• 1480 Citations
  • 21 h-Index
1978 …2020

Research output per year

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Research Output

  • 1480 Citations
  • 21 h-Index
  • 107 Article
  • 6 Review article
  • 1 Chapter
  • 1 Comment/debate
2004

Induction and prevention of virus-associated malignant lymphoma by serial transmission of EBV-related virus from cynomolgus by blood transfusion in rabbits

Koirala, T. R., Hayashi, K., Jin, Z., Onoda, S., Tanaka, T., Oda, W., Ichimura, K., Ohara, N., Oka, T., Yamada, M. & Yoshino, T., Apr 1 2004, In : Acta medica Okayama. 58, 2, p. 67-74 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Thymic myoid cells as a myasthenogenic antigen and antigen-presenting cells

Matsumoto, M. Y., Matsuo, H., Oka, T., Fukudome, T., Hayashi, K., Shiraishi, H., Motomura, M., Shibuya, N. & Ayabe, H., May 1 2004, In : Journal of Neuroimmunology. 150, 1-2, p. 80-87 8 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2003

Activated Proliferation of B-Cell Lymphomas/Leukemias with the SHP1 Gene Silencing by Aberrant CpG Methylation

Koyama, M., Oka, T., Ouchida, M., Nakatani, Y., Nishiuchi, R., Yoshino, T., Hayashi, K., Akagi, T. & Seino, Y., Dec 1 2003, In : Laboratory Investigation. 83, 12, p. 1849-1858 10 p.

Research output: Contribution to journalArticle

58 Citations (Scopus)

Rabbit model for human EBV-associated hemophagocytic syndrome (HPS): Sequential autopsy analysis and characterization of IL-2-dependent cell lines established from Herpesvirus papio-induced fatal rabbit lymphoproliferative diseases with HPS

Hayashi, K., Jin, Z., Onoda, S., Joko, H., Teramoto, N., Ohara, N., Oda, W., Tanaka, T., Liu, Y. X., Koirala, T. R., Oka, T., Kondo, E., Yoshino, T., Takahashi, K. & Akagi, T., May 1 2003, In : American Journal of Pathology. 162, 5, p. 1721-1736 16 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Therapeutic trials for a rabbit model of EBV-associated Hemophagocytic Syndrome (HPS): Effects of vidarabine or CHOP, and development of Herpesvirus papio (HVP)-negative lymphomas surrounded by HVP-infected lymphoproliferative disease

Hayashi, K., Joko, H., Koirala, T. R., Onoda, S., Jin, Z. S., Munemasa, M., Ohara, N., Oda, W., Tanaka, T., Oka, T., Kondo, E., Yoshino, T., Takahashi, K., Yamada, M. & Akagi, T., Oct 1 2003, In : Histology and Histopathology. 18, 4, p. 1155-1168 14 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2002

Expression of heat shock protein 60 in normal and neoplastic human lymphoid tissues.

Oka, T., 2002, In : J Clin Exp Hematopathol. 42, 1, p. 25-32 8 p.

Research output: Contribution to journalArticle

Gene silencing of the tyrosine phosphatase SHP1 gene by aberrant methylation in leukemias/lymphomas

Oka, T., Ouchida, M., Koyama, M., Ogama, Y., Takada, S., Nakatani, Y., Tanaka, T., Yoshino, T., Hayashi, K., Ohara, N., Kondo, E., Takahashi, K., Tsuchiyama, J., Tanimoto, M., Shimizu, K. & Akagi, T., Nov 15 2002, In : Cancer Research. 62, 22, p. 6390-6394 5 p.

Research output: Contribution to journalArticle

170 Citations (Scopus)
2001

An animal model for human EBV-associated hemophagocytic syndrome: Herpesvirus papio frequently induces fatal lymphoproliferative disorders with hemophagocytic syndrome in rabbits

Hayashi, K., Ohara, N., Teramoto, N., Onoda, S., Chen, H. L., Oka, T., Kondo, E., Yoshino, T., Takahashi, K., Yates, J. & Akagi, T., Jan 1 2001, In : American Journal of Pathology. 158, 4, p. 1533-1542 10 p., 64104.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Loss of expression of α4β7 integrin and L-selectin is associated with high-grade progression of low-grade MALT lymphoma

Liu, Y. X., Yoshino, T., Ohara, N., Oka, T., Jin, Z. S., Hayashi, K. & Akagi, T., Nov 28 2001, In : Modern Pathology. 14, 8, p. 798-805 8 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Morphological interactions of interdigitating dendritic cells with B and T cells in human mesenteric lymph nodes

Takahashi, K., Kenji, A., Norihiro, T., Eisaku, K., Takashi, O., Kazuhiko, H., Tadashi, Y. & Tadaatsu, A., Jul 2001, In : American Journal of Pathology. 159, 1, p. 131-138 8 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Myasthenogenisity of thymic myoid cell.

