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Research Output 1988 2019

  • 687 Citations
  • 16 h-Index
  • 68 Article
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Article
2019

Effects of dexamethasone to reverse decreased hepatic midazolam metabolism in rats with acute renal failure

Doi, M., Kajikawa, N. & Aiba, T., Jan 1 2019, (Accepted/In press) In : Xenobiotica.

Research output: Contribution to journalArticle

Midazolam
Acute Kidney Injury
Metabolism
Dexamethasone
Rats

In vivo study on mechanism underlying increased pharmacological effects of phenobarbital in rats with glycerol-induced acute renal failure

Okada, A., Suzuki, K., Hara, K., Kojina, M. & Aiba, T., Jan 1 2019, In : Biological and Pharmaceutical Bulletin. 42, 3, p. 501-506 6 p.

Research output: Contribution to journalArticle

Open Access
Phenobarbital
Acute Kidney Injury
Glycerol
Pharmacology
GABA-A Receptors
2017
2 Citations (Scopus)

Altered hepatic drug-metabolizing activity in rats suffering from hypoxemia with experimentally induced acute lung impairment

Hori, Y., Shimizu, Y. & Aiba, T., Jul 25 2017, (Accepted/In press) In : Xenobiotica. p. 1-8 8 p.

Research output: Contribution to journalArticle

Rats
Lung
Liver
Cytochrome P-450 CYP3A
Pharmaceutical Preparations
4 Citations (Scopus)

Bortezomib combined with standard induction chemotherapy in Japanese children with refractory acute lymphoblastic leukemia

Iguchi, A., Cho, Y., Sugiyama, M., Terashita, Y., Ariga, T., Hosoya, Y., Hirabayashi, S., Manabe, A., Hara, K., Aiba, T., Shiokawa, T., Tada, H. & Sato, N., Apr 11 2017, (Accepted/In press) In : International Journal of Hematology. p. 1-8 8 p.

Research output: Contribution to journalArticle

Induction Chemotherapy
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Pediatrics
Safety
Bortezomib
Bipolar Disorder
Prospective Studies
Serum
Valproic Acid
lamotrigine

Similarities of water-soluble vitamin components among non-prescription pharmaceutical vitamin products generally available on the domestic market

Suzuki, K., Kojina, M. & Aiba, T., 2017, In : Yakugaku Zasshi. 137, 5, p. 595-602 8 p.

Research output: Contribution to journalArticle

Nonprescription Drugs
Vitamins
Water
Pharmaceutical Preparations
Riboflavin
2015
11 Citations (Scopus)
Chitosan
Vitamin B 12
Biological Availability
Gastrectomy
Anemia
2014
5 Citations (Scopus)

Effect of carrageenan-induced acute peripheral inflammation on the pharmacokinetics and hepatic metabolism of midazolam in rats

Kajikawa, N., Doi, M., Kusaba, J. I. & Aiba, T., 2014, In : Drug Metabolism and Pharmacokinetics. 29, 5, p. 400-406 7 p.

Research output: Contribution to journalArticle

Carrageenan
Midazolam
Pharmacokinetics
Inflammation
Liver
1 Citation (Scopus)
Ascitic Fluid
Peritoneal Dialysis
Pharmacokinetics
Drug Therapy
Acute Kidney Injury
2 Citations (Scopus)
Retinoid X Receptors
Niacin
Liver Microsomes
Metabolism
Skeleton
7 Citations (Scopus)

Pharmaceutical properties of a low-substituted hydroxypropyl cellulose (L-HPC) hydrogel as a novel external dressing

Ogawa, A., Nakayama, S., Uehara, M., Mori, Y., Takahashi, M., Aiba, T. & Kurosaki, Y., Dec 30 2014, In : International Journal of Pharmaceutics. 477, 1-2, p. 546-552 7 p.

