• 13104 Citations
  • 61 h-Index
1983 …2019
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Research Output 1983 2019

  • 13104 Citations
  • 61 h-Index
  • 170 Article
  • 13 Review article
  • 8 Comment/debate
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Article
2 Citations (Scopus)

A C5-derived macrophage chemotactic factor from DNP-ascaris extract-induced skin lesion in guinea pigs

Hirashima, M., Hirotsu, Y., Yoshimura, T. & Hayashi, H., 1983, In : International Archives of Allergy and Applied Immunology. 70, 4, p. 361-367 7 p.

Research output: Contribution to journalArticle

Ascaris
Interleukin-8
Guinea Pigs
Macrophages
Chemotactic Factors
44 Citations (Scopus)
TNF Receptor-Associated Factor 6
p38 Mitogen-Activated Protein Kinases
Dendritic Cells
Protein Kinases
Monocytes
76 Citations (Scopus)

Activation of Discoidin Domain Receptor 1 Isoform b with Collagen Up-Regulates Chemokine Production in Human Macrophages: Role of p38 Mitogen-Activated Protein Kinase and NF-κB

Matsuyama, W., Wang, L., Farrar, W. L., Faure, M. & Yoshimura, T., Feb 15 2004, In : Journal of Immunology. 172, 4, p. 2332-2340 9 p.

Research output: Contribution to journalArticle

Proto-Oncogene Proteins c-akt
p38 Mitogen-Activated Protein Kinases
Chemokines
Protein Isoforms
Up-Regulation
32 Citations (Scopus)

Activation of discoidin domain receptor 1 on CD14-positive bronchoalveolar lavage fluid cells induces chemokine production in idiopathic pulmonary fibrosis

Matsuyama, W., Watanabe, M., Shirahama, Y., Oonakahara, K. I., Higashimoto, I., Yoshimura, T., Osame, M. & Arimura, K., May 15 2005, In : Journal of Immunology. 174, 10, p. 6490-6498 9 p.

Research output: Contribution to journalArticle

Idiopathic Pulmonary Fibrosis
Bronchoalveolar Lavage Fluid
Chemokines
Matrix Metalloproteinase 9
Chronic Obstructive Pulmonary Disease
28 Citations (Scopus)

Airway inflammation induced by recombinant guinea pig tumor necrosis factor-α

White, A. M., Yoshimura, T., Smith, A. W., Westwick, J. & Watson, M. L., Sep 1997, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 273, 3 17-3

Research output: Contribution to journalArticle

Guinea Pigs
Tumor Necrosis Factor-alpha
Inflammation
Eosinophils
Eosinophilia
2 Citations (Scopus)

Airway inflammation induced by recombinant guinea pig tumor necrosis factor-α

White, A. M., Yoshimura, T., Smith, A. W., Westwick, J. & Watson, M. L., 1997, In : American Journal of Physiology - Cell Physiology. 273, 3 PART 1

Research output: Contribution to journalArticle

Guinea Pigs
Tumor Necrosis Factor-alpha
Inflammation
Eosinophils
Eosinophilia
10 Citations (Scopus)

Albumin stimulates monocyte chemotactic protein-1 expression in rat embryonic mixed brain cells

Calvo, C. F., Amigou, E., Tencé, M., Yoshimura, T. & Glowinski, J., Jun 1 2005, In : Journal of Neuroscience Research. 80, 5, p. 707-714 8 p.

Research output: Contribution to journalArticle

Chemokine CCL2
Albumins
Brain
Ovalbumin
Endopeptidase K
9 Citations (Scopus)
Neutrophils
Tumor Necrosis Factor-alpha
Chemokine CCL2
Phytohemagglutinins
Blood Cells
4 Citations (Scopus)

A multiwell cell settling and adherence chamber for morphology and differential counting

Leonard, E. J., Yoshimura, T. & Skeel, A., 1990, In : BioTechniques. 9, 6, p. 684-689 6 p.

Research output: Contribution to journalArticle

Monolayers
Microscopes
Fluids
Acrylics
Suspensions
64 Citations (Scopus)
Interleukin-1 Receptors
Uric Acid
Interleukin-8
Interleukin-1
Arthritis
78 Citations (Scopus)

Analysis of the inflammatory cytokine network among TNFα, IL-1β, IL-1 receptor antagonist, and IL-8 in LPS-induced rabbit arthritis

Matsukawa, A., Yoshimura, T., Miyamoto, K., Ohkawara, S. & Yoshinaga, M., May 1997, In : Laboratory Investigation. 76, 5, p. 629-638 10 p.

