• 1142 Citations
  • 19 h-Index
20082019

Research output per year

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Research Output

  • 1142 Citations
  • 19 h-Index
  • 31 Article
  • 1 Conference contribution
  • 1 Letter
  • 1 Review article
2019

Export of a Vibrio parahaemolyticus toxin by the Sec and type III secretion machineries in tandem

Matsuda, S., Okada, R., Tandhavanant, S., Hiyoshi, H., Gotoh, K., Iida, T. & Kodama, T., May 1 2019, In : Nature Microbiology. 4, 5, p. 781-788 8 p.

Research output: Contribution to journalLetter

7 Citations (Scopus)
2018

DEC205 mediates local and systemic immune responses to Helicobacter pylori infection in humans

Kita, M., Yokota, K., Kageyama, C., Take, S., Goto, K., Kawahara, Y., Matsushita, O. & Okada, H., Jan 1 2018, In : Oncotarget. 9, 22, p. 15828-15835 8 p.

Research output: Contribution to journalArticle

Vibrio alginolyticus VepA induces lysosomal membrane permeability and cathepsin-independent cell death

Darwinata, A. E., Goto, K., Mima, T., Yamamoto, Y., Yokota, K. & Matsushita, O., Jan 1 2018, In : Acta Medica Okayama. 72, 3, p. 231-239 9 p.

Research output: Contribution to journalArticle

2017

Expression of Collagenase is Regulated by the VarS/VarA Two-Component Regulatory System in Vibrio alginolyticus

Mima, T., Goto, K., Yamamoto, Y., Maeda, K., Shirakawa, T., Matsui, S., Murata, Y., Koide, T., Tokumitsu, H. & Matsushita, O., Oct 9 2017, (Accepted/In press) In : Journal of Membrane Biology. p. 1-13 13 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Fungal ITS1 deep-sequencing strategies to reconstruct the composition of a 26-species community and evaluation of the gut mycobiota of healthy Japanese individuals

Motooka, D., Fujimoto, K., Tanaka, R., Yaguchi, T., Gotoh, K., Maeda, Y., Furuta, Y., Kurakawa, T., Goto, N., Yasunaga, T., Narazaki, M., Kumanogoh, A., Horii, T., Iida, T., Takeda, K. & Nakamura, S., Feb 15 2017, In : Frontiers in Microbiology. 8, FEB, 238.

Research output: Contribution to journalArticle

25 Citations (Scopus)
2016

Dysbiosis Contributes to Arthritis Development via Activation of Autoreactive T Cells in the Intestine

Maeda, Y., Kurakawa, T., Umemoto, E., Motooka, D., Ito, Y., Gotoh, K., Hirota, K., Matsushita, M., Furuta, Y., Narazaki, M., Sakaguchi, N., Kayama, H., Nakamura, S., Iida, T., Saeki, Y., Kumanogoh, A., Sakaguchi, S. & Takeda, K., Nov 1 2016, In : Arthritis and Rheumatology. 68, 11, p. 2646-2661 16 p.

Research output: Contribution to journalArticle

157 Citations (Scopus)

Lypd8 promotes the segregation of flagellated microbiota and colonic epithelia

Okumura, R., Kurakawa, T., Nakano, T., Kayama, H., Kinoshita, M., Motooka, D., Gotoh, K., Kimura, T., Kamiyama, N., Kusu, T., Ueda, Y., Wu, H., Iijima, H., Barman, S., Osawa, H., Matsuno, H., Nishimura, J., Ohba, Y., Nakamura, S., Iida, T. & 4 others, Yamamoto, M., Umemoto, E., Sano, K. & Takeda, K., Apr 7 2016, In : Nature. 532, 7597, p. 117-121 5 p.

Research output: Contribution to journalArticle

64 Citations (Scopus)

Metagenomic Analysis Reveals Dynamic Changes of Whole Gut Microbiota in the Acute Phase of Intensive Care Unit Patients

Ojima, M., Motooka, D., Shimizu, K., Gotoh, K., Shintani, A., Yoshiya, K., Nakamura, S., Ogura, H., Iida, T. & Shimazu, T., Jun 1 2016, In : Digestive Diseases and Sciences. 61, 6, p. 1628-1634 7 p.

