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Research Output 2005 2019

  • 4374 Citations
  • 33 h-Index
  • 62 Article
  • 1 Review article
2019
1 Citation (Scopus)

Association between rapid antigen detection tests and antibiotics for acute pharyngitis in Japan: A retrospective observational study

Teratani, Y., Hagiya, H., Koyama, T., Ohshima, A., Zamami, Y., Tatebe, Y., Tasaka, K., Shinomiya, K., Kitamura, Y., Sendo, T., Hinotsu, S. & Kano, M. R., Jan 1 2019, (Accepted/In press) In : Journal of Infection and Chemotherapy.

Research output: Contribution to journalArticle

Pharyngitis
Observational Studies
Japan
Retrospective Studies
Anti-Bacterial Agents

Fall-related mortality trends in older Japanese adults aged ≥65 years: A nationwide observational study

Hagiya, H., Koyama, T., Zamami, Y., Tatebe, Y., Funahashi, T., Shinomiya, K., Kitamura, Y., Hinotsu, S., Sendo, T., Rakugi, H. & Kano, M. R., Dec 11 2019, In : BMJ Open. 9, 12, e033462.

Research output: Contribution to journalArticle

Open Access
Observational Studies
Mortality
Population
Japan
Public Health
4 Citations (Scopus)

In vivo rendezvous of small nucleic acid drugs with charge-matched block catiomers to target cancers

Watanabe, S., Hayashi, K., Toh, K., Kim, H. J., Liu, X., Chaya, H., Fukushima, S., Katsushima, K., Kondo, Y., Uchida, S., Ogura, S., Nomoto, T., Takemoto, H., Cabral, H., Kinoh, H., Tanaka, H., Kano, M., Matsumoto, Y., Fukuhara, H., Uchida, S. & 5 others, Nangaku, M., Osada, K., Nishiyama, N., Miyata, K. & Kataoka, K., Apr 24 2019, In : Nature communications. 10, 1, p. 1894 1894.

Research output: Contribution to journalArticle

Open Access
rendezvous
oligonucleotides
nucleic acids
Oligonucleotides
Nucleic Acids

Oral anticoagulants usage in Japanese patients aged 18-74 years with non-valvular atrial fibrillation: a retrospective analysis based on insurance claims data

Ohshima, A., Koyama, T., Ogawa, A., Zamami, Y., Tanaka, H. Y., Kitamura, Y., Sendo, T., Hinotsu, S., Miller, M. W. & Kano, M. R., Nov 18 2019, In : Family practice. 36, 6, p. 685-692 8 p.

Research output: Contribution to journalArticle

Insurance
Anticoagulants
Atrial Fibrillation
Warfarin
Embolism
3 Citations (Scopus)

Pancreatic stellate cells derived from human pancreatic cancer demonstrate aberrant SPARC-dependent ECM remodeling in 3D engineered fibrotic tissue of clinically relevant thickness

Tanaka, H., Kitahara, K., Sasaki, N., Nakao, N., Sato, K., Narita, H., Shimoda, H., Matsusaki, M., Nishihara, H., Masamune, A. & Kano, M., Feb 1 2019, In : Biomaterials. 192, p. 355-367 13 p.

Research output: Contribution to journalArticle

Pancreatic Stellate Cells
Pancreatic Neoplasms
Extracellular Matrix
Cysteine
Tissue
2 Citations (Scopus)

Pattern of antibiotic prescriptions for outpatients with acute respiratory tract infections in Japan, 2013-15: a retrospective observational study

Teratani, Y., Hagiya, H., Koyama, T., Adachi, M., Ohshima, A., Zamami, Y., Tanaka, H. Y., Tatebe, Y., Tasaka, K., Mikami, N., Shinomiya, K., Kitamura, Y., Kano, M. R., Hinotsu, S. & Sendo, T., Jul 31 2019, In : Family practice. 36, 4, p. 402-409 8 p.

