• 692 Citations
  • 14 h-Index
1991 …2018

Research output per year

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Research Output

  • 692 Citations
  • 14 h-Index
  • 43 Article
  • 2 Editorial
  • 1 Review article
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Article
2018

Administration of kampo medicine through a tube at an advanced critical care center

Niimura, T., Zamami, Y., Imai, T., Ito, T., Sagara, H., Hiroyuki, H., Esumi, S., Takechi, K., Imanishi, M., Koyama, T., Amano, M., Kurata, N., Kitamura, Y., Nakura, H., Sendo, T. & Ishizawa, K., 2018, In : Journal of Medical Investigation. 65, 1-2, p. 32-36 5 p.

Research output: Contribution to journalArticle

Evaluation of the benefits of de-escalation for patients with sepsis in the emergency intensive care unit

Niimura, T., Zamami, Y., Imai, T., Nagao, K., Kayano, M., Sagara, H., Goda, M., Okada, N., Chuma, M., Takechi, K., Imanishi, M., Koyama, T., Koga, T., Nakura, H., Sendo, T. & Ishizawa, K., Feb 13 2018, In : Journal of Pharmacy and Pharmaceutical Sciences. 21, 1, p. 54-59 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2017

Meta-analysis of the efficacies of amiodarone and nifekalant in shock-resistant ventricular fibrillation and pulseless ventricular tachycardia

Sato, S., Zamami, Y., Imai, T., Tanaka, S., Koyama, T., Niimura, T., Chuma, M., Koga, T., Takechi, K., Kurata, Y., Kondo, Y., Izawa-Ishizawa, Y., Sendo, T., Nakura, H. & Ishizawa, K., Dec 1 2017, In : Scientific reports. 7, 1, 12683.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2014

Role of pharmacists in disaster medicine: Required knowledge and skills

Nakura, H., Jan 9 2014, In : Yakugaku Zasshi. 134, 1, p. 3-6 4 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2012

Clinical Usefulness of the New Japanese Glomerular Filtration Rate Equation for Initial and Individualized Dosage Adjustment Concentrations of Vancomycin

Kuroda, N., Ueshima, S., Sato, T., Kobiki, E., Kawasaki, Y., Matsunaga, H., Nakura, H. & Sendo, T., 2012, In : Yakugaku Zasshi. 132, 1, p. 125-133 9 p.

Research output: Contribution to journalArticle

2011

Regio- and stereoselective oxidation of propranolol enantiomers by human CYP2D6, cynomolgus monkey CYP2D17 and marmoset CYP2D19

Narimatsu, S., Nakata, T., Shimizudani, T., Nagaoka, K., Nakura, H., Masuda, K., Katsu, T., Koeda, A., Naito, S., Yamano, S., Miyata, A. & Hanioka, N., Feb 1 2011, In : Chemico-Biological Interactions. 189, 3, p. 146-152 7 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2009

Separate evaluation of intestinal and hepatic metabolism of three benzodiazepines in rats with cannulated portal and jugular veins: Comparison with the profile in non-cannulated mice

Kuze, J., Mutoh, T., Takenaka, T., Morisaki, K., Nakura, H., Hanioka, N. & Narimatsu, S., Nov 1 2009, In : Xenobiotica. 39, 11, p. 871-880 10 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

The mechanism causing the difference in kinetic properties between rat CYP2D4 and human CYP2D6 in the oxidation of dextromethorphan and bufuralol

Narimatsu, S., Kazamori, D., Masuda, K., Katsu, T., Funae, Y., Naito, S., Nakura, H., Yamano, S. & Hanioka, N., Mar 1 2009, In : Biochemical Pharmacology. 77, 5, p. 920-931 12 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2008

Toxin production by Aeromonas sobria in natural environments: River water vs. seawater

Khan, R., Takahashi, E., Nakura, H., Ansaruzzaman, M., Banik, S., Ramamurthy, T. & Okamoto, K., Dec 2008, In : Acta medica Okayama. 62, 6, 2.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2002

Total analysis and purification of cellular proteins binding to cisplatin-damaged DNA using submicron beads