Research output: Contribution to journalArticle

Hydrogel
Bandages
Pharmaceutical Preparations
Steam
Exudates and Transudates

双極性障害患者に対するラモトリギンの使用実態調査と考察

Aiba, T., 2014, In : 日本病院薬剤師会雑誌. 50, 4, p. 491-494 4 p.

Research output: Contribution to journalArticle

2013
2 Citations (Scopus)

Effect of carrageenan-induced acute peripheral inflammation on the electrolyte disposition to cerebrospinal fluid in rats

Kono, K., Okada, A., Ishikawa, A. & Aiba, T., Nov 2013, In : Biological and Pharmaceutical Bulletin. 36, 11, p. 1829-1834 6 p.

Research output: Contribution to journalArticle

Carrageenan
Electrolytes
Cerebrospinal Fluid
Lithium
Inflammation
2012
13 Citations (Scopus)

Comparative study on altered hepatic metabolism of CYP3A substrates in rats with glycerol-induced acute renal failure

Kusaba, J. I., Kajikawa, N., Kawasaki, H., Kurosaki, Y. & Aiba, T., Jan 2012, In : Biopharmaceutics and Drug Disposition. 33, 1, p. 22-29 8 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP3A
Acute Kidney Injury
Glycerol
Midazolam
Nifedipine
5 Citations (Scopus)

In vivo application of chitosan to facilitate intestinal acyclovir absorption in rats

Masuda, A., Goto, Y., Kurosaki, Y. & Aiba, T., Jul 2012, In : Journal of Pharmaceutical Sciences. 101, 7, p. 2449-2456 8 p.

Research output: Contribution to journalArticle

Acyclovir
Intestinal Absorption
Chitosan
chitosanase
Polysaccharides

The effects of body weight and combination drug therapy on the serum concentrations of zonisamide in 94 epileptic dogs: An epidemiological analysis

Fukunaga, K., Aiba, T., Saito, M., Muto, M., Watanabe, N., Uchida, K., Okuno, S., Kobayashi, T. & Orito, K., 2012, In : International Journal of Applied Research in Veterinary Medicine. 10, 3, p. 258-263 6 p.

Research output: Contribution to journalArticle

zonisamide
combination drug therapy
phenobarbital
blood serum
Combination Drug Therapy
2011
2 Citations (Scopus)
Valproic Acid
Serum
Body Weight
Body Height
Body Surface Area
3 Citations (Scopus)

Pharmacodynamic characterization of nitric oxide-mediated vasodilatory activity in isolated perfused rat mesenteric artery bed

Inoue, S., Aiba, T., Masaoka, Y., Shimizu, K., Komori, Y., Mio, M., Takatori, S., Kawasaki, H. & Kurosaki, Y., Sep 2011, In : Biological and Pharmaceutical Bulletin. 34, 9, p. 1487-1492 6 p.

Research output: Contribution to journalArticle

Mesenteric Arteries
Nitric Oxide
Vasodilation
Acetylcholine
Nitroprusside
2 Citations (Scopus)

Pharmacokinetic properties of newly synthesized retinoid X receptor agonists possessing a 6-[N-ethyl-N-(3-alkoxy-4-isopropylphenyl)amino]nicotinic acid skeleton in rats

Ogasawara, A., Murakami, Y., Yakushiji, N., Ohsawa, F., Kusaba, J. I., Aiba, T., Kurosaki, Y. & Kakuta, H., Sep 2011, In : Drug Development and Industrial Pharmacy. 37, 9, p. 1060-1067 8 p.

Research output: Contribution to journalArticle

Retinoid X Receptors
Pharmacokinetics
Niacin
Skeleton
Rats
2010
2 Citations (Scopus)

Altered electrolyte handling of the choroid plexus in rats with glycerol-induced acute renal failure

Ishikawa, A., Kono, K., Sakae, R., Aiba, T., Kawasaki, H. & Kurosaki, Y., Nov 2010, In : Biopharmaceutics and Drug Disposition. 31, 8-9, p. 455-463 9 p.