Research output: Contribution to journalArticle

Respiratory Tract Infections
Observational Studies
Prescriptions
Japan
Outpatients

Search for therapeutic agents for cardiac arrest using a drug discovery tool and large-scale medical information database

Zamami, Y., Niimura, T., Koyama, T., Shigemi, Y., Izawa-Ishizawa, Y., Morita, M., Ohshima, A., Harada, K., Imai, T., Hagiwara, H., Okada, N., Goda, M., Takechi, K., Chuma, M., Kondo, Y., Tsuchiya, K., Hinotsu, S., Kano, M. R. & Ishizawa, K., Jan 1 2019, In : Frontiers in Pharmacology. 10, 1257.

Research output: Contribution to journalArticle

Open Access
Drug Discovery
Heart Arrest
Databases
Pharmaceutical Preparations
Isosorbide Dinitrate
2018
5 Citations (Scopus)

In vitro 3D blood/lymph-vascularized human stromal tissues for preclinical assays of cancer metastasis

Nishiguchi, A., Matsusaki, M., Kano, M., Nishihara, H., Okano, D., Asano, Y., Shimoda, H., Kishimoto, S., Iwai, S. & Akashi, M., Oct 1 2018, In : Biomaterials. 179, p. 144-155 12 p.

Research output: Contribution to journalArticle

Lymph
Assays
Blood
Cells
Tissue
7 Citations (Scopus)

Stromal barriers to nanomedicine penetration in the pancreatic tumor microenvironment

Tanaka, H. & Kano, M., Jul 1 2018, In : Cancer Science. 109, 7, p. 2085-2092 8 p.

Research output: Contribution to journalReview article

Nanomedicine
Tumor Microenvironment
Pancreatic Neoplasms
Stromal Cells
Permeability

Trends in incidence and mortality of tuberculosis in Japan: A population-based study, 1997-2016

Hagiya, H., Koyama, T., Zamami, Y., Minato, Y., Tatebe, Y., Mikami, N., Teratani, Y., Ohshima, A., Shinomiya, K., Kitamura, Y., Sendo, T., Hinotsu, S., Tomono, K. & Kano, M. R., Jan 1 2018, (Accepted/In press) In : Epidemiology and Infection.

Research output: Contribution to journalArticle

Japan
Tuberculosis
Mortality
Incidence
Population
3 Citations (Scopus)

Trends in Polypharmacy in Japan: A Nationwide Retrospective Study

Onoue, H., Koyama, T., Zamami, Y., Hagiya, H., Tatebe, Y., Mikami, N., Shinomiya, K., Kitamura, Y., Hinotsu, S., Sendo, T., Ouchi, Y. & Kano, M. R., Jan 1 2018, (Accepted/In press) In : Journal of the American Geriatrics Society.

Research output: Contribution to journalArticle

Polypharmacy
Japan
Retrospective Studies
Confidence Intervals
Health Insurance
2017
8 Citations (Scopus)

Desmoplastic Reaction in 3D-Pancreatic Cancer Tissues Suppresses Molecular Permeability

Matsusaki, M., Komeda, M., Mura, S., Tanaka, H., Kano, M., Couvreur, P. & Akashi, M., 2017, (Accepted/In press) In : Advanced healthcare materials.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Permeability
Cells
Tissue
Fibroblasts

Hydrocortisone administration was associated with improved survival in Japanese patients with cardiac arrest

Niimura, T., Zamami, Y., Koyama, T., Izawa-Ishizawa, Y., Miyake, M., Koga, T., Harada, K., Ohshima, A., Imai, T., Kondo, Y., Imanishi, M., Takechi, K., Fukushima, K., Horinouchi, Y., Ikeda, Y., Fujino, H., Tsuchiya, K., Tamaki, T., Hinotsu, S., Kano, M. & 1 others, Ishizawa, K., Dec 1 2017, In : Scientific Reports. 7, 1, 17919.

Research output: Contribution to journalArticle

Heart Arrest
Hydrocortisone
Survival
Survival Rate
Length of Stay
3 Citations (Scopus)

Regulation of endothelial Fas expression as a mechanism of promotion of vascular integrity by mural cells in tumors

Kamei, R., Tanaka, H., Kawano, T., Morii, C., Tanaka, S., Nishihara, H., Iwata, C. & Kano, M., May 1 2017, In : Cancer Science. 108, 5, p. 1080-1088 9 p.