Research output: Contribution to journalArticle

Interleukin-1 Receptors
Interleukin-8
Interleukin-1
Arthritis
Lipopolysaccharides
5 Citations (Scopus)

A Novel Role of Spred2 in the Colonic Epithelial Cell Homeostasis and Inflammation

Takahashi, S., Yoshimura, T., Ohkura, T., Fujisawa, M., Fushimi, S., Ito, T., Itakura, J., Hiraoka, S., Okada, H., Yamamoto, K. & Matsukawa, A., Nov 21 2016, In : Scientific Reports. 6, 37531.

Research output: Contribution to journalArticle

Knockout Mice
Homeostasis
Epithelial Cells
Dextran Sulfate
Inflammation
27 Citations (Scopus)

Antibodies to macrophage stimulating protein (MSP): Specificity, epitope interactions, and immunoassay of MSP in human serum

Wang, M. H., Skeel, A., Yoshimura, T., Copeland, T. D., Sakaguchi, K. & Leonard, E. J., 1993, In : Journal of Leukocyte Biology. 54, 4, p. 289-295 7 p.

Research output: Contribution to journalArticle

Immunoassay
Epitopes
Antibodies
Serum
Kringles
31 Citations (Scopus)

Antibody to Mac-1 or Monocyte Chemoattractant Protein-1 Inhibits Monocyte Recruitment and Promotes Tumor Growth

Zhang, L., Yoshimura, T. & Graves, D. T., May 15 1997, In : Journal of Immunology. 158, 10, p. 4855-4861 7 p.

Research output: Contribution to journalArticle

Chemokine CCL2
Monocytes
Antibodies
Macrophages
Growth
24 Citations (Scopus)

Anti-inflammatory actions of interleukin-13: Suppression of tumor necrosis factor-α and antigen-induced leukocyte accumulation in the guinea pig lung

Watson, M. L., White, A. M., Campbell, E. M., Smith, A. W., Uddin, J., Yoshimura, T. & Westwick, J., 1999, In : American Journal of Respiratory Cell and Molecular Biology. 20, 5, p. 1007-1012 6 p.

Research output: Contribution to journalArticle

Interleukin-13
HLA Antigens
Guinea Pigs
Anti-Inflammatory Agents
Tumor Necrosis Factor-alpha
152 Citations (Scopus)

Bacterial c-di-GMP is an immunostimulatory molecule

Karaolis, D. K. R., Means, T. K., Yang, D., Takahashi, M., Yoshimura, T., Muraille, E., Philpott, D., Schroeder, J. T., Hyodo, M., Hayakawa, Y., Talbot, B. G., Brouillette, E. & Malouin, F., Feb 15 2007, In : Journal of Immunology. 178, 4, p. 2171-2181 11 p.

Research output: Contribution to journalArticle

Dendritic Cells
Staphylococcus aureus
bis(3',5')-cyclic diguanylic acid
Chemokine CCL5
Chemokine Receptors
43 Citations (Scopus)

Biological aspects of monocyte chemoattractant protein-1 (MCP-1)

Leonard, E. J., Skeel, A. & Yoshimura, T., 1991, In : Advances in Experimental Medicine and Biology. 305, p. 57-64 8 p.

Research output: Contribution to journalArticle

Lymphocytes
Chemokine CCL2
Chemotactic Factors
59 Citations (Scopus)

cDNA cloning and expression of guinea pig neutrophil attractant protein-1 (NAP-1): NAP-1 is highly conserved in guinea pig

Yoshimura, T. & Johnson, D. G., 1993, In : Journal of Immunology. 151, 11, p. 6225-6236 12 p.

Research output: Contribution to journalArticle

Organism Cloning
Guinea Pigs
Neutrophils
Complementary DNA
Proteins
51 Citations (Scopus)

cDNA cloning of guinea pig monocyte chemoattractant protein-1 and expression of the recombinant protein

Yoshimura, T., 1993, In : Journal of Immunology. 150, 11, p. 5025-5032 8 p.

Research output: Contribution to journalArticle

Chemokine CCL2
Recombinant Proteins
Organism Cloning
Guinea Pigs
Complementary DNA
36 Citations (Scopus)

Cell surface receptor FPR2 promotes antitumor host defense by limiting M2 polarization of macrophages

Liu, Y., Chen, K., Wang, C., Gong, W., Yoshimura, T., Liu, M. & Wang, J. M., Jan 15 2013, In : Cancer Research. 73, 2, p. 550-560 11 p.

