• 911 Citations
  • 17 h-Index
20012019
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Research Output 2001 2019

  • 911 Citations
  • 17 h-Index
  • 59 Article
  • 1 Review article
2019

Concise synthesis of anticancer active trans-4-(4-Octylphenyl)prolinol

Ando, J., Tazawa, A., Ishizawa, K., Tanaka, M. & Takamura, H., Jan 1 2019, In : Heterocycles. p. 716-723 8 p.

Research output: Contribution to journalArticle

Aromatic compounds
Halogenation
Acids
prolinol
1 Citation (Scopus)

Stereocontrolled synthesis of the macrolactone core of neopeltolide

Meissner, A., Tanaka, N., Takamura, H. & Kadota, I., Jan 1 2019, (Accepted/In press) In : Tetrahedron Letters.

Research output: Contribution to journalArticle

Allylation
Ether
neopeltolide
1 Citation (Scopus)

Stereodivergent and stereoselective synthesis of cis-and trans-4-substituted prolinols

Ando, J., Tazawa, A., Ishizawa, K., Tanaka, M. & Takamura, H., Jan 1 2019, In : Heterocycles. p. 188-199 12 p.

Research output: Contribution to journalArticle

Derivatives
Hydrogenation
Proline
Oxidation
Catalysts
2018
7 Citations (Scopus)

Convergent total synthesis of (−)-dactylolide

Tanaka, T., Murai, Y., Kishi, T., Takamura, H. & Kadota, I., Feb 21 2018, In : Tetrahedron Letters. 59, 8, p. 763-766 4 p.

Research output: Contribution to journalArticle

Allylation
Acetylation
Esterification
Cyclization
Carboxylic Acids
2 Citations (Scopus)

Formal total synthesis of enigmazole A

Meissner, A., Kishi, T., Fujisawa, Y., Murai, Y., Takamura, H. & Kadota, I., Dec 19 2018, In : Tetrahedron Letters. 59, 51, p. 4492-4495 4 p.

Research output: Contribution to journalArticle

Allylation
Stereoselectivity
Lewis Acids
Macrolides
Carboxylic Acids
1 Citation (Scopus)

Improved synthesis of the AE ring segment of ciguatoxin CTX3C by using intramolecular allylations

Tanaka, T., Asakura, H., Fujiwara, R., Kumamoto, K., Izuka, H., Shiroma, K., Takamura, H. & Kadota, I., Jan 1 2018, In : Bulletin of the Chemical Society of Japan. 91, 4, p. 507-514 8 p.

Research output: Contribution to journalArticle

Allylation
Stereoselectivity
Aldehydes
Ether
ciguatoxin 3C
2 Citations (Scopus)

Recent topics of the stereodivergent synthesis of natural products

Takamura, H., Mar 14 2018, In : Tetrahedron Letters. 59, 11, p. 955-966 12 p.

Research output: Contribution to journalReview article

Biological Products
Stereoisomerism
Lead compounds
Pharmaceutical Preparations
Biological Products
Stereochemistry
Carbon
Nuclear magnetic resonance
symbiodinolide

Total sytnhesis of Rhoiptelol B

Tanaka, N., Takamura, H. & Kadota, I., Jan 1 2018, In : Heterocycles. 97, 2, p. 1157-1164 8 p.

Research output: Contribution to journalArticle

Diarylheptanoids
Allylation
Fruits
Fruit
4 Citations (Scopus)

Unified Total Synthesis, Stereostructural Elucidation, and Biological Evaluation of Sarcophytonolides

Takamura, H., Kikuchi, T., Iwamoto, K., Nakao, E., Harada, N., Otsu, T., Endo, N., Fukuda, Y., Ohno, O., Suenaga, K., Guo, Y. W. & Kadota, I., Sep 21 2018, In : Journal of Organic Chemistry. 83, 18, p. 11028-11056 29 p.

