If you made any changes in Pure these will be visible here soon.

Research Output 1980 2019

  • 2379 Citations
  • 24 h-Index
  • 140 Article
  • 3 Chapter
2019

Chloroethylating anticancer drug-induced mutagenesis and its repair in Escherichia coli

Yamada, Y., Watanabe, S., Okamoto, K., Arimoto, S., Takahashi, E., Negishi, K. & Negishi, T., Apr 5 2019, In : Genes and Environment. 41, 1, 11.

Research output: Contribution to journalArticle

Open Access
Nimustine
Mutagenesis
DNA Repair
Carmustine
repair

Isolation and identification of photoproducts from UVA-irradiated mixture of N-nitrosoproline with 2'-deoxyadenosine

Aoyama, S., Asahi, C., Sano, K., Kimura, S., Suzuki, T., Hatano, T. & Arimoto, S., May 15 2019, In : Journal of Photochemistry and Photobiology A: Chemistry. 377, p. 159-166 8 p.

Research output: Contribution to journalArticle

isolation
Irradiation
saturation
irradiation
Saturation (materials composition)
2018
1 Citation (Scopus)

2,6-Dimethoxy-1,4-benzoquinone, isolation and identification of anti-carcinogenic, anti-mutagenic and anti-inflammatory component from the juice of Vitis coignetiae

Kamiya, T., Tanimoto, Y., Fujii, N., Negishi, T., Suzuki, T., Hatano, T. & Arimoto, S., Dec 1 2018, In : Food and Chemical Toxicology. 122, p. 172-180 9 p.

Research output: Contribution to journalArticle

benzoquinones
Vitis
juices
Anti-Inflammatory Agents
caftaric acid
1 Citation (Scopus)

Increase of somatic cell mutations in oxidative damage-sensitive drosophila

Koike, R., Uchiyama, T., Arimoto, S., Okamoto, K. & Negishi, T., Jan 1 2018, In : Genes and Environment. 40, 1, 3.

Research output: Contribution to journalArticle

Drosophila
mutation
Uric Acid
Mutation
damage
1 Citation (Scopus)
Frameshift Mutation
mutagenicity
ketone
Ketones
mutation
2017
2 Citations (Scopus)

E. coli mismatch repair enhances AT-to-GC mutagenesis caused by alkylating agents

Nakano, K., Yamada, Y., Takahashi, E., Arimoto, S., Okamoto, K., Negishi, K. & Negishi, T., Mar 1 2017, In : Mutation Research - Genetic Toxicology and Environmental Mutagenesis. 815, p. 22-27 6 p.

Research output: Contribution to journalArticle

DNA Mismatch Repair
Alkylating Agents
Mutagenesis
Escherichia coli
Mutation
2 Citations (Scopus)

Mutation spectrum resulting in M13mp2 phage DNA exposed to N-nitrosoproline with UVA irradiation

Horai, Y., Ando, Y., Kimura, S. & Arimoto, S., Sep 1 2017, In : Mutation Research - Genetic Toxicology and Environmental Mutagenesis. 821, p. 1-4 4 p.

Research output: Contribution to journalArticle

Bacteriophages
Mutation
DNA
Guanine
DNA Adducts
2016
3 Citations (Scopus)
Aeromonas
Hemolysin Proteins
Staphylococcus aureus
Hemolysis
Bacteria
6 Citations (Scopus)

Inhibitory effect of Actinidia arguta on mutagenesis, inflammation and two-stage mouse skin tumorigenesis

Nishimura, M., Okimasu, Y., Miyake, N., Tada, M., Hida, R., Negishi, T. & Arimoto, S., 2016, In : Genes and Environment. 38, 1, 25.