Research output: Contribution to journalArticle

Choroid Plexus
Rubidium
Acute Kidney Injury
Glycerol
Electrolytes
36 Citations (Scopus)

Population pharmacokinetic analysis of vancomycin using serum cystatin C as a marker of renal function

Tanaka, A., Aiba, T., Otsuka, T., Suemaru, K., Nishimiya, T., Inoue, T., Murase, M., Kurosaki, Y. & Araki, H., Feb 2010, In : Antimicrobial Agents and Chemotherapy. 54, 2, p. 778-782 5 p.

Research output: Contribution to journalArticle

Cystatin C
Vancomycin
Pharmacokinetics
Kidney
Serum
2009
19 Citations (Scopus)

Comparative study of increased plasma quinidine concentration in rats with glycerol- and cisplatin-induced acute renal failure

Izuwa, Y., Kusaba, J. I., Horiuchi, M., Aiba, T., Kawasaki, H. & Kurosaki, Y., 2009, In : Drug Metabolism and Pharmacokinetics. 24, 5, p. 451-457 7 p.

Research output: Contribution to journalArticle

Quinidine
Acute Kidney Injury
Glycerol
Cisplatin
Glycoproteins
3 Citations (Scopus)

Efficacy of peritoneal dialysis of tolbutamide in rats under conditions of the plasma unbound fraction being increased

Makita, T., Aiba, T., Izuwa, Y., Komori, Y., Kawasaki, H. & Kurosaki, Y., 2009, In : Biopharmaceutics and Drug Disposition. 30, 1, p. 1-8 8 p.

Research output: Contribution to journalArticle

Tolbutamide
Peritoneal Dialysis
Dialysis
Sulfadimethoxine
Sulfamethoxazole
6 Citations (Scopus)

Poor applicability of estimation method for adults to calculate unbound serum concentrations of valproic acid in epileptic neonates and infants

Ueshima, S., Aiba, T., Ishikawa, N., Sato, T., Kawasaki, H., Kurosaki, Y., Ohtsuka, Y. & Sendo, T., Aug 2009, In : Journal of Clinical Pharmacy and Therapeutics. 34, 4, p. 415-422 8 p.

Research output: Contribution to journalArticle

Valproic Acid
Newborn Infant
Serum
Drug Monitoring
Serum Albumin
2008
14 Citations (Scopus)

Characterization of non-linear relationship between total and unbound serum concentrations of valproic acid in epileptic children

Ueshima, S., Aiba, T., Makita, T., Nishihara, S., Kitamura, Y., Kurosaki, Y., Kawasaki, H., Sendo, T., Ohtsuka, Y. & Gomita, Y., Feb 2008, In : Journal of Clinical Pharmacy and Therapeutics. 33, 1, p. 31-38 8 p.

Research output: Contribution to journalArticle

Valproic Acid
Serum
Ethosuximide
Anticonvulsants
Drug Monitoring
9 Citations (Scopus)

Decreased lithium disposition to cerebrospinal fluid in rats with glycerol-induced acute renal failure

Sakae, R., Ishikawa, A., Niso, T., Komori, Y., Aiba, T., Kawasaki, H. & Kurosaki, Y., Oct 2008, In : Pharmaceutical Research. 25, 10, p. 2243-2249 7 p.

Research output: Contribution to journalArticle

Cerebrospinal fluid
Lithium
Acute Kidney Injury
Glycerol
Cerebrospinal Fluid

Frequency of decreased renal function between patients treated with brand and generic products of vancomycin hydrochloride injection

Izuwa, Y., Ueshima, S., Sato, T., Okazaki, M., Aiba, T., Kawasaki, H., Kurosaki, Y. & Sendo, T., Oct 2008, In : Yakugaku Zasshi. 128, 10, p. 1493-1498 6 p.

