyloidogenic mutation promotes fibril formation of the N-terminal apolipoprotein A-I on lipid membranes

Mizuguchi, C., Ogata, F., Mikawa, S., Tsuji, K., Baba, T., Shigenaga, A., Shimanouchi, T., Okuhira, K., Otaka, A. & Saito, H., Aug 21 2015, In : Journal of Biological Chemistry. 290, 34, p. 20947-20959 13 p.

Research output: Contribution to journalArticle

Apolipoprotein A-I
Membrane Lipids
Mutation
Lipids
Amyloid
3 Citations (Scopus)

Characterization of hydrochar prepared from hydrothermal carbonization of peels of Carya cathayensis sarg

Yang, W., Shimanouchi, T. & Kimura, Y., Mar 6 2015, In : Desalination and Water Treatment. 53, 10, p. 2831-2838 8 p.

Research output: Contribution to journalArticle

Carbonization
acetone
Acetone
ethanol
Ethanol
18 Citations (Scopus)
nut
Carbonization
Acetone
Heating
liquid
31 Citations (Scopus)

Elevating the fuel properties of Humulus lupulus, Plumeria alba and Calophyllum inophyllum L. through wet torrefaction

Yang, W., Shimanouchi, T., Iwamura, M., Takahashi, Y., Mano, R., Takashima, K., Tanifuji, T. & Kimura, Y., Apr 15 2015, In : Fuel. 146, p. 88-94 7 p.

Research output: Contribution to journalArticle

Biomass
Coal
Lignite
Lignin
Heating
7 Citations (Scopus)

Formation of lens-like vesicles induced via microphase separations on a sorbitan monoester membrane with different headgroups

Hayashi, K., Iwai, H., Shimanouchi, T., Umakoshi, H., Iwasaki, T., Kato, A. & Nakamura, H., Nov 1 2015, In : Colloids and Surfaces B: Biointerfaces. 135, p. 235-242 8 p.

Research output: Contribution to journalArticle

Microphase separation
Lenses
Polyethylene glycols
lenses
membranes
3 Citations (Scopus)
Lignin
Cellulose
Surface properties
Water
Contact angle

Target protein discrimination based on array sensor using calcein-encapsulating liposomes with cholesterol by principal component analysis

Imamura, R., Zhang, Z., Yoshikawa, T., Shimanouchi, T., Murata, N., Yamashita, K., Fukuzawa, M. & Noda, M., 2015, In : Procedia Engineering. 120, p. 699-702 4 p.

Research output: Contribution to journalArticle

Liposomes
Cholesterol
Sensor arrays
Principal component analysis
Fluorescence
8 Citations (Scopus)

ToF-SIMS observation for evaluating the interaction between amyloid β and lipid membranes

Aoyagi, S., Shimanouchi, T., Kawashima, T. & Iwai, H., Mar 22 2015, In : Analytical and Bioanalytical Chemistry. 407, 10, p. 2859-2863 5 p., 8527.

Research output: Contribution to journalArticle

Secondary Ion Mass Spectrometry
Membrane Lipids
Secondary ion mass spectrometry
Amyloid
Observation
2014
1 Citation (Scopus)

Comparison of the interfacial properties of span 80 vesicle, w/o emulsions and liposomes

Hayashi, K., Umakoshi, H. & Shimanouchi, T., 2014, In : Solvent Extraction Research and Development. 21, 2, p. 191-199 9 p.

Research output: Contribution to journalArticle

Emulsification
Liposomes
Emulsions
Water
Hexanes
4 Citations (Scopus)

Development of metal affinity-immobilized liposome chromatography and its basic characteristics

Nagami, H., Umakoshi, H., Kitaura, T., Thompson, G. L., Shimanouchi, T. & Kuboi, R., Mar 15 2014, In : Biochemical Engineering Journal. 84, p. 66-73 8 p.

Research output: Contribution to journalArticle

Liposomes
Chromatography
Metals
Peptides
Affinity chromatography
5 Citations (Scopus)
Sugars
Scavenging
Bioethanol
Water
Proteins
10 Citations (Scopus)

Investigation of the degradation kinetic parameters and structure changes of microcrystalline cellulose in subcritical water

Yang, W., Shimanouchi, T., Wu, S. & Kimura, Y., Nov 20 2014, In : Energy and Fuels. 28, 11, p. 6974-6980 7 p.