Research output: Contribution to journalArticle

Diterpenes
Cytotoxicity
Toxicity
2017
4 Citations (Scopus)

Late-stage divergent synthesis and antifouling activity of geraniol-butenolide hybrid molecules

Takamura, H., Ohashi, T., Kikuchi, T., Endo, N., Fukuda, Y. & Kadota, I., 2017, In : Organic and Biomolecular Chemistry. 15, 26, p. 5549-5555 7 p.

Research output: Contribution to journalArticle

antifouling
Thoracica
larvae
Molecules
metathesis
2 Citations (Scopus)

Total Synthesis of Two Possible Diastereomers of Natural 6-Chlorotetrahydrofuran Acetogenin and Its Stereostructural Elucidation

Takamura, H., Katsube, T., Okamoto, K. & Kadota, I., Dec 6 2017, In : Chemistry - A European Journal. 23, 68, p. 17191-17194 4 p.

Research output: Contribution to journalArticle

Acetogenins
Chlorination
Cyclization
Nuclear magnetic resonance
Biological Products
2016
16 Citations (Scopus)

Chemical control of xylem differentiation by thermospermine, xylemin, and auxin

Yoshimoto, K., Takamura, H., Kadota, I., Motose, H. & Takahashi, T., Feb 16 2016, In : Scientific Reports. 6, 21487.

Research output: Contribution to journalArticle

Xylem
Indoleacetic Acids
Blood Vessels
Phloem
thermospermine
5 Citations (Scopus)

Stereodivergent Synthesis and Stereochemical Reassignment of the C79-C104 Fragment of Symbiodinolide

Takamura, H., Fujiwara, T., Kawakubo, Y., Kadota, I. & Uemura, D., Feb 5 2016, In : Chemistry - A European Journal. 22, 6, p. 1984-1996 13 p.

Research output: Contribution to journalArticle

Chemical shift
Biological Products
Nuclear magnetic resonance
Stereochemistry
Aldehydes
5 Citations (Scopus)

Stereoselective Synthesis of the Proposed C79-C104 Fragment of Symbiodinolide

Takamura, H., Fujiwara, T., Kawakubo, Y., Kadota, I. & Uemura, D., Feb 5 2016, In : Chemistry - A European Journal. 22, 6, p. 1979-1983 5 p.

Research output: Contribution to journalArticle

Polyols
Chemical shift
Biological Products
Molecular weight
Nuclear magnetic resonance
9 Citations (Scopus)
antifouling
Structure-Activity Relationship
metathesis
closing
synthesis
2015
3 Citations (Scopus)

Convergent synthesis of the EFGH ring system of ciguatoxin CTX3C

Kadota, I., Sato, Y., Fujita, N., Takamura, H. & Yamamoto, Y., Mar 16 2015, In : Tetrahedron. 71, 37, p. 6547-6558 12 p., 26709.

Research output: Contribution to journalArticle

Allylation
Acetals
Ether
ciguatoxin 3C
3 Citations (Scopus)

Stereodivergent synthesis and relative stereostructure of the C1-C13 fragment of symbiodinolide

Takamura, H., Wada, H., Ogino, M., Kikuchi, T., Kadota, I. & Uemura, D., Mar 20 2015, In : Journal of Organic Chemistry. 80, 6, p. 3111-3123 13 p.

Research output: Contribution to journalArticle

Ketones
Aldehydes
Nuclear magnetic resonance
symbiodinolide
methyl acetoacetate
2014
6 Citations (Scopus)

Improvded synthesis of the A-E ring segment of ciguatoxin CTX3C

Shiroma, K., Asakura, H., Tanaka, T., Takamura, H. & Kadota, I., 2014, In : Heterocycles. 88, 2, p. 969-973 5 p.