Research output: Contribution to journalArticle

Cell Surface Receptors
Lewis Lung Carcinoma
Macrophages
Neoplasms
Phenotype
12 Citations (Scopus)
Genes
Transcription
Assays
CCAAT-Binding Factor
Electrophoretic mobility

Chemoattractant efficacy: Oxidation of stimulus by responding cells

Yoshimura, T., Rot, A. & Leonard, E. J., Jul 16 1986, In : Biochemical and Biophysical Research Communications. 138, 1, p. 66-71 6 p.

Research output: Contribution to journalArticle

Chemotactic Factors
Sulfur
Albumins
Neutrophils
Antioxidants
16 Citations (Scopus)

Chemokine production and adhesion molecule expression by neural cells exposed to IL-1, TNFα and interferon

Chuluyan, H. E., Lang, B. J., Yoshimura, T., Kenney, J. S. & Issekutz, A. C., Oct 16 1998, In : Life Sciences. 63, 21, p. 1939-1952 14 p.

Research output: Contribution to journalArticle

Neural Cell Adhesion Molecules
Interleukin-1
Chemokines
Vascular Cell Adhesion Molecule-1
Interferons
60 Citations (Scopus)

Chemokine production by human vascular smooth muscle cells: Modulation by IL-13

Jordan, N. J., Watson, M. L., Williams, R. J., Roach, A. G., Yoshimura, T. & Westwick, J., 1997, In : British Journal of Pharmacology. 122, 4, p. 749-757 9 p.

Research output: Contribution to journalArticle

Interleukin-13
Vascular Smooth Muscle
Chemokines
Smooth Muscle Myocytes
Interleukin-8
46 Citations (Scopus)

Chemotactic activity and receptor binding of neutrophil attractant/activation protein-1 (NAP-1) and structurally related host defense cytokines: Interaction of NAP-2 with the NAP-1 receptor

Leonard, E. J., Yoshimura, T., Rot, A., Noer, K., Walz, A., Baggiolini, M., Walz, D. A., Goetzl, E. J. & Castor, C. W., 1991, In : Journal of Leukocyte Biology. 49, 3, p. 258-265 8 p.

Research output: Contribution to journalArticle

Neutrophil Activation
Cytokines
Platelet Factor 4
Proteins
Neutrophils
7 Citations (Scopus)

Chemotactic macrophage subpopulations defined by macrophage chemotactic factors from delayed hypersensitivity reaction sites

Honda, M., Yoshimura, T., Watanabe, T. & Hayashi, H., 1983, In : Journal of Immunology. 131, 6, p. 2989-2994 6 p.

Research output: Contribution to journalArticle

Chemotactic Factors
Delayed Hypersensitivity
Macrophages
Listeria
Histocompatibility Antigens Class II
4 Citations (Scopus)
Chemotactic Factors
Delayed Hypersensitivity
Macrophages
Cell Line
Myeloid Leukemia
6 Citations (Scopus)

Chemotaxis of macrophage in inflammation

Hayashi, H., Yoshimura, T. & Jinyan, C., 1985, In : Comparative Immunology, Microbiology and Infectious Diseases. 8, 2, p. 73-87 15 p.

Research output: Contribution to journalArticle

chemoattractants
Chemotactic Factors
chemotaxis
Chemotaxis
macrophages
155 Citations (Scopus)
Kringles
Chromosomes, Human, Pair 3
Cloning
Chromosomes
Organism Cloning
15 Citations (Scopus)

Cloning and characterization of guinea pig CXCR1

Takahashi, M., Jeevan, A., Sawant, K., McMurray, D. N. & Yoshimura, T., Feb 2007, In : Molecular Immunology. 44, 5, p. 878-888 11 p.

Research output: Contribution to journalArticle

Interleukin-8
Organism Cloning
Guinea Pigs
Interleukin-8A Receptors
Clone Cells
43 Citations (Scopus)

Cloning and functional characterization of the 5'-flanking region of the human monocyte chemoattractant protein-1 receptor (CCR2) gene: Essential role of 5'-untranslated region in tissue-specific expression

Yamamoto, K., Takeshima, H., Hamada, K., Nakao, M., Kino, T., Nishi, T., Kochi, M., Kuratsu, J. I., Yoshimura, T. & Ushio, Y., Feb 19 1999, In : Journal of Biological Chemistry. 274, 8, p. 4646-4654 9 p.

Research output: Contribution to journalArticle

CCR2 Receptors
CCAAT-Enhancer-Binding Proteins
TATA Box
5' Flanking Region
Cloning
10 Citations (Scopus)

Cloning of guinea pig IL-4: Reduced IL-4 mRNA after vaccination or Mycobacterium tuberculosis infection

Jeevan, A., Yoshimura, T., Ly, L. H., Dirisala, V. R. & McMurray, D. N., Jan 2011, In : Tuberculosis. 91, 1, p. 47-56 10 p.

