• 7811 Citations
  • 46 h-Index
1992 …2019
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Research Output 1992 2019

2019

Dickkopf3 (Dkk3) is required for maintaining the integrity of secretory vesicles in the mouse adrenal medulla

Habuta, M., Fujita, H., Sato, K., Bando, T., Inoue, J., Kondo, Y., Miyaishi, S., Kumon, H. & Ohuchi, H., Jan 1 2019, (Accepted/In press) In : Cell and Tissue Research.

Research output: Contribution to journalArticle

Adrenal Medulla
Secretory Vesicles
Adrenal Glands
Chromogranin A
Neuropeptide Y

Evolutionary history of teleost intron-containing and intron-less rhodopsin genes

Fujiyabu, C., Sato, K., Utari, N. M. L., Ohuchi, H., Shichida, Y. & Yamashita, T., Dec 1 2019, In : Scientific reports. 9, 1, 10653.

Research output: Contribution to journalArticle

Open Access
rhodopsin
introns
Lepisosteidae
genes
opsin
2 Citations (Scopus)

Glutathione accelerates osteoclast differentiation and inflammatory bone destruction

Fujita, H., Ochi, M., Ono, M., Aoyama, E., Ogino, T., Kondo, Y. & Ohuchi, H., Jan 1 2019, In : Free Radical Research.

Research output: Contribution to journalArticle

Osteoclasts
Glutathione
Bone
Bone and Bones
RANK Ligand
Open Access
Opsins
Myopia
Gene expression
Sclera
Tissue

Publisher Correction: Fgf10 is essential for limb and lung formation (Nature Genetics, (1999), 21, 1, (138-141), 10.1038/5096)

Sekine, K., Ohuchi, H., Fujiwara, M., Yamasaki, M., Yoshizawa, T., Sato, T., Yagishita, N., Matsui, D., Koga, Y., Itoh, N. & Kato, S., Jan 1 2019, In : Nature Genetics.

Research output: Contribution to journalComment/debate

Open Access
Extremities
Lung
2018
1 Citation (Scopus)

Bone morphogenetic protein signaling in distal patterning and intercalation during leg regeneration of the cricket, Gryllus bimaculatus

Ishimaru, Y., Bando, T., Ohuchi, H., Noji, S. & Mito, T., Aug 1 2018, In : Development Growth and Differentiation. 60, 6, p. 377-386 10 p.

Research output: Contribution to journalArticle

Gryllidae
Bone Morphogenetic Proteins
Regeneration
Leg
RNA Interference
2 Citations (Scopus)

Molecular mechanisms of limb regeneration: Insights from regenerating legs of the cricket gryllus bimaculatus

Bando, T., Mito, T., Hamada, Y., Ishimaru, Y., Noji, S. & Ohuchi, H., Jan 1 2018, In : International Journal of Developmental Biology. 62, 6-8, p. 559-569 11 p.

Research output: Contribution to journalArticle

Gryllidae
Regeneration
Leg
Extremities
Fats
1 Citation (Scopus)

Opn5L1 is a retinal receptor that behaves as a reverse and self-regenerating photoreceptor

Sato, K., Yamashita, T., Ohuchi, H., Takeuchi, A., Gotoh, H., Ono, K., Mizuno, M., Mizutani, Y., Tomonari, S., Sakai, K., Imamoto, Y., Wada, A. & Shichida, Y., Dec 1 2018, In : Nature Communications. 9, 1, 1255.

Research output: Contribution to journalArticle

Opsins
photoreceptors
vertebrates
Rhodopsin
Vertebrates
2 Citations (Scopus)

Pinopsin evolved as the ancestral dim-light visual opsin in vertebrates

Sato, K., Yamashita, T., Kojima, K., Sakai, K., Matsutani, Y., Yanagawa, M., Yamano, Y., Wada, A., Iwabe, N., Ohuchi, H. & Shichida, Y., Dec 1 2018, In : Communications Biology. 1, 1, 156.

Research output: Contribution to journalArticle

Open Access
Opsins
opsin
Rhodopsin
rhodopsin
Retinal Pigments
2017
1 Citation (Scopus)

Expression analysis of Dickkopf-related protein 3 (Dkk3) suggests its pleiotropic roles for a secretory glycoprotein in adult mouse

Inoue, J., Fujita, H., Bando, T., Kondo, Y., Kumon, H. & Ohuchi, H., Feb 1 2017, In : Journal of Molecular Histology. 48, 1, p. 29-39 11 p.

