• 926 Citations
  • 16 h-Index
1993 …2020

Research output per year

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Research Output

  • 926 Citations
  • 16 h-Index
  • 65 Article
  • 1 Review article
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Article
2020

Channel-pore cation selectivity is a major determinant of Bacillus thuringiensis Cry46Ab mosquitocidal activity

Hayakawa, T., Miyazaki, M., Harada, S., Asakura, M. & Ide, T., Oct 1 2020, In : Applied Microbiology and Biotechnology. 104, 20, p. 8789-8799 11 p.

Research output: Contribution to journalArticle

2019

Characterization of the channel-pores formed by Bacillus thuringiensis Cry46Ab toxin in planar lipid bilayers

Sakakibara, A., Takebe, S., Ide, T. & Hayakawa, T., Nov 1 2019, In : Applied Entomology and Zoology. 54, 4, p. 389-398 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2018

Glucose, some amino acids and a plant secondary metabolite, chlorogenic acid induce the secretion of a regulatory hormone, tachykinin-related peptide, from the silkworm midgut

Yamagishi, T., Endo, H., Fukumura, K., Nagata, S., Hayakawa, T., Adegawa, S., Kasubuchi, M. & Sato, R., Aug 1 2018, In : Peptides. 106, p. 21-27 7 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Potency of the mosquitocidal Cry46Ab toxin produced using a 4AaCter-tag, which facilitates formation of protein inclusion bodies in Escherichia coli

Okazaki, T., Ichinose, J., Takebe, S., Ide, T. & Hayakawa, T., Feb 1 2018, In : Applied Entomology and Zoology. 53, 1, p. 67-73 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2017

Bacillus thuringiensis Cry11Ba works synergistically with Cry4Aa but not with Cry11Aa for toxicity against mosquito Culex pipiens (Diptera: Culicidae) larvae

Hayakawa, T., Yoneda, N., Okada, K., Higaki, A., Howlader, M. T. H. & Ide, T., Feb 1 2017, In : Applied Entomology and Zoology. 52, 1, p. 61-68 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Cry46Ab from Bacillus thuringiensis TK-E6 is a new mosquitocidal toxin with aerolysin-type architecture

Hayakawa, T., Sakakibara, A., Ueda, S., Azuma, Y., Ide, T. & Takebe, S., Aug 1 2017, In : Insect Biochemistry and Molecular Biology. 87, p. 100-106 7 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2014

Potency of insect-specific scorpion toxins on mosquito control using Bacillus thuringiensis Cry4Aa

Matsumoto, R., Shimizu, Y., Howlader, M. T. H., Namba, M., Iwamoto, A., Sakai, H. & Hayakawa, T., Jun 2014, In : Journal of Bioscience and Bioengineering. 117, 6, p. 680-683 4 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2013

Efficient production of recombinant cystatin C using a peptide-tag, 4AaCter, that facilitates formation of insoluble protein inclusion bodies in Escherichia coli

Hayashi, M., Iwamoto, S., Sato, S., Sudo, S., Takagi, M., Sakai, H. & Hayakawa, T., Mar 11 2013, In : Protein Expression and Purification. 88, 2, p. 230-234 5 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Parasporin 1Ac2, a novel cytotoxic crystal protein isolated from Bacillus thuringiensis B0462 strain

Kuroda, S., Begum, A., Saga, M., Hirao, A., Mizuki, E., Sakai, H. & Hayakawa, T., May 2013, In : Current Microbiology. 66, 5, p. 475-480 6 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2011

Mutational analyses of cry protein block7 polypeptides that facilitate the formation of protein inclusion in Escherichia coli

Hayakawa, T., Shimizu, Y., Ishida, T. & Sakai, H., Jun 1 2011, In : Applied Microbiology and Biotechnology. 90, 6, p. 1943-1951 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2010

Alanine scanning analyses of the three major loops in domain II of Bacillus thuringiensis mosquitocidal toxin cry4Aa