Research output: Contribution to journalArticle

Mycobacterium Infections
Mycobacterium tuberculosis
Interleukin-4
Organism Cloning
Guinea Pigs
102 Citations (Scopus)

Complete amino acid sequence of a human monocyte chemoattractant, a putative mediator of cellular immune reactions

Robinson, E. A., Yoshimura, T., Leonard, E. J., Tanaka, S., Griffin, P. R., Shabanowitz, J., Hunt, D. F. & Appella, E., 1989, In : Proceedings of the National Academy of Sciences of the United States of America. 86, 6, p. 1850-1854 5 p.

Research output: Contribution to journalArticle

Chemotactic Factors
Monocytes
Amino Acid Sequence
Interleukin-8
Disulfides
17 Citations (Scopus)

Crosstalk between tumor cells and macrophages in stroma renders tumor cells as the primary source of MCP-1/CCL2 in Lewis lung carcinoma

Yoshimura, T., Liu, M., Chen, X., Li, L. & Wang, J. M., 2015, In : Frontiers in Immunology. 6, JUN, 332.

Research output: Contribution to journalArticle

Lewis Lung Carcinoma
Macrophages
Neoplasms
Stromal Cells
Cell Communication
79 Citations (Scopus)

Cutting edge: A critical role for the G protein-coupled receptor mFPR2 in airway inflammation and immune responses

Chen, K., Le, Y., Liu, Y., Gong, W., Ying, G., Huang, J., Yoshimura, T., Tessarollo, L. & Wang, J. M., Apr 1 2010, In : Journal of Immunology. 184, 7, p. 3331-3335 5 p.

Research output: Contribution to journalArticle

G-Protein-Coupled Receptors
Inflammation
Bronchoalveolar Lavage Fluid
Dendritic Cells
Mucous Membrane
14 Citations (Scopus)

Cytogenetic and functional studies of leukocytes with pelger-huët anomaly

Matsumoto, T., Harada, Y., Yamaguchi, K., Matsuzaki, H., Sanada, I., Yoshimura, T., Honda, M. & Tanaka, R., 1984, In : Acta Haematologica. 72, 4, p. 264-273 10 p.

Research output: Contribution to journalArticle

Cytogenetics
Reference Values
Neutrophils
Leukocytes
Antibody-Dependent Cell Cytotoxicity
2 Citations (Scopus)

Deficiency in Fpr2 results in reduced numbers of LincKitSca1 myeloid progenitor cells

Chen, K., Singh, V. K., Tang, P., Bao, Z., He, T., Xiang, Y., Gong, W., Yoshimura, T., Le, Y., Tessarollo, L., Chen, X. & Wang, J. M., Jan 1 2018, In : Journal of Biological Chemistry. 293, 35, p. 13452-13463 12 p.

Research output: Contribution to journalArticle

Myeloid Progenitor Cells
Bone
Stem Cell Factor
Bone Marrow
Bone Marrow Cells
236 Citations (Scopus)

Detection of monocyte chemoattractant protein-1 in human atherosclerotic lesions by an anti-monocyte chemoattractant protein-1 monoclonal antibody

Takeya, M., Yoshimura, T., Leonard, E. J. & Takahashi, K., 1993, In : Human Pathology. 24, 5, p. 534-539 6 p.

Research output: Contribution to journalArticle

Chemokine CCL2
Monoclonal Antibodies
Macrophages
Atherosclerotic Plaques
Endothelial Cells
2 Citations (Scopus)

Dexamethasone suppresses concanavalin A-induced production of chemotactic lymphokines by releasing a soluble factor from splenic T lymphocytes

Hirashima, M., Sakata, K., Tashiro, K., Yoshimura, T. & Hayashi, H., 1985, In : Immunology. 54, 3, p. 533-540 8 p.

Research output: Contribution to journalArticle

Lymphokines
Concanavalin A
Dexamethasone
T-Lymphocytes
Spleen
23 Citations (Scopus)

Differential effects of protein kinase C inhibitors on chemokine production in human synovial fibroblasts

Jordan, N. J., Watson, M. L., Yoshimura, T. & Westwick, J., 1996, In : British Journal of Pharmacology. 117, 6, p. 1245-1253 9 p.