Research output: Contribution to journalArticle

49 Citations (Scopus)

Temporal dynamics of bacterial microbiota in the human oral cavity determined using an in situ model of dental biofilms

Wake, N., Asahi, Y., Noiri, Y., Hayashi, M., Motooka, D., Nakamura, S., Gotoh, K., Miura, J., Machi, H., Iida, T. & Ebisu, S., Aug 10 2016, In : npj Biofilms and Microbiomes. 2, 16018.

Research output: Contribution to journalArticle

17 Citations (Scopus)
2015

Baseline assessment of mesophotic reefs of the Vitória-Trindade Seamount Chain based on water quality, microbial diversity, benthic cover and fish biomass data

Meirelles, P. M., Amado-Filho, G. M., Pereira-Filho, G. H., Pinheiro, H. T., De Moura, R. L., Joyeux, J. C., Mazzei, E. F., Bastos, A. C., Edwards, R. A., Dinsdale, E., Paranhos, R., Santos, E. O., Iida, T., Gotoh, K., Nakamura, S., Sawabe, T., Rezende, C. E., Gadelha, L. M. R., Francini-Filho, R. B., Thompson, C. & 1 others, Thompson, F. L., Jun 19 2015, In : PloS one. 10, 6, e0130084.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Functional specialization in regulation and quality control in thermal adaptive evolution

Yama, K., Matsumoto, Y., Murakami, Y., Seno, S., Matsuda, H., Gotoh, K., Motooka, D., Nakamura, S., Ying, B. W. & Yomo, T., Nov 2015, In : Genes to Cells. 20, 11, p. 943-955 13 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Interaction between the Type III Effector VopO and GEF-H1 Activates the RhoA-ROCK Pathway

Hiyoshi, H., Okada, R., Matsuda, S., Gotoh, K., Akeda, Y., Iida, T. & Kodama, T., Mar 1 2015, In : PLoS Pathogens. 11, 3, p. 1-19 19 p., e1004694.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Post-Golgi anterograde transport requires GARP-dependent endosome-to-TGN retrograde transport

Hirata, T., Fujita, M., Nakamura, S., Gotoh, K., Motooka, D., Murakami, Y., Maeda, Y. & Kinoshita, T., Sep 1 2015, In : Molecular Biology of the Cell. 26, 17, p. 3071-3084 14 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Regulation of Vibrio parahaemolyticus T3SS2 gene expression and function of T3SS2 effectors that modulate actin cytoskeleton

Kodama, T., Hiyoshi, H., Okada, R., Matsuda, S., Gotoh, K. & Iida, T., Feb 1 2015, In : Cellular Microbiology. 17, 2, p. 183-190 8 p.

Research output: Contribution to journalReview article

6 Citations (Scopus)
2014

Allergic bronchopulmonary mycosis due to co-infection with Aspergillus fumigatus and Schizophyllum commune

Seki, M., Ohno, H., Gotoh, K., Motooka, D., Nakamura, S., Iida, T., Miyazaki, Y. & Tomono, K., Jan 1 2014, In : IDCases. 1, 1, p. 5-8 4 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

BEC, a novel enterotoxin of clostridium perfringens found in human clinical isolates from acute gastroenteritis outbreaks

Yonogi, S., Matsuda, S., Kawai, T., Yoda, T., Harada, T., Kumeda, Y., Gotoh, K., Hiyoshi, H., Nakamura, S., Kodama, T. & Iida, T., 2014, In : Infection and Immunity. 82, 6, p. 2390-2399 10 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

Complete nucleotide sequence of a plasmid containing the botulinum neurotoxin gene in Clostridium botulinum type B strain 111 isolated from an infant patient in Japan

Hosomi, K., Sakaguchi, Y., Kohda, T., Gotoh, K., Motooka, D., Nakamura, S., Umeda, K., Iida, T., Kozaki, S. & Mukamoto, M., Nov 19 2014, In : Molecular Genetics and Genomics. 289, 6, p. 1267-1274 8 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Comprehensive metagenomic approach for detecting causative microorganisms in culture-negative infective endocarditis

