• 757 Citations
  • 17 h-Index
20002020

Research output per year

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Research Output

  • 757 Citations
  • 17 h-Index
  • 54 Article
  • 1 Review article
2020
Open Access
2 Citations (Scopus)

Inhibitory effect of retinoic acid receptor agonists on in vitro chondrogenic differentiation

Sumitani, Y., Uchibe, K., Yoshida, K., Weng, Y., Guo, J., Yuan, H., Ikegame, M., Kamioka, H. & Okamura, H., Mar 1 2020, In : Anatomical Science International. 95, 2, p. 202-208 7 p.

Research output: Contribution to journalArticle

Outer membrane vesicles of Porphyromonas gingivalis attenuate insulin sensitivity by delivering gingipains to the liver

Seyama, M., Yoshida, K., Yoshida, K., Fujiwara, N., Ono, K., Eguchi, T., Kawai, H., Guo, J., Weng, Y., Haoze, Y., Uchibe, K., Ikegame, M., Sasaki, A., Nagatsuka, H., Okamoto, K., Okamura, H. & Ozaki, K., Jun 1 2020, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1866, 6, 165731.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Quorum sensing molecule N-(3-oxododecanoyl)-L-homoserine lactone: An all-rounder in mammalian cell modification

Guo, J., Yoshida, K., Ikegame, M. & Okamura, H., Mar 2020, In : journal of oral biosciences. 62, 1, p. 16-29 14 p.

Research output: Contribution to journalReview article

Open Access
1 Citation (Scopus)
Open Access
1 Citation (Scopus)
2019
1 Citation (Scopus)
2018

Organoids with cancer stem cell-like properties secrete exosomes and HSP90 in a 3D nanoenvironment

Eguchi, T., Sogawa, C., Okusha, Y., Uchibe, K., Iinuma, R., Ono, K., Nakano, K., Murakami, J., Itoh, M., Arai, K., Fujiwara, T., Namba, Y., Murata, Y., Ohyama, K., Shimomura, M., Okamura, H., Takigawa, M., Nakatsura, T., Kozaki, K. I., Okamoto, K. & 1 others, Calderwood, S. K., Feb 2018, In : PloS one. 13, 2, e0191109.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Reduction of protein phosphatase 2A Cα promotes in vivo bone formation and adipocyte differentiation

Yoshida, K., Teramachi, J., Uchibe, K., Ikegame, M., Qiu, L., Yang, D. & Okamura, H., Jul 15 2018, In : Molecular and cellular endocrinology. 470, p. 251-258 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
4 Citations (Scopus)
2017

Involvement of interleukin-23 induced by Porphyromonas endodontalis lipopolysaccharide in osteoclastogenesis

Ma, N., Yang, D., Okamura, H., Teramachi, J., Hasegawa, T., Qiu, L. & Haneji, T., Feb 2017, In : Molecular Medicine Reports. 15, 2, p. 559-566 8 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

PKR induces the expression of NLRP3 by regulating the NF-κB pathway in Porphyromonas gingivalis-infected osteoblasts

Yoshida, K., Okamura, H., Hiroshima, Y., Abe, K., Kido, J. I., Shinohara, Y. & Ozaki, K., May 1 2017, In : Experimental Cell Research. 354, 1, p. 57-64 8 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

PKR regulates LPS-induced osteoclast formation and bone destruction in vitro and in vivo

Teramachi, J., Inagaki, Y., Shinohara, H., Okamura, H., Yang, D., Ochiai, K., Baba, R., Morimoto, H., Nagata, T. & Haneji, T., Mar 1 2017, In : Oral Diseases. 23, 2, p. 181-188 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2016

Histone demethylase Jmjd3 regulates osteoblast apoptosis through targeting anti-apoptotic protein Bcl-2 and pro-apoptotic protein Bim

Yang, D., Okamura, H., Teramachi, J. & Haneji, T., Apr 1 2016, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1863, 4, p. 650-659 10 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Porphyromonas gingivalis attenuates the insulin-induced phosphorylation and translocation of forkhead box protein O1 in human hepatocytes