Research output: Contribution to journalArticle

Actinidia
Mutagenesis
skin
Carcinogenesis
2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline
1 Citation (Scopus)

Somatic-cell mutation induced by short exposures to cigarette smoke in urate-null, oxidative stress-sensitive Drosophila

Uchiyama, T., Koike, R., Yuma, Y., Okamoto, K., Arimoto, S., Suzuki, T. & Negishi, T., Jan 1 2016, In : Mutagenesis. 31, 1, p. 9-15 7 p.

Research output: Contribution to journalArticle

Oxidative stress
Uric Acid
Smoke
Tobacco Products
Drosophila
2015
1 Citation (Scopus)

Mutagenicity and clastogenicity of extracts of Helicobacter pylori detected by the Ames test and in the micronucleus test using human lymphoblastoid cells

Arimoto, S., Ohta, K., Yuhara, Y., Ayabe, Y., Negishi, T., Okamoto, K., Nakajima, Y., Ishikawa, T., Oguma, K. & Otsuka, T., Jul 1 2015, In : Mutagenesis. 30, 4, p. 537-544 8 p.

Research output: Contribution to journalArticle

Micronucleus Tests
Helicobacter pylori
Alkylating Agents
Methylnitrosourea
Molecules
20 Citations (Scopus)

RXR partial agonist produced by side chain repositioning of alkoxy RXR full agonist retains antitype 2 diabetes activity without the adverse effects

Kawata, K., Morishita, K. I., Nakayama, M., Yamada, S., Kobayashi, T., Furusawa, Y., Arimoto, S., Oohashi, T., Makishima, M., Naitou, H., Ishitsubo, E., Tokiwa, H., Tai, A. & Kakuta, H., Jan 22 2015, In : Journal of Medicinal Chemistry. 58, 2, p. 912-926 15 p.

Research output: Contribution to journalArticle

Carboxylic Acids
Glucose
Peroxisome Proliferator-Activated Receptors
Oral Administration
pyridine
2014

Effects of oral administration of non-genotoxic hepato-hypertrophic compounds on metabolic potency of rat liver

Fang, X., Nunoshiba, T., Yoshida, M., Nishikawa, A., Nemoto, K., Degawa, M., Arimoto, S., Okamoto, K., Takahashi, E. & Negishi, T., 2014, In : Genes and Environment. 36, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

Oral Administration
decabromobiphenyl ether
enzyme
mutagenicity
Dimethylnitrosamine
2 Citations (Scopus)

Mutagenicity and NO formation from UVA irradiated N-nitrosoproline, and characterization of photoproduct formed in UVA-irradiated mixture of N-nitrosoproline with 2-′deoxyguanosine in neutral solution

Arimoto, S., Machida, M., Sano, K., Aoyama, S., Asahi, C., Tanaka, N., Okamoto, K., Negishi, T., Kimura, S. & Suzuki, T., 2014, In : Genes and Environment. 36, 2, p. 47-53 7 p.

Research output: Contribution to journalArticle

Deoxyguanosine
mutagenicity
nitric oxide
oxygen
Reactive Oxygen Species
3 Citations (Scopus)

Photogenotoxicity and photomutagenicity of medicines, carcinogens and endogenous compounds

Arimoto, S., 2014, In : Genes and Environment. 36, 3, p. 103-110 8 p.

Research output: Contribution to journalArticle

carcinogen
Carcinogens
medicine
drug
Anti-Bacterial Agents
12 Citations (Scopus)

Properties of hemolysin and protease produced by Aeromonas trota

Takahashi, E., Ozaki, H., Fujii, Y., Kobayashi, H., Yamanaka, H., Arimoto, S., Negishi, T. & Okamoto, K., Mar 14 2014, In : PLoS One. 9, 3, e91149.

Research output: Contribution to journalArticle

Aeromonas trota
Aeromonas
Hemolysin Proteins
hemolysins
Peptide Hydrolases
4 Citations (Scopus)

Somatic cell mutations caused by 365 nm LED-UVA due to DNA double-strand breaks through oxidative damage

Fang, X., Ide, N., Higashi, S. I., Kamei, Y., Toyooka, T., Ibuki, Y., Kawai, K., Kasai, H., Okamoto, K., Arimoto, S. & Negishi, T., 2014, In : Photochemical and Photobiological Sciences. 13, 9, p. 1338-1346 9 p.