Research output: Contribution to journalArticle

Allylation
ciguatoxin 3C
4 Citations (Scopus)

Stereocontrolled synthesis of the C1-C7 fragment of enigmazole a

Kishi, T., Fujisawa, Y., Takamura, H. & Kadota, I., 2014, In : Heterocycles. 89, 2, p. 515-522 8 p.

Research output: Contribution to journalArticle

Molecules
enigmazole A
1 Citation (Scopus)
Biological Products
Molecular structure
Molecular weight
Nuclear magnetic resonance
Molecules
2013
3 Citations (Scopus)

Stereoselective synthesis of the C79-C97 fragment of symbiodinolide

Takamura, H., Fujiwara, T., Kadota, I. & Uemura, D., Sep 25 2013, In : Beilstein Journal of Organic Chemistry. 9, p. 1931-1935 5 p.

Research output: Contribution to journalArticle

Biological Products
Molecular weight
symbiodinolide
polyol
13 Citations (Scopus)

Total synthesis, structural elucidation, and structure-cytotoxic activity relationship of (-)-gummiferol

Takamura, H., Wada, H., Lu, N., Ohno, O., Suenaga, K. & Kadota, I., Mar 15 2013, In : Journal of Organic Chemistry. 78, 6, p. 2443-2454 12 p.

Research output: Contribution to journalArticle

Stereoisomerism
Epoxidation
Biological Products
Cells
Nuclear magnetic resonance
13 Citations (Scopus)

Total synthesis of two possible diastereomers of (+)-sarcophytonolide C and its structural elucidation

Takamura, H., Iwamoto, K., Nakao, E. & Kadota, I., 2013, In : Organic Letters. 15, 5, p. 1108-1111 4 p.

Research output: Contribution to journalArticle

metathesis
closing
nuclear magnetic resonance
rings
synthesis
2012
12 Citations (Scopus)

A convergent synthesis of the right-hand fragment of ciguatoxin CTX3C

Takamura, H., Abe, T., Nishiuma, N., Fujiwara, R., Tsukeshiba, T. & Kadota, I., Mar 11 2012, In : Tetrahedron. 68, 10, p. 2245-2260 16 p.

Research output: Contribution to journalArticle

Hydrogenation
Hand
Allylation
Polyethers
ciguatoxin 3C
9 Citations (Scopus)

Stereoselective synthesis of the C94-C104 fragment of symbiodinolide

Takamura, H., Tsuda, K., Kawakubo, Y., Kadota, I. & Uemura, D., Aug 15 2012, In : Tetrahedron Letters. 53, 33, p. 4317-4319 3 p.

Research output: Contribution to journalArticle

Biological Products
Aldehydes
Molecular Weight
Molecular weight
polyol
2 Citations (Scopus)

Synthesis of the E ring segment of ciguatoxin CTX3C via the negishi coupling of cyclic ketene acetal triflates

Shiroma, K., Takamura, H. & Kadota, I., 2012, In : Heterocycles. 86, 2, p. 997-1001 5 p.

Research output: Contribution to journalArticle

Acetals
Lactones
Substrates
ketene
ciguatoxin 3C
2011
9 Citations (Scopus)

Convergent synthesis of the HIJKLM ring system of ciguatoxin CTX3C

Takamura, H., Nishiuma, N., Abe, T. & Kadota, I., Sep 2 2011, In : Organic Letters. 13, 17, p. 4704-4707 4 p.

Research output: Contribution to journalArticle

Allylation
Hydrogenation
Alkylation
metathesis
rings
10 Citations (Scopus)

Total synthesis and absolute configuration of (-)-gummiferol

Takamura, H., Wada, H., Lu, N. & Kadota, I., Jul 15 2011, In : Organic Letters. 13, 14, p. 3644-3647 4 p.

Research output: Contribution to journalArticle

epoxidation
nuclear magnetic resonance
Epoxidation
synthesis
products
2010
4 Citations (Scopus)

A new method for the stereoselective construction of angular methyl group of fuzed cyclic ethers

Kadota, I., Kishi, T., Fujisawa, Y., Yamagami, Y. & Takamura, H., Jul 28 2010, In : Tetrahedron Letters. 51, 30, p. 3960-3961 2 p.