Takamura, H., Yoshida, K., Okamura, H., Fujiwara, N. & Ozaki, K., Sep 1 2016, In : Archives of Oral Biology. 69, p. 19-24 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Protein phosphatase 2A Cα regulates proliferation, migration, and metastasis of osteosarcoma cells

Yang, D., Okamura, H., Morimoto, H., Teramachi, J. & Haneji, T., Oct 1 2016, In : Laboratory Investigation. 96, 10, p. 1050-1062 13 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2015

Double Stranded RNA-Dependent Protein Kinase is Necessary for TNF-α-Induced Osteoclast Formation in Vitro and in Vivo

Shinohara, H., Teramachi, J., Okamura, H., Yang, D., Nagata, T. & Haneji, T., Sep 1 2015, In : Journal of Cellular Biochemistry. 116, 9, p. 1957-1967 11 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Histone Demethylase Utx Regulates Differentiation and Mineralization in Osteoblasts

Yang, D., Okamura, H., Teramachi, J. & Haneji, T., Nov 1 2015, In : Journal of Cellular Biochemistry. 116, 11, p. 2628-2636 9 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2014

Calcium hydroxide suppresses Porphyromonas endodontalis lipopolysaccharide-induced bone destruction

Guo, J., Yang, D., Okamura, H., Teramachi, J., Ochiai, K., Qiu, L. & Haneji, T., May 2014, In : Journal of dental research. 93, 5, p. 508-513 6 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Preventive effect of daiokanzoto (tj-84) on 5-Fluorouracil-Induced human gingival cell death through the inhibition of reactive oxygen species production

Yoshida, K., Yoshioka, M., Okamura, H., Moriyama, S., Kawazoe, K., Grenier, D. & Hinode, D., Nov 12 2014, In : PloS one. 9, 11, e112689.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Reduction of PP2A Cα stimulates adipogenesis by regulating the Wnt/GSK-3β/β-catenin pathway and PPARγ expression

Okamura, H., Yang, D., Yoshida, K., Teramachi, J. & Haneji, T., Nov 2014, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1843, 11, p. 2376-2384 9 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Tumor necrosis factor-α induces interleukin-34 expression through nuclear factor-κB activation in MC3T3-E1 osteoblastic cells

Yu, Y., Yang, D., Qiu, L., Okamura, H., Guo, J. & Haneji, T., Sep 2014, In : Molecular Medicine Reports. 10, 3, p. 1371-1376 6 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)
2013

Histone demethylase Jmjd3 regulates osteoblast differentiation via transcription factors Runx2 and osterix

Yang, D., Okamura, H., Nakashima, Y. & Haneji, T., Nov 22 2013, In : Journal of Biological Chemistry. 288, 47, p. 33530-33541 12 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)

Oral Porphyromonas gingivalis translocates to the liver and regulates hepatic glycogen synthesis through the Akt/GSK-3β signaling pathway

Ishikawa, M., Yoshida, K., Okamura, H., Ochiai, K., Takamura, H., Fujiwara, N. & Ozaki, K., Dec 1 2013, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1832, 12, p. 2035-2043 9 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Protein phosphatase 2A Cα is involved in osteoclastogenesis by regulating RANKL and OPG expression in osteoblasts

Okamura, H., Yang, D., Yoshida, K. & Haneji, T., Jan 4 2013, In : FEBS Letters. 587, 1, p. 48-53 6 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Protein phosphatase 2A Cα regulates osteoblast differentiation and the expressions of bone sialoprotein and osteocalcin via osterix transcription factor

Okamura, H., Yoshida, K., Yang, D. & Haneji, T., May 1 2013, In : Journal of cellular physiology. 228, 5, p. 1031-1037 7 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
2012

Interaction between PKR and PACT mediated by LPS-inducible NF-κB in human gingival cells

Yoshida, K., Okamura, H., Hoshino, Y., Shono, M., Yoshioka, M., Hinode, D. & Yoshida, H., Jan 1 2012, In : Journal of Cellular Biochemistry. 113, 1, p. 165-173 9 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

PKR plays a positive role in osteoblast differentiation by regulating GSK-3β activity through a β-catenin-independent pathway

