• 13104 Citations
  • 61 h-Index
1983 …2019
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Research Output 1983 2019

  • 13104 Citations
  • 61 h-Index
  • 170 Article
  • 13 Review article
  • 8 Comment/debate
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Article
1996
252 Citations (Scopus)

High-efficiency in vivo gene transfer using intraarterial plasmid DNA injection following in vivo electroporation

Nishi, T., Yoshizato, K., Yamashiro, S., Takeshima, H., Sato, K., Hamada, K., Kitamura, I., Yoshimura, T., Saya, H., Kuratsu, J. I. & Ushio, Y., Mar 1 1996, In : Cancer Research. 56, 5, p. 1050-1055 6 p.

Research output: Contribution to journalArticle

Electroporation
Plasmids
Injections
Lac Operon
DNA
3 Citations (Scopus)

Increased monocyte chemoattractant protein-1 expression by tumor necrosis factor-α can mediate macrophage infiltration in gliomas

Yoshizato, K., Kuratsu, J. I., Takeshima, H., Nishi, T., Yoshimura, T. & Ushio, Y., Mar 1996, In : International Journal of Oncology. 8, 3, p. 493-497 5 p.

Research output: Contribution to journalArticle

Chemokine CCL2
Glioma
Tumor Necrosis Factor-alpha
Macrophages
Injections
85 Citations (Scopus)

Intra-alveolar Macrophage-inflammatory Peptide 2 Induces Rapid Neutrophil Localization in the Lung

Gupta, S., Feng, L., Yoshimura, T., Redick, J., Fu, S. M. & Rose, C. E., 1996, In : American Journal of Respiratory Cell and Molecular Biology. 15, 5, p. 656-663 8 p.

Research output: Contribution to journalArticle

Alveolar Macrophages
Rats
Neutrophils
Chemotactic Factors
Lipopolysaccharides
84 Citations (Scopus)

Production of monocyte chemotactic protein-1 by rat brain macrophages

Calvo, C. F., Yoshimura, T., Gelman, M. & Mallat, M., 1996, In : European Journal of Neuroscience. 8, 8, p. 1725-1734 10 p.

Research output: Contribution to journalArticle

Macrophages
Brain
Chemokines
Cell Movement
Macrophage Colony-Stimulating Factor
65 Citations (Scopus)

The cytokines NAP-1 (IL-8), MCP-1, IL-1 beta, and GRO in rabbit inflammatory skin lesions produced by the chemical irritant sulfur mustard

Tsuruta, J., Sugisaki, K., Dannenberg, A. M., Yoshimura, T., Abe, Y. & Mounts, P., 1996, In : Inflammation. 20, 3, p. 293-318 26 p.

Research output: Contribution to journalArticle

Mustard Gas
Irritants
Interleukin-8
Interleukin-1beta
Cytokines
1995
36 Citations (Scopus)

Expression of monocyte chemoattractant protein-1 in meningioma

Sato, K., Kuratsu, J. I., Takeshima, H., Yoshimura, T. & Ushio, Y., 1995, In : Journal of Neurosurgery. 82, 5, p. 874-878 5 p.

Research output: Contribution to journalArticle

Chemokine CCL2
Meningioma
Macrophages
Edema
Brain Neoplasms
49 Citations (Scopus)
Integrin alpha4beta1
Transendothelial and Transepithelial Migration
Macrophage Inflammatory Proteins
Chemokine CCL5
Chemokine CCL2
36 Citations (Scopus)
Malignant Fibrous Histiocytoma
Cell Line
Histiocytes
Macrophages
Neoplasms
162 Citations (Scopus)

Modulation of neutrophil influx in glomerulonephritis in the rat with anti-macrophage inflammatory protein-2 (MIP-2) antibody

Feng, L., Xia, Y., Yoshimura, T. & Wilson, C. B., 1995, In : Journal of Clinical Investigation. 95, 3, p. 1009-1017 9 p.

Research output: Contribution to journalArticle

Chemokine CXCL2
Glomerulonephritis
Neutrophils
Anti-Inflammatory Agents
Glomerular Basement Membrane
76 Citations (Scopus)

Neutrophil accumulation and activation by homologous IL-8 in rabbits: IL-8 Induces destruction of cartilage and production of IL-1 and IL-1 receptor antagonist in vivo

Matsukawa, A., Yoshimura, T., Maeda, T., Ohkawara, S., Takagi, K. & Yoshinaga, M., 1995, In : Journal of Immunology. 154, 10, p. 5418-5425 8 p.