Research output: Contribution to journalArticle

Blood Vessels
Neoplasms
Colon
Endothelial Cells
Hemorrhage
2016
10 Citations (Scopus)

Increased fibrosis and impaired intratumoral accumulation of macromolecules in a murine model of pancreatic cancer co-administered with FGF-2

Sakai, S., Iwata, C., Tanaka, H., Cabral, H., Morishita, Y., Miyazono, K. & Kano, M., May 28 2016, In : Journal of Controlled Release. 230, p. 109-115 7 p.

Research output: Contribution to journalArticle

Fibroblast Growth Factor 2
Pancreatic Neoplasms
Fibrosis
Neoplasms
Adenocarcinoma
52 Citations (Scopus)

Systemically Injectable Enzyme-Loaded Polyion Complex Vesicles as in Vivo Nanoreactors Functioning in Tumors

Anraku, Y., Kishimura, A., Kamiya, M., Tanaka, S., Nomoto, T., Toh, K., Matsumoto, Y., Fukushima, S., Sueyoshi, D., Kano, M., Urano, Y., Nishiyama, N. & Kataoka, K., Jan 11 2016, In : Angewandte Chemie - International Edition. 55, 2, p. 560-565 6 p.

Research output: Contribution to journalArticle

Nanoreactors
Tumors
Enzymes
Prodrugs
Galactosidases
120 Citations (Scopus)

Vascular bursts enhance permeability of tumour blood vessels and improve nanoparticle delivery

Matsumoto, Y., Nichols, J. W., Toh, K., Nomoto, T., Cabral, H., Miura, Y., Christie, R. J., Yamada, N., Ogura, T., Kano, M., Matsumura, Y., Nishiyama, N., Yamasoba, T., Bae, Y. H. & Kataoka, K., Feb 15 2016, (Accepted/In press) In : Nature Nanotechnology.

Research output: Contribution to journalArticle

blood vessels
Blood vessels
Tumors
bursts
delivery
2015
14 Citations (Scopus)

Density-tunable conjugation of cyclic RGD ligands with polyion complex vesicles for the neovascular imaging of orthotopic glioblastomas

Kawamura, W., Miura, Y., Kokuryo, D., Toh, K., Yamada, N., Nomoto, T., Matsumoto, Y., Sueyoshi, D., Liu, X., Aoki, I., Kano, M., Nishiyama, N., Saga, T., Kishimura, A. & Kataoka, K., Jun 1 2015, In : Science and Technology of Advanced Materials. 16, 3, 035004.

Research output: Contribution to journalArticle

Polyethylene glycols
Ligands
Imaging techniques
Magnetic resonance
Iron oxides
61 Citations (Scopus)

Systemic targeting of lymph node metastasis through the blood vascular system by using size-controlled nanocarriers

Cabral, H., Makino, J., Matsumoto, Y., Mi, P., Wu, H., Nomoto, T., Toh, K., Yamada, N., Higuchi, Y., Konishi, S., Kano, M., Nishihara, H., Miura, Y., Nishiyama, N. & Kataoka, K., May 26 2015, In : ACS Nano. 9, 5, p. 4957-4967 11 p.

Research output: Contribution to journalArticle

cardiovascular system
lymphatic system
Micelles
metastasis
blood
2014

Erratum: SPIO-PICsome: Development of a highly sensitive and stealth-capable MRI nano-agent for tumor detection using SPIO-loaded unilamellar polyion complex vesicles (PICsomes) (Journal of Controlled Release (2013) 169 (220-227))

Kokuryo, D., Anraku, Y., Kishimura, A., Tanaka, S., Kano, M., Kershaw, J., Nishiyama, N., Saga, T., Aoki, I. & Kataoka, K., Mar 28 2014, In : Journal of Controlled Release. 178, 1, p. 125 1 p.