Research output: Contribution to journalArticle

Glycoproteins
Proteins
Gastrointestinal Tract
Thymus Gland
Gene Expression
1 Citation (Scopus)

Eye development and photoreception of a hemimetabolous insect, gryllus bimaculatus

Ohuchi, H., Bando, T., Mito, T. & Noji, S., Jan 1 2017, The Cricket as a Model Organism: Development, Regeneration, and Behavior. Springer Japan, p. 49-62 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Opsins
Gryllus bimaculatus
Insects
Genes
eyes

Preface

Wilson Horch, H., Mito, T., Popadić, A., Ohuchi, H. & Noji, S., Jan 1 2017, The Cricket as a Model Organism: Development, Regeneration, and Behavior. Springer Japan, p. v-vi

Research output: Chapter in Book/Report/Conference proceedingForeword/postscript

10 Citations (Scopus)

Relationship between somatic mosaicism of Pax6 mutation and variable developmental eye abnormalities-an analysis of CRISPR genome-edited mouse embryos

Yasue, A., Kono, H., Habuta, M., Bando, T., Sato, K., Inoue, J., Oyadomari, S., Noji, S., Tanaka, E. & Ohuchi, H., Jan 1 2017, In : Scientific Reports. 7, 1, 53.

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
Eye Abnormalities
Mosaicism
Embryonic Structures
Genome
7 Citations (Scopus)

The cricket as a model organism: Development, regeneration, and behavior

Wilson Horch, H., Mito, T., Popadić, A., Ohuchi, H. & Noji, S., Jan 1 2017, Springer Japan. 376 p.

Research output: Book/ReportBook

Gryllidae
Regeneration
organisms
Pest control
Physiology
2016
1 Citation (Scopus)
Microphthalmos
Optic Nerve
Retina
Autopsy
Optics
6 Citations (Scopus)

Phytoestrogen suppresses efflux of the diagnostic marker protoporphyrin IX in lung carcinoma

Fujita, H., Nagakawa, K., Kobuchi, H., Ogino, T., Kondo, Y., Inoue, K., Shuin, T., Utsumi, T., Utsumi, K., Sasaki, J. & Ohuchi, H., Apr 1 2016, In : Cancer Research. 76, 7, p. 1837-1846 10 p.

Research output: Contribution to journalArticle

Phytoestrogens
Photosensitizing Agents
Genistein
Carcinoma
Lung
17 Citations (Scopus)

TGF-β signaling in insects regulates metamorphosis via juvenile hormone biosynthesis

Ishimaru, Y., Tomonari, S., Matsuoka, Y., Watanabe, T., Miyawaki, K., Bando, T., Tomioka, K., Ohuchi, H., Noji, S. & Mito, T., May 17 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 20, p. 5634-5639 6 p.

Research output: Contribution to journalArticle

Juvenile Hormones
Insects
Gryllidae
Vertebrates
Corpora Allata
7 Citations (Scopus)

Two Opsin 3-Related Proteins in the Chicken Retina and Brain: A TMT-Type Opsin 3 Is a Blue-Light Sensor in Retinal Horizontal Cells, Hypothalamus, and Cerebellum

Kato, M., Sugiyama, T., Sakai, K., Yamashita, T., Fujita, H., Sato, K., Tomonari, S., Shichida, Y. & Ohuchi, H., Nov 1 2016, In : PLoS One. 11, 11, e0163925.

Research output: Contribution to journalArticle

Retinal Horizontal Cells
Opsins
opsin
cerebellum
hypothalamus
11 Citations (Scopus)

Two UV-sensitive photoreceptor proteins, Opn5m and Opn5m2 in ray-finned fish with distinct molecular properties and broad distribution in the retina and brain

Sato, K., Yamashita, T., Haruki, Y., Ohuchi, H., Kinoshita, M. & Shichida, Y., May 1 2016, In : PLoS One. 11, 5, e0155339.

Research output: Contribution to journalArticle

Skates (Fish)
Actinopterygii
photoreceptors
retina
Fish
2015
8 Citations (Scopus)

Involvement of dachshund and distal-less in distal pattern formation of the cricket leg during regeneration

Ishimaru, Y., Nakamura, T., Bando, T., Matsuoka, Y., Ohuchi, H., Noji, S. & Mito, T., 2015, In : Scientific Reports. 5, p. 8387 1 p.

Research output: Contribution to journalArticle

Gryllidae
Tibia
Regeneration
Leg
RNA Interference
16 Citations (Scopus)

Leg regeneration is epigenetically regulated by histone H3K27 methylation in the cricket Gryllus bimaculatus

Hamada, Y., Bando, T., Nakamura, T., Ishimaru, Y., Mito, T., Noji, S., Tomioka, K. & Ohuchi, H., Sep 1 2015, In : Development. 142, 17, p. 2916-2927 12 p.

