• 1908 Citations
  • 26 h-Index
1991 …2020

Research output per year

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Research Output

  • 1908 Citations
  • 26 h-Index
  • 67 Article
  • 1 Comment/debate
  • 1 Short survey
2020
Open Access

Initial phospholipid-dependent Irgb6 targeting to Toxoplasma gondii vacuoles mediates host defense

Lee, Y., Yamada, H., Pradipta, A., Ma, J. S., Okamoto, M., Nagaoka, H., Takashima, E., Standley, D. M., Sasai, M., Takei, K. & Yamamoto, M., 2020, In : Life Science Alliance. 3, 1, e201900549.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
2019

ATP6AP2 variant impairs CNS development and neuronal survival to cause fulminant neurodegeneration

Hirose, T., Cabrera-Socorro, A., Chitayat, D., Lemonnier, T., Féraud, O., Cifuentes-Diaz, C., Gervasi, N., Mombereau, C., Ghosh, T., Stoica, L., d’Arc Al Bacha, J., Yamada, H., Lauterbach, M. A., Guillon, M., Kaneko, K., Norris, J. W., Siriwardena, K., Blasér, S., Teillon, J., Mendoza-Londono, R. & 12 others, Russeau, M., Hadoux, J., Ito, S., Corvol, P., Matheus, M. G., Holden, K. R., Takei, K., Emiliani, V., Bennaceur-Griscelli, A., Schwartz, C. E., Nguyen, G. & Groszer, M., May 1 2019, In : Journal of Clinical Investigation. 129, 5, p. 2145-2162 18 p.

Research output: Contribution to journalArticle

Open Access
8 Citations (Scopus)

Phosphorylation of cortactin by cyclin-dependent kinase 5 modulates actin bundling by the dynamin 1-cortactin ring-like complex and formation of filopodia and lamellipodia in NG108-15 glioma-derived cells

Abe, T., La, T. M., Miyagaki, Y., Oya, E., Wei, F. Y., Sumida, K., Fujise, K., Takeda, T., Tomizawa, K., Takei, K. & Yamada, H., Feb 2019, In : International journal of oncology. 54, 2, p. 550-558 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2018

Dynamic clustering of dynamin-amphiphysin helices regulates membrane constriction and fission coupled with GTP hydrolysis

Takeda, T., Kozai, T., Yang, H., Ishikuro, D., Seyama, K., Kumagai, Y., Abe, T., Yamada, H., Uchihashi, T., Ando, T. & Takei, K., Jan 23 2018, In : eLife. 7, e30246.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2016
19 Citations (Scopus)

Dynamin2 GTPase contributes to invadopodia formation in invasive bladder cancer cells

Zhang, Y., Nolan, M., Yamada, H., Watanabe, M., Nasu, Y., Takei, K. & Takeda, T., Nov 18 2016, In : Biochemical and Biophysical Research Communications. 480, 3, p. 409-414 6 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Expression of a dynamin 2 mutant associated with Charcot-Marie-Tooth disease leads to aberrant actin dynamics and lamellipodia formation

Yamada, H., Kobayashi, K., Zhang, Y., Takeda, T. & Takei, K., Aug 15 2016, In : Neuroscience Letters. 628, p. 179-185 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Fluvoxamine, an anti-depressant, inhibits human glioblastoma invasion by disrupting actin polymerization

Hayashi, K., Michiue, H., Yamada, H., Takata, K., Nakayama, H., Wei, F. Y., Fujimura, A., Tazawa, H., Asai, A., Ogo, N., Miyachi, H., Nishiki, T. I., Tomizawa, K., Takei, K. & Matsui, H., Mar 18 2016, In : Scientific reports. 6, 23372.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Inhibition of SGLT2 alleviates diabetic nephropathy by suppressing high glucose-induced oxidative stress in type 1 diabetic mice

Hatanaka, T., Ogawa, D., Tachibana, H., Eguchi, J., Inoue, T., Yamada, H., Takei, K., Makino, H. & Wada, J., Aug 1 2016, In : Pharmacology Research and Perspectives. 4, 4, e00239.

