• 1143 Citations
  • 22 h-Index
1990 …2019

Research output per year

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Research Output

  • 1143 Citations
  • 22 h-Index
  • 55 Article
  • 2 Comment/debate
  • 2 Review article
  • 1 Chapter
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Article
1990

Practical preparation of optically active O-benzylglycidol from optically active epichlorohydrin

Takano, S., Sekiguchi, Y., Setoh, M., Yoshimitsu, T., Inomata, K., Takahashi, M. & Ogasawara, K., Sep 1 1990, In : Heterocycles. 31, 9, p. 1715-1719 5 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)
1994

Asymmetric Dihydroxylation of a Meso-Symmetric Cyclic Diene Using AD-Mix Reagents: A New Enantiocontrolled Route to Conduritol E

Takano, S., Yoshimitsu, T. & Ogasawara, K., Jan 1 1994, In : Journal of Organic Chemistry. 59, 1, p. 54-57 4 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Enantioconvergent route to a functionalized quinane system

Yoshimitsu, T., Ohshiba, Y. & Ogasawara, K., Jan 1 1994, In : Synthesis. 10, p. 1029-1031 3 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
13 Citations (Scopus)
17 Citations (Scopus)
1995

Practical Chiral Route to Muscarine and its Three Diastereomers

Ohshiba, Y., Yoshimitsu, T. & Ogasawara, K., Jan 1 1995, In : Chemical and Pharmaceutical Bulletin. 43, 6, p. 1067-1069 3 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

The Mitsunobu Reaction of 1,2-O-Benzylideneconduritol E: A New Route to Conduritol F

Yoshimitsu, T. & Ogasawara, K., Mar 1 1995, In : Synlett. 1995, 3, p. 257-259 3 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
1996

A new synthesis of (-)-mesembrine employing sharpless AD reaction and new radical-initiated reaction

Yoshimitsu, T. & Ogasawara, K., Dec 1 1996, In : Heterocycles. 42, 1, p. 135-139 5 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)
1999

An approach to the synthesis of CP-263,114: Complementary routes to the bicyclic ring system via two kinds of fragmentation reaction

Yoshimitsu, T., Yanagiya, M. & Nagaoka, H., Jul 9 1999, In : Tetrahedron Letters. 40, 28, p. 5215-5218 4 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

A new synthetic route for construction of the core of Zaragozic acids

Koshimizu, H., Baba, T., Yoshimitsu, T. & Nagaoka, H., Apr 2 1999, In : Tetrahedron Letters. 40, 14, p. 2777-2780 4 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)
39 Citations (Scopus)
2000

Asymmetric synthesis of the core structure of (-)-CP-263,114

Yoshimitsu, T., Yanagisawa, S. & Nagaoka, H., Nov 16 2000, In : Organic Letters. 2, 23, p. 3751-3754 4 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

New route to the synthesis of the illudane skeleton by Michael-Michael- elimination reaction

Tokuzaki, K., Kanemitu, Y., Yoshimitsu, T. & Nagaoka, H., Jul 29 2000, In : Tetrahedron Letters. 41, 31, p. 5923-5926 4 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2002

Synthesis of the CD ring system of paclitaxel by atom-transfer radical annulation reaction

Yoshimitsu, T., Nakajima, H. & Nagaoka, H., Nov 18 2002, In : Tetrahedron Letters. 43, 47, p. 8587-8590 4 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
2003

Hydroxyalkylation of α-C-H bonds of tetrahydrofuran with aldehydes in the presence of triethylborane and tert-butyl hydroperoxide

Yoshimitsu, T., Arano, Y. & Nagaoka, H., Jan 24 2003, In : Journal of Organic Chemistry. 68, 2, p. 625-627 3 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

Synthesis of (-)-muricatacin via α- and α′-C-H bond functionalization of tetrahydrofuran

Yoshimitsu, T., Makino, T. & Nagaoka, H., Sep 19 2003, In : Journal of Organic Chemistry. 68, 19, p. 7548-7550 3 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)
2004

Studies on the total synthesis of (-)-CP-263,114

Yoshimitsu, T., Sasaki, S., Arano, Y. & Nagaoka, H., Dec 24 2004, In : Journal of Organic Chemistry. 69, 26, p. 9262-9268 7 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Total Synthesis of (+)-Muconin

Yoshimitsu, T., Makino, T. & Nagaoka, H., Mar 19 2004, In : Journal of Organic Chemistry. 69, 6, p. 1993-1998 6 p.

Research output: Contribution to journalArticle

49 Citations (Scopus)
2005

Radical hydroxyalkylation of C-H bond adjacent to nitrogen of tertiary amides, ureas, and amines

Yoshimitsu, T., Arano, Y. & Nagaoka, H., Aug 24 2005, In : Journal of the American Chemical Society. 127, 33, p. 11610-11611 2 p.