Oka, T., 2001, In : J. Neuroimmunol. 118, p. 163-163 1 p.

Research output: Contribution to journalArticle

Recent advances in DNA microarrays.

Nakanishi, T., Oka, T. & Akagi, T., Dec 2001, In : Acta medica Okayama. 55, 6, p. 319-328 10 p.

Research output: Contribution to journalReview article

15 Citations (Scopus)

Reduction of hematopoietic cell-specific tyrosine phosphatase SHP-1 gene expression in natural killer cell lymphoma and various types of lymphomas/leukemias: Combination Analysis with cDNA expression array and tissue microarray

Oka, T., Yoshino, T., Hayashi, K., Ohara, N., Nakanishi, T., Yamaai, Y., Hiraki, A., Aoki Sogawa, C. A., Kondo, E., Teramoto, N., Takahashi, K., Tsuchiyama, J. & Akagi, T., Oct 2001, In : American Journal of Pathology. 159, 4, p. 1495-1505 11 p.

Research output: Contribution to journalArticle

101 Citations (Scopus)
2000

Characterization of Epstein-Barr virus-infected mantle cell lymphoma lines

Jin, Z., Teramoto, N., Yoshino, T., Takada, K., Oka, T., Hayashi, K. & Akagi, T., Dec 1 2000, In : Acta medica Okayama. 54, 5, p. 193-200 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Differentiation of rat thymic myoid progenitor cell line established by coculture with human T-lymphotropic virus type-I-producing human T cells

Oka, T., Hayashi, K., Nakaoka, Y., Ohtsuki, Y. & Akagi, T., Apr 28 2000, In : Cell and Tissue Research. 300, 1, p. 119-127 9 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Epstein-Barr virus infection to Epstein-Barr virus-negative nasopharyngeal carcinoma cell line TW03 enhances its tumorigenicity

Teramoto, N., Maeda, A., Kobayashi, K., Hayashi, K., Oka, T., Takahashi, K., Takada, K., Klein, G. & Akagi, T., Mar 2000, In : Laboratory Investigation. 80, 3, p. 303-312 10 p.

Research output: Contribution to journalArticle

Open Access
22 Citations (Scopus)

Sequence analysis and variation of EBNA-1 in Epstein-Barr virus-related herpesvirus of cynomolgus monkey

Ohara, N., Hayashi, K., Teramoto, N., Oka, T., Fujimoto, K., Yoshikawa, Y., Castanos-Velez, E., Biberfeld, P. & Akagi, T., Aug 2000, In : Intervirology. 43, 2, p. 102-106 5 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
1999

Cyno-EBV (EBV-related herpesvirus from cynomolgus macaques) induces rabbit malignant lymphomas and their tumor cell lines frequently show specific chromosomal abnormalities

Hayashi, K., Chen, H. L., Yanai, H., Koirala, T. R., Ohara, N., Teramoto, N., Oka, T., Yoshino, T., Takahashi, K., Miyamoto, K., Fujimoto, K., Yoshikawa, Y. & Akagi, T., Jul 1 1999, In : Laboratory Investigation. 79, 7, p. 823-835 13 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
1998

Characterization of a novel human natural killer-cell line (NK-YS) established from natural killer cell lymphoma/leukemia associated with Epstein-Barr virus infection

Tsuchiyama, J., Yoshino, T., Mori, M., Kondoh, E., Oka, T., Akagi, T., Hiraki, A., Nakayama, H., Shibuya, A., Ma, Y., Kawabata, T., Okada, S. & Harada, M., Aug 15 1998, In : Blood. 92, 4, p. 1374-1383 10 p.

