• 527 Citations
  • 12 h-Index
20012020

Research output per year

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Research Output

  • 527 Citations
  • 12 h-Index
  • 28 Article
  • 3 Review article
2001
1 Citation (Scopus)
2003

Aquifex aeolicus tRNA (Gm18) methyltransferase has unique substrate specificity: tRNA recognition mechanism of the enzyme

Hori, H., Kubota, S., Watanabe, K., Kim, J. M., Ogasawara, T., Sawasaki, T. & Endo, Y., Jul 4 2003, In : Journal of Biological Chemistry. 278, 27, p. 25081-25090 10 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)
2004

Deep knot structure for construction of active site and cofactor binding site of tRNA modification enzyme

Nureki, O., Watanabe, K., Fukai, S., Ishii, R., Endo, Y., Hori, H. & Yokoyama, S., Apr 1 2004, In : Structure. 12, 4, p. 593-602 10 p.

Research output: Contribution to journalArticle

92 Citations (Scopus)

Substrate tRNA recognition mechanism of tRNA (m7G46) methyltransferase from Aquifex aeolicus

Okamoto, H., Watanabe, K., Ikeuchi, Y., Suzuki, T., Endo, Y. & Hori, H., Nov 19 2004, In : Journal of Biological Chemistry. 279, 47, p. 49151-49159 9 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)
2005

Roles of conserved amino acid sequence motifs in the SpoU (TrmH) RNA methyltransferase family

Watanabe, K., Nureki, O., Fukai, S., Ishii, R., Okamoto, H., Yokoyama, S., Endo, Y. & Hori, H., Mar 18 2005, In : Journal of Biological Chemistry. 280, 11, p. 10368-10377 10 p.

Research output: Contribution to journalArticle

54 Citations (Scopus)

Structural change of tRNA (Gm18) methyltransferase by binding of methyl donor analogues.

Watanabe, K., Nureki, O., Fukai, S., Endo, Y. & Hori, H., 2005, In : Nucleic acids symposium series (2004). 49, p. 301-302 2 p.

Research output: Contribution to journalArticle

Open Access
2006

Crystal structures of leucyl/phenylalanyl-tRNA-protein transferase and its complex with an aminoacyl-tRNA analog

Suto, K., Shimizu, Y., Watanabe, K., Ueda, T., Fukai, S., Nureki, O. & Tomita, K., Dec 13 2006, In : EMBO Journal. 25, 24, p. 5942-5950 9 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Functional categorization of the conserved basic amino acid residues in TrmH (tRNA (Gm18) methyltansferase) enzymes

Watanabe, K., Nureki, O., Fukai, S., Endo, Y. & Hori, H., Nov 10 2006, In : Journal of Biological Chemistry. 281, 45, p. 34630-34639 10 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)
2007

Protein-based peptide-bond formation by aminoacyl-tRNA protein transferase

Watanabe, K., Toh, Y., Suto, K., Shimizu, Y., Oka, N., Wada, T. & Tomita, K., Oct 18 2007, In : Nature. 449, 7164, p. 867-871 5 p.

Research output: Contribution to journalArticle

63 Citations (Scopus)
2008

Molecular basis for maintenance of fidelity during the CCA-adding reaction by a CCA-adding enzyme

Toh, Y., Numata, T., Watanabe, K., Takeshita, D., Nureki, O. & Tomita, K., Jul 23 2008, In : EMBO Journal. 27, 14, p. 1944-1952 9 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Molecular basis for peptide-bond formation by aminoacyl-tRNA protein transferase

Watanabe, K. & Tomita, K., Jul 1 2008, In : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 53, 9, p. 1152-1157 6 p.

Research output: Contribution to journalReview article

2009

Molecular basis for peptide-bond formation by an aminoacyl-tRNA protein transferase

Watanabe, K., Toh, Y. & Tomita, K., Sep 9 2009, In : Seikagaku. 81, 4, p. 294-298 5 p.

Research output: Contribution to journalReview article

2012

Formation of tRNA granules in the nucleus of heat-induced human cells

Miyagawa, R., Mizuno, R., Watanabe, K. & Ijiri, K., Feb 3 2012, In : Biochemical and Biophysical Research Communications. 418, 1, p. 149-155 7 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
2013

Degradation of initiator tRNAMet by Xrn1/2 via its accumulation in the nucleus of heat-treated HeLa cells

Watanabe, K., Miyagawa, R., Tomikawa, C., Mizuno, R., Takahashi, A., Hori, H. & Ijiri, K., Apr 2013, In : Nucleic acids research. 41, 8, p. 4671-4685 15 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Near-infrared light-directed RNAi using a photosensitive carrier molecule

Matsushita-Ishiodori, Y., Morinaga, M., Watanabe, K. & Ohtsuki, T., Oct 16 2013, In : Bioconjugate Chemistry. 24, 10, p. 1669-1673 5 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

The catalytic domain of topological knot tRNA methyltransferase (TrmH) discriminates between substrate tRNA and nonsubstrate tRNA via an induced-fit process