Yoshida, K., Okamura, H., Ochiai, K., Hoshino, Y., Haneji, T., Yoshioka, M., Hinode, D. & Yoshida, H., Sep 25 2012, In : Molecular and cellular endocrinology. 361, 1-2, p. 99-105 7 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2011

Intermedilysin induces EGR-1 expression through calcineurin/NFAT pathway in human cholangiocellular carcinoma cells

Susilowati, H., Okamura, H., Hirota, K., Shono, M., Yoshida, K., Murakami, K., Tabata, A., Nagamune, H., Haneji, T. & Miyake, Y., Jan 7 2011, In : Biochemical and Biophysical Research Communications. 404, 1, p. 57-61 5 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Reduction of protein phosphatase 2A Cα enhances bone formation and osteoblast differentiation through the expression of bone-specific transcription factor Osterix

Okamura, H., Yoshida, K., Ochiai, K. & Haneji, T., Sep 1 2011, In : Bone. 49, 3, p. 368-375 8 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
2009

Calcineurin regulates phosphorylation status of transcription factor osterix

Okamura, H., Amorim, B. R., Wang, J., Yoshida, K. & Haneji, T., Feb 6 2009, In : Biochemical and Biophysical Research Communications. 379, 2, p. 440-444 5 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Negative regulation of TIMP1 is mediated by transcription factor TWIST1

Okamura, H., Yoshida, K. & Haneji, T., Jul 3 2009, In : International journal of oncology. 35, 1, p. 181-186 6 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

PKR-mediated degradation of STAT1 regulates osteoblast differentiation

Yoshida, K., Okamura, H., Amorim, B. R., Hinode, D., Yoshida, H. & Haneji, T., Jul 15 2009, In : Experimental Cell Research. 315, 12, p. 2105-2114 10 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2008

Histone H1.2 is translocated to mitochondria and associates with bak in bleomycin-induced apoptotic cells

Okamura, H., Yoshida, K., Amorim, B. R. & Haneji, T., Apr 1 2008, In : Journal of Cellular Biochemistry. 103, 5, p. 1488-1496 9 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)
2007

Calyculin A induces apoptosis and stimulates phosphorylation of p65NF-κB in human osteoblastic osteosarcoma MG63 cells

Tanaka, H., Yoshida, K., Okamura, H., Morimoto, H., Nagata, T. & Haneji, T., Aug 1 2007, In : International journal of oncology. 31, 2, p. 389-396 8 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Calyculin A stimulates the expression of TNF-α mRNA via phosphorylation of Akt in mouse osteoblastic MC3T3-E1 cells

Qiu, L., Yoshida, K., Amorim, B. R., Okamura, H. & Haneji, T., Jun 15 2007, In : Molecular and cellular endocrinology. 271, 1-2, p. 38-44 7 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Cobalt chloride induces apoptosis and zinc chloride suppresses cobalt-induced apoptosis by Bcl-2 expression in human submandibular gland HSG cells

Akita, K., Okamura, H., Yoshida, K., Morimoto, H., Ogawa-Iyehara, H. & Haneji, T., Oct 2007, In : International journal of oncology. 31, 4, p. 923-929 7 p.

Research output: Contribution to journalArticle

Open Access
10 Citations (Scopus)

Differential expression of protein phosphatase type 1 isotypes and nucleolin during cell cycle arrest

Morimoto, H., Ozaki, A., Okamura, H., Yoshida, K., Amorim, B. R., Tanaka, H., Kitamura, S. & Haneji, T., Jul 1 2007, In : Cell biochemistry and function. 25, 4, p. 369-375 7 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Expression of PTEN and Akt phosphorylation in lipopolysaccharide-treated NIH3T3 cells

Okamura, H., Yoshida, K., Sasaki, E., Qiu, L., Amorim, B. R., Morimoto, H. & Haneji, T., Feb 1 2007, In : Cell Biology International. 31, 2, p. 119-125 7 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