Research output: Contribution to journalArticle

71 Citations (Scopus)

Evidence for specific immune response against P210 BCR-ABL in long-term remission CML patients treated with interferon

Oka, T., Sastry, K. J., Nehete, P., Schapiro, S. J., Guo, J. Q., Talpaz, M. & Arlinghaus, R. B., Jan 1 1998, In : Leukemia. 12, 2, p. 155-163 9 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

P53 protein expression in Non-HodgKins lymphomas is infrequently related to p53 gene mutation

Oka, T., 1998, In : Pathol. Int.. 48, p. 15-21 7 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
1997

Analysis of the Genome of an Epstein-Barr-Virus (EBV)-Related Herpesvirus in a Cynomolgus Monkey Cell Line (Si-IIA)

Ino, H., Hayashi, K., Yanai, H., Teramoto, N., Koirala, T. R., Chen, H. L., Oka, T., Yoshino, T., Takahashi, K. & Akagi, T., Aug 1 1997, In : Acta medica Okayama. 51, 4, p. 207-212 6 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
1996

Metastatic potential of lymphoma/leukemia cell lines in SCID mice is closely related to expression of CD44

Kawasaki, N., Matsuo, Y., Yoshino, T., Yanai, H., Oka, T., Teramoto, N., Liu, C., Kondo, E., Minowada, J. & Akagi, T., Oct 1996, In : Japanese Journal of Cancer Research. 87, 10, p. 1070-1077 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
1995

A case of adult human herpesvirus-6 associated hemophagocytic syndrome recovered from acute liver failure

Oka, T., Shinzaki, H., Torimoto, Y., Hasebe, C., Fujimoto, Y., Mizuno, M., Kohda, H., Hirai, K., Takemori, N., Sekiya, C. & Kohgo, Y., Jan 1 1995, In : Japanese Journal of Gastroenterology. 92, 8, p. 1194-1199 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
1993

Aberrant Expression of the p53 Tumor Suppressor Gene in Adult T‐Cell Leukemia and HTLV‐I‐infected Cells

Yamato, K., Oka, T., Hiroi, M., Iwahara, Y., Sugito, S., Tsuchida, N. & Miyoshi, I., Jan 1993, In : Japanese Journal of Cancer Research. 84, 1, p. 4-8 5 p.

Research output: Contribution to journalArticle

54 Citations (Scopus)

Morphological characterization of a new human epithelioid sarcoma cell line, ES020488, in vitro and in vivo

Sonobe, H., Furihata, M., Iwata, J., Oka, T., Ohtsuki, Y., Hamasato, S. & Fujimoto, S., Dec 1 1993, In : Virchows Archiv B Cell Pathology Including Molecular Pathology. 63, 1, p. 219-225 7 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
1992

Establishment and characterization of a new human synovial sarcoma cell line, HS-SY-II

Sonobe, H., Manabe, Y., Furihata, M., Iwata, J., Oka, T., Ohtsuki, Y., Mizobuchi, H., Yamamoto, H., Kumano, O. & Abe, S., Jan 1 1992, In : Laboratory Investigation. 67, 4, p. 498-505 8 p.

Research output: Contribution to journalArticle

71 Citations (Scopus)

Inhibitory effects of human interferons on the immortalization of HUMAN, but not rabbit, T lymphocytes by human T‐lymphotropic virus type‐I (HTLV‐I)

Oka, T., Iwata, J., Furihata, M., Sonobe, H., Miyoshi, I. & Ohtsuki, Y., Jul 30 1992, In : International Journal of Cancer. 51, 6, p. 915-920 6 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Phenotypic progression of a rat lymphoid cell line immortalized by human T-lymphotropic virus type I to induce lymphoma/leukemia-like disease in rats

Oka, T., Sonobe, H., Iwata, J., Kubonishi, I., Satoh, H., Takata, M., Tanaka, Y., Tateno, M., Tozawa, H., Mori, S., Yoshiki, T. & Ohtsuki, Y., Jan 1 1992, In : Journal of Virology. 66, 11, p. 6686-6694 9 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Plant defence and molecular evolution.

Oka, T., 1992, In : The Heredity,. 46, p. 51-57 7 p.

Research output: Contribution to journalArticle

Similarity, in molecular structure and function, between the plant toxin purothionin and the mammalian pore-forming proteins

Oka, T., Murata, Y., Nakanishi, T., Yoshizumi, H., Hayashida, H., Ohtsuki, Y., Toyoshima, K. & Hakura, A., Jan 1 1992, In : Molecular Biology and Evolution. 9, 4, p. 707-715 9 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)
1991

Adult T-cell leukemia/lymphoma with skin lesions similar to mycosis fungoides.(共著)

Oka, T., 1991, In : Rinshou Hifu. 45, p. 17-21 5 p.