Research output: Contribution to journalArticle

Neoplasms
Pharmaceutical Preparations
2 Citations (Scopus)
Nanotechnology
Drug Delivery Systems
Drug Therapy
14 Citations (Scopus)

Nanotechnology and tumor microcirculation

Kano, M., Jul 30 2014, In : Advanced Drug Delivery Reviews. 74, p. 2-11 10 p.

Research output: Contribution to journalArticle

Nanotechnology
Microcirculation
Neoplasms
Nanoparticles
Pharmaceutical Preparations
29 Citations (Scopus)

Polymeric micelles loaded with platinum anticancer drugs target preangiogenic micrometastatic niches associated with inflammation

Wu, H., Cabral, H., Toh, K., Mi, P., Chen, Y. C., Matsumoto, Y., Yamada, N., Liu, X., Kinoh, H., Miura, Y., Kano, M., Nishihara, H., Nishiyama, N. & Kataoka, K., Sep 10 2014, In : Journal of Controlled Release. 189, p. 1-10 10 p.

Research output: Contribution to journalArticle

Micelles
Platinum
Neoplasm Metastasis
Inflammation
Pharmaceutical Preparations
12 Citations (Scopus)

Secretions from placenta, after hypoxia/reoxygenation, can damage developing neurones of brain under experimental conditions

Curtis, D. J., Sood, A., ica, H. L., Phillips, T. J., Nishiguchi, A., Leinster, V. H. L., Coyle, C., Lacharme-Lora, L., Beaumont, O., Kemp, H., Goodall, R., Cornes, L., Giugliano, M., Barone, R. A., Matsusaki, M., Akashi, M., Tanaka, H., Kano, M., McGarvey, J., Halemani, N. D. & 18 others, Simon, K., Keehan, R., Ind, W., Masters, T., Grant, S., Athwal, S., Collett, G., Tannetta, D., Sargent, I. L., Scull-Brown, E., Liu, X., Aquilina, K., Cohen, N., Lane, J. D., Thoresen, M., Hanley, J., Randall, A. & Case, C. P., 2014, In : Experimental Neurology. 261, p. 386-395 10 p.

Research output: Contribution to journalArticle

Placenta
Neurons
Brain
Conditioned Culture Medium
Glutamate Receptors
78 Citations (Scopus)

Targeted gene delivery by polyplex micelles with crowded PEG palisade and cRGD moiety for systemic treatment of pancreatic tumors

Ge, Z., Chen, Q., Osada, K., Liu, X., Tockary, T. A., Uchida, S., Dirisala, A., Ishii, T., Nomoto, T., Toh, K., Matsumoto, Y., Oba, M., Kano, M., Itaka, K. & Kataoka, K., Mar 2014, In : Biomaterials. 35, 10, p. 3416-3426 11 p.

Research output: Contribution to journalArticle

Micelles
Polyethylene glycols
Tumors
Genes
Neoplasms
2013
239 Citations (Scopus)

Cyclic RGD-linked polymeric micelles for targeted delivery of platinum anticancer drugs to glioblastoma through the blood-brain tumor barrier

Miura, Y., Takenaka, T., Toh, K., Wu, S., Nishihara, H., Kano, M., Ino, Y., Nomoto, T., Matsumoto, Y., Koyama, H., Cabral, H., Nishiyama, N. & Kataoka, K., Oct 22 2013, In : ACS Nano. 7, 10, p. 8583-8592 10 p.

Research output: Contribution to journalArticle

Micelles
Platinum
blood
brain
Tumors
41 Citations (Scopus)

SPIO-PICsome: Development of a highly sensitive and stealth-capable MRI nano-agent for tumor detection using SPIO-loaded unilamellar polyion complex vesicles (PICsomes)

Kokuryo, D., Anraku, Y., Kishimura, A., Tanaka, S., Kano, M., Kershaw, J., Nishiyama, N., Saga, T., Aoki, I. & Kataoka, K., 2013, In : Journal of Controlled Release. 169, 3, p. 220-227 8 p.