Research output: Contribution to journalArticle

Gryllidae
Histones
Methylation
Regeneration
Leg
2014
5 Citations (Scopus)

An extended steepness model for leg-size determination based on Dachsous/Fat trans-dimer system

Yoshida, H., Bando, T., Mito, T., Ohuchi, H. & Noji, S., Mar 11 2014, In : Scientific Reports. 4, 4335.

Research output: Contribution to journalArticle

Gryllidae
Leg
Fats
Regeneration
Organ Size
20 Citations (Scopus)

Evolution of mammalian Opn5 as a specialized UV-absorbing pigment by a single amino acid mutation

Yamashita, T., Ono, K., Ohuchi, H., Yumoto, A., Gotoh, H., Tomonari, S., Sakai, K., Fujita, H., Imamoto, Y., Noji, S., Nakamura, K. & Shichida, Y., Feb 14 2014, In : Journal of Biological Chemistry. 289, 7, p. 3991-4000 10 p.

Research output: Contribution to journalArticle

Pigments
Brain
Amino Acids
Mutation
Mammals
2013
24 Citations (Scopus)

Analysis of RNA-seq data reveals involvement of JAK/STAT signalling during leg regeneration in the cricket Gryllus bimaculatus

Bando, T., Ishimaru, Y., Kida, T., Hamada, Y., Matsuoka, Y., Nakamura, T., Ohuchi, H., Noji, S. & Mito, T., 2013, In : Development. 140, 5, p. 959-964 6 p.

Research output: Contribution to journalArticle

Gryllidae
Regeneration
Leg
RNA
RNA Interference
12 Citations (Scopus)

Improvement of the efcacy of 5-aminolevulinic acid-mediated photodynamic treatment in human oral squamous cell carcinoma hsc-4

Yamamotoarf, M., Fujitaa, H., Katase, N., Inouec, K., Nagatsuka, H., Utsumi, K., Sasaki, J. & Ohuchi, H., 2013, In : Acta Medica Okayama. 67, 3, p. 153-164 12 p.

Research output: Contribution to journalArticle

Aminolevulinic Acid
ATP-Binding Cassette Transporters
Squamous Cell Carcinoma
Ferrochelatase
Mouth Neoplasms
1 Citation (Scopus)
Regenerative Medicine
Cells
Opsins
Aberrations
Gene expression
6 Citations (Scopus)

The expression of LIM-homeobox genes, Lhx1 and Lhx5, in the forebrain is essential for neural retina differentiation

Inoue, J., Ueda, Y., Bando, T., Mito, T., Noji, S. & Ohuchi, H., Sep 2013, In : Development Growth and Differentiation. 55, 7, p. 668-675 8 p.

Research output: Contribution to journalArticle

Homeobox Genes
Prosencephalon
Retina
Retinal Pigment Epithelium
Electroporation
2012
24 Citations (Scopus)

A non-mammalian type opsin 5 functions dually in the photoreceptive and non-photoreceptive organs of birds

Ohuchi, H., Yamashita, T., Tomonari, S., Fujita-Yanagibayashi, S., Sakai, K., Noji, S. & Shichida, Y., Feb 14 2012, In : PLoS One. 7, 2, e31534.

Research output: Contribution to journalArticle

Opsins
opsin
Birds
Chickens
birds
13 Citations (Scopus)

Establishment of a novel system to elucidate the mechanisms underlying light-induced ripening of strawberry fruit with an Agrobacterium-mediated RNAi technique

Miyawaki, K., Fukuoka, S., Kadomura, Y., Hamaoka, H., Mito, T., Ohuchi, H., Schwab, W. & Noji, S., 2012, In : Plant Biotechnology. 29, 3, p. 271-277 7 p.

Research output: Contribution to journalArticle

Fragaria
Agrobacterium
RNA Interference
strawberries
Fruit
11 Citations (Scopus)

Functional analysis of the role of eyes absent and sine oculis in the developing eye of the cricket Gryllus bimaculatus

Takagi, A., Kurita, K., Terasawa, T., Nakamura, T., Bando, T., Moriyama, Y., Mito, T., Noji, S. & Ohuchi, H., Feb 2012, In : Development Growth and Differentiation. 54, 2, p. 227-240 14 p.

Research output: Contribution to journalArticle

Gryllidae
RNA Interference
tetrahydrozoline
Stem Cells
Cornea
7 Citations (Scopus)

Lhx1 in the proximal region of the optic vesicle permits neural retina development in the chicken

Kawaue, T., Okamoto, M., Matsuyo, A., Inoue, J., Ueda, Y., Tomonari, S., Noji, S. & Ohuchi, H., Nov 15 2012, In : Biology Open. 1, 11, p. 1083-1093 11 p.

