Kazuhiko Shien

  • 1087 Citations
  • 16 h-Index
20082019
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  • 47 Similar Profiles
Non-Small Cell Lung Carcinoma Medicine & Life Sciences
Lung Neoplasms Medicine & Life Sciences
Chemoradiotherapy Medicine & Life Sciences
Epidermal Growth Factor Receptor Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
docetaxel Medicine & Life Sciences
MicroRNAs Medicine & Life Sciences
Cell Line Medicine & Life Sciences

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Research Output 2008 2019

  • 1087 Citations
  • 16 h-Index
  • 65 Article
  • 2 Review article
  • 1 Editorial
1 Citation (Scopus)

Activation of AXL as a preclinical acquired resistance mechanism against osimertinib treatment in EGFR-mutant non-small cell lung cancer cells

Namba, K., Shien, K., Takahashi, Y., Torigoe, H., Sato, H., Yoshioka, T., Takeda, T., Kurihara, E., Ogoshi, Y., Yamamoto, H., Sou, J., Tomida, S. & Toyooka, S., Feb 1 2019, In : Molecular Cancer Research. 17, 2, p. 499-507 9 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Cell Line
Therapeutics
Up-Regulation
Protein-Tyrosine Kinases

Anti-tumor effect of neratinib against lung cancer cells harboring HER2 oncogene alterations

Ogoshi, Y., Shien, K., Yoshioka, T., Torigoe, H., Sato, H., Sakaguchi, M., Tomida, S., Namba, K., Kurihara, E., Takahashi, Y., Suzawa, K., Yamamoto, H., Sou, J. & Toyooka, S., Mar 1 2019, In : Oncology Letters. 17, 3, p. 2729-2736 8 p.

Research output: Contribution to journalArticle

Open Access
Oncogenes
Lung Neoplasms
Non-Small Cell Lung Carcinoma
Neoplasms
Protein-Tyrosine Kinases

Application of amplicon-based targeted sequencing with the molecular barcoding system to detect uncommon minor EGFR mutations in patients with treatment-naïve lung adenocarcinoma

Namba, K., Tomida, S., Matsubara, T., Takahashi, Y., Kurihara, E., Ogoshi, Y., Yoshioka, T., Takeda, T., Torigoe, H., Sato, H., Shien, K., Yamamoto, H., Sou, J., Tsukuda, K. & Toyooka, S., Feb 26 2019, In : BMC Cancer. 19, 1, 175.

Research output: Contribution to journalArticle

Open Access
Epidermal Growth Factor Receptor
Mutation
Therapeutics
Non-Small Cell Lung Carcinoma
Adenocarcinoma of lung

Clinical outcome of patients with recurrent non-small cell lung cancer after trimodality therapy

Suzawa, K., Sou, J., Takahashi, Y., Sato, H., Shien, K., Yamamoto, H., Kanazawa, S., Kiura, K., Miyoshi, S. & Toyooka, S., Jan 1 2019, In : Surgery today.

Research output: Contribution to journalReview article

Non-Small Cell Lung Carcinoma
Recurrence
Therapeutics
Survival
Neoplasm Metastasis

Droplet digital PCR as a novel system for the detection of microRNA‑34b/c methylation in circulating DNA in malignant pleural mesothelioma

Sato, H., Sou, J., Aoe, K., Fujimoto, N., Tanaka, S., Namba, K., Torigoe, H., Shien, K., Yamamoto, H., Tomida, S., Tao, H., Okabe, K., Kishimoto, T. & Toyooka, S., Jun 1 2019, In : International journal of oncology. 54, 6, p. 2139-2148 10 p.

Research output: Contribution to journalArticle

Methylation
Polymerase Chain Reaction
DNA
MicroRNAs
Disease Progression