• 528 Citations
  • 11 h-Index
1989 …2018
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Research Output 1989 2018

  • 528 Citations
  • 11 h-Index
  • 24 Article
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Article
2018
2 Citations (Scopus)

Conclusive Evidence for OCT4 Transcription in Human Cancer Cell Lines: Possible Role of a Small OCT4-Positive Cancer Cell Population

Miyamoto, T., Mizuno, N., Kosaka, M., Fujitani, Y., Ohno, E. & Ohtsuka, A., Jan 1 2018, (Accepted/In press) In : Stem Cells.

Research output: Contribution to journalArticle

Octamer Transcription Factors
Cell Line
Protein Isoforms
Population
Neoplasms
2014
5 Citations (Scopus)

Immediate differentiation of neuronal cells from stem/progenitor-like cells in the avian iris tissues

Matsushita, T., Fujihara, A., Royall, L., Kagiwada, S., Kosaka, M. & Araki, M., 2014, In : Experimental Eye Research. 123, p. 16-26 11 p.

Research output: Contribution to journalArticle

Iris
Cell Differentiation
Stem Cells
Cell Culture Techniques
Photoreceptor Cells
2013
4 Citations (Scopus)

Architecture of the subendothelial elastic fibers of small blood vessels and variations in vascular type and size

Shinaoka, A., Momota, R., Shiratsuchi, E., Kosaka, M., Kumagishi, K., Nakahara, R., Naito, I. & Ohtsuka, A., Apr 2013, In : Microscopy and Microanalysis. 19, 2, p. 406-414 9 p.

Research output: Contribution to journalArticle

blood vessels
Blood vessels
vessels
fibers
Fibers
2011
24 Citations (Scopus)

Tsukushi functions as a Wnt signaling inhibitor by competing with Wnt2b for binding to transmembrane protein Frizzled4

Ohta, K., Ito, A., Kuriyama, S., Lupo, G., Kosaka, M., Ohnuma, S. I., Nakagawa, S. & Tanaka, H., Sep 6 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 36, p. 14962-14967 6 p.

Research output: Contribution to journalArticle

Low Density Lipoprotein Receptor-Related Protein-6
Low Density Lipoprotein Receptor-Related Protein-5
Ciliary Body
Wnt Signaling Pathway
Iris
2008
28 Citations (Scopus)

Novel variants of Oct-3/4 gene expressed in mouse somatic cells

Mizuno, N. & Kosaka, M., Nov 7 2008, In : Journal of Biological Chemistry. 283, 45, p. 30997-31004 8 p.

Research output: Contribution to journalArticle

Pseudogenes
Genes
Tissue
Stem cells
Polymerase Chain Reaction
2007
45 Citations (Scopus)

Multipotent cells from mammalian iris pigment epithelium

Asami, M., Sun, G., Yamaguchi, M. & Kosaka, M., Apr 1 2007, In : Developmental Biology. 304, 1, p. 433-446 14 p.

Research output: Contribution to journalArticle

Iris
Epithelium
Nestin
Stem Cells
Salamandridae
2006
42 Citations (Scopus)

Developmental ability of cloned embryos from neural stem cells

Mizutani, E., Ohta, H., Kishigami, S., Thuan, N. V., Hikichi, T., Wakayama, S., Kosaka, M., Sato, E. & Wakayama, T., Dec 2006, In : Reproduction. 132, 6, p. 849-857 9 p.

Research output: Contribution to journalArticle

Aptitude
Neural Stem Cells
Cell Nucleus
Embryonic Structures
Cumulus Cells
56 Citations (Scopus)

Retinal stem/progenitor properties of iris pigment epithelial cells

Sun, G., Asami, M., Ohta, H., Kosaka, J. & Kosaka, M., Jan 1 2006, In : Developmental Biology. 289, 1, p. 243-252 10 p.