Ochi, A., Makabe, K., Yamagami, R., Hirata, A., Sakaguchi, R., Hou, Y. M., Watanabe, K., Nureki, O., Kuwajima, K. & Hori, H., Aug 30 2013, In : Journal of Biological Chemistry. 288, 35, p. 25562-25574 13 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2014

MTOR regulates the nucleoplasmic diffusion of Xrn2 under conditions of heat stress

Watanabe, K., Ijiri, K. & Ohtsuki, T., Sep 17 2014, In : FEBS Letters. 588, 18, p. 3454-3460 7 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Photo-dependent protein biosynthesis using a caged aminoacyl-tRNA

Akahoshi, A., Doi, Y., Sisido, M., Watanabe, K. & Ohtsuki, T., Dec 1 2014, In : Bioorganic and Medicinal Chemistry Letters. 24, 23, p. 5369-5372 4 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2015

The molecular mechanism of photochemical internalization of cell penetrating peptide-cargo-photosensitizer conjugates

Ohtsuki, T., Miki, S., Kobayashi, S., Haraguchi, T., Nakata, E., Hirakawa, K., Sumita, K., Watanabe, K. & Okazaki, S., Dec 21 2015, In : Scientific reports. 5, 18577.

Research output: Contribution to journalArticle

29 Citations (Scopus)
2016

Effects of polyamines from Thermus thermophilus, an extreme-thermophilic eubacterium, on tRNA methylation by tRNA (Gm18) methyltransferase (TrmH)

Hori, H., Terui, Y., Nakamoto, C., Iwashita, C., Ochi, A., Watanabe, K. & Oshima, T., May 1 2016, In : Journal of Biochemistry. 159, 5, p. 509-517 9 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Enhanced cellular uptake of lactosomes using cell-penetrating peptides

Akahoshi, A., Matsuura, E., Ozeki, E., Matsui, H., Watanabe, K. & Ohtsuki, T., Jan 1 2016, In : Science and Technology of Advanced Materials. 17, 1, p. 245-252 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
9 Citations (Scopus)

Photoinduced apoptosis using a peptide carrying a photosensitizer

Watanabe, K., Fujiwara, H., Kitamatsu, M. & Ohtsuki, T., Jul 1 2016, In : Bioorganic and Medicinal Chemistry Letters. 26, 13, p. 3115-3118 4 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Phototriggered protein syntheses by using (7-diethylaminocoumarin-4-yl)methoxycarbonyl-caged aminoacyl tRNAs

Ohtsuki, T., Kanzaki, S., Nishimura, S., Kunihiro, Y., Sisido, M. & Watanabe, K., Aug 17 2016, In : Nature communications. 7, 12501.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2017

Detection of small, highly structured RNAs using molecular beacons

Li, J., Xu, C., Shimada, N., Miyoshi, Y., Watanabe, K., Cong, W. & Ohtsuki, T., May 28 2017, In : Analytical Methods. 9, 20, p. 2971-2976 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Ultrasound-dependent cytoplasmic internalization of a peptide-sonosensitizer conjugate

Inaba, Y., Watanabe, K., Kitamatsu, M., Nakata, E., Harada, A. & Ohtsuki, T., Aug 1 2017, In : Bioorganic and Medicinal Chemistry. 25, 15, p. 4212-4217 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2018

MicroRNA-664a-5p promotes neuronal differentiation of SH-SY5Y cells

Watanabe, K., Yamaji, R. & Ohtsuki, T., Jan 1 2018, (Accepted/In press) In : Genes to Cells.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Red and Near-Infrared Light-Directed Cytosolic Delivery of Two Different RNAs Using Photosensitive RNA Carriers

Shiraga, K., Soe, T. H., Matsumoto, S., Watanabe, K. & Ohtsuki, T., Sep 19 2018, In : Bioconjugate Chemistry. 29, 9, p. 3174-3179 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2019

In-stem molecular beacon targeted to a 5 0 -region of tRNA inclusive of the D arm that detects mature tRNA with high sensitivity

Miyoshi, Y., Ohtsuki, T., Kashida, H., Asanuma, H. & Watanabe, K., Jan 2019, In : PloS one. 14, 1, e0211505.

Research output: Contribution to journalArticle

Relation of Photochemical Internalization to Heat, pH and Ca2+ Ions

Soe, T. H., Nanjo, T., Watanabe, K. & Ohtsuki, T., Jan 1 2019, (Accepted/In press) In : Photochemistry and Photobiology.

Research output: Contribution to journalArticle

2020

Endosomal Escape of Peptide-Photosensitizer Conjugates Is Affected by Amino Acid Sequences near the Photosensitizer

Miyoshi, Y., Kadono, M., Okazaki, S., Nishimura, A., Kitamatsu, M., Watanabe, K. & Ohtsuki, T., Mar 18 2020, In : Bioconjugate Chemistry. 31, 3, p. 916-922 7 p.

Research output: Contribution to journalArticle