Research output: Contribution to journalArticle

Neutrophil Activation
Interleukin-1 Receptors
Interleukin-8
Interleukin-1
Cartilage
46 Citations (Scopus)

Production of monocyte chemoattractant protein-1 by bovine glomerular endothelial cells

Kakizaki, Y., Waga, S., Sugimoto, K., Tanaka, H., Nukii, K., Takeya, M., Yoshimura, T. & Yokoyama, M., 1995, In : Kidney International. 48, 6, p. 1866-1874 9 p.

Research output: Contribution to journalArticle

Chemokine CCL2
Endothelial Cells
Conditioned Culture Medium
Protein Kinase Inhibitors
Messenger RNA
1994
79 Citations (Scopus)

Expression and localization of messenger RNA and protein for monocyte chemoattractant protein-1 in human malignant glioma

Takeshima, H., Kuratsu, J. I., Takeya, M., Yoshimura, T. & Ushio, Y., 1994, In : Journal of Neurosurgery. 80, 6, p. 1056-1062 7 p.

Research output: Contribution to journalArticle

Glioma
Chemokine CCL2
Messenger RNA
Proteins
Macrophages
67 Citations (Scopus)
Chemokine CCL2
Lung Injury
Macrophages
Monoclonal Antibodies
Exudates and Transudates
87 Citations (Scopus)

Macrophage-stimulating protein inhibits induction of nitric oxide production by endotoxin- or cytokine-stimulated mouse macrophages

Wang, M. H., Cox, G. W., Yoshimura, T., Sheffler, L. A., Skeel, A. & Leonard, E. J., May 13 1994, In : Journal of Biological Chemistry. 269, 19, p. 14027-14031 5 p.

Research output: Contribution to journalArticle

Macrophages
Endotoxins
Nitric Oxide
Cytokines
Lipopolysaccharides
82 Citations (Scopus)

Monocyte chemoattractant protein-1 in idiopathic pulmonary fibrosis and other interstitial lung diseases

Iyonaga, K., Takeya, M., Saita, N., Sakamoto, O., Yoshimura, T., Ando, M. & Takahashi, K., 1994, In : Human Pathology. 25, 5, p. 455-463 9 p.

Research output: Contribution to journalArticle

Idiopathic Pulmonary Fibrosis
Chemokine CCL2
Interstitial Lung Diseases
Epithelial Cells
Macrophages
48 Citations (Scopus)

Proteolytic activation of single-chain precursor macrophage-stimulating protein by nerve growth factor-γ and epidermal growth factor-binding protein, members of the kallikrein family

Wang, M. H., Gonias, S. L., Skeel, A., Wolf, B. B., Yoshimura, T. & Leonard, E. J., May 13 1994, In : Journal of Biological Chemistry. 269, 19, p. 13806-13810 5 p.

Research output: Contribution to journalArticle

Kallikreins
Macrophages
Nerve Growth Factor
Factor XIIa
Epidermal Growth Factor
31 Citations (Scopus)

Role of interleukin-1 in endotoxin-induced lung injury in the rat.

Rose, C. E., Juliano, C. A., Tracey, D. E., Yoshimura, T. & Fu, S. M., Feb 1994, In : American Journal of Respiratory Cell and Molecular Biology. 10, 2, p. 214-221 8 p.

Research output: Contribution to journalArticle

Lung Injury
Interleukin-1
Endotoxins
Rats
Interleukin-1 Receptors
115 Citations (Scopus)

Tumor-derived monocyte chemoattractant protein-1 induces intratumoral infiltration of monocyte-derived macrophage subpopulation in transplanted rat tumors

Yamashiro, S., Takeya, M., Nishi, T., Kuratsu, J. I., Yoshimura, T., Ushio, Y. & Takahashi, K., Oct 1994, In : American Journal of Pathology. 145, 4, p. 856-867 12 p.

Research output: Contribution to journalArticle

Chemokine CCL2
Macrophages
Neoplasms
Cell Line
Gliosarcoma
1993
27 Citations (Scopus)

Antibodies to macrophage stimulating protein (MSP): Specificity, epitope interactions, and immunoassay of MSP in human serum

Wang, M. H., Skeel, A., Yoshimura, T., Copeland, T. D., Sakaguchi, K. & Leonard, E. J., 1993, In : Journal of Leukocyte Biology. 54, 4, p. 289-295 7 p.