Research output: Contribution to journalArticle

Double-Stranded DNA Breaks
mutations
Drosophila melanogaster
strands
Light emitting diodes
2013
4 Citations (Scopus)

Analysis of carboxy terminal domain of metalloprotease of elastolytic Aeromonas hydrophila

Takahashi, E., Kobayashi, H., Yamanaka, H., Nakanishi, M., Tateishi, A., Abe, T., Arimoto, S., Negishi, T. & Okamoto, K., Jul 2013, In : Biological and Pharmaceutical Bulletin. 36, 7, p. 1174-1182 9 p.

Research output: Contribution to journalArticle

Aeromonas hydrophila
Metalloproteases
Adenosine Monophosphate
Elastin
Amino Acids
9 Citations (Scopus)

Chemopreventive effects of the juice of vitis coignetiae pulliat on two-stage mouse skin carcinogenesis

Arimoto, S., Zhang, X., Yuhara, Y., Kamiya, T., Negishi, T. & Okamoto, G., Apr 1 2013, In : Nutrition and Cancer. 65, 3, p. 440-450 11 p.

Research output: Contribution to journalArticle

Vitis
Carcinogenesis
Skin
Tetradecanoylphorbol Acetate
9,10-Dimethyl-1,2-benzanthracene
6 Citations (Scopus)

Distinct pathways for repairing mutagenic lesions induced by methylating and ethylating agents

Taira, K., Kaneto, S., Nakano, K., Watanabe, S., Takahashi, E., Arimoto, S., Okamoto, K., Schaaper, R. M., Negishi, K. & Negishi, T., May 2013, In : Mutagenesis. 28, 3, p. 341-350 10 p.

Research output: Contribution to journalArticle

DNA Mismatch Repair
Repair
DNA Repair
Alkylation
Mutagenesis
3 Citations (Scopus)

Near ultraviolet radiation-mediated reaction between N-nitrosoproline and DNA: Isolation and identification of two new adducts, (R)- and (S)-8-(2-pyrrolidyl)-2′-deoxyguanosine

Aoyama, S., Sano, K., Asahi, C., Machida, M., Okamoto, K., Negishi, T., Kimura, S., Suzuki, T., Hatano, T. & Arimoto, S., Feb 15 2013, In : Journal of Photochemistry and Photobiology A: Chemistry. 276, p. 1-7 7 p.

Research output: Contribution to journalArticle

near ultraviolet radiation
Deoxyguanosine
Ultraviolet radiation
adducts
isolation

Spermidine-analogous triamines suppressed the growth of candida albicans

Takahashi, E., Oono, S., Yamamoto, S., Arimoto, S., Negishi, T. & Okamoto, K., Sep 2013, In : Biological and Pharmaceutical Bulletin. 36, 9, p. 1440-1447 8 p.

Research output: Contribution to journalArticle

Spermidine
Candida albicans
Polyamines
Enzyme Inhibitors
Growth
2012
1 Citation (Scopus)

Novel antimutagenic proteins in the edible mushroom Agrocybe cylindracea

Yoneda, K., Shiozawa, A., Kitahara, A., Takahashi, E., Arimoto, S., Okamoto, K. & Negishi, T., 2012, In : Genes and Environment. 34, 1, p. 9-17 9 p.

Research output: Contribution to journalArticle

Agrocybe
Agaricales
mushroom
Ammonium Sulfate
ammonium sulfate

Production and properties of lipase of Aeromonas sobria

Takahashi, E., Ito, H., Kobayashi, H., Yamanaka, H., Takeda, Y., Balakrish Nair, G., Arimoto, S., Negishi, T. & Okamoto, K., May 2012, In : Microbiology and Immunology. 56, 5, p. 295-307 13 p.