Howlader, M. T. H., Kagawa, Y., Miyakawa, A., Yamamoto, A., Taniguchi, T., Hayakawa, T. & Sakai, H., Feb 2010, In : Applied and environmental microbiology. 76, 3, p. 860-865 6 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Novel strategy for protein production using a peptide tag derived from Bacillus thuringiensis Cry4Aa

Hayakawa, T., Sato, S., Iwamoto, S., Sudo, S., Sakamoto, Y., Yamashita, T., Uchida, M., Matsushima, K., Kashino, Y. & Sakai, H., Jul 1 2010, In : FEBS Journal. 277, 13, p. 2883-2891 9 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2009

Biological properties of loop-replaced mutants of Bacillus thuringiensis mosquitocidal Cry4Aa

Howlader, M. T. H., Kagawa, Y., Sakai, H. & Hayakawa, T., Sep 1 2009, In : Journal of Bioscience and Bioengineering. 108, 3, p. 179-183 5 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Cry蛋白質クリスタル化機構の解析と大量発現系への応用

Hayakawa, T., 2009, In : 倉田奨励金研究報告. 39, p. 76-78 3 p.

Research output: Contribution to journalArticle

2008

Design and construction of a synthetic Bacillus thuringiensis Cry4Aa gene: Hyperexpression in Escherichia coli

Hayakawa, T., Howlader, M. T. H., Yamagiwa, M. & Sakai, H., Oct 1 2008, In : Applied Microbiology and Biotechnology. 80, 6, p. 1033-1037 5 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2007

Binding of Bacillus thuringiensis Cry1A toxins to brush border membrane vesicles of midgut from Cry1Ac susceptible and resistant Plutella xylostella

Higuchi, M., Haginoya, K., Yamazaki, T., Miyamoto, K., Katagiri, T., Tomimoto, K., Shitomi, Y., Hayakawa, T., Sato, R. & Hori, H., Aug 2007, In : Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology. 147, 4, p. 716-724 9 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Flexibility and strictness in functional replacement of domain III of cry insecticidal proteins from Bacillus thuringiensis

Sakai, H., Howlader, M. T. H., Ishida, Y., Nakaguchi, A., Oka, K., Ohbayashi, K., Yamagiwa, M. & Hayakawa, T., Apr 1 2007, In : Journal of Bioscience and Bioengineering. 103, 4, p. 381-383 3 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Histochemical analysis of Bacillus thuringiensis CrylA toxin binding to midgut epithelial cells of Bombyx mori

Hossain, D. M., Hayakawa, T., Shitomi, Y., Itoh, K., Mitsui, T., Sato, R. & Hori, H., Jan 1 2007, In : Pesticide Biochemistry and Physiology. 87, 1, p. 30-38 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Parasporin-2Ab, a newly isolated cytotoxic crystal protein from Bacillus thuringiensis

Hayakawa, T., Kanagawa, R., Kotani, Y., Kimura, M., Yamagiwa, M., Yamane, Y., Takebe, S. & Sakai, H., Oct 1 2007, In : Current Microbiology. 55, 4, p. 278-283 6 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)
2006

A novel 96-kDa aminopeptidase localized on epithelial cell membranes of Bombyx mori midgut, which binds to Cry1Ac toxin of Bacillus thuringiensis

Shitomi, Y., Hayakawa, T., Hossain, D. M., Higuchi, M., Miyamoto, K., Nakanishi, K., Sato, R. & Hori, H., Feb 1 2006, In : Journal of biochemistry. 139, 2, p. 223-233 11 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Bacillus thuringiensis Cry1Ab, but not Cry1Aa or Cry1Ac, disrupts liposomes

Kato, T., Higuchi, M., Endo, R., Maruyama, T., Haginoya, K., Shitomi, Y., Hayakawa, T., Mitsui, T., Sato, R. & Hori, H., Jan 1 2006, In : Pesticide Biochemistry and Physiology. 84, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
17 Citations (Scopus)

Localization of a novel 252-kDa plasma membrane protein that binds Cry1A toxins in the midgut epithelia of Bombyx mori