Research output: Contribution to journalArticle

Cyclic Ethers
Ether
Acetals
11 Citations (Scopus)

Stereocontrolled synthesis and structural confirmation of the C14 - C24 degraded fragment of symbiodinolide

Takamura, H., Kadonaga, Y., Kadota, I. & Uemura, D., Sep 18 2010, In : Tetrahedron. 66, 38, p. 7569-7576 8 p.

Research output: Contribution to journalArticle

Stereochemistry
symbiodinolide
penitricin C
9 Citations (Scopus)

Stereoselective synthesis of the C14-C24 degraded fragment of symbiodinolide

Takamura, H., Kadonaga, Y., Kadota, I. & Uemura, D., May 12 2010, In : Tetrahedron Letters. 51, 19, p. 2603-2605 3 p.

Research output: Contribution to journalArticle

Dinoflagellida
Macrolides
symbiodinolide
polyol
penitricin C
17 Citations (Scopus)

Total synthesis of brevenal

Takamura, H., Yamagami, Y., Kishi, T., Kikuchi, S., Nakamura, Y., Kadota, I. & Yamamoto, Y., Jul 17 2010, In : Tetrahedron. 66, 29, p. 5329-5344 16 p.

Research output: Contribution to journalArticle

Ether
Allylation
brevetoxin
2009
9 Citations (Scopus)

A transannular diels-alder strategy to the construction of the CDE ring system of nakiterpiosin

Takamura, H., Yamagami, Y., Ito, T., Ito, M., Arimoto, H., Kadota, I. & Uemurat, D., Jan 1 2009, In : Heterocycles. 77, 1, p. 351-364 14 p.

Research output: Contribution to journalArticle

Alnus
Cycloaddition Reaction
nakiterpiosin
17 Citations (Scopus)

Convergent synthesis of the A-E ring segment of ciguatoxin CTX3C

Kadota, I., Abe, T., Uni, M., Takamura, H. & Yamamoto, Y., Sep 12 2009, In : Tetrahedron. 65, 37, p. 7784-7789 6 p.

Research output: Contribution to journalArticle

Allylation
Ether
ciguatoxin 3C
18 Citations (Scopus)

Determination of absolute configuration of C14-C23 fragment in symbiodinolide

Han, C., Yamano, Y., Kita, M., Takamura, H. & Uemura, D., Sep 16 2009, In : Tetrahedron Letters. 50, 37, p. 5280-5282 3 p.

Research output: Contribution to journalArticle

Lactones
Degradation
Catalysts
symbiodinolide
7 Citations (Scopus)

Selective cleavage of primary MPM ethers with TMSI/Et3N

Kadota, I., Yamagami, Y., Fujita, N. & Takamura, H., Aug 5 2009, In : Tetrahedron Letters. 50, 31, p. 4552-4553 2 p.

Research output: Contribution to journalArticle

Ethers
Acetals
15 Citations (Scopus)

Stereoselective synthesis and absolute configuration of the C1′-C25′ fragment of symbiodinolide

Takamura, H., Murata, T., Asai, T., Kadota, I. & Uemura, D., Sep 4 2009, In : Journal of Organic Chemistry. 74, 17, p. 6658-6666 9 p.

Research output: Contribution to journalArticle

Hydrolysis
symbiodinolide
17 Citations (Scopus)

Stereoselective synthesis and absolute configuration of the C33-C42 fragment of symbiodinolide

Takamura, H., Kadonaga, Y., Yamano, Y., Han, C., Kadota, I. & Uemura, D., Sep 5 2009, In : Tetrahedron. 65, 36, p. 7449-7456 8 p.