Research output: Contribution to journalArticle

61 Citations (Scopus)

Radical α-C-H hydroxyalkylation of ethers and acetal

Yoshimitsu, T., Arano, Y. & Nagaoka, H., Mar 18 2005, In : Journal of Organic Chemistry. 70, 6, p. 2342-2345 4 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)
2007

Radical fixation of functionalized carbon resources: α-sp 3C - H carbamoylation of tertiary amines with aryl isocyanates

Yoshimitsu, T., Matsuda, K., Nagaoka, H., Tsukamoto, K. & Tanaka, T., Nov 22 2007, In : Organic Letters. 9, 24, p. 5115-5118 4 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)
2008

Synthesis of (±)-aphanorphine: a new approach to tricyclic 3-benzazepine scaffold using two radical C-C bond-forming reactions

Yoshimitsu, T., Atsumi, C., Iimori, E., Nagaoka, H. & Tanaka, T., Jul 21 2008, In : Tetrahedron Letters. 49, 29-30, p. 4473-4475 3 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Total synthesis of (-)-agelastatin A

Yoshimitsu, T., Ino, T. & Tanaka, T., Dec 1 2008, In : Organic Letters. 10, 23, p. 5457-5460 4 p.

Research output: Contribution to journalArticle

57 Citations (Scopus)
2009

Enantiocontrolled synthesis of polychlorinated hydrocarbon motifs: A nucleophilic multiple chlorination process revisited

Yoshimitsu, T., Fukumoto, N. & Tanaka, T., Jan 16 2009, In : Journal of Organic Chemistry. 74, 2, p. 696-702 7 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)

Studies of the asymmetric total synthesis of clavilactone D by the 'lariat' cyclization strategy

Yoshimitsu, T., Nojima, S., Hashimoto, M., Tsukamoto, K. & Tanaka, T., Nov 18 2009, In : Synthesis. 17, p. 2963-2969 7 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Synthesis of chaetomellic anhydride A, A potent inhibitor of ras protein farnesyltransferase

Yoshimitsu, T., Arano, Y., Kaji, T., Ino, T., Nagaoka, H. & Tanaka, T., Jan 1 2009, In : Heterocycles. 77, 1, p. 179-186 8 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Total synthesis of the β-caten in inhibitor, (-)-agelastatin A: A second-generation approach based on radical aminobromination

Yoshimitsu, T., Ino, T., Futamura, N., Kamon, T. & Tanaka, T., Aug 6 2009, In : Organic Letters. 11, 15, p. 3402-3405 4 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)
2010

Asymmetric total synthesis of (+)-Hexachlorosulfolipid, a cytotoxin isolated from adriatic mussels

Yoshimitsu, T., Fukumoto, N., Nakatani, R., Kojima, N. & Tanaka, T., Aug 20 2010, In : Journal of Organic Chemistry. 75, 16, p. 5425-5437 13 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)

Convergent synthesis of fluorescence-labeled probes of Annonaceous acetogenins and visualization of their cell distribution

Kojima, N., Morioka, T., Urabe, D., Yano, M., Suga, Y., Maezaki, N., Ohashi-Kobayashi, A., Fujimoto, Y., Maeda, M., Yamori, T., Yoshimitsu, T. & Tanaka, T., Dec 15 2010, In : Bioorganic and Medicinal Chemistry. 18, 24, p. 8630-8641 12 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2011

Asymmetric total synthesis of (+)-danicalipin A

Yoshimitsu, T., Nakatani, R., Kobayashi, A. & Tanaka, T., Mar 4 2011, In : Organic Letters. 13, 5, p. 908-911 4 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Design and synthesis of C35-fluorinated solamins and their growth inhibitory activities against human cancer cell lines

Kojima, N., Suga, Y., Hayashi, H., Yamori, T., Yoshimitsu, T. & Tanaka, T., Oct 1 2011, In : Bioorganic and Medicinal Chemistry Letters. 21, 19, p. 5745-5749 5 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Total synthesis of (±)-kainic acid: A photochemical C-H carbamoylation approach

Kamon, T., Irifune, Y., Tanaka, T. & Yoshimitsu, T., May 20 2011, In : Organic Letters. 13, 10, p. 2674-2677 4 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Total synthesis of (±)-platencin

Yoshimitsu, T., Nojima, S., Hashimoto, M. & Tanaka, T., Jul 15 2011, In : Organic Letters. 13, 14, p. 3698-3701 4 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)
2012

Double C-H functionalization in sequential order: Direct synthesis of polycyclic compounds by a palladium-catalyzed C-H alkenylation-arylation cascade

Ohno, H., Iuchi, M., Kojima, N., Yoshimitsu, T., Fujii, N. & Tanaka, T., Apr 23 2012, In : Chemistry - A European Journal. 18, 17, p. 5352-5360 9 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Intramolecular iron(ii)-catalyzed aminobromination of allyl N-tosyloxycarbamates