Research output: Contribution to journalArticle

Neoplasms
Nanoparticles
Contrast Media
Ethylene Glycol
Transmission Electron Microscopy
60 Citations (Scopus)

Targeted therapy of spontaneous murine pancreatic tumors by polymeric micelles prolongs survival and prevents peritoneal metastasis

Cabral, H., Murakami, M., Hojo, H., Terada, Y., Kano, M., Chung, U. I., Nishiyama, N. & Kataoka, K., Jul 9 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 28, p. 11397-11402 6 p.

Research output: Contribution to journalArticle

Micelles
Neoplasm Metastasis
Neoplasms
oxaliplatin
Transgenic Mice
41 Citations (Scopus)

Transcription factor YY1 contributes to tumor growth by stabilizing hypoxia factor hif-1α in a P53-independent manner

Wu, S., Kasim, V., Kano, M., Tanaka, S., Ohba, S., Miura, Y., Miyata, K., Liu, X., Ako Matsuhashi, M., Chung, U. I., Yang, L., Kataoka, K., Nishiyama, N. & Miyagishi, M., Mar 15 2013, In : Cancer Research. 73, 6, p. 1787-1799 13 p.

Research output: Contribution to journalArticle

Yin-Yang
Hypoxia-Inducible Factor 1
Transcription Factors
Growth
Neoplasms
2012
25 Citations (Scopus)

Engineering fibrotic tissue in pancreatic cancer: A novel three-dimensional model to investigate nanoparticle delivery

Hosoya, H., Kadowaki, K., Matsusaki, M., Cabral, H., Nishihara, H., Ijichi, H., Koike, K., Kataoka, K., Miyazono, K., Akashi, M. & Kano, M., Mar 2 2012, In : Biochemical and Biophysical Research Communications. 419, 1, p. 32-37 6 p.

Research output: Contribution to journalArticle

Tissue Engineering
Pancreatic Neoplasms
Tissue engineering
Permeation
Nanoparticles
37 Citations (Scopus)

Homo-catiomer integration into PEGylated polyplex micelle from block-catiomer for systemic anti-angiogenic gene therapy for fibrotic pancreatic tumors

Chen, Q., Osada, K., Ishii, T., Oba, M., Uchida, S., Tockary, T. A., Endo, T., Ge, Z., Kinoh, H., Kano, M., Itaka, K. & Kataoka, K., Jun 2012, In : Biomaterials. 33, 18, p. 4722-4730 9 p.

Research output: Contribution to journalArticle

Gene therapy
Hominidae
Micelles
Genetic Therapy
Transfection
12 Citations (Scopus)

NC-6301, a polymeric micelle rationally optimized for effective release of docetaxel, is potent but is less toxic than native docetaxel in vivo

Harada, M., Iwata, C., Saito, H., Ishii, K., Hayashi, T., Yashiro, M., Hirakawa, K., Miyazono, K., Kato, Y. & Kano, M., 2012, In : International Journal of Nanomedicine. 7, p. 2713-2727 15 p.

Research output: Contribution to journalArticle

docetaxel
Poisons
Micelles
Toxicity
Tumors
40 Citations (Scopus)

PDGFRβ expression in tumor stroma of pancreatic adenocarcinoma as a reliable prognostic marker

Yuzawa, S., Kano, M., Einama, T. & Nishihara, H., Dec 2012, In : Medical Oncology. 29, 4, p. 2824-2830 7 p.

Research output: Contribution to journalArticle

Platelet-Derived Growth Factor Receptors
Adenocarcinoma
Proto-Oncogene Proteins c-sis
Neoplasms
Smooth Muscle
27 Citations (Scopus)

Pericyte-coverage of human tumor vasculature and nanoparticle permeability

Zhang, L., Nishihara, H. & Kano, M., May 2012, In : Biological and Pharmaceutical Bulletin. 35, 5, p. 761-766 6 p.