Research output: Contribution to journalArticle

Protein C Inhibitor
Protein Kinase Inhibitors
Chemokines
Protein Kinase C
Interleukin-1
27 Citations (Scopus)
Mycobacterium bovis
Mycobacterium tuberculosis
Interferon-gamma
Interferons
Guinea Pigs
46 Citations (Scopus)

Differential expression of macrophage inflammatory protein-2 and monocyte chemoattractant protein-1 in experimental glomerulonephritis

Tam, F. W. K., Karkar, A. M., Smith, J., Yoshimura, T., Steinkasserer, A., Kurrle, R., Langner, K. & Rees, A. J., 1996, In : Kidney International. 49, 3, p. 715-721 7 p.

Research output: Contribution to journalArticle

Chemokine CXCL2
Chemokine CCL2
Glomerulonephritis
Nephritis
Neutrophil Infiltration
93 Citations (Scopus)

Discoidin domain receptor 1 isoform-a (DDR1alpha) promotes migration of leukocytes in three-dimensional collagen lattices.

Kamohara, H., Yamashiro, S., Galligan, C. & Yoshimura, T., Dec 2001, In : FASEB Journal. 15, 14, p. 2724-2726 3 p.

Research output: Contribution to journalArticle

Protein Isoforms
Leukocytes
Collagen
Tissue
Integrins
53 Citations (Scopus)

Discoidin domain receptor 1 mediates collagen-induced nitric oxide production in J774A.1 murine macrophages

Kim, S. H., Lee, S., Suk, K., Bark, H., Jun, C. D., Kim, D. K., Choi, C. H. & Yoshimura, T., Feb 1 2007, In : Free Radical Biology and Medicine. 42, 3, p. 343-352 10 p.

Research output: Contribution to journalArticle

Macrophages
Nitric Oxide
Collagen
Chemical activation
p38 Mitogen-Activated Protein Kinases
26 Citations (Scopus)

Effect of Mycobacterium bovis BCG vaccination on interleukin-1β and RANTES mRNA expression in guinea pig cells exposed to attenuated and virulent mycobacteria

Jeevan, A., Yoshimura, T., Foster, G. & McMurray, D. N., 2002, In : Infection and Immunity. 70, 3, p. 1245-1253 9 p.

Research output: Contribution to journalArticle

Mycobacterium
Mycobacterium bovis
Interleukin-1
Chemokines
Guinea Pigs
25 Citations (Scopus)

Effect of Mycobacterium bovis BCG Vaccination on Mycobacterium-Specific Cellular Proliferation and Tumor Necrosis Factor Alpha Production from Distinct Guinea Pig Leukocyte Populations

Lasco, T. M., Yamamoto, T., Yoshimura, T., Allen, S. S., Cassone, L. & McMurray, D. N., Dec 2003, In : Infection and Immunity. 71, 12, p. 7035-7042 8 p.

Research output: Contribution to journalArticle

Mycobacterium
Mycobacterium bovis
Guinea Pigs
Vaccination
Leukocytes
4 Citations (Scopus)

Effects of Induction Therapy on Wound Healing at Bronchial Anastomosis Sites in Rats

Shirafuji, T., Oka, T., Sawada, T., Tamura, K., Nagayasu, T., Takeya, M., Yoshimura, T. & Ayabe, H., Jun 2003, In : Japanese Journal of Thoracic and Cardiovascular Surgery. 51, 6, p. 217-224 8 p.

Research output: Contribution to journalArticle

Wound Healing
Macrophages
Leukopenia
Therapeutics
Drug Therapy
40 Citations (Scopus)

Evaluating the role of tumor necrosis factor-alpha in experimental pulmonary tuberculosis in the guinea pig

Lasco, T. M., Cassone, L., Kamohara, H., Yoshimura, T. & McMurray, D. N., Jul 2005, In : Tuberculosis. 85, 4, p. 245-258 14 p.

Research output: Contribution to journalArticle

Pulmonary Tuberculosis
tuberculosis
guinea pigs
tumor necrosis factor-alpha
Guinea Pigs
79 Citations (Scopus)

Expression and localization of messenger RNA and protein for monocyte chemoattractant protein-1 in human malignant glioma

Takeshima, H., Kuratsu, J. I., Takeya, M., Yoshimura, T. & Ushio, Y., 1994, In : Journal of Neurosurgery. 80, 6, p. 1056-1062 7 p.

Research output: Contribution to journalArticle

Glioma
Chemokine CCL2
Messenger RNA
Proteins
Macrophages
113 Citations (Scopus)

Expression of CCR6 and CD83 by cytokine-activated human neutrophils

Yamashiro, S., Wang, J. M., Yang, D., Gong, W. H., Kamohara, H. & Yoshimura, T., Dec 1 2000, In : Blood. 96, 12, p. 3958-3963 6 p.

Research output: Contribution to journalArticle

Neutrophils
Cytokines
Tumor Necrosis Factor-alpha
Interferons
Chemical activation