Research output: Contribution to journalArticle

Esters
Stereochemistry
Aspartic Acid
symbiodinolide
ethylene
18 Citations (Scopus)

Synthesis and structural determination of the C33-C42 fragment of symbiodinolide

Takamura, H., Kadonaga, Y., Yamano, Y., Han, C., Aoyama, Y., Kadota, I. & Uemura, D., Feb 25 2009, In : Tetrahedron Letters. 50, 8, p. 863-866 4 p.

Research output: Contribution to journalArticle

Esters
Stereochemistry
Cross Reactions
Macrolides
Aspartic Acid
25 Citations (Scopus)

Synthesis and structural revision of symbiodinolide C23-C34 fragment

Murata, T., Sano, M., Takamura, H., Kadota, I. & Uemura, D., Jul 3 2009, In : Journal of Organic Chemistry. 74, 13, p. 4797-4803 7 p.

Research output: Contribution to journalArticle

Stereochemistry
Aspartic Acid
symbiodinolide
53 Citations (Scopus)

Total synthesis of brevenal

Takamura, H., Kikuchi, S., Nakamura, Y., Yamagami, Y., Kishi, T., Kadota, I. & Yamamoto, Y., Jun 18 2009, In : Organic Letters. 11, 12, p. 2531-2534 4 p.

Research output: Contribution to journalArticle

Ether
ethers
Allylation
metathesis
dienes
2008
9 Citations (Scopus)

A cross-metathesis approach to the stereocontrolled synthesis of the AB ring segment of ciguatoxin

Kadota, I., Abe, T., Uni, M., Takamura, H. & Yamamoto, Y., May 26 2008, In : Tetrahedron Letters. 49, 22, p. 3643-3647 5 p.

Research output: Contribution to journalArticle

Ciguatoxins
Lewis Acids
Cross Reactions
Cyclization
Dehydration
20 Citations (Scopus)

Stereocontrolled synthesis of the C79-C96 fragment of symbiodinolide

Takamura, H., Ando, J., Abe, T., Murata, T., Kadota, I. & Uemura, D., Jul 28 2008, In : Tetrahedron Letters. 49, 31, p. 4626-4629 4 p.

Research output: Contribution to journalArticle

symbiodinolide
2007
21 Citations (Scopus)

Concise synthesis of a highly functionalized cyclopentane segment: toward the total synthesis of kansuinine A

Shimokawa, K., Takamura, H. & Uemura, D., Aug 6 2007, In : Tetrahedron Letters. 48, 32, p. 5623-5625 3 p.

Research output: Contribution to journalArticle

Euphorbia
Cyclopentanes
Diterpenes
Cyclization
Carbon
18 Citations (Scopus)

Studies toward the total synthesis of nakiterpiosin: construction of the CDE ring system by a transannular Diels-Alder strategy

Ito, T., Ito, M., Arimoto, H., Takamura, H. & Uemura, D., Jul 30 2007, In : Tetrahedron Letters. 48, 31, p. 5465-5469 5 p.

Research output: Contribution to journalArticle

Cycloaddition Reaction
nakiterpiosin
2 Citations (Scopus)

Total synthesis of brevetoxin B

Kadota, I. & Takamura, H., May 2007, In : Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry. 65, 5, p. 430-437 8 p.

Research output: Contribution to journalArticle

Allylation
Ethers
Sodium Channels
Tides
Medical problems

ブレベトキシンBの全合成

Takamura, H., 2007, In : 有機合成化学協会誌. 65, p. 430-438 9 p.

Research output: Contribution to journalArticle

2006
14 Citations (Scopus)

Improved synthesis of the A-G ring segment of brevetoxin B

Kadota, I., Nishii, H., Ishioka, H., Takamura, H. & Yamamoto, Y., May 26 2006, In : Journal of Organic Chemistry. 71, 11, p. 4183-4187 5 p.

Research output: Contribution to journalArticle

Allylation
Lewis Acids
Acetals
Alkenes
Ether