Research output: Contribution to journalArticle

Vancomycin
Kidney
Injections
Creatinine
Product Labeling
2007
3 Citations (Scopus)

Alteration of therapeutic efficacy of lipid microspheres incorporating prostaglandin E1 by mixing with aqueous solution

Komori, Y., Aiba, T., Kushima, M., Kawasaki, H. & Kurosaki, Y., Apr 2007, In : Journal of Pharmaceutical Sciences. 96, 4, p. 935-943 9 p.

Research output: Contribution to journalArticle

Alprostadil
Microspheres
Lipids
Sodium Chloride
Emulsions
13 Citations (Scopus)

Application of the correlation of in vitro dissolution behavior and in vivo plasma concentration profile (IVIVC) for soft-gel capsules - A pointless pursuit?

Nishimura, H., Hayashi, C., Aiba, T., Okamoto, I., Miyamoto, Y., Nakade, S., Takeda, K. & Kurosaki, Y., Nov 2007, In : Biological and Pharmaceutical Bulletin. 30, 11, p. 2221-2225 5 p.

Research output: Contribution to journalArticle

Capsules
Gels
Surface-Active Agents
Sodium Dodecyl Sulfate
Pharmaceutical Preparations
5 Citations (Scopus)

Capsaicin-induced increase of intestinal cefazolin absorption in rats.

Komori, Y., Aiba, T., Nakai, C., Sugiyama, R., Kawasaki, H. & Kurosaki, Y., Dec 2007, In : Drug Metabolism and Pharmacokinetics. 22, 6, p. 445-449 5 p.

Research output: Contribution to journalArticle

Cefazolin
Capsaicin
Intestinal Absorption
Transient Receptor Potential Channels
TRPV Cation Channels
10 Citations (Scopus)

Effects of capsaicin on intestinal cephalexin absorption in rats

Komori, Y., Aiba, T., Sugiyama, R., Nakai, C., Kawasaki, H. & Kurosaki, Y., Mar 2007, In : Biological and Pharmaceutical Bulletin. 30, 3, p. 547-551 5 p.

Research output: Contribution to journalArticle

Cephalexin
Capsaicin
Intestinal Absorption
Jejunum
Transient Receptor Potential Channels
6 Citations (Scopus)

Evaluation of intramuscular lateral distribution profile of topically administered acetaminophen in rats

Kurosaki, Y., Tagawa, M., Omoto, A., Suito, H., Komori, Y., Kawasaki, H. & Aiba, T., Oct 1 2007, In : International Journal of Pharmaceutics. 343, 1-2, p. 190-195 6 p.

Research output: Contribution to journalArticle

Acetaminophen
Muscles
Microdialysis
Pharmaceutical Preparations
2006
9 Citations (Scopus)

Peritoneal dialysis alters tolbutamide pharmacokinetics in rats with experimental acute renal failure.

Aiba, T., Horiuchi, M., Makita, T., Komori, Y., Kawasaki, H. & Kurosaki, Y., Aug 2006, In : Drug Metabolism and Pharmacokinetics. 21, 4, p. 291-296 6 p.

Research output: Contribution to journalArticle

Tolbutamide
Peritoneal Dialysis
Acute Kidney Injury
Pharmacokinetics
Protein Binding
24 Citations (Scopus)

Evaluation of phenytoin dosage regimens based on genotyping of CYP2C subfamily in routinely treated Japanese patients.

Taguchi, M., Hongou, K., Yagi, S., Miyawaki, T., Takizawa, M., Aiba, T. & Hashimoto, Y., 2005, In : Drug Metabolism and Pharmacokinetics. 20, 2, p. 107-112 6 p.

Research output: Contribution to journalArticle

Phenytoin
Pharmacokinetics
Genotype
Bayes Theorem
Genetic Polymorphisms
28 Citations (Scopus)

Intestinal expression and metabolic activity of the CYP3A subfamily in female rats

Aiba, T., Yoshinaga, M., Ishida, K., Takehara, Y. & Hashimoto, Y., Feb 2005, In : Biological and Pharmaceutical Bulletin. 28, 2, p. 311-315 5 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP3A
Rifabutin
Intestines
Testosterone
Liver
19 Citations (Scopus)

Pharmacokinetic characterization of transcellular transport and drug interaction of digoxin in Caco-2 cell monolayers

Aiba, T., Ishida, K., Yoshinaga, M., Okuno, M. & Hashimoto, Y., Jan 2005, In : Biological and Pharmaceutical Bulletin. 28, 1, p. 114-119 6 p.