Tomohiro, T., Sawada, J. I., Sawa, C., Nakura, H., Yoshida, S., Kodaka, M., Hatakeyama, M., Kawaguchi, H., Handa, H. & Okuno, H., Apr 13 2002, In : Bioconjugate Chemistry. 13, 2, p. 163-166 4 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)
2001

CYP3A activity in European American and Japanese men using midazolam as an in vivo probe

Tateishi, T., Watanabe, M., Nakura, H., Asoh, M., Shirai, H., Mizorogi, Y., Kobayashi, S., Thummel, K. E. & Wilkinson, G. R., May 1 2001, In : Clinical Pharmacology and Therapeutics. 69, 5, p. 333-339 7 p.

Research output: Contribution to journalArticle

72 Citations (Scopus)
1999

Carbamazepine induces multiple cytochrome P450 subfamilies in rats

Tateishi, T., Asoh, M., Nakura, H., Watanabe, M., Tanaka, M., Kumai, T. & Kobayashi, S., Feb 12 1999, In : Chemico-Biological Interactions. 117, 3, p. 257-268 12 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)

Dihydropyrimidine dehydrogenase activity and fluorouracil pharmacokinetics with liver damage induced by bile duct ligation in rats

Tateishi, T., Watanabe, M., Nakura, H., Tanaka, M., Kumai, T., Sakata, S. F., Tamaki, N., Ogura, K., Nishiyama, T., Watabe, T. & Kobayashi, S., Jun 9 1999, In : Drug Metabolism and Disposition. 27, 6, p. 651-654 4 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Frequency of immediate-type food allergy in children in Japan

Iikura, Y., Imai, Y., Imai, T., Akasawa, A., Fujita, K., Hoshiyama, K., Nakura, H., Kohno, Y., Koike, K., Okudaira, H. & Iwasaki, E., Jan 1 1999, In : International Archives of Allergy and Immunology. 118, 2-4, p. 251-252 2 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)

Multiple cytochrome P-450 subfamilies are co-induced with P-glycoprotein by both phenothiazine and 2-acetylaminofluorene in rats

Tateishi, T., Nakura, H., Asoh, M., Watanabe, M., Tanaka, M., Kumai, T. & Kobayashi, S., Apr 26 1999, In : Cancer Letters. 138, 1-2, p. 73-79 7 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Role of CYP3A in haloperidol N-dealkylation and pharmacokinetics in rats

Watanabe, M., Tateishi, T., Asoh, M., Nakura, H., Tanaka, M., Kumai, T. & Kobayashi, S., Jan 1 1999, In : Fundamental and Clinical Pharmacology. 13, 3, p. 337-342 6 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Ticlopidine decreases the in vivo activity of CYP2C19 as measured by omeprazole metabolism

Tateishi, T., Kumai, T., Watanabe, M., Nakura, H., Tanaka, M. & Kobayashi, S., Apr 16 1999, In : British Journal of Clinical Pharmacology. 47, 4, p. 454-457 4 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Ursodeoxycholic acid prevents hepatic cytochrome P450 isozyme reduction in rats with deoxycholic acid-induced liver injury

Tanaka, M., Nakura, H., Tateishi, T., Watanabe, M., Nakaya, S., Kumai, T. & Kobayashi, S., Aug 1999, In : Journal of Hepatology. 31, 2, p. 263-270 8 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
1998

A comparison of the inhibitory effects of four volatile anaesthetics on the metabolism of chlorzoxazone, a substrate for CYP2E1, in rabbits

Tateishi, T., Watanabe, M., Nakura, H., Tanaka, M., Kumai, T., Aoki, T. & Kobayashi, S., Jan 1 1998, In : Acta Anaesthesiologica Scandinavica. 42, 9, p. 1028-1032 5 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Effect of hypoalbuminemia on the disposition of theophylline: Comparative study with Sprague-Dawley rats and a mutant Sprague-Dawley hyperlipidemic strain with hypoalbuminemia