Research output: Contribution to journalArticle

Characterization of two human lymphoid cell lines producing human T-lymphotropic virus type I (HTLV-I) isolated from patients with HTLV-I-associated myelopathy or encephalopathy

Iwata, J., Oka, T., Furihata, M., Sonobe, H., Matsubayashi, K., Uemura, Y., Miyoshi, I. & Ohtsuki, Y., Mar 1 1991, In : Archives of Virology. 118, 1-2, p. 101-112 12 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Morphological characterization of a newly established human osteosarcoma cell line, HS-Os-1, revealing its distinct osteoblastic nature

Sonobe, H., Mizobuchi, H., Manabe, Y., Furihata, M., Iwata, J., Hikita, T., Oka, T., Ohtsuki, Y. & Goto, T., Dec 1 1991, In : Virchows Archiv B Cell Pathology Including Molecular Pathology. 60, 1, p. 181-187 7 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Single cilium in human leukemic cells heterotransplanted into hamsters

Ohtsuki, Y., Kubonishi, I., Sonobe, H., Iwata, J., Oka, T. & Miyoshi, I., Jan 1 1991, In : Acta Anatomica. 141, 1, p. 42-45 4 p.

Research output: Contribution to journalArticle

1990

Characterization of flat revertants isolated from cells transformed by Abelson murine leukemia virus (Ab‐MuLV)

Oka, T., Yutsudo, M., Inoue, H., Higuchi, F. & Hakura, A., Dec 1990, In : Journal of cellular physiology. 145, 3, p. 428-433 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Establishment and characterization of a cell line, HS-Os-1 derived from an osteoblastic type of human osteosarcoma

Sonobe, H., Mizobuchi, H., Manabe, Y., Furihata, M., Iwata, J., Hikita, T., Kiuna, O., Tanimoto, T., Oka, T. & Ohtsuki, Y., Jun 1990, In : Human cell : official journal of Human Cell Research Society. 3, 2, p. 148-151 4 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Establishment and characterization of a human cell line, HS-MM, derived from a case of clear cell sarcoma

Sonobe, H., Manabe, Y., Furihata, M., Iwata, J., Hikita, T., Tanimoto, T., Kiuna, O., Oka, T., Ohtsuki, Y. & Mizobuchi, H., Dec 1990, In : Human cell : official journal of Human Cell Research Society. 3, 4, p. 352-356 5 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Suppressive effects of interferons on the production and release of human T-lymphotropic virus type-I (HTLV-I)

Oka, T., Ohtsuki, Y., Sonobe, H., Furihata, M. & Miyoshi, I., Mar 1 1990, In : Archives of Virology. 115, 1-2, p. 63-73 11 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Ultrastructural and immunoelectron microscopic observation of human T-lymphotropic virus type I (HTLV-I) with high voltage electron microscope

Ohtsuki, Y., Iwata, J., Furihata, M., Hikita, T., Mizobuchi, H., Manabe, Y., Oka, T., Ido, E., Sonobe, H. & Miyoshi, I., Dec 1 1990, In : Journal of Clinical Electron Microscopy. 23, 4, p. 373-381 9 p.

Research output: Contribution to journalArticle

1989

Electron microscopic study of suppressive effects on the production of human T-lymphotropic virus type I (HTLV-I)1 with human interferons

Ohtsuki, Y., Oka, T., Furihata, M., Takahashi, K., Hayashi, K., Iwata, J., Hikita, T., Sonobe, H. & Miyoshi, I., Jan 1 1989, In : Journal of Clinical Electron Microscopy. 22, 2, p. 205-213 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Immortalization of rat spleen and thymus T cells by human T-cell leukemia virus type I

Akagi, T., Takata, H., Yoshino, T., Teramoto, N., Yano, S. & Oka, T., Jan 1 1989, In : Acta medica Okayama. 43, 3, p. 143-150 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Inactivation and Activation of Inward Current During Adaptation to Potassium Ions in Paramecium Caudatum

Oka, T. & Nakaoka, Y., 1989, In : Cell Structure and Function. 14, 2, p. 209-216 8 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
1988

Immunocytochemical and ultrastructural characterization of human T-lymphotropic virus type I (HTLV-I)-producing rabbit lymphoid cell lines

Ohtsuki, Y., Miyoshi, I., Oka, T., Hayashi, K., Takahashi, K., Furihata, M., Iwata, J., Takeuchi, T. & Sonobe, H., Sep 1 1988, In : Archives of Virology. 100, 3-4, p. 245-254 10 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)