Research output: Contribution to journalArticle

Transcytosis
Caco-2 Cells
Digoxin
Drug Interactions
Pharmacokinetics
34 Citations (Scopus)
Cytochrome P-450 CYP3A
Dihydroxycholecalciferols
Caco-2 Cells
Cell Line
Messenger RNA
2003
24 Citations (Scopus)

Poor correlation between intestinal and hepatic metabolic rates of CYP3A4 substrates in rats

Aiba, T., Takehara, Y., Okuno, M. & Hashimoto, Y., May 1 2003, In : Pharmaceutical Research. 20, 5, p. 745-748 4 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP3A
Metabolism
Rats
Rifabutin
Lidocaine
14 Citations (Scopus)

The increased intestinal absorption rate is responsible for the reduced hepatic first-pass extraction of propranolol in rats with cisplatin-induced renal dysfunction

Okabe, H., Mizukami, A., Taguchi, M., Aiba, T., Yasuhara, M. & Hashimoto, Y., Apr 1 2003, In : Journal of Pharmacy and Pharmacology. 55, 4, p. 479-486 8 p.

Research output: Contribution to journalArticle

Intestinal Absorption
Propranolol
Cisplatin
Acute Kidney Injury
Kidney
2001
11 Citations (Scopus)

Effect of experimental renal dysfunction on bioavailability of ajmaline in rats

Hashimoto, Y., Aiba, T., Yasuhara, M. & Hori, R., 2001, In : Journal of Pharmacy and Pharmacology. 53, 6, p. 805-813 9 p.

Research output: Contribution to journalArticle

Ajmaline
Biological Availability
Kidney
Liver
Uranyl Nitrate
1999
2 Citations (Scopus)

Application of a non-linear dispersion model to analysis of the renal handling of p-aminohippurate in isolated perfused rat kidney

Aiba, T., Kubota, S. & Koizumi, T., Jun 1999, In : Biological and Pharmaceutical Bulletin. 22, 6, p. 633-641 9 p.

Research output: Contribution to journalArticle

p-Aminohippuric Acid
Nonlinear Dynamics
Kidney
Injections
Inulin
13 Citations (Scopus)

Effect of dosage form on stereoisomeric inversion of ibuprofen in volunteers

Aiba, T., Tse, M. M., Lin, E. T. & Koizumi, T., 1999, In : Biological and Pharmaceutical Bulletin. 22, 6, p. 616-622 7 p.

Research output: Contribution to journalArticle

Ibuprofen
Dosage Forms
Volunteers
Tablets
Suspensions
3 Citations (Scopus)

Single dose pharmacokinetics and pharmacodynamics of oxazepam in normal and renal dysfunction rats

Srivastava, K., Hatanaka, T., Aiba, T., Katayama, K. & Koizumi, T., Jun 1999, In : Biological and Pharmaceutical Bulletin. 22, 6, p. 627-632 6 p.

Research output: Contribution to journalArticle

Oxazepam
Pharmacokinetics
Kidney
Benzodiazepines
Aminobutyrates
1996
30 Citations (Scopus)

A study of the hydrophilic cellulose matrix: Effect of drugs on swelling properties

Panomsuk, S. P., Hatanaka, T., Aiba, T., Katayama, K. & Koizumi, T., May 1996, In : Chemical and Pharmaceutical Bulletin. 44, 5, p. 1039-1042 4 p.

Research output: Contribution to journalArticle

Cellulose
Swelling
Polymers
Pharmaceutical Preparations
Water