Research output: Contribution to journalArticle

Pericytes
Nanoparticles
Permeability
Drug Delivery Systems
Neoplasms
53 Citations (Scopus)

Polymeric micelles incorporating (1,2-diaminocyclohexane)platinum (II) suppress the growth of orthotopic scirrhous gastric tumors and their lymph node metastasis

Rafi, M., Cabral, H., Kano, M., Mi, P., Iwata, C., Yashiro, M., Hirakawa, K., Miyazono, K., Nishiyama, N. & Kataoka, K., Apr 30 2012, In : Journal of Controlled Release. 159, 2, p. 189-196 8 p.

Research output: Contribution to journalArticle

Micelles
Stomach Neoplasms
Stomach
Lymph Nodes
Neoplasm Metastasis
2011
1238 Citations (Scopus)

Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size

Cabral, H., Matsumoto, Y., Mizuno, K., Chen, Q., Murakami, M., Kimura, M., Terada, Y., Kano, M., Miyazono, K., Uesaka, M., Nishiyama, N. & Kataoka, K., Dec 2011, In : Nature Nanotechnology. 6, 12, p. 815-823 9 p.

Research output: Contribution to journalArticle

Micelles
Tumors
micelles
tumors
drugs
68 Citations (Scopus)

Antiangiogenic gene therapy of experimental pancreatic tumor by sFlt-1 plasmid DNA carried by RGD-modified crosslinked polyplex micelles

Vachutinsky, Y., Oba, M., Miyata, K., Hiki, S., Kano, M., Nishiyama, N., Koyama, H., Miyazono, K. & Kataoka, K., Jan 5 2011, In : Journal of Controlled Release. 149, 1, p. 51-57 7 p.

Research output: Contribution to journalArticle

Micelles
Genetic Therapy
Plasmids
DNA
Neoplasms
47 Citations (Scopus)

High expression of IL-22 suppresses antigen-induced immune responses and eosinophilic airway inflammation via an IL-10-associated mechanism

Nakagome, K., Imamura, M., Kawahata, K., Harada, H., Okunishi, K., Matsumoto, T., Sasaki, O., Tanaka, R., Kano, M., Chang, H., Hanawa, H., Miyazaki, J. I., Yamamoto, K. & Dohi, M., Nov 15 2011, In : Journal of Immunology. 187, 10, p. 5077-5089 13 p.

Research output: Contribution to journalArticle

Histocompatibility Antigens Class II
Interleukin-10
Inflammation
Genes
interleukin-22
171 Citations (Scopus)

Improving drug potency and efficacy by nanocarrier-mediated subcellular targeting

Murakami, M., Cabral, H., Matsumoto, Y., Wu, S., Kano, M., Yamori, T., Nishiyama, N. & Kataoka, K., Jan 5 2011, In : Science Translational Medicine. 3, 64, 64ra2.

Research output: Contribution to journalArticle

oxaliplatin
Micelles
Platinum
Pharmaceutical Preparations
Neoplasms
80 Citations (Scopus)

Polyplex micelles prepared from ω-cholesteryl PEG-polycation block copolymers for systemic gene delivery

Oba, M., Miyata, K., Osada, K., Christie, R. J., Sanjoh, M., Li, W., Fukushima, S., Ishii, T., Kano, M., Nishiyama, N., Koyama, H. & Kataoka, K., Jan 2011, In : Biomaterials. 32, 2, p. 652-663 12 p.

Research output: Contribution to journalArticle

Ethylene Glycol
Micelles
Polyethylene glycols
Block copolymers
Cholesterol

Theranostic probes

Kano, M., Oct 31 2011, In : Drug Delivery System. 26, 4, p. 386-391 6 p.

Research output: Contribution to journalArticle

Therapeutic Uses
Single-Photon Emission-Computed Tomography
Toxicology
Contrast Media
Pharmacokinetics
51 Citations (Scopus)

Transforming growth factor-Β decreases the cancer-initiating cell population within diffuse-type gastric carcinoma cells

Ehata, S., Johansson, E., Katayama, R., Koike, S., Watanabe, A., Hoshino, Y., Katsuno, Y., Komuro, A., Koinuma, D., Kano, M., Yashiro, M., Hirakawa, K., Aburatani, H., Fujita, N. & Miyazono, K., Apr 7 2011, In : Oncogene. 30, 14, p. 1693-1705 13 p.