Research output: Contribution to journalArticle

Immunoassay
Epitopes
Antibodies
Serum
Kringles
59 Citations (Scopus)

cDNA cloning and expression of guinea pig neutrophil attractant protein-1 (NAP-1): NAP-1 is highly conserved in guinea pig

Yoshimura, T. & Johnson, D. G., 1993, In : Journal of Immunology. 151, 11, p. 6225-6236 12 p.

Research output: Contribution to journalArticle

Organism Cloning
Guinea Pigs
Neutrophils
Complementary DNA
Proteins
51 Citations (Scopus)

cDNA cloning of guinea pig monocyte chemoattractant protein-1 and expression of the recombinant protein

Yoshimura, T., 1993, In : Journal of Immunology. 150, 11, p. 5025-5032 8 p.

Research output: Contribution to journalArticle

Chemokine CCL2
Recombinant Proteins
Organism Cloning
Guinea Pigs
Complementary DNA
155 Citations (Scopus)
Kringles
Chromosomes, Human, Pair 3
Cloning
Chromosomes
Organism Cloning
236 Citations (Scopus)

Detection of monocyte chemoattractant protein-1 in human atherosclerotic lesions by an anti-monocyte chemoattractant protein-1 monoclonal antibody

Takeya, M., Yoshimura, T., Leonard, E. J. & Takahashi, K., 1993, In : Human Pathology. 24, 5, p. 534-539 6 p.

Research output: Contribution to journalArticle

Chemokine CCL2
Monoclonal Antibodies
Macrophages
Atherosclerotic Plaques
Endothelial Cells
114 Citations (Scopus)

Monocyte chemoattractant protein-1 (MCP-1) in inflammatory joint diseases and its involvement in the cytokine network of rheumatoid synovium

Harigai, M., Hara, M., Yoshimura, T., Leonard, E. J., Inoue, K. & Kashiwazaki, S., 1993, In : Clinical Immunology and Immunopathology. 69, 1, p. 83-91 9 p.

Research output: Contribution to journalArticle

Synovial Membrane
Joint Diseases
Chemokine CCL2
Cytokines
Synovial Fluid
73 Citations (Scopus)

Neutrophil attractant protein-1 and monocyte chemoattractant protein-1 in human serum: Effects of intravenous lipopolysaccharide on free attractants, specific IgG autoantibodies and immune complexes

Sylvester, I., Suffredini, A. F., Boujoukos, A. J., Daniel Martich, G., Danner, R. L., Yoshimura, T. & Leonard, E. J., 1993, In : Journal of Immunology. 151, 6, p. 3292-3298 7 p.

Research output: Contribution to journalArticle

Chemokine CCL2
Antigen-Antibody Complex
Autoantibodies
Lipopolysaccharides
Neutrophils
58 Citations (Scopus)

Quantitative study of monocyte chemoattractant protein-1 (MCP-1) in cerebrospinal fluid and cyst fluid from patients with malignant glioma

Kuratsu, J. I., Yoshizato, K., Yoshimura, T., Leonard, E. J., Takeshima, H. & Ushio, Y., Nov 17 1993, In : Journal of the National Cancer Institute. 85, 22, p. 1836-1839 4 p.

Research output: Contribution to journalArticle

Monocytes
Cerebrospinal fluid
Cyst Fluid
Chemokine CCL2
Glioma
25 Citations (Scopus)

Secretion of monocyte chemoattractant protein-1 (MCP-1) by human mononuclear phagocytes

Leonard, E. J., Skeel, A., Yoshimura, T. & Rankin, J., 1993, In : Advances in Experimental Medicine and Biology. 351, p. 55-64 10 p.

Research output: Contribution to journalArticle

Chemokine CCL2
Phagocytes
Tuberculin
Monocytes
Interleukin-2
1992
74 Citations (Scopus)

Neutrophil attractant protein-1-immunoglobulin G immune complexes and free anti-NAP-1 antibody in normal human serum

Sylvester, H., Yoshimura, T., Sticherling, M., Schröder, J. M., Ceska, M., Peichl, P. & Leonard, E. J., 1992, In : Journal of Clinical Investigation. 90, 2, p. 471-481 11 p.

Research output: Contribution to journalArticle

Antigen-Antibody Complex
Neutrophils
Immunoglobulin G
Antibodies
Serum
1991
43 Citations (Scopus)

Biological aspects of monocyte chemoattractant protein-1 (MCP-1)

Leonard, E. J., Skeel, A. & Yoshimura, T., 1991, In : Advances in Experimental Medicine and Biology. 305, p. 57-64 8 p.