Research output: Contribution to journalArticle

Iris
Epithelial Cells
Neuroglia
Retina
Retinal Neurons
2004
44 Citations (Scopus)

Adult human retinal pigment epithelial cells capable of differentiating into neurons

Amemiya, K., Haruta, M., Takahashi, M., Kosaka, M. & Eguchi, G., Mar 26 2004, In : Biochemical and Biophysical Research Communications. 316, 1, p. 1-5 5 p.

Research output: Contribution to journalArticle

Retinal Pigments
Neurons
Epithelial Cells
Cells
Tretinoin
2001
143 Citations (Scopus)

Induction of photoreceptor-specific phenotypes in adult mammalian iris tissue

Haruta, M., Kosaka, M., Kanegae, Y., Saito, I., Inoue, T., Kageyama, R., Nishida, A., Honda, Y. & Takahashi, M., 2001, In : Nature Neuroscience. 4, 12, p. 1163-1164 2 p.

Research output: Contribution to journalArticle

Embryonic Induction
Luminescent Proteins
Neurofilament Proteins
Homeodomain Proteins
Genetic Vectors
1999
7 Citations (Scopus)

Localization of FGFR-1 in axotomized and peripheral nerve transplanted ferret retina

Quan, M. Z., Kosaka, M., Watanabe, M. & Fukuda, Y., Dec 16 1999, In : NeuroReport. 10, 18, p. 3903-3907 5 p.

Research output: Contribution to journalArticle

Fibroblast Growth Factor 1
Fibroblast Growth Factor Receptors
Ferrets
Peripheral Nerves
Retina
1998
27 Citations (Scopus)

In vitro culture system for iris-pigmented epithelial cells for molecular analysis of transdifferentiation

Kosaka, M., Kodama, R. & Eguchi, G., Dec 15 1998, In : Experimental Cell Research. 245, 2, p. 245-251 7 p.

Research output: Contribution to journalArticle

Iris
Epithelial Cells
Lenses
Epithelium
Northern Blotting
1995
6 Citations (Scopus)

Induction of teratocarcinoma F9 cell differentiation with cis-diammine dichloroplatinum(II) (CDDP)

Doi, T., Sumi, T., Nishina, Y., Kosaka, M., Iwai, S. A., Sakuda, M. & Nishimune, Y., Jan 6 1995, In : Cancer Letters. 88, 1, p. 81-86 6 p.

Research output: Contribution to journalArticle

Teratocarcinoma
Cell Differentiation
Platinum Compounds
Embryonal Carcinoma
Differentiation Antigens
3 Citations (Scopus)

The kinetics of induction of Hox1.6 and c-jun mRNA during three different ways of inducing differentiation in teratocarcinoma F9 cells

Iwai, S. A., Nishina, Y., Kosaka, M., Sumi, T., Doi, T., Sakuda, M. & Nishimune, Y., 1995, In : In Vitro Cellular and Developmental Biology - Animal. 31, 6, p. 462-466 5 p.

Research output: Contribution to journalArticle

Teratocarcinoma
Messenger RNA
Kinetics
Cell Differentiation
Gene expression
1994
2 Citations (Scopus)

F9 cells can be differentiated toward two distinct, mutually exclusive pathways by retinoic acid and sodium butyrate

Kosaka, M., Takeda, M., Matsumoto, K. & Nishimune, Y., 1994, In : Development Growth and Differentiation. 36, 2, p. 223-230 8 p.

Research output: Contribution to journalArticle

Butyric Acid
Tretinoin
Embryonal Carcinoma Stem Cells
Cell Differentiation
1993
15 Citations (Scopus)

Changes in Hox1.6, c-jun, and Oct-3 gene expressions are associated with teratocarcinoma F9 cell differentiation in three different ways of induction

Iwai, S. A., Kosaka, M., Nishina, Y., Sumi, T., Sakuda, M. & Nishimune, Y., 1993, In : Experimental Cell Research. 205, 1, p. 39-43 5 p.

