• 16119 Citations
  • 58 h-Index
19972019
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Fingerprint Dive into the research topics where Shinichi Toyooka is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 60 Similar Profiles
Non-Small Cell Lung Carcinoma Medicine & Life Sciences
Lung Neoplasms Medicine & Life Sciences
Epidermal Growth Factor Receptor Medicine & Life Sciences
Lung Medicine & Life Sciences
Methylation Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Lung Transplantation Medicine & Life Sciences
Mutation Medicine & Life Sciences

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Research Output 1997 2019

  • 16119 Citations
  • 58 h-Index
  • 347 Article
  • 3 Review article
  • 1 Editorial

Acquired resistance mechanisms to afatinib in HER2-amplified gastric cancer cells

Yoshioka, T., Shien, K., Takeda, T., Takahashi, Y., Kurihara, E., Ogoshi, Y., Namba, K., Torigoe, H., Sato, H., Tomida, S., Yamamoto, H., Sou, J., Fujiwara, T. & Toyooka, S., Jan 1 2019, In : Cancer Science.

Research output: Contribution to journalArticle

Open Access
Stomach Neoplasms
Cell Line
BIBW 2992
human ERBB2 protein
Drug Resistance
4 Citations (Scopus)

Activation of AXL as a preclinical acquired resistance mechanism against osimertinib treatment in EGFR-mutant non-small cell lung cancer cells

Namba, K., Shien, K., Takahashi, Y., Torigoe, H., Sato, H., Yoshioka, T., Takeda, T., Kurihara, E., Ogoshi, Y., Yamamoto, H., Sou, J., Tomida, S. & Toyooka, S., Feb 1 2019, In : Molecular Cancer Research. 17, 2, p. 499-507 9 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Cell Line
Therapeutics
Up-Regulation
Protein-Tyrosine Kinases

Anti-tumor effect of neratinib against lung cancer cells harboring HER2 oncogene alterations

Ogoshi, Y., Shien, K., Yoshioka, T., Torigoe, H., Sato, H., Sakaguchi, M., Tomida, S., Namba, K., Kurihara, E., Takahashi, Y., Suzawa, K., Yamamoto, H., Sou, J. & Toyooka, S., Mar 1 2019, In : Oncology Letters. 17, 3, p. 2729-2736 8 p.

Research output: Contribution to journalArticle

Open Access
Oncogenes
Lung Neoplasms
Non-Small Cell Lung Carcinoma
Neoplasms
Protein-Tyrosine Kinases

Application of amplicon-based targeted sequencing with the molecular barcoding system to detect uncommon minor EGFR mutations in patients with treatment-naïve lung adenocarcinoma

Namba, K., Tomida, S., Matsubara, T., Takahashi, Y., Kurihara, E., Ogoshi, Y., Yoshioka, T., Takeda, T., Torigoe, H., Sato, H., Shien, K., Yamamoto, H., Sou, J., Tsukuda, K. & Toyooka, S., Feb 26 2019, In : BMC Cancer. 19, 1, 175.

Research output: Contribution to journalArticle

Open Access
Epidermal Growth Factor Receptor
Mutation
Therapeutics
Non-Small Cell Lung Carcinoma
Adenocarcinoma of lung

A Prospective Cohort Study to Define the Clinical Features and Outcome of Lung Cacers Harboring HER2 Aberration in Japan (HER2-CS STUDY)

Ninomiya, K., Hata, T., Yoshioka, H., Oohashi, K., Bessho, A., Hosokawa, S., Ishikawa, N., Yamasaki, M., Shibayama, T., Aoe, K., Kozuki, T., Harita, S., Ueda, Y., Murakami, T., Fujimoto, N., Yanai, H., Toyooka, S., Takata, M., Hotta, K., Kiura, K. & 108 others, Gemba, K., Ikeda, G., Yasugi, M., Kurimoto, E., Nakano, K., Moritaka, T., Inoue, K., Miyoshi, S., Hamaguchi, N., Ito, R., Sano, Y., Takata, I., Mitani, A., Nishisaka, T., Shoda, H., Nishida, A., Tamamoto, S., Fujitaka, K., Masuda, T., Miyamoto, S., Hattori, N., Sugimoto, K., Fujii, S., Ueda, Y., Sakugawa, Y., Fukamatsu, N., Ogata, K., Bandoh, S., Kanaji, N., Takigawa, N., Yamane, H., Ochi, N., Honda, Y., Oka, M., Kittaka, M., Kubota, T., Yokoyama, A., Yokoyama, T., Sato, E., Shiota, Y., Horita, N., Kanematsu, T., Awaya, Y., Nakamasu, A., Murakami, I., Kuyama, S., Kudo, K., Tamura, T., Umeno, T., Morichika, D., Fujiwara, K., Sato, K., Harada, D., Nogami, N., Nishii, K., Fuchimoto, Y., Kishimoto, T., Kawai, H., Watanabe, K., Tokumo, K., Isobe, T., Tsubata, Y., Inoue, M., Ichikawa, H., Nishioka, Y., Hanibuchi, M., Goto, H., Sumikawa, T., Kodani, M., Suyama, H., Makino, H., Kinosita, N., Shimizu, E., Obata, H., Ikegami, H., Chikamori, K., Maeda, T., Kishino, T., Kamei, H., Ueoka, H., Kunihiro, Y., Kobayashi, T., Ueda, K., Hayashi, M., Kamiya, M., Murakami, J., Sato, A., Ichihara, E., Kubo, T., Ninomiya, T., Hirata, T., Minami, D., Kato, Y., Higo, H., Makimoto, G., Toyota, Y., Oda, N., Nakanishi, M., Kayatani, H., Senoo, S., Kano, H., Watanabe, H., Ando, T., Nakasuka, T., Hara, N., Itano, J., Nakashima, H. & Tabata, M., Jan 1 2019, In : Chest.

Research output: Contribution to journalArticle

Epidermal Growth Factor
Japan
Cohort Studies
Prospective Studies
Lung