Research output: Contribution to journalArticle

Kinetic parameters
Cellulose
Degradation
Water
Temperature
10 Citations (Scopus)

Rapid conversion of glycerol to lactic acid under alkaline hydrothermal conditions, by using a continuous flow reaction system

Shimanouchi, T., Ueno, S., Shidahara, K. & Kimura, Y., 2014, In : Chemistry Letters. 43, 4, p. 535-537 3 p.

Research output: Contribution to journalArticle

Glycerol
Lactic Acid
Temperature
8 Citations (Scopus)

Relationship between the mobility of phosphocholine headgroup and the protein-liposome interaction: A dielectric spectroscopic study

Shimanouchi, T., Yoshimoto, N., Hiroiwa, A., Nishiyama, K., Hayashi, K. & Umakoshi, H., Apr 1 2014, In : Colloids and Surfaces B: Biointerfaces. 116, p. 343-350 8 p.

Research output: Contribution to journalArticle

Phosphorylcholine
Liposomes
proteins
Proteins
lipids
2 Citations (Scopus)

Subcritical water-assisted emulsification of decane/water: Influence of surfactants

Shimanouchi, T., Tange, T. & Kimura, Y., 2014, In : Solvent Extraction Research and Development. 21, 1, p. 103-110 8 p.

Research output: Contribution to journalArticle

Emulsification
Emulsions
Surface-Active Agents
Oils
Surface active agents
Emulsification
Surface-Active Agents
Organic solvents
Oils
Surface active agents
27 Citations (Scopus)

Systematical characterization of phase behaviors and membrane properties of fatty acid/didecyldimethylammonium bromide vesicles

Suga, K., Yokoi, T., Kondo, D., Hayashi, K., Morita, S., Okamoto, Y., Shimanouchi, T. & Umakoshi, H., Nov 4 2014, In : Langmuir. 30, 43, p. 12721-12728 8 p.

Research output: Contribution to journalArticle

fatty acids
Phase behavior
Fatty acids
bromides
Fatty Acids
5 Citations (Scopus)

Water / Methyl isobutyl ketone (MIBK) biphasic system in slug flow under high temperature and pressure conditions

Shimanouchi, T., Tanifuji, T., Fujioka, S., Terasaka, K. & Kimura, Y., 2014, In : Solvent Extraction Research and Development. 21, 2, p. 201-209 9 p.

Research output: Contribution to journalArticle

Ketones
Water
Substrates
Amino acids
Temperature
2013
7 Citations (Scopus)

Effect of liposome membranes on disaggregation of amyloid β fibrils by dopamine

Vu, H. T., Shimanouchi, T., Ishikawa, D., Matsumoto, T., Yagi, H., Goto, Y., Umakoshi, H. & Kuboi, R., Feb 5 2013, In : Biochemical Engineering Journal. 71, p. 118-126 9 p.

Research output: Contribution to journalArticle

Liposomes
Amyloid
Dopamine
Membranes
Quinine
10 Citations (Scopus)

Enhanced cytotoxicity for colon 26 cells using doxorubicin-loaded sorbitan monooleate (Span 80) vesicles

Hayashi, K., Tatsui, T., Shimanouchi, T. & Umakoshi, H., Jan 17 2013, In : International Journal of Biological Sciences. 9, 2, p. 142-148 7 p.

Research output: Contribution to journalArticle

doxorubicin
lipid bodies
vesicle
Liposomes
Doxorubicin
5 Citations (Scopus)

Growth behavior of Aβ protofibrils on liposome membranes and their membrane perturbation effect

Shimanouchi, T., Nishiyama, K., Hiroiwa, A., Vu, H. T., Kitaura, N., Umakoshi, H. & Kuboi, R., Feb 5 2013, In : Biochemical Engineering Journal. 71, p. 81-88 8 p.

Research output: Contribution to journalArticle

Liposomes
Membranes
Hydrophobicity
Membrane Lipids
Growth
6 Citations (Scopus)

Growth behavior of giant vesicles using the electroformation method: Effect of proteins on swelling and deformation

Shimanouchi, T., Umakoshi, H. & Kuboi, R., Mar 15 2013, In : Journal of Colloid and Interface Science. 394, 1, p. 269-276 8 p.