Research output: Contribution to journalArticle

Teratocarcinoma
Cell Differentiation
Tretinoin
Gene Expression
Genes
2 Citations (Scopus)

Suppression of tumorigenicity in temperature-sensitive mutants of embryonal carcinoma cells by induction of cell differentiation at non-permissive temperature

Sumi, T., Nishina, Y., Kosaka, M., Kosaka, M. & Nishimune, Y., 1993, In : International Journal of Cancer. 54, 2, p. 333-337 5 p.

Research output: Contribution to journalArticle

Embryonal Carcinoma Stem Cells
Cell Differentiation
Temperature
Teratocarcinoma
Cell Cycle
15 Citations (Scopus)

The induction of jun genes during the reversible changes induced with sodium butyrate on the differentiation of F9 cells

Nishina, Y., Sumi, T., Iwai, S. A., Kosaka, M. & Nishimune, Y., 1993, In : Experimental Cell Research. 208, 2, p. 492-497 6 p.

Research output: Contribution to journalArticle

jun Genes
Butyric Acid
Tretinoin
Cell Differentiation
Embryonal Carcinoma Stem Cells
1992
7 Citations (Scopus)

c-myc and p53 gene expression in the differentiation of temperature-sensitive mutants of teratocarcinoma F9 cells

Kosaka, M., Iwai, S. A., Nishina, Y., Sumi, T. & Nishimune, Y., Dec 1992, In : Oncogene. 7, 12, p. 2455-2460 6 p.

Research output: Contribution to journalArticle

Teratocarcinoma
myc Genes
p53 Genes
Gene Expression
Temperature
7 Citations (Scopus)

Expression of c-kit protooncogene is stimulated by cAMP in differentiated F9 mouse teratocarcinoma cells

Nishina, Y., Kobarai, Y., Sumi, T., Kosaka, M., Nishikawa, S. I. & Nishimune, Y., 1992, In : Experimental Cell Research. 198, 2, p. 352-356 5 p.

Research output: Contribution to journalArticle

Teratocarcinoma
Tretinoin
Cell Differentiation
Gametogenesis
Messenger RNA
7 Citations (Scopus)

Teratocarcinoma F9 cells induced to differentiate with sodium butyrate produce both tissue-type and urokinase-type plasminogen activators

Takeda, M., Kosaka, M., Nishina, Y., Sawada, K., Matsumoto, K. & Nishimune, Y., 1992, In : Journal of Cellular Biochemistry. 49, 3, p. 284-289 6 p.

Research output: Contribution to journalArticle

Teratocarcinoma
Butyric Acid
Urokinase-Type Plasminogen Activator
Tissue Plasminogen Activator
Tretinoin
1991
27 Citations (Scopus)

Reversible effects of sodium butyrate on the differentiation of F9 embryonal carcinoma cells

Kosaka, M., Nishina, Y., Takeda, M., Matsumoto, K. & Nishimune, Y., 1991, In : Experimental Cell Research. 192, 1, p. 46-51 6 p.

Research output: Contribution to journalArticle

Embryonal Carcinoma Stem Cells
Butyric Acid
Cell Differentiation
Differentiation Antigens
Messenger RNA
1989
5 Citations (Scopus)
Teratocarcinoma
Nucleic Acid Synthesis Inhibitors
Stem cells
Nucleosides
Cell Differentiation
5 Citations (Scopus)

Isolation of mutants showing temperature-sensitive cell growth from embryonal carcinoma cells: Control of stem cell differentiation by incubation temperatures

Nishimune, Y., Nishina, Y., Sumi, T., Kosaka, M., Takeda, M., Matsumoto, K., Matsushiro, A. & Sakuda, M., Nov 30 1989, In : Biochemical and Biophysical Research Communications. 165, 1, p. 65-72 8 p.

Research output: Contribution to journalArticle

Embryonal Carcinoma Stem Cells
Cell growth
Stem cells
Cell Differentiation
Stem Cells