The transcriptional factor Osterix directly interacts with RNA helicase A

Amorim, B. R., Okamura, H., Yoshida, K., Qiu, L., Morimoto, H. & Haneji, T., Apr 6 2007, In : Biochemical and Biophysical Research Communications. 355, 2, p. 347-351 5 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2006

Okadaic acid induces phosphorylation of p65NF-κB on serine 536 and activates NF-κB transcriptional activity in human osteoblastic MG63 cells

Ozaki, A., Morimoto, H., Tanaka, H., Okamura, H., Yoshida, K., Amorim, B. R. & Haneji, T., Dec 1 2006, In : Journal of Cellular Biochemistry. 99, 5, p. 1275-1284 10 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2005

Double-stranded RNA-dependent protein kinase is required for bone calcification in MC3T3-E1 cells in vitro

Yoshida, K., Okamura, H., Amorim, B. R., Ozaki, A., Tanaka, H., Morimoto, H. & Haneji, T., Nov 15 2005, In : Experimental Cell Research. 311, 1, p. 117-125 9 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Okadaic acid induces tyrosine phosphorylation of IκBα that mediated by PKR pathway in human osteoblastic MG63 cells

Morimoto, H., Ozaki, A., Okamura, H., Yoshida, K., Kitamura, S. & Haneji, T., Aug 1 2005, In : Molecular and Cellular Biochemistry. 276, 1-2, p. 211-217 7 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

PTEN expression elicited by EGR-1 transcription factor in calyculin A-induced apoptotic cells

Okamura, H., Yoshida, K., Morimoto, H. & Haneji, T., Jan 1 2005, In : Journal of Cellular Biochemistry. 94, 1, p. 117-125 9 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)
2004

Double-stranded RNA mediates selective gene silencing of protein phosphatase type 1 delta isoform in HEK-293 cells

Morimoto, H., Okamura, H., Yoshida, K., Kitamura, S. & Haneji, T., Aug 2004, In : Journal of Enzyme Inhibition and Medicinal Chemistry. 19, 4, p. 327-331 5 p.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

Okadaic acid induces apoptosis through double-stranded RNA-dependent protein kinase/eukaryotic initiation factor-2α pathway in human osteoblastic MG63 cells

Morimoto, H., Okamura, H., Yoshida, K., Kitamura, S. & Haneji, T., Oct 1 2004, In : Journal of biochemistry. 136, 4, p. 433-438 6 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Okadaic acid stimulates expression of Fas receptor and Fas ligand by activation of nuclear factor kappa-B in human oral squamous carcinoma cells

Fujita, M., Goto, K., Yoshida, K., Okamura, H., Morimoto, H., Kito, S., Fukuda, J. & Haneji, T., Feb 2004, In : Oral Oncology. 40, 2, p. 199-206 8 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Transcription factor NF-Y regulates mdr1 expression through binding to inverted CCAAT sequence in drug-resistant human squamous carcinoma cells.

Okamura, H., Yoshida, K., Sasaki, E., Morimoto, H. & Haneji, T., Oct 2004, In : International journal of oncology. 25, 4, p. 1031-1037 7 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)
2003

Cleavage of nucleolin and argyrophilic nucleolar organizer region associated proteins in apoptosis-induced cells

Kito, S., Shimizu, K., Okamura, H., Yoshida, K., Morimoto, H., Fujita, M., Morimoto, Y., Ohba, T. & Haneji, T., Jan 24 2003, In : Biochemical and Biophysical Research Communications. 300, 4, p. 950-956 7 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Okadaic acid stimulates the expression of receptor activator of nuclear factor-kappa B ligand (RANKL) in mouse osteoblastic cells

Yoshida, K., Okamura, H., Morimoto, H., Nagata, T. & Haneji, T., Oct 1 2003, In : Biomedical Research. 14, 2, p. 126-132 7 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Transblot and cytochemical identification of avidin-interacting proteins in mitochondria of cultured cells

Sasaki, E., Okamoto, Y., Yoshida, K., Okamura, H., Shimizu, K., Nasu, F., Morimoto, H. & Haneji, T., Oct 1 2003, In : Histochemistry and Cell Biology. 120, 4, p. 327-333 7 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)