Imai, A., Gotoh, K., Asano, Y., Yamada, N., Motooka, D., Fukushima, M., Kanzaki, M., Ohtani, T., Sakata, Y., Nishi, H., Toda, K., Sawa, Y., Komuro, I., Horii, T., Iida, T., Nakamura, S. & Takashima, S., Mar 15 2014, In : International Journal of Cardiology. 172, 2, p. e288-e289

Research output: Contribution to journalArticle

14 Citations (Scopus)

Generation of colonic IgA-secreting cells in the caecal patch

Masahata, K., Umemoto, E., Kayama, H., Kotani, M., Nakamura, S., Kurakawa, T., Kikuta, J., Gotoh, K., Motooka, D., Sato, S., Higuchi, T., Baba, Y., Kurosaki, T., Kinoshita, M., Shimada, Y., Kimura, T., Okumura, R., Takeda, A., Tajima, M., Yoshie, O. & 6 others, Fukuzawa, M., Kiyono, H., Fagarasan, S., Iida, T., Ishii, M. & Takeda, K., Jan 1 2014, In : Nature communications. 5, 1 p.

Research output: Contribution to journalArticle

56 Citations (Scopus)

Mutation accumulation in bacteria exposed to UV radiation

Shibai, A., Tsuru, S., Ying, B. W., Motooka, D., Gotoh, K., Nakamura, S. & Yomo, T., Jan 1 2014, Artificial Life 14 - Proceedings of the 14th International Conference on the Synthesis and Simulation of Living Systems, ALIFE 2014. Sayama, H., Rieffel, J., Risi, S., Doursat, R. & Lipson, H. (eds.). MIT Press Journals, p. 757-758 2 p. (Artificial Life 14 - Proceedings of the 14th International Conference on the Synthesis and Simulation of Living Systems, ALIFE 2014).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Oral pathobiont induces systemic inflammation and metabolic changes associated with alteration of gut microbiota

Arimatsu, K., Yamada, H., Miyazawa, H., Minagawa, T., Nakajima, M., Ryder, M. I., Gotoh, K., Motooka, D., Nakamura, S., Iida, T. & Yamazaki, K., May 6 2014, In : Scientific reports. 4, 4828.

Research output: Contribution to journalArticle

121 Citations (Scopus)

Performance comparison of second- and third-generation sequencers using a bacterial genome with two chromosomes

Miyamoto, M., Motooka, D., Gotoh, K., Imai, T., Yoshitake, K., Goto, N., Iida, T., Yasunaga, T., Horii, T., Arakawa, K., Kasahara, M. & Nakamura, S., Aug 21 2014, In : BMC Genomics. 15, 1, 699.

Research output: Contribution to journalArticle

50 Citations (Scopus)

Peyer's patches play a protective role in nonsteroidal anti-inflammatory drug-induced enteropathy in mice

Hiyama, S., Iijima, H., Shinzaki, S., Inoue, T., Shiraishi, E., Kawai, S., Araki, M., Kato, M., Hayashi, Y., Nishida, T., Fujii, H., Mukai, A., Shibata, N., Sato, S., Kiyono, H., Gotoh, K., Motooka, D., Nakamura, S., Iida, T., Tsujii, M. & 1 others, Takehara, T., May 2014, In : Inflammatory bowel diseases. 20, 5, p. 790-799 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Physiologic and metagenomic attributes of the rhodoliths forming the largest CaCO3 bed in the South Atlantic Ocean

Cavalcanti, G. S., Gregoracci, G. B., Dos Santos, E. O., Silveira, C. B., Meirelles, P. M., Longo, L., Gotoh, K., Nakamura, S., Iida, T., Sawabe, T., Rezende, C. E., Francini-Filho, R. B., Moura, R. L., Amado-Filho, G. M. & Thompson, F. L., Jan 1 2014, In : ISME Journal. 8, 1, p. 52-62 11 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Severe respiratory failure due to co-infection with human metapneumovirus and Streptococcus pneumoniae