Research output: Contribution to journalArticle

Lymphocytes
Chemokine CCL2
Chemotactic Factors
46 Citations (Scopus)

Chemotactic activity and receptor binding of neutrophil attractant/activation protein-1 (NAP-1) and structurally related host defense cytokines: Interaction of NAP-2 with the NAP-1 receptor

Leonard, E. J., Yoshimura, T., Rot, A., Noer, K., Walz, A., Baggiolini, M., Walz, D. A., Goetzl, E. J. & Castor, C. W., 1991, In : Journal of Leukocyte Biology. 49, 3, p. 258-265 8 p.

Research output: Contribution to journalArticle

Neutrophil Activation
Cytokines
Platelet Factor 4
Proteins
Neutrophils
761 Citations (Scopus)

Expression of monocyte chemoattractant protein 1 in macrophage-rich areas of human and rabbit atherosclerotic lesions

Ylä-Herttuala, S., Lipton, B. A., Rosenfeld, M. E., Särkioja, T., Yoshimura, T., Leonard, E. J., Witztum, J. L. & Steinberg, D., Jun 15 1991, In : Proceedings of the National Academy of Sciences of the United States of America. 88, 12, p. 5252-5256 5 p.

Research output: Contribution to journalArticle

Chemokine CCL2
Macrophages
Rabbits
Messenger RNA
Arteries
23 Citations (Scopus)

Human monocyte chemoattractant protein-1 (MCP-1)

Yoshimura, T. & Leonard, E. J., 1991, In : Advances in Experimental Medicine and Biology. 305, p. 47-56 10 p.

Research output: Contribution to journalArticle

Molecular Sequence Data
Chemokine CCL2
Chemotactic Factors
Cell Surface Receptors
Monocytes
150 Citations (Scopus)

Macrophage stimulating protein: Purification, partial amino acid sequence, and cellular activity

Skeel, A., Yoshimura, T., Showalter, S. D., Tanaka, S., Appella, E. & Leonard, E. J., May 1 1991, In : Journal of Experimental Medicine. 173, 5, p. 1227-1234 8 p.

Research output: Contribution to journalArticle

Amino Acid Sequence
Peritoneal Macrophages
Complement 3b Receptors
macrophage stimulating protein
Anaphylatoxin C5a Receptor
118 Citations (Scopus)
Chemokine CCL2
Cloning
Molecular Cloning
Tumor Cell Line
Rats
63 Citations (Scopus)
Neutrophil Activation
Chemokine CCL2
Organism Cloning
Spleen
Complementary DNA
90 Citations (Scopus)

Neutrophil recruitment by intradermally injected neutrophil attractant/activation protein-1

Leonard, E. J., Yoshimura, T., Tanaka, S. & Raffeld, M., May 1991, In : Journal of Investigative Dermatology. 96, 5, p. 690-694 5 p.

Research output: Contribution to journalArticle

Neutrophil Activation
Neutrophil Infiltration
Chemical activation
Proteins
Intradermal Injections
49 Citations (Scopus)

Production and characterization of mouse monoclonal antibodies against human monocyte chemoattractant protein-1

Yoshimura, T., Takeya, M., Takahashi, K., Kuratsu, J. I. & Leonard, E. J., Oct 1 1991, In : Journal of Immunology. 147, 7, p. 2229-2233 5 p.

Research output: Contribution to journalArticle

Chemokine CCL2
Monoclonal Antibodies
Enzyme-Linked Immunosorbent Assay
Proteins
Immunoprecipitation
1990
4 Citations (Scopus)

A multiwell cell settling and adherence chamber for morphology and differential counting

Leonard, E. J., Yoshimura, T. & Skeel, A., 1990, In : BioTechniques. 9, 6, p. 684-689 6 p.

Research output: Contribution to journalArticle

Monolayers
Microscopes
Fluids
Acrylics
Suspensions
115 Citations (Scopus)

Identification of high affinity receptors for human monocyte chemoattractant protein-1 on human monocytes

Yoshimura, T. & Leonard, E. J., 1990, In : Journal of Immunology. 145, 1, p. 292-297 6 p.

Research output: Contribution to journalArticle

Chemokine CCL2
Monocytes
Flow Cytometry
Lymphocytes
Biotinylation
158 Citations (Scopus)

Leukocyte specificity and binding of human neutrophil attractant/activation protein-1

Leonard, E. J., Skeel, A., Yoshimura, T., Noer, K., Kutvirt, S. & Van Epps, D., 1990, In : Journal of Immunology. 144, 4, p. 1323-1330 8 p.