Research output: Contribution to journalArticle

Membrane Lipids
Swelling
Proteins
Phospholipids
Ionic strength
7 Citations (Scopus)

Membrane fusion mediated by phospholipase C under endosomal pH conditions

Shimanouchi, T., Kawasaki, H., Fuse, M., Umakoshi, H. & Kuboi, R., Mar 1 2013, In : Colloids and Surfaces B: Biointerfaces. 103, p. 75-83 9 p.

Research output: Contribution to journalArticle

Membrane Fusion
Type C Phospholipases
Fusion reactions
fusion
membranes
13 Citations (Scopus)
Liposomes
Phospholipids
membranes
Membranes
interactions
11 Citations (Scopus)
Fructose
Ketones
Oils
Water
Decomposition
2012
3 Citations (Scopus)

Effect of copper (II) ion against elongation behavior of amyloid β fibrils on liposome membranes

Shimanouchi, T., Onishi, R., Kitaura, N., Umakoshi, H. & Kuboi, R., Jan 2012, In : Crystal Research and Technology. 47, 1, p. 101-108 8 p.

Research output: Contribution to journalArticle

Liposomes
Amyloid
elongation
Copper
Elongation
3 Citations (Scopus)

Formation of spherulitic amyloid β aggregate by anionic liposomes

Shimanouchi, T., Shimauchi, N., Ohnishi, R., Kitaura, N., Yagi, H., Goto, Y., Umakoshi, H. & Kuboi, R., Sep 21 2012, In : Biochemical and Biophysical Research Communications. 426, 2, p. 165-171 7 p.

Research output: Contribution to journalArticle

Amyloid
Liposomes
Amyloid Plaques
Seed
Seeds
4 Citations (Scopus)

Secondary nucleation of Aβ fibrils on liposome membrane

Shimanouchi, T., Kitaura, N., Onishi, R., Umakoshi, H. & Kuboi, R., Dec 2012, In : AICHE Journal. 58, 12, p. 3625-3632 8 p.

Research output: Contribution to journalArticle

Liposomes
Amyloid
Alzheimer Disease
Nucleation
Membranes
2011
22 Citations (Scopus)

Conformational change of single-stranded RNAs induced by liposome binding

Suga, K., Tanabe, T., Tomita, H., Shimanouchi, T. & Umakoshi, H., Nov 2011, In : Nucleic acids research.. 39, 20, p. 8891-8900 10 p.

Research output: Contribution to journalArticle

Liposomes
Transfer RNA
RNA
Propane
Spectrum Analysis
8 Citations (Scopus)

Copper-mediated growth of amyloid β fibrils in the presence of oxidized and negatively charged liposomes

Shimanouchi, T., Onishi, R., Kitaura, N., Umakoshi, H. & Kuboi, R., Dec 2011, In : Journal of Bioscience and Bioengineering. 112, 6, p. 611-615 5 p.

Research output: Contribution to journalArticle

Liposomes
Amyloid
Copper
Serum Amyloid A Protein
Growth
5 Citations (Scopus)

Oxidative stress can affect the gene silencing effect of DOTAP liposome in an In Vitro translation system

Umakoshi, H., Tanabe, T., Suga, K., Bui, H. T., Shimanouchi, T. & Kuboi, R., 2011, In : International Journal of Biological Sciences. 7, 3, p. 253-260 8 p.

Research output: Contribution to journalArticle

Propane
propane
Gene Silencing
gene silencing
Ammonium Compounds
26 Citations (Scopus)

Relationship between the mobility of phosphocholine headgroups of liposomes and the hydrophobicity at the membrane interface: A characterization with spectrophotometric measurements

Shimanouchi, T., Sasaki, M., Hiroiwa, A., Yoshimoto, N., Miyagawa, K., Umakoshi, H. & Kuboi, R., Nov 1 2011, In : Colloids and Surfaces B: Biointerfaces. 88, 1, p. 221-230 10 p.

Research output: Contribution to journalArticle

Phosphorylcholine
Liposomes
Phospholipids
Hydrophobicity
Membrane Lipids
3 Citations (Scopus)

Sensitivity enhancement of leakage current microsensor for detection of target protein by using protein denaturant

Noda, M., Lorchirachoonkul, P., Shimanouchi, T., Yamashita, K., Umakoshi, H. & Kuboi, R., 2011, In : IEEE Sensors Journal. 11, 11, p. 2749-2755 7 p., 5871996.

Research output: Contribution to journalArticle

Microsensors
Leakage currents
leakage
proteins
Proteins