Seki, M., Yoshida, H., Gotoh, K., Hamada, N., Motooka, D., Nakamura, S., Yamamoto, N., Hamaguchi, S., Akeda, Y., Watanabe, H., Iida, T. & Tomono, K., 2014, In : Respiratory Medicine Case Reports. 12, p. 13-15 3 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2013

Fatal sepsis caused by an unusual Klebsiella species that was misidentified by an automated identification system

Seki, M., Gotoh, K., Nakamura, S., Akeda, Y., Yoshii, T., Miyaguchi, S., Inohara, H., Horii, T., Oishi, K., Iida, T. & Tomono, K., May 1 2013, In : Journal of Medical Microbiology. 62, PART5, p. 801-803 3 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Metagenomic Analysis of Healthy and White Plague-Affected Mussismilia braziliensis Corals

Garcia, G. D., Gregoracci, G. B., Santos, E. D. O., Meirelles, P. M., Silva, G. G. Z., Edwards, R., Sawabe, T., Gotoh, K., Nakamura, S., Iida, T., de Moura, R. L. & Thompson, F. L., May 1 2013, In : Microbial Ecology. 65, 4, p. 1076-1086 11 p.

Research output: Contribution to journalArticle

54 Citations (Scopus)

Metagenomic profile of gut microbiota in children during cholera and recovery

Monira, S., Nakamura, S., Gotoh, K., Izutsu, K., Watanabe, H., Alam, N. H., Nakaya, T., Horii, T., Ali, S. I., Iida, T. & Alam, M., Feb 25 2013, In : Gut Pathogens. 5, 1, 1.

Research output: Contribution to journalArticle

39 Citations (Scopus)

Mode of binding of RNA polymerase α subunit to the phased A-tracts upstream of the phospholipase C gene promoter of Clostridium perfringens

Katayama, S., Ishibashi, K., Gotoh, K. & Nakamura, D., Oct 1 2013, In : Anaerobe. 23, p. 62-69 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2011

Gut microbiota of healthy and malnourished children in Bangladesh

Monira, S., Nakamura, S., Gotoh, K., Izutsu, K., Watanabe, H., Alam, N. H., Endtz, H. P., Cravioto, A., Ali, S. I., Nakaya, T., Horii, T., Iida, T. & Alam, M., Jan 1 2011, In : Frontiers in Microbiology. 2, NOV

Research output: Contribution to journalArticle

85 Citations (Scopus)

VopV, an F-actin-binding type III secretion effector, is required for vibrio parahaemolyticus-induced enterotoxicity

Hiyoshi, H., Kodama, T., Saito, K., Gotoh, K., Matsuda, S., Akeda, Y., Honda, T. & Iida, T., Oct 4 2011, In : Cell Host and Microbe. 10, 4, p. 401-409 9 p.

Research output: Contribution to journalArticle

49 Citations (Scopus)
2010

Bile acid-induced virulence gene expression of Vibrio parahaemolyticus reveals a novel therapeutic potential for bile acid sequestrants

Gotoh, K., Kodama, T., Hiyoshi, H., Izutsu, K., Park, K. S., Dryselius, R., Akeda, Y., Honda, T. & Iida, T., Nov 17 2010, In : PloS one. 5, 10, e13365.

Research output: Contribution to journalArticle

74 Citations (Scopus)

Two regulators of Vibrio parahaemolyticus play important roles in enterotoxicity by controlling the expression of genes in the Vp-PAI region

Kodama, T., Gotoh, K., Hiyoshi, H., Morita, M., Izutsu, K., Akeda, Y., Park, K. S., Cantarelli, V. V., Dryselius, R., Iida, T. & Honda, T., Jan 13 2010, In : PloS one. 5, 1, e8678.

Research output: Contribution to journalArticle

39 Citations (Scopus)
2008

Identification of two translocon proteins of Vibrio parahaemolyticus type III secretion system 2

Kodama, T., Hiyoshi, H., Gotoh, K., Akeda, Y., Matsuda, S., Park, K. S., Cantarelli, V. V., Iida, T. & Honda, T., Sep 1 2008, In : Infection and Immunity. 76, 9, p. 4282-4289 8 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)