Nakura, H., Tateishi, T., Watanabe, M., Asoh, M., Tanaka, M., Kumai, T. & Kobayashi, S., Jun 1 1998, In : Drug Metabolism and Disposition. 26, 6, p. 595-597 3 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Effects of anti-androgen treatment on the catecholamine synthetic pathway in the adrenal medulla of spontaneously hypertensive rats

Kumai, T., Tanaka, M., Tateishi, T., Watanabe, M., Nakura, H., Asoh, M. & Kobayashi, S., Jul 16 1998, In : Naunyn-Schmiedeberg's Archives of Pharmacology. 357, 6, p. 620-624 5 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Effects of glucocorticoids on pharmacokinetics and pharmacodynamics of midazolam in rats

Watanabe, M., Tateishi, T., Asoh, M., Nakura, H., Tanaka, M., Kumai, T. & Kobayashi, S., Oct 2 1998, In : Life Sciences. 63, 19, p. 1685-1692 8 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Liver damage induced by bile duct ligation affects CYP isoenzymes differently in rats

Tateishi, T., Watanabe, M., Nakura, H., Tanaka, M., Kumai, T. & Kobayashi, S., Jan 1 1998, In : Pharmacology and Toxicology. 82, 2, p. 89-92 4 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Reduced hepatic expression of CYP7A1 and CYP2C13 in rats with spontaneous hyperlipidaemia

Brassil, P. J., Debri, K., Nakura, H., Kobayashi, S., Davies, D. S. & Edwards, R. J., Jul 15 1998, In : Biochemical Pharmacology. 56, 2, p. 253-257 5 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
1997

A comparison of hepatic cytochrome P450 protein expression between infancy and postinfancy

Tateishi, T., Nakura, H., Asoh, M., Watanabe, M., Tanaka, M., Kumai, T., Takashima, S., Imaoka, S., Funae, Y., Yabusaki, Y., Kamataki, T. & Kobayashi, S., Nov 21 1997, In : Life Sciences. 61, 26, p. 2567-2574 8 p.

Research output: Contribution to journalArticle

115 Citations (Scopus)

Effects of sodium nitroprusside on the catecholamine levels in the adrenal medulla of spontaneously hypertensive rats

Kumai, T., Tanaka, M., Tateishi, T., Watanabe, M., Nakura, H., Asoh, M. & Kobayashi, S., Jan 1 1997, In : Japanese Heart Journal. 38, 4, 1 p.

Research output: Contribution to journalArticle

Open Access

Effects of the estrous cycle and the gender difference on hepatic drug-metabolising enzyme activities

Watanabe, M., Tanaka, M., Tateishi, T., Nakura, H., Kumai, T. & Kobayashi, S., May 1997, In : Pharmacological Research. 35, 5, p. 477-480 4 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Enhancement of the affinity of androgen receptor in the adrenal medulla of spontaneously hypertensive rats

Kumai, T., Tanaka, M., Tateishi, T., Watanabe, M., Nakura, H. & Kobayashi, S., Nov 1997, In : Clinical and Experimental Hypertension. 19, 8, p. 1179-1191 13 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Halothane inhalation inhibits the metabolism of chlorzoxazone, a substrate for CYP2E1, in rabbits

Tateishi, T., Watanabe, M., Nakura, H., Tanaka, M., Kumai, T., Aoki, T. & Kobayashi, S., Aug 26 1997, In : Anesthesia and Analgesia. 85, 1, p. 199-203 5 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Opposite effects of isoniazid and fasting on the expression of CYP2E1 protein and mRNA in house musk shrew (Suncus murinus)

Nakura, H., Itoh, S., Kusano, H., Ishizone, H. & Kamataki, T., Feb 1997, In : Biochemistry and Molecular Biology International. 41, 2, p. 293-301 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Sex- or age-related differences were not detected in the activity of dihydropyrimidine dehydrogenase from rat liver

Tateishi, T., Watanabe, M., Nakura, H., Tanaka, M., Kumai, T. & Kobayashi, S., Feb 1997, In : Pharmacological Research. 35, 2, p. 103-106 4 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

The effects of streptozotocin-induced hypoinsulinemia on serum lipid levels in spontaneously hyperlipidemic rats