Research output: Contribution to journalArticle

Neutrophil Activation
Leukocytes
Neutrophils
Proteins
Basophils
96 Citations (Scopus)
Neutrophil Activation
Zymosan
Leukotriene B4
Alveolar Macrophages
Interleukin-8
118 Citations (Scopus)

Secretion by human fibroblasts of monocyte chemoattractant protein-1, the product of gene JE

Yoshimura, T. & Leonard, E. J., 1990, In : Journal of Immunology. 144, 6, p. 2377-2383 7 p.

Research output: Contribution to journalArticle

Chemokine CCL2
Platelet-Derived Growth Factor
Fibroblasts
Genes
Glioma
1989
102 Citations (Scopus)

Complete amino acid sequence of a human monocyte chemoattractant, a putative mediator of cellular immune reactions

Robinson, E. A., Yoshimura, T., Leonard, E. J., Tanaka, S., Griffin, P. R., Shabanowitz, J., Hunt, D. F. & Appella, E., 1989, In : Proceedings of the National Academy of Sciences of the United States of America. 86, 6, p. 1850-1854 5 p.

Research output: Contribution to journalArticle

Chemotactic Factors
Monocytes
Amino Acid Sequence
Interleukin-8
Disulfides
454 Citations (Scopus)

Human monocyte chemoattractant protein-1 (MCP-1) Full-length cDNA cloning, expression in mitogen-stimulated blood mononuclear leukocytes, and sequence similarity to mouse competence gene JE

Yoshimura, T., Yuhki, N., Moore, S. K., Appella, E., Lerman, M. I. & Leonard, E. J., Feb 27 1989, In : FEBS Letters. 244, 2, p. 487-493 7 p.

Research output: Contribution to journalArticle

Mononuclear Leukocytes
Chemokine CCL2
Cloning
Mitogens
Mental Competency
20 Citations (Scopus)

Inflammatory fibrous histiocytoma presenting leukemoid reaction

Takahashi, K., Kimura, Y., Naito, M., Yoshimura, T., Uchida, H. & Araki, S., 1989, In : Pathology Research and Practice. 184, 5, p. 498-506 9 p.

Research output: Contribution to journalArticle

Leukemoid Reaction
Benign Fibrous Histiocytoma
Neoplasms
Hyperplasia
Leukocytes
75 Citations (Scopus)

Neutrophil attractant/activation protein-1 (NAP-1) causes human basophil histamine release

White, M. V., Yoshimura, T., Hook, W., Kaliner, M. A. & Leonard, E. J., 1989, In : Immunology Letters. 22, 2, p. 151-154 4 p.

Research output: Contribution to journalArticle

Neutrophil Activation
Basophils
Histamine Release
Proteins
Histamine
33 Citations (Scopus)

Production and characterization of human glioma cell-derived monocyte chemotactic factor

Kuratsu, J. I., Leonard, E. J. & Yoshimura, T., Mar 1 1989, In : Journal of the National Cancer Institute. 81, 5, p. 347-351 5 p.

Research output: Contribution to journalArticle

Monocytes
Chemotactic Factors
Glioma
Tumors
Cell
47 Citations (Scopus)

Production and characterization of recombinant human neutrophil chemotactic factor

Furuta, R., Yamagishi, J., Kotani, H., Sakamoto, F., Fukui, T., Matsui, Y., Sohmura, Y., Yamada, M., Yoshimura, T., Larsen, C. G., Oppenheim, J. J. & Matsushima, K., Sep 1989, In : Journal of Biochemistry. 106, 3, p. 436-441 6 p.

Research output: Contribution to journalArticle

Neutrophils
Polypeptides
Interleukin-8
Amino acids
Genetic engineering
379 Citations (Scopus)

Purification and amino acid analysis of two human glioma-derived monocyte chemoattractants

Yoshimura, T., Robinson, E. A., Tanaka, S., Appella, E., Kuratsu, J. I. & Leonard, E. J., 1989, In : Journal of Experimental Medicine. 169, 4, p. 1449-1459 11 p.

Research output: Contribution to journalArticle

Chemotactic Factors
Glioma
Monocytes
Amino Acids
Peptides
220 Citations (Scopus)

Purification and amino acid analysis of two human monocyte chemoattractants produced by phytohemagglutinin-stimulated human blood mononuclear leukocytes

Yoshimura, T., Robinson, E. A., Tanaka, S., Appella, E. & Leonard, E. J., 1989, In : Journal of Immunology. 142, 6, p. 1956-1962 7 p.

Research output: Contribution to journalArticle

Mononuclear Leukocytes
Chemotactic Factors
Phytohemagglutinins
Monocytes
Glioma