• 237 Citations
  • 8 h-Index
20092019
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Research Output 2009 2019

  • 237 Citations
  • 8 h-Index
  • 15 Article
  • 3 Review article
2019
Acrolein
Cycloaddition
Dipeptides
Salts
Diamines

Thioureas as Highly Active Catalysts for Biomimetic Bromocyclization of Geranyl Derivatives

Terazaki, M., Shiomoto, K. I., Mizoguchi, H. & Sakakura, A., Jan 1 2019, In : Organic Letters.

Research output: Contribution to journalArticle

Thiourea
Biomimetics
thioureas
biomimetics
reactivity

Zn(OTf)2-mediated annulations of: N -propargylated tetrahydrocarbolines: Divergent synthesis of four distinct alkaloidal scaffolds

Yorimoto, S., Tsubouchi, A., Mizoguchi, H., Oikawa, H., Tsunekawa, Y., Ichino, T., Maeda, S. & Oguri, H., Jan 1 2019, In : Chemical Science. 10, 22, p. 5686-5698 13 p.

Research output: Contribution to journalArticle

Open Access
Scaffolds
Alkenylation
Kinetics
Acids
Substrates
2018
1 Citation (Scopus)

Design and de Novo Synthesis of 6-Aza-artemisinins

Bonepally, K. R., Hiruma, T., Mizoguchi, H., Ochiai, K., Suzuki, S., Oikawa, H., Ishiyama, A., Hokari, R., Iwatsuki, M., Otoguro, K., Omura, S. & Oguri, H., Aug 3 2018, In : Organic Letters. 20, 15, p. 4667-4671 5 p.

Research output: Contribution to journalArticle

Artemisinins
cyclohexane
assembly
Antimalarials
synthesis
2017
1 Citation (Scopus)
Cardenolides
Steroids
Bioactivity
Functional groups
4 Citations (Scopus)

Stereo-controlled synthesis of functionalized tetrahydropyridines based on the cyanomethylation of 1,6-dihydropyridines and generation of anti-hepatitis C virus agents

Watanabe, R., Mizoguchi, H., Oikawa, H., Ohashi, H., Watashi, K. & Oguri, H., Jan 1 2017, In : Bioorganic and Medicinal Chemistry. 25, 11, p. 2851-2855 5 p.

Research output: Contribution to journalArticle

Dihydropyridines
Viruses
Hepacivirus
Bearings (structural)
Heterocyclic Compounds
3 Citations (Scopus)

The Development of Alkoxide-Directed Metallacycle-Mediated Annulative Cross-Coupling Chemistry

Micalizio, G. C. & Mizoguchi, H., Apr 1 2017, In : Israel Journal of Chemistry. 57, 3, p. 228-238 11 p.

Research output: Contribution to journalReview article

Organometallics
Biological Products
Organic Chemistry
2016
2 Citations (Scopus)

Acceleration of metallacycle-mediated alkyne–alkyne cross-coupling with TMSCl

Cassidy, J. S., Mizoguchi, H. & Micalizio, G. C., Jan 1 2016, In : Tetrahedron Letters. 57, 34, p. 3848-3850 3 p.

Research output: Contribution to journalArticle

Alkynes
Hexanes
Organometallics
Titanium
n-butyllithium
1 Citation (Scopus)
Indole Alkaloids
Cyclization
Biological Products
Scaffolds
Secologanin Tryptamine Alkaloids
8 Citations (Scopus)

Synthesis of Angularly Substituted trans-Fused Decalins through a Metallacycle-Mediated Annulative Cross-Coupling Cascade

Mizoguchi, H. & Micalizio, G. C., Jan 1 2016, In : Angewandte Chemie - International Edition. 55, 42, p. 13099-13103 5 p.

Research output: Contribution to journalArticle

Stereochemistry
Cycloaddition
Protonation
Isomerization
Titanium
2015
8 Citations (Scopus)

LiOOt-Bu as a terminal oxidant in a titanium alkoxide-mediated [2+2+2] reaction cascade

Kim, W. S., Aquino, C., Mizoguchi, H. & Micalizio, G. C., May 25 2015, In : Tetrahedron Letters. 56, 23, p. 3557-3559 3 p., 45698.

Research output: Contribution to journalArticle

Titanium
Oxidants
Oxidation
Organometallics
allyl alcohol
17 Citations (Scopus)

Synthesis of Highly Functionalized Decalins via Metallacycle-Mediated Cross-Coupling

Mizoguchi, H. & Micalizio, G. C., May 27 2015, In : Journal of the American Chemical Society. 137, 20, p. 6624-6628 5 p.

Research output: Contribution to journalArticle

Organometallics
Titanium
Extrusion
Cycloaddition
Protonation
18 Citations (Scopus)

Synthesis of multiply substituted 1,6-dihydropyridines through Cu(I)-catalyzed 6-endo cyclization

Mizoguchi, H., Watanabe, R., Minami, S., Oikawa, H. & Oguri, H., Jun 7 2015, In : Organic and Biomolecular Chemistry. 13, 21, p. 5955-5963 9 p.

Research output: Contribution to journalArticle

Dihydropyridines
Cyclization
assembly
copper
oxidation
2014
107 Citations (Scopus)

Biogenetically inspired synthesis and skeletal diversification of indole alkaloids

Mizoguchi, H., Oikawa, H. & Oguri, H., Jan 1 2014, In : Nature Chemistry. 6, 1, p. 57-64 8 p.

Research output: Contribution to journalArticle

Indole Alkaloids
Alkaloids
Scaffolds
Cyclization
Secologanin Tryptamine Alkaloids
20 Citations (Scopus)

Synthesis of angularly substituted trans-fused hydroindanes by convergent coupling of acyclic precursors

Jeso, V., Aquino, C., Cheng, X., Mizoguchi, H., Nakashige, M. & Micalizio, G. C., Jun 11 2014, In : Journal of the American Chemical Society. 136, 23, p. 8209-8212 4 p.

Research output: Contribution to journalArticle

Bearings (structural)
Alkynes
Cycloaddition
Protonation
Organometallics
2012
8 Citations (Scopus)

Hg(OTf)2-catalyzed direct vinylation of tryptamines and versatile applications for tandem reactions

Mizoguchi, H., Oikawa, H. & Oguri, H., Jun 7 2012, In : Organic and Biomolecular Chemistry. 10, 21, p. 4236-4242 7 p.

Research output: Contribution to journalArticle

tryptamines
Tryptamines
Gems
Indoles
Alkynes
8 Citations (Scopus)

Parallel and four-step synthesis of natural-product-inspired scaffolds through modular assembly and divergent cyclization

Oguri, H., Mizoguchi, H., Oikawa, H., Ishiyama, A., Iwatsuki, M., Otoguro, K. & Ömura, S., Jun 22 2012, In : Beilstein Journal of Organic Chemistry. 8, p. 930-940 11 p.

Research output: Contribution to journalArticle

Cyclization
Biological Products
Scaffolds
Bearings (structural)
Rhodium
2009
31 Citations (Scopus)

Divergent and expeditious access to fused skeletons inspired by indole alkaloids and transtaganolides

Mizoguchi, H., Oguri, H., Tsuge, K. & Oikawa, H., Jul 16 2009, In : Organic Letters. 11, 14, p. 3016-3019 4 p.

Research output: Contribution to journalArticle

Indole Alkaloids
Rhodium
alkaloids
Cyclization
indoles