Research output: Contribution to journalArticle

Side-Population Cells
Transforming Growth Factors
Stomach
Carcinoma
Population
2010
55 Citations (Scopus)

Antiangiogenic gene therapy of solid tumor by systemic injection of polyplex micelles loading plasmid DNA encoding soluble flt-1

Oba, M., Vachutinsky, Y., Miyata, K., Kano, M., Ikeda, S., Nishiyama, N., Itaka, K., Miyazono, K., Koyama, H. & Kataoka, K., Apr 5 2010, In : Molecular Pharmaceutics. 7, 2, p. 501-509 9 p.

Research output: Contribution to journalArticle

Micelles
Genetic Therapy
Plasmids
Injections
DNA
65 Citations (Scopus)

Enhanced in vivo magnetic resonance imaging of tumors by PEGylated iron-oxide-gold core-shell nanoparticles with prolonged blood circulation properties

Kumagai, M., Sarmat, T. K., Cabral, H., Kaida, S., Sekino, M., Herlambang, N., Osada, K., Kano, M., Nishiyama, N. & Kataoka, K., Sep 1 2010, In : Macromolecular Rapid Communications. 31, 17, p. 1521-1528 8 p.

Research output: Contribution to journalArticle

Hemodynamics
Magnetic resonance
Iron oxides
Gold
Polyethylene glycols
13 Citations (Scopus)

Exogenous introduction of tissue inhibitor of metalloproteinase 2 reduces accelerated growth of TGF-β-disrupted diffuse-type gastric carcinoma

Johansson, E., Komuro, A., Iwata, C., Hagiwara, A., Fuse, Y., Watanabe, A., Morishita, Y., Aburatani, H., Funa, K., Kano, M. & Miyazono, K., Nov 2010, In : Cancer Science. 101, 11, p. 2398-2403 6 p.

Research output: Contribution to journalArticle

Tissue Inhibitor of Metalloproteinase-2
Transforming Growth Factors
Stomach
Carcinoma
Growth
118 Citations (Scopus)

Induction of endothelial nitric oxide synthase, SIRT1, and catalase by statins inhibits endothelial senescence through the Akt pathway

Ota, H., Eto, M., Kano, M., Kahyo, T., Setou, M., Ogawa, S., Iijima, K., Akishita, M. & Ouchi, Y., Nov 2010, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 30, 11, p. 2205-2211 7 p.

Research output: Contribution to journalArticle

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Nitric Oxide Synthase Type III
Catalase
Galactosidases
Pravastatin
79 Citations (Scopus)

LPA4 regulates blood and lymphatic vessel formation during mouse embryogenesis

Sumida, H., Noguchi, K., Kihara, Y., Abe, M., Yanagida, K., Hamano, F., Sato, S., Tamaki, K., Morishita, Y., Kano, M., Iwata, C., Miyazono, K., Sakimura, K., Shimizu, T. & Ishii, S., Dec 2 2010, In : Blood. 116, 23, p. 5060-5070 11 p.

Research output: Contribution to journalArticle

Lymphatic Vessels
Embryonic Development
Blood Vessels
Blood
Embryonic Structures

Treating "intractable" tumours using nanoDDS and TGF-beta inhibitor

Kano, M., Nishihara, H., Kataoka, K. & Miyazono, K., Nov 2010, In : European Cells and Materials. 20, SUPPL.3, p. 134 1 p.

Research output: Contribution to journalArticle

Transforming Growth Factor beta
Tumors
2009
161 Citations (Scopus)

Autophagy is activated by TGF-β and potentiates TGF-β-mediated growth inhibition in human hepatocellular carcinoma cells

Kiyono, K., Suzuki, H. I., Matsuyama, H., Morishita, Y., Komuro, A., Kano, M., Sugimoto, K. & Miyazono, K., Dec 1 2009, In : Cancer Research. 69, 23, p. 8844-8852 9 p.

Research output: Contribution to journalArticle

Autophagy
Transforming Growth Factors
Hepatocellular Carcinoma
Growth
Death-Associated Protein Kinases