Research output: Contribution to journalArticle

optics
retina
Retina
Chickens
Optics
93 Citations (Scopus)

Non-transgenic genome modifications in a hemimetabolous insect using zinc-finger and TAL effector nucleases

Watanabe, T., Ochiai, H., Sakuma, T., Horch, H. W., Hamaguchi, N., Nakamura, T., Bando, T., Ohuchi, H., Yamamoto, T., Noji, S. & Mito, T., 2012, In : Nature Communications. 3, 1017.

Research output: Contribution to journalArticle

nuclease
effectors
insects
genome
Zinc Fingers
12 Citations (Scopus)

Wakayama symposium: Epithelial-mesenchymal interactions in eyelid development

Ohuchi, H., 2012, In : Ocular Surface. 10, 4, p. 212-216 5 p.

Research output: Contribution to journalReview article

Eyelids
Receptor, Fibroblast Growth Factor, Type 2
MAP Kinase Kinase Kinases
Epithelium
Parturition
2011
39 Citations (Scopus)

Ancestral functions of Delta/Notch signaling in the formation of body and leg segments in the cricket Gryllus bimaculatus

Mito, T., Shinmyo, Y., Kurita, K., Nakamura, T., Ohuchi, H. & Noji, S., Sep 1 2011, In : Development. 138, 17, p. 3823-3833 11 p.

Research output: Contribution to journalArticle

Gryllidae
Leg
Arthropods
RNA Interference
Spiders
14 Citations (Scopus)

Atelocollagen-mediated systemic administration of myostatin-targeting siRNA improves muscular atrophy in caveolin-3-deficient mice

Kawakami, E., Kinouchi, N., Adachi, T., Ohsawa, Y., Ishimaru, N., Ohuchi, H., Sunada, Y., Hayashi, Y., Tanaka, E. & Noji, S., Jan 2011, In : Development Growth and Differentiation. 53, 1, p. 48-54 7 p.

Research output: Contribution to journalArticle

Caveolin 3
Myostatin
Muscular Atrophy
Small Interfering RNA
Limb-Girdle Muscular Dystrophies
21 Citations (Scopus)

Autotaxin is required for the cranial neural tube closure and establishment of the midbrain-hindbrain boundary during mouse development

Koike, S., Yutoh, Y., Keino-Masu, K., Noji, S., Masu, M. & Ohuchi, H., Feb 2011, In : Developmental Dynamics. 240, 2, p. 413-421 9 p.

Research output: Contribution to journalArticle

Rhombencephalon
Neural Tube
Mesencephalon
Embryonic Structures
Neurulation
22 Citations (Scopus)

Cricket body size is altered by systemic RNAi against insulin signaling components and epidermal growth factor receptor

Dabour, N., Bando, T., Nakamura, T., Miyawaki, K., Mito, T., Ohuchi, H. & Noji, S., Sep 2011, In : Development Growth and Differentiation. 53, 7, p. 857-869 13 p.

Research output: Contribution to journalArticle

Gryllidae
Body Size
RNA Interference
Epidermal Growth Factor Receptor
Sirolimus
2 Citations (Scopus)

Expression of myelin genes in the developing chick retina

Gotoh, H., Ueda, T., Uno, A., Ohuchi, H., Ikenaka, K. & Ono, K., Dec 2011, In : Gene Expression Patterns. 11, 8, p. 471-475 5 p.

Research output: Contribution to journalArticle

Myelin Sheath
Retina
Gene Expression
Oligodendroglia
Myelin Proteolipid Protein
11 Citations (Scopus)

Lowfat, a mammalian Lix1 homologue, regulates leg size and growth under the Dachsous/Fat signaling pathway during tissue regeneration†

Bando, T., Hamada, Y., Kurita, K., Nakamura, T., Mito, T., Ohuchi, H. & Noji, S., Jun 2011, In : Developmental Dynamics. 240, 6, p. 1440-1453 14 p.

Research output: Contribution to journalArticle

Regeneration
Leg
Fats
Growth
Nymph
15 Citations (Scopus)

Regulation of leg size and shape: Involvement of the Dachsous-fat signaling pathway

Bando, T., Mito, T., Nakamura, T., Ohuchi, H. & Noji, S., May 2011, In : Developmental Dynamics. 240, 5, p. 1028-1041 14 p.

Research output: Contribution to journalArticle

Leg
Fats
Warts
Regeneration
Neurofibromin 2
32 Citations (Scopus)

The advent of RNA interference in Entomology

Mito, T., Nakamura, T., Bando, T., Ohuchi, H. & Noji, S., Jan 2011, In : Entomological Science. 14, 1, p. 1-8 8 p.