Nakura, H., Tanaka, M., Tateishi, T., Watanabe, M., Kumai, T. & Kobayashi, S., Jan 1 1997, In : Hormone and Metabolic Research. 29, 9, p. 454-457 4 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
1996

A cardiotonic steroid bufalin-induced differentiation of THP-1 cells. Involvement of Na+, K+-ATPase inhibition in the early changes in proto-oncogene expression

Numazawa, S., Inoue, N., Nakura, H., Sugiyama, T., Fujino, E., Shinoki, M. A., Yoshida, T. & Kuroiwa, Y., Jul 26 1996, In : Biochemical Pharmacology. 52, 2, p. 321-329 9 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Elevated tyrosine hydroxylase nRNA levels in medulla oblongata of spontaneously hypertensive rats

Kumai, T., Tanaka, M., Watanabe, M., Nakura, H., Tateishi, T. & Kobayashi, S., Feb 1996, In : Molecular Brain Research. 36, 1, p. 197-199 3 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Preliminary examination of the influence of incubation time or cytosolic protein concentration on dihydropyrimidine dehydrogenase activity

Tateishi, T., Nakura, H., Watanabe, M., Tanaka, M., Kumai, T. & Kobayashi, S., Aug 15 1996, In : Clinica Chimica Acta. 252, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Reduced hepatic drug-metabolising enzyme activities in spontaneously hyperlipidaemic rat as an animal model of hypercholesterolaemia

Watanabe, M., Nakura, H., Tateishi, T., Tanaka, M., Kumai, T. & Kobayashi, S., Jun 3 1996, In : Medical Science Research. 24, 4, p. 257-259 3 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

The activity of dihydropyrimidine dehydrogenase from rat liver was not affected by any of five 5-hydroxytryptamine antagonists

Tateishi, T., Nakura, H., Watanabe, M., Tanaka, M., Kumai, T. & Kobayashi, S., Nov 12 1996, In : Cancer Letters. 108, 1, p. 1-5 5 p.

Research output: Contribution to journalArticle

1995

Effects of submaxillariectomy on ovarian androgen and estrogen production in adult female rats

Tanaka, M., Watanabe, M., Kumai, T., Nakura, H. & Kobayashi, S., Jan 1 1995, In : Biochemical and Biophysical Research Communications. 213, 2, p. 550-554 5 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Evidence for the lack of hepatic n-acetyltransferase in suncus (Suncus murinus)

Nakura, H., Itoh, S., Kusano, H., Ishizone, H., Deguchi, T. & Kamataki, T., Oct 12 1995, In : Biochemical Pharmacology. 50, 8, p. 1165-1170 6 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Influence of androgen on tyrosine hydroxylase mRNA in adrenal medulla of spontaneously hypertensive rats

Kumai, T., Tanaka, M., Watanabe, M., Nakura, H. & Kobayashi, S., Jul 1995, In : Hypertension. 26, 1, p. 208-212 5 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)
1994

Activities of drug-metabolizing enzymes in the liver of suncus murinus: Possible lack of n-acetyltransferase activity in liver cytosol

Nakura, H., Itoh, S., Kusano, H., Ishizone, H. & Kamataki, T., Jan 1 1994, In : Pharmacology. 48, 3, p. 201-204 4 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
1992

Decrease in the content of cytochrome P450IIE by fasting in liver microsomes of house musk shrew (Suncus murinus)

Nakura, H., Itoh, S., Kusano, H., Ishizone, H., Imaoka, S., Funae, Y., Yokoi, T. & Kamataki, T., May 8 1992, In : Biochemical Pharmacology. 43, 9, p. 1907-1910 4 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
1991

Formation of an Antibacterial Metabolite from a New Macrolide Compound 23-0-Benzyl-5-mycaminosyl-tylonolide (TMC-101), by a Hepatic Microsomal Drug-Metabolizing Enzyme System

Nakura, H., Ohi, H., Miura, T., Fujiwara, T., Ishizone, H., Yokoi, T., Kitada, M. & Kamataki, T., Jan 1991, In : journal of pharmacobio-dynamics. 14, 7, p. 377-383 7 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)