Hossain, D. M., Shitomi, Y., Nanjo, Y., Takano, D., Nishiumi, T., Hayakawa, T., Mitsui, T., Sato, R. & Hori, H., Feb 1 2005, In : Applied Entomology and Zoology. 40, 1, p. 125-135 11 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2004

Characterization of a novel plasma membrane protein, expressed in the midgut epithelia of Bombyx mori, that binds to Cry1A toxins

Hossain, D. M., Shitomi, Y., Moriyama, K., Higuchi, M., Hayakawa, T., Mitsui, T., Sato, R. & Hori, H., Aug 1 2004, In : Applied and environmental microbiology. 70, 8, p. 4604-4612 9 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

GalNAc pretreatment inhibits trapping of Bacillus thuringiensis Cry1Ac on the peritrophic membrane of Bombyx mori

Hayakawa, T., Shitomi, Y., Miyamoto, K. & Hori, H., Oct 22 2004, In : FEBS Letters. 576, 3, p. 331-335 5 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

Transgenic tobacco transformed with the Trichopusia ni granulovirus Enhancin gene affects insect development

Hayakawa, T., Hashimoto, Y., Mori, M., Kaido, M., Shimojo, E., Furusawa, I. & Granados, R. R., Mar 1 2004, In : Biocontrol Science and Technology. 14, 2, p. 211-214 4 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Increase in Indole 3-acetic Acid (IAA) level and Nitrilase Activity in Turnips Induced by Plasmodiophora brassicae Infection

Ugajin, T., Takita, K., Takahashi, H., Mitsui, T., Hayakawa, T., Hori, H., Muraoka, S., Tada, T. & Ohyama, T., 2003, In : Plant Biotechnology. 20, 3, p. 215-220 6 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Tandem repetition of baculovirus ie1 promoter results in upregulation of transcription

Kojima, K., Hayakawa, T., Asano, S. & Bando, H., Aug 14 2001, In : Archives of Virology. 146, 7, p. 1407-1414 8 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
2000

Analysis of proteins encoded in the bipartite genome of a new type of parvo-like virus isolated from silkworm - Structural protein with DNA polymerase motif

Hayakawa, T., Kojima, K., Nonaka, K., Nakagaki, M., Sahara, K., Asano, S. I., Iizuka, T. & Bando, H., Jan 1 2000, In : Virus research. 66, 1, p. 101-108 8 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Enhancement of baculovirus infection in Spodoptera exigua (Lepidoptera: Noctuidae) larvae with Autographa californica nucleopolyhedrovirus or Nicotiana tabacum engineered with a granulovirus enhancin gene

Hayakawa, T., Shimojo, E. I., Mori, M., Kaido, M., Furusawa, I., Miyata, S., Sano, Y., Matsumoto, T., Hashimoto, Y. & Granados, R. R., Feb 2000, In : Applied Entomology and Zoology. 35, 1, p. 163-170 8 p.

Research output: Contribution to journalArticle

Open Access
21 Citations (Scopus)

Patterns of genome organization and content in lepidopteran baculoviruses

Hayakawa, T., Rohrmann, G. F. & Hashimoto, Y., Dec 5 2000, In : Virology. 278, 1, p. 1-12 12 p.

Research output: Contribution to journalArticle

95 Citations (Scopus)

Physical map of a Plutella xylostella granulovirus genome

Hashimoto, Y., Hayashi, K., Hayakawa, T., Ueno, Y., Shimojo, E. I., Kondo, A., Miyasono, M., Sano, Y., Matsumoto, T. & Granados, R. R., Feb 2000, In : Applied Entomology and Zoology. 35, 1, p. 45-51 7 p.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

Sequence analysis of the Plutella xylostella granulovirus genome

Hashimoto, Y., Hayakawa, T., Ueno, Y., Fujita, T., Sano, Y. & Matsumoto, T., Sep 30 2000, In : Virology. 275, 2, p. 358-372 15 p.

Research output: Contribution to journalArticle

125 Citations (Scopus)