Kamon, T., Shigeoka, D., Tanaka, T. & Yoshimitsu, T., Mar 28 2012, In : Organic and Biomolecular Chemistry. 10, 12, p. 2363-2365 3 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Pharmacokinetics of Agelastatin A in the central nervous system

Li, Z., Kamon, T., Personett, D. A., Caulfield, T., Copland, J. A., Yoshimitsu, T. & Tun, H. W., Feb 1 2012, In : MedChemComm. 3, 2, p. 233-237 5 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Stereoconvergent route to chiral cyclohexenone building blocks: Formal synthesis of (-)-dysidiolide

Moustafa, G. A. I., Kamada, Y., Tanaka, T. & Yoshimitsu, T., Nov 21 2012, In : Organic and Biomolecular Chemistry. 10, 43, p. 8609-8615 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Stereoselective α-quaternization of 3-methoxycycloalk-2-enones via 1,4-diastereoinduction of alkoxy dienolates

Moustafa, G. A. I., Kamada, Y., Tanaka, T. & Yoshimitsu, T., Jan 20 2012, In : Journal of Organic Chemistry. 77, 2, p. 1202-1207 6 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2013

An integrated approach to the discovery of potent agelastatin A analogues for brain tumors: Chemical synthesis and biological, physicochemical and CNS pharmacokinetic analyses

Li, Z., Shigeoka, D., Caulfield, T. R., Kawachi, T., Qiu, Y., Kamon, T., Arai, M., Tun, H. W. & Yoshimitsu, T., Jul 1 2013, In : MedChemComm. 4, 7, p. 1093-1098 6 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Dichlorination of olefins with NCS/Ph3P

Kamada, Y., Kitamura, Y., Tanaka, T. & Yoshimitsu, T., Mar 14 2013, In : Organic and Biomolecular Chemistry. 11, 10, p. 1598-1601 4 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Formal synthesis of (-)-agelastatin A: An iron(II)-mediated cyclization strategy

Shigeoka, D., Kamon, T. & Yoshimitsu, T., May 3 2013, In : Beilstein Journal of Organic Chemistry. 9, p. 860-865 6 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Potent growth inhibitory activity of (±)-platencin towards multi-drug-resistant and extensively drug-resistant Mycobacterium tuberculosis

Moustafa, G. A. I., Nojima, S., Yamano, Y., Aono, A., Arai, M., Mitarai, S., Tanaka, T. & Yoshimitsu, T., Apr 2013, In : MedChemComm. 4, 4, p. 720-723 4 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Structure-activity relationships of hybrid annonaceous acetogenins: Powerful growth inhibitory effects of their connecting groups between heterocycle and hydrophobic carbon chain bearing THF ring on human cancer cell lines

Kojima, N., Fushimi, T., Tatsukawa, T., Yoshimitsu, T., Tanaka, T., Yamori, T., Dan, S., Iwasaki, H. & Yamashita, M., Apr 16 2013, In : European Journal of Medicinal Chemistry. 63, p. 833-839 7 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2014

A new route to platencin via decarboxylative radical cyclization

Moustafa, G. A. I., Saku, Y., Aoyama, H. & Yoshimitsu, T., Nov 18 2014, In : Chemical Communications. 50, 99, p. 15706-15709 4 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
1 Citation (Scopus)

Endeavors to access molecular complexity: Strategic use of free radicals in natural product synthesis

Yoshimitsu, T., Apr 2014, In : Chemical Record. 14, 2, p. 268-279 12 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2015

Total Synthesis of Clavilactone B: A Radical Cyclization-Fragmentation Strategy

Suizu, H., Shigeoka, D., Aoyama, H. & Yoshimitsu, T., Jan 2 2015, In : Organic Letters. 17, 1, p. 126-129 4 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2016

Diversity Oriented Synthesis of Allocolchicinoids with Fluoro and/or Oxygen Substituent(s) on the C-Ring from a Single Common Intermediate

Takubo, K., Furutsu, K., Ide, T., Nemoto, H., Ueda, Y., Tsujikawa, K., Ikawa, T., Yoshimitsu, T. & Akai, S., Mar 1 2016, In : European Journal of Organic Chemistry. 2016, 8, p. 1562-1576 15 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2017

2-aminoethoxydiphenyl borate provides an anti-oxidative effect and mediates cardioprotection during ischemia reperfusion in mice

Morihara, H., Obana, M., Tanaka, S., Kawakatsu, I., Tsuchiyama, D., Mori, S., Suizu, H., Ishida, A., Kimura, R., Tsuchimochi, I., Maeda, M., Yoshimitsu, T., Fujio, Y. & Nakayama, H., Dec 1 2017, In : PLoS One. 12, 12, e0189948.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Compounds, compositions, and methods of agelastatin alkaloids: patent evaluation of WO2015042239 (A1)

Yoshimitsu, T. & Tun, H. W., Feb 1 2017, In : Expert Opinion on Therapeutic Patents. 27, 2, p. 113-119 7 p.

Research output: Contribution to journalArticle