Research output: Contribution to journalArticle

Aeromonas
Lipase
Seawater
Genes
Proteins

サルナシの抗発癌・抗炎症機能性

Arimoto, S., 2012, In : ニューフードインダストリー.

Research output: Contribution to journalArticle

2011
13 Citations (Scopus)
Vitis
Amines
2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline
Carbolines
Cytochrome P-450 CYP1A2
4 Citations (Scopus)

Exposure to cigarette smoke increases urate level and decreases glutathione level in larval Drosophila melanogaster

Fujiwara, M., Hamatake, Y., Arimoto, S., Okamoto, K., Suzuki, T. & Negishi, T., 2011, In : Genes and Environment. 33, 3, p. 89-95 7 p.

Research output: Contribution to journalArticle

Uric Acid
Drosophila melanogaster
Smoke
Tobacco Products
smoke
5 Citations (Scopus)

Inhibition of biosynthesis of metalloprotease of Aeromonas sobria by sodium chloride in the medium

Takahashi, E., Kobayashi, H., Yamanaka, H., Nair, G. B., Takeda, Y., Arimoto, S., Negishi, T. & Okamoto, K., Jan 2011, In : Microbiology and Immunology. 55, 1, p. 60-65 6 p.

Research output: Contribution to journalArticle

Aeromonas
Metalloproteases
Adenosine Monophosphate
Sodium Chloride
Serine Proteases
16 Citations (Scopus)
Keratinocytes
Disulfoton
Phototoxic Dermatitis
Zinc Oxide
Methoxsalen
2010
8 Citations (Scopus)

Maturation pathway of metalloprotease produced by Aeromonas sobria

Takahashi, E., Fujii, Y., Kobayashi, H., Yamanaka, H., Nair, G. B., Takeda, Y., Arimoto, S., Negishi, T. & Okamoto, K., Oct 2010, In : Microbiology and Immunology. 54, 10, p. 596-605 10 p.

Research output: Contribution to journalArticle

Aeromonas
Metalloproteases
Serine Proteases
Adenosine Monophosphate
Nucleic Acid Databases

Nitrosation of Glutathione and Nitration of Tyrosine by N-Nitrosoproline with Ultraviolet Light

Arimoto, S., 2010, In : Genes and Environment. 32, 4, p. 75-84 10 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
Dimethylnitrosamine
N-Nitrosopyrrolidine
DNA Damage
Diethylnitrosamine
Nitrosamines
2009
4 Citations (Scopus)

Chlorophyll

Hayatsu, H., Negishi, T. & Arimoto, S., Jul 16 2009, Chemoprevention of Cancer and DNA Damage by Dietary Factors. Wiley-VCH Verlag GmbH & Co. KGaA, p. 699-708 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Aflatoxins
Chemoprevention
Chlorophyll
Carcinogens
chlorin e4
6 Citations (Scopus)

Hypersensitivity of a Urate-null Strain of Drosophila melanogaster to the Toxic Effects of Environmental Cigarette Smoke

Hamatake, Y., Morita, A., Yuma, Y., Okamoto, K., Arimoto, S., Suzuki, T., Kasai, H., Kawai, K. & Negishi, T., 2009, In : Genes and Environment. 31, 2, p. 43-46 4 p.