Research output: Contribution to journalArticle

27 Citations (Scopus)
2015

Possible role of cortactin phosphorylation by protein kinase Cα in actin-bundle formation at growth cone

Yamada, H., Kikuchi, T., Masumoto, T., Wei, F. Y., Abe, T., Takeda, T., Nishiki, T., Tomizawa, K., Watanabe, M., Matsui, H. & Takei, K., Sep 1 2015, In : Biology of the Cell. 107, 9, p. 319-330 12 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2014

Long-term treatment with the sodium glucose cotransporter 2 inhibitor, dapagliflozin, ameliorates glucose homeostasis and diabetic nephropathy in db/db mice

Terami, N., Ogawa, D., Tachibana, H., Hatanaka, T., Wada, J., Nakatsuka, A., Eguchi, J., Sato Horiguchi, C., Nishii, N., Yamada, H., Takei, K. & Makino, H., Jun 24 2014, In : PloS one. 9, 6, e100777.

Research output: Contribution to journalArticle

149 Citations (Scopus)

Metallothionein deficiency exacerbates diabetic nephropathy in streptozotocin-induced diabetic mice

Tachibana, H., Ogawa, D., Sogawa, N., Asanuma, M., Miyazaki, I., Terami, N., Hatanaka, T., Horiguchi, C. S., Nakatsuka, A., Eguchi, J., Wada, J., Yamada, H., Takei, K. & Makino, H., Jan 1 2014, In : American Journal of Physiology - Renal Physiology. 306, 1, p. F105-F115

Research output: Contribution to journalArticle

15 Citations (Scopus)
12 Citations (Scopus)

Stabilization of actin bundles by a Dynamin 1/cortactin ring complex is necessary for growth cone filopodia

Yamada, H., Abe, T., Satoh, A., Okazaki, N., Tago, S., Kobayashi, K., Yoshida, Y., Oda, Y., Watanabe, M., Tomizawa, K., Matsui, H. & Takei, K., Mar 6 2013, In : Journal of Neuroscience. 33, 10, p. 4514-4526 13 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)
2012

A novel gene expression system for detecting viable bladder cancer cells

Ueki, H., Watanabe, M., Kaku, H., Huang, P., Li, S. A., Ochiai, K., Hirata, T., Noguchi, H., Yamada, H., Takei, K., Nasu, Y., Kashiwakura, Y. & Kumon, H., Jul 2012, In : International journal of oncology. 41, 1, p. 135-140 6 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

REIC/Dkk-3-encoding adenoviral vector as a potentially effective therapeutic agent for bladder cancer

Hirata, T., Watanabe, M., Kaku, H., Kobayashi, Y., Yamada, H., Sakaguchi, M., Takei, K., Huh, N. H., Nasu, Y. & Kumon, H., Aug 2012, In : International journal of oncology. 41, 2, p. 559-564 6 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
2010

Expression pattern of REIC/Dkk-3 in various cell types and the implications of the soluble form in prostatic acinar development

Zhang, K., Watanabe, M., Kashiwakura, Y., Li, S. A., Edamura, K., Huang, P., Yamaguchi, K., Nasu, Y., Kobayashi, Y., Sakaguchi, M., Ochiai, K., Yamada, H., Takei, K., Ueki, H., Huh, N. H., Li, M., Kaku, H., Na, Y. & Kumon, H., Dec 2010, In : International journal of oncology. 37, 6, p. 1495-1501 7 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Use of liposomes to study vesicular transport.

Takei, K., Yamada, H. & Abe, T., 2010, In : Methods in molecular biology (Clifton, N.J.). 606, p. 531-542 12 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2009

Dynamic interaction of amphiphysin with N-WASP regulates actin assembly

Yamada, H., Padilla-Parra, S., Park, S. J., Itoh, T., Chaineau, M., Monaldi, I., Cremona, O., Benfenati, F., De Camilli, P., Coppey-Moisan, M., Tramier, M., Galli, T. & Takei, K., Dec 4 2009, In : Journal of Biological Chemistry. 284, 49, p. 34244-34256 13 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)

Dynamin 2 is required for actin assembly in phagocytosis in Sertoli cells

Otsuka, A., Abe, T., Watanabe, M., Yagisawa, H., Takei, K. & Yamada, H., Jan 16 2009, In : Biochemical and Biophysical Research Communications. 378, 3, p. 478-482 5 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Dynasore, a dynamin inhibitor, suppresses lamellipodia formation and cancer cell invasion by destabilizing actin filaments

Yamada, H., Abe, T., Li, S. A., Masuoka, Y., Isoda, M., Watanabe, M., Nasu, Y., Kumon, H., Asai, A. & Takei, K., Dec 25 2009, In : Biochemical and Biophysical Research Communications. 390, 4, p. 1142-1148 7 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)
2008

Dynamin 2 cooperates with amphiphysin 1 in phagocytosis in Sertoli cells

Nakanishi, A., Abe, T., Watanabe, M., Takei, K. & Yamada, H., Dec 2008, In : Acta medica Okayama. 62, 6, 5.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2007

