Kazuhiko Shien

  • 1119 Citations
  • 16 h-Index
20082019
If you made any changes in Pure these will be visible here soon.

Fingerprint Dive into the research topics where Kazuhiko Shien is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 58 Similar Profiles
Non-Small Cell Lung Carcinoma Medicine & Life Sciences
Lung Neoplasms Medicine & Life Sciences
Chemoradiotherapy Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Epidermal Growth Factor Receptor Medicine & Life Sciences
docetaxel Medicine & Life Sciences
MicroRNAs Medicine & Life Sciences
Cell Line Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2008 2019

  • 1119 Citations
  • 16 h-Index
  • 63 Article
  • 2 Review article
  • 1 Editorial

Acquired resistance mechanisms to afatinib in HER2-amplified gastric cancer cells

Yoshioka, T., Shien, K., Takeda, T., Takahashi, Y., Kurihara, E., Ogoshi, Y., Namba, K., Torigoe, H., Sato, H., Tomida, S., Yamamoto, H., Sou, J., Fujiwara, T. & Toyooka, S., Jan 1 2019, In : Cancer Science.

Research output: Contribution to journalArticle

Open Access
Stomach Neoplasms
Cell Line
BIBW 2992
human ERBB2 protein
Drug Resistance
2 Citations (Scopus)

Activation of AXL as a preclinical acquired resistance mechanism against osimertinib treatment in EGFR-mutant non-small cell lung cancer cells

Namba, K., Shien, K., Takahashi, Y., Torigoe, H., Sato, H., Yoshioka, T., Takeda, T., Kurihara, E., Ogoshi, Y., Yamamoto, H., Sou, J., Tomida, S. & Toyooka, S., Feb 1 2019, In : Molecular Cancer Research. 17, 2, p. 499-507 9 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Cell Line
Therapeutics
Up-Regulation
Protein-Tyrosine Kinases

Application of amplicon-based targeted sequencing with the molecular barcoding system to detect uncommon minor EGFR mutations in patients with treatment-naïve lung adenocarcinoma

Namba, K., Tomida, S., Matsubara, T., Takahashi, Y., Kurihara, E., Ogoshi, Y., Yoshioka, T., Takeda, T., Torigoe, H., Sato, H., Shien, K., Yamamoto, H., Sou, J., Tsukuda, K. & Toyooka, S., Feb 26 2019, In : BMC Cancer. 19, 1, 175.

Research output: Contribution to journalArticle

Open Access
Epidermal Growth Factor Receptor
Mutation
Therapeutics
Non-Small Cell Lung Carcinoma
Adenocarcinoma of lung

Clinical outcome of patients with recurrent non-small cell lung cancer after trimodality therapy

Suzawa, K., Sou, J., Takahashi, Y., Sato, H., Shien, K., Yamamoto, H., Kanazawa, S., Kiura, K., Miyoshi, S. & Toyooka, S., Jan 1 2019, In : Surgery today.

Research output: Contribution to journalReview article

Non-Small Cell Lung Carcinoma
Recurrence
Therapeutics
Survival
Neoplasm Metastasis

Critical role of the MCAM-ETV4 axis triggered by extracellular S100A8/A9 in breast cancer aggressiveness

Chen, Y., Sumardika, I. W., Tomonobu, N., Kinoshita, R., Inoue, Y., Iioka, H., Mitsui, Y., Saito, K., Ruma, I. M. W., Sato, H., Yamauchi, A., Murata, H., Yamamoto, K., Tomida, S., Shien, K., Yamamoto, H., Sou, J., Futami, J., Kubo, M., Putranto, E. W. & 7 others, Murakami, T., Liu, M., Hibino, T., Nishibori, M., Kondo, E., Toyooka, S. & Sakaguchi, M., Jul 1 2019, In : Neoplasia (United States). 21, 7, p. 627-640 14 p.

Research output: Contribution to journalArticle

Open Access
CD146 Antigens
Epithelial-Mesenchymal Transition
Breast Neoplasms
Neoplasm Metastasis
Neoplasms