Research output: Contribution to journalArticle

entomology
RNA interference
RNA
insect
insects
22 Citations (Scopus)

Vertebrate ancient-long opsin has molecular properties intermediate between those of vertebrate and invertebrate visual pigments

Sato, K., Yamashita, T., Ohuchi, H. & Shichida, Y., Dec 6 2011, In : Biochemistry. 50, 48, p. 10484-10490 7 p.

Research output: Contribution to journalArticle

Opsins
Retinal Pigments
Invertebrates
Vertebrates
Pigments
2010
4 Citations (Scopus)

Autotaxin controls caudal diencephalon-mesencephalon development in the chick

Ohuchi, H., Fukui, H., Matsuyo, A., Tomonari, S., Tanaka, M., Arai, H., Noji, S. & Aoki, J., Oct 2010, In : Developmental Dynamics. 239, 10, p. 2647-2658 12 p.

Research output: Contribution to journalArticle

Diencephalon
Mesencephalon
RNA Interference
Neuroepithelial Cells
Lysophospholipids
7 Citations (Scopus)

Delivery of small interfering RNA with a synthetic collagen poly(Pro-Hyp-Gly) for gene silencing in vitro and in vivo

Adachi, T., Kawakami, E., Ishimaru, N., Ochiya, T., Hayashi, Y., Ohuchi, H., Tanihara, M., Tanaka, E. & Noji, S., Oct 2010, In : Development Growth and Differentiation. 52, 8, p. 693-699 7 p.

Research output: Contribution to journalArticle

Gene Silencing
Small Interfering RNA
Collagen
Luciferases
Skeletal Muscle
48 Citations (Scopus)

Imaging of transgenic cricket embryos reveals cell movements consistent with a syncytial patterning mechanism

Nakamura, T., Yoshizaki, M., Ogawa, S., Okamoto, H., Shinmyo, Y., Bando, T., Ohuchi, H., Noji, S. & Mito, T., 2010, In : Current Biology. 20, 18, p. 1641-1647 7 p.

Research output: Contribution to journalArticle

Gryllidae
cell movement
Blastoderm
Cell Movement
Insects
88 Citations (Scopus)

Opn5 is a UV-sensitive bistable pigment that couples with Gi subtype of G protein

Yamashita, T., Ohuchi, H., Tomonari, S., Ikeda, K., Sakai, K. & Shichida, Y., Dec 21 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 51, p. 22084-22089 6 p.

Research output: Contribution to journalArticle

GTP-Binding Proteins
Opsins
Chickens
Ultraviolet Rays
Light
2009
55 Citations (Scopus)

Regulation of leg size and shape by the Dachsous/Fat signalling pathway during regeneration

Bando, T., Mito, T., Maeda, Y., Nakamura, T., Ito, F., Watanabe, T., Ohuchi, H. & Noji, S., Jul 1 2009, In : Development. 136, 13, p. 2235-2245 11 p.

Research output: Contribution to journalArticle

Regeneration
Leg
Fats
Gryllidae
RNA Interference
8 Citations (Scopus)

Subtype-specific expression of Fgf19 during horizontal cell development of the chicken retina

Okamoto, M., Bito, T., Noji, S. & Ohuchi, H., Jun 2009, In : Gene Expression Patterns. 9, 5, p. 306-313 8 p.

Research output: Contribution to journalArticle

Fibroblast Growth Factors
Retina
Chickens
Axons
Homeobox Genes
2008
55 Citations (Scopus)

Atelocollagen-mediated local and systemic applications of myostatin-targeting siRNA increase skeletal muscle mass

Kinouchi, N., Ohsawa, Y., Ishimaru, N., Ohuchi, H., Sunada, Y., Hayashi, Y., Tanimoto, Y., Moriyama, K. & Noji, S., Aug 2008, In : Gene Therapy. 15, 15, p. 1126-1130 5 p.

Research output: Contribution to journalArticle

Myostatin
Small Interfering RNA
Skeletal Muscle
Muscular Atrophy
Therapeutic Uses
21 Citations (Scopus)

Divergent and conserved roles of extradenticle in body segmentation and appendage formation, respectively, in the cricket Gryllus bimaculatus

Mito, T., Ronco, M., Uda, T., Nakamura, T., Ohuchi, H. & Noji, S., Jan 1 2008, In : Developmental Biology. 313, 1, p. 67-79 13 p.

Research output: Contribution to journalArticle

Gryllidae
Drosophila
RNA Interference
Head
Insects