Amphiphysin 1 is important for actin polymerization during phagocytosis

Yamada, H., Ohashi, E., Abe, T., Kusumi, N., Li, S. A., Yoshida, Y., Watanabe, M., Tomizawa, K., Kashiwakura, Y., Kumon, H., Matsui, H. & Takei, K., Nov 2007, In : Molecular Biology of the Cell. 18, 11, p. 4669-4680 12 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Amphiphysin 1 participates in phagocytosis by stimulating actin polymerization.(共著)

Yamada, H., 2007, In : Molecular Biology of the Cell. 18, 11, p. 4669-4680 12 p.

Research output: Contribution to journalArticle

Identification of Vanabin-interacting protein 1 (VIP1) from blood cells of the vanadium-rich ascidian Ascidia sydneiensis samea

Ueki, T., Shintaku, K., Yonekawa, Y., Takatsu, N., Yamada, H., Hamada, T., Hirota, H. & Michibata, H., Jun 2007, In : Biochimica et Biophysica Acta - General Subjects. 1770, 6, p. 951-957 7 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Implication of amphiphysin 1 and dynamin 2 in tubulobulbar complex formation and spermatid release

Kusumi, N., Watanabe, M., Yamada, H., Li, S. A., Kashiwakura, Y., Matsukawa, T., Nagai, A., Nasu, Y., Kumon, H. & Takei, K., 2007, In : Cell structure and function. 32, 2, p. 101-113 13 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Major Cdk5-dependent phosphorylation sites of amphiphysin 1 are implicated in the regulation of the membrane binding and endocytosis

Liang, S., Wei, F. Y., Wu, Y. M., Tanabe, K., Abe, T., Oda, Y., Yoshida, Y., Yamada, H., Matsui, H., Tomizawa, K. & Takei, K., Sep 2007, In : Journal of Neurochemistry. 102, 5, p. 1466-1476 11 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
2006

Localization of Vanabins, vanadium-binding proteins, in the blood cells of the vanadium-rich ascidian, Ascidia sydneiensis samea

Yamaguchi, N., Amakawa, Y., Yamada, H., Ueki, T. & Michibata, H., Oct 2006, In : Zoological science. 23, 10, p. 909-915 7 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2005

Regulatory mechanisms of dynamin-dependent endocytosis

Takei, K., Yoshida, Y. & Yamada, H., Mar 2005, In : Journal of biochemistry. 137, 3, p. 243-247 5 p.

Research output: Contribution to journalShort survey

61 Citations (Scopus)
2004

Dynamin-2 regulates oxidized low-density lipoprotein-induced apoptosis of vascular smooth muscle cell

Kashiwakura, Y., Watanabe, M., Kusumi, N., Sumiyoshi, K., Nasu, Y., Yamada, H., Sawamura, T., Kumon, H., Takei, K. & Daida, H., Nov 23 2004, In : Circulation. 110, 21, p. 3329-3334 6 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Immunohistochemical localization of Klotho protein in brain, kidney, and reproductive organs of mice

Li, S. A., Watanabe, M., Yamada, H., Nagai, A., Kinuta, M. & Takei, K., Dec 2004, In : Cell structure and function. 29, 4, p. 91-99 9 p.

Research output: Contribution to journalArticle

239 Citations (Scopus)
2003

Formation of S-[2-carboxy-1-(1H-imidazol-4-yl) ethyl]glutathione, a new metabolite of L-histidine, from cis-urocanic acid and glutathione by the action of glutathione S-transferase

Kinuta, M., Kinuta, K., Yamada, H., Abe, T., Yoshida, Y., Araki, K., Li, S. A., Otsuka, A., Nakanishi, A., Moriyama, Y. & Takei, K., Sep 2003, In : ELECTROPHORESIS. 24, 18, p. 3212-3218 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Secretory granule-mediated co-secretion of L-glutamate and glucagon triggers glutamatergic signal transmission in islets of Langerhans

Hayashi, M., Yamada, H., Uehara, S., Morimoto, R., Muroyama, A., Yatsushiro, S., Takeda, J., Yamamoto, A. & Moriyama, Y., Jan 17 2003, In : Journal of Biological Chemistry. 278, 3, p. 1966-1974 9 p.