Research output: Contribution to journalArticle

Poisons
Uric Acid
Drosophila melanogaster
Smoke
Tobacco Products

Protective Effects of Alcoholic Beverages and their Constituent

Saiko, P., Szakmary, A., Szekeres, T., Filipic, M., Plazar, J. & Arimoto, S., Jul 16 2009, Chemoprevention of Cancer and DNA Damage by Dietary Factors. Wiley-VCH Verlag GmbH & Co. KGaA, p. 635-661 27 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Humulus
Stilbenes
Alcoholic Beverages
Polyphenols
Vitamins
2008

Beer and prevention of heterocyclic amine-induced DNA adducts and O6-methylguanine

Arimoto, S., Sep 2008, Beer in Health and Disease Prevention. Elsevier, p. 889-899 11 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

heterocyclic amines
DNA adducts
Beer
DNA Adducts
beers
7 Citations (Scopus)

Binding of MutS protein to oligonucleotides containing a methylated or an ethylated guanine residue, and correlation with mutation frequency

Taira, K., Nakamura, S., Nakano, K., Maehara, D., Okamoto, K., Arimoto, S., Loakes, D., Worth, L., Schaaper, R. M., Seio, K., Sekine, M., Negishi, K. & Negishi, T., Apr 2 2008, In : Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 640, 1-2, p. 107-112 6 p.

Research output: Contribution to journalArticle

Guanine
Mutation Rate
Oligonucleotides
DNA Mismatch Repair
Thymine
5 Citations (Scopus)

Influence of neighbouring base sequences on the mutagenesis induced by 7,8-dihydro-8-oxoguanine in yeast

Yung, C. W., Okugawa, Y., Otsuka, C., Okamoto, K., Arimoto, S., Loakes, D., Negishi, K. & Negishi, T., Nov 2008, In : Mutagenesis. 23, 6, p. 509-513 5 p.

Research output: Contribution to journalArticle

Mutagenesis
Yeast
Yeasts
DNA-Directed DNA Polymerase
Oligonucleotides
1 Citation (Scopus)

Kinetics of dCTP incorporation opposite to 7,8-dihydro-8-oxoguanine with different 5' nearest neighbors by yeast polymerase eta.

Yung, C. W., Loakes, D., Arimoto, S., Negishi, K. & Negishi, T., 2008, In : Nucleic acids symposium series (2004). 52, p. 531-532 2 p.

Research output: Contribution to journalArticle

Yeasts
Cytosine
Mutation
DNA Damage
Nucleotides
2007
7 Citations (Scopus)
Nitrosamines
DNA Breaks
Photosensitizing Agents
Tobacco
Mutation
8 Citations (Scopus)
DNA Adducts
Enzymes
Glucuronosyltransferase
Uridine Diphosphate
Cytochrome P-450 CYP1A1
4 Citations (Scopus)

Mutagenicity in the Surface Waters from Rivers in the UK and Japan from 1997 to 2005

Arimoto-Kobayashi, S., Lord, G. A. & Hayatsu, H., 2007, In : Genes and Environment. 29, 2, p. 67-73 7 p.

Research output: Contribution to journalArticle

mutagenicity
Rivers
Japan
surface water
Water
2006
12 Citations (Scopus)

Cleavage specificity of the serine protease of Aeromonas sobria, a member of the kexin family of subtilases

Kobayashi, H., Takahashi, E., Oguma, K., Fujii, Y., Yamanaka, H., Negishi, T., Arimoto, S., Tsuji, T. & Okamoto, K., Mar 2006, In : FEMS Microbiology Letters. 256, 1, p. 165-170 6 p.

Research output: Contribution to journalArticle

Aeromonas
Serine Proteases
Furin
Peptide Hydrolases
Catalytic Domain
17 Citations (Scopus)

Inhibition of PhIP-induced mammary carcinogenesis in female rats by ingestion of freeze-dried beer

Nozawa, H., Nakao, W., Takata, J., Arimoto, S. & Kondo, K., Apr 8 2006, In : Cancer Letters. 235, 1, p. 121-129 9 p.

Research output: Contribution to journalArticle

Carcinogenesis
Breast
Eating
Neoplasms
High Fat Diet

Inhibitory effect of beer on the clastgenicity of N-nitroso compounds

Arimoto, S., 2006, In : Trace Nutrients Research. 23, p. 109-114 6 p.

Research output: Contribution to journalArticle