Research output: Contribution to journalArticle

107 Citations (Scopus)
2002

Distribution of dynamins in testis and their possible relation to spermatogenesis

Kamitani, A., Yamada, H., Kinuta, M., Watanabe, M., Li, S. A., Matsukawa, T., McNiven, M., Kumon, H. & Takei, K., Jan 1 2002, In : Biochemical and Biophysical Research Communications. 294, 2, p. 261-267 7 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Norepinephrine triggers Ca2+-dependent exocytosis of 5-hydroxytryptamine from rat pinealocytes in culture

Yamada, H., Hayashi, M., Uehara, S., Kinoshita, M., Muroyama, A., Watanabe, M., Takei, K. & Moriyama, Y., 2002, In : Journal of Neurochemistry. 81, 3, p. 533-540 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Phosphatidylinositol 4,5-bisphosphate stimulates vesicle formation from liposomes by brain cytosol

Kinuta, M., Yamada, H., Abe, T., Watanabe, M., Li, S. A., Kamitani, A., Yasuda, T., Matsukawa, T., Kumon, H. & Takei, K., Mar 5 2002, In : Proceedings of the National Academy of Sciences of the United States of America. 99, 5, p. 2842-2847 6 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)
2001

Ca2+-dependent exocytosis of L-glutamate by αTC6, clonal mouse pancreatic α-cells

Yamada, H., Otsuka, M., Hayashi, M., Nakatsuka, S., Hamaguchi, K., Yamamoto, A. & Moriyama, Y., 2001, In : Diabetes. 50, 5, p. 1012-1020 9 p.

Research output: Contribution to journalArticle

Open Access
33 Citations (Scopus)

D-Aspartate is Stored in Secretory Granules and Released through a Ca 2+-dependent Pathway in a Subset of Rat Pheochromocytoma PC12 Cells

Nakatsuka, S., Hayashi, M., Muroyama, A., Otsuka, M., Kozaki, S., Yamada, H. & Moriyama, Y., Jul 13 2001, In : Journal of Biological Chemistry. 276, 28, p. 26589-26596 8 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)

Determination of S-[2-carboxy-1-(1H-imidazol-4-yl)ethyl]glutathione, a novel metabolite of L-histidine, in tissue extracts from sunlight-irradiated rat by capillary electrophoresis

Kinuta, M., Ohta, J., Yamada, H., Kinuta, K., Abe, T., Li, S. A., Otsuka, A., Nakanishi, A. & Takei, K., 2001, In : ELECTROPHORESIS. 22, 16, p. 3365-3370 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Identification and Characterization of a Synaptojanin 2 Splice Isoform Predominantly Expressed in Nerve Terminals

Nemoto, Y., Wenk, M. R., Watanabe, M., Daniell, L., Murakami, T., Ringstad, N., Yamada, H., Takei, K. & De Camilli, P., Nov 2 2001, In : Journal of Biological Chemistry. 276, 44, p. 41133-41142 10 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)
2000

AMPA triggers glutamate exocytosis via ionotropic glutamate receptors expressed in rat pinealocytes.

Yamada, H., 2000, In : J. Neurochem.. 75, p. 288-297 10 p.

Research output: Contribution to journalArticle

Ionotropic glutamate receptors expressed in human retinoblastoma Y79 cells

Takeda, M., Haga, M., Yamada, H., Kinoshita, M., Otsuka, M., Tsuboi, S. & Moriyama, Y., Nov 17 2000, In : Neuroscience Letters. 294, 2, p. 97-100 4 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Ionotropic glutamate receptors trigger microvesicle-mediated exocytosis of L-glutamate in rat pinealocytes

Yatsushiro, S., Yamada, H., Hayashi, M., Yamamoto, A. & Moriyama, Y., 2000, In : Journal of Neurochemistry. 75, 1, p. 288-297 10 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Synaptic-like microvesicles, synaptic vesicle counterparts in endocrine cells, are involved in a novel regulatory mechanism for the synthesis and secretion of hormones

Moriyama, Y., Hayashi, M., Yamada, H., Yatsushiro, S., Ishio, S. & Yamamoto, A., Jan 2000, In : Journal of Experimental Biology. 203, 1, p. 117-125 9 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)

Vacuolar H+-ATPase localized in plasma membranes of malaria parasite cells, Plasmodium falciparum, is involved in regional acidification of parasitized erythrocytes

Hayashi, M., Yamada, H., Mitamura, T., Horii, T., Yamamoto, A. & Moriyama, Y., Nov 3 2000, In : Journal of Biological Chemistry. 275, 44, p. 34353-34358 6 p.

Research output: Contribution to journalArticle

84 Citations (Scopus)