• 1101 Citations
  • 19 h-Index
1979 …2017
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Research Output 1979 2017

  • 1101 Citations
  • 19 h-Index
  • 83 Article
  • 1 Comment/debate
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Article
2016
9 Citations (Scopus)

Muscarinic acetylcholine receptor M1 and M3 subtypes mediate acetylcholine-induced endothelium-independent vasodilatation in rat mesenteric arteries

Tangsucharit, P., Takatori, S., Zamami, Y., Goda, M., Pakdeechote, P., Kawasaki, H. & Takayama, F., Jan 1 2016, In : Journal of Pharmacological Sciences. 130, 1, p. 24-32 9 p.

Research output: Contribution to journalArticle

Muscarinic M3 Receptors
Muscarinic M1 Receptors
Mesenteric Arteries
Muscarinic Receptors
Vasodilation
2015
2 Citations (Scopus)

Nicotine facilitates reinnervation of phenol-injured perivascular adrenergic nerves in the rat mesenteric resistance artery

Takatori, S., Fujiwara, H., Hagimori, K., Hashikawa-Hobara, N., Yokomizo, A., Takayama, F., Tangsucharit, P., Ono, N. & Kawasaki, H., Feb 5 2015, In : European Journal of Pharmacology. 748, p. 1-9 9 p.

Research output: Contribution to journalArticle

Mesenteric Arteries
Phenol
Nicotine
Adrenergic Agents
Tyrosine 3-Monooxygenase
2014
8 Citations (Scopus)

Oral administration of eicosapentaenoic acid or docosahexaenoic acid modifies cardiac function and ameliorates congestive heart failure in male Rats

Yamanushi, T. T., Kabuto, H., Hirakawa, E., Janjua, N., Takayama, F. & Mankura, M., 2014, In : Journal of Nutrition. 144, 4, p. 467-474 8 p.

Research output: Contribution to journalArticle

Eicosapentaenoic Acid
Docosahexaenoic Acids
Oral Administration
Heart Failure
Control Groups
2013
14 Citations (Scopus)

Effects of squalene/squalane on dopamine levels, antioxidant enzyme activity, and fatty acid composition in the striatum of Parkinson's disease mouse model

Kabuto, H., Yamanushi, T. T., Janjua, N., Takayama, F. & Mankura, M., 2013, In : Journal of Oleo Science. 62, 1, p. 21-28 8 p.

Research output: Contribution to journalArticle

Squalene
Enzyme activity
Antioxidants
Fatty acids
Dopamine
2012
39 Citations (Scopus)

Anti-oxidative and anti-inflammatory effects of spirulina on rat model of non-alcoholic steatohepatitis

Pak, W., Takayama, F., Mine, M., Nakamoto, K., Kodo, Y., Mankura, M., Egashira, T., Kawasaki, H. & Mori, A., Nov 2012, In : Journal of Clinical Biochemistry and Nutrition. 51, 3, p. 227-234 8 p.

Research output: Contribution to journalArticle

Spirulina
Fatty Liver
Phycocyanin
Rats
Anti-Inflammatory Agents
9 Citations (Scopus)

Do cholinergic nerves innervating rat mesenteric arteries regulate vascular tone?

Tangsucharit, P., Takatori, S., Sun, P., Zamami, Y., Goda, M., Pakdeechote, P., Takayama, F. & Kawasaki, H., 2012, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 303, 11

Research output: Contribution to journalArticle

Mesenteric Arteries
Cholinergic Agents
Blood Vessels
Neostigmine
Capsaicin
3 Citations (Scopus)
2011

Functional food development to target NASH: Spirulina intervening in both hits

Takayama, F., Nakamoto, K., Mine, M., Sugimoto, S., Pak, W., Egashira, T., Kawasaki, H., Kodo, Y., Mankura, M., Okada, S. & Mori, A., Oct 31 2011, In : Japanese Journal of Clinical Chemistry. 40, 4, p. 333-340 8 p.

Research output: Contribution to journalArticle

Spirulina
Functional Food
Oxidative stress
Liver
Oxidative Stress
15 Citations (Scopus)

Structure-based design, synthesis, and nonalcoholic steatohepatitis (NASH)-preventive effect of phenylpropanoic acid peroxisome proliferator- activated receptor (PPAR) α-selective agonists

Ban, S., Kasuga, J. I., Nakagome, I., Nobusada, H., Takayama, F., Hirono, S., Kawasaki, H., Hashimoto, Y. & Miyachi, H., May 15 2011, In : Bioorganic and Medicinal Chemistry. 19, 10, p. 3183-3191 9 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Acids
Lead compounds
Molecular modeling
Structure-Activity Relationship
2010

DHA製品の開発と機能性評価

Takayama, F., 2010, In : ジャパンフードサイエンス. 49, 1, p. 45-52 8 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Effects of docosahexaenoic acid in an experimental rat model of nonalcoholic steatohepatitis

Takayama, F., Nakamoto, K., Totani, N., Yamanushi, T., Kabuto, H., Kaneyuki, T. & Mankura, M., 2010, In : Journal of Oleo Science. 59, 8, p. 407-414 8 p.

Research output: Contribution to journalArticle

Docosahexaenoic Acids
Rats
Liver
Nutrition
Acids
2009
22 Citations (Scopus)

A novel animal model of nonalcoholic steatohepatitis (NASH): Hypoxemia enhances the development of NASH

Takayama, F., Egashira, T., Kawasaki, H., Mankura, M., Nakamoto, K., Okada, S. & Mori, A., Nov 2009, In : Journal of Clinical Biochemistry and Nutrition. 45, 3, p. 335-340 6 p.

Research output: Contribution to journalArticle

Nutrition
Choline
High Fat Diet
Animals
Animal Models
37 Citations (Scopus)

Beneficial effects of fermented green tea extract in a rat model of non-alcoholic steatohepatitis

Nakamoto, K., Takayama, F., Mankura, M., Hidaka, Y., Egashira, T., Ogino, T., Kawasaki, H. & Mori, A., May 2009, In : Journal of Clinical Biochemistry and Nutrition. 44, 3, p. 239-246 8 p.

Research output: Contribution to journalArticle

Tea
Fatty Liver
Rats
Liver
Oxidative stress
15 Citations (Scopus)

Beneficial effects of Vitis coignetiae Pulliat leaves on nonalcoholic steatohepatitis in a rat model

Takayama, F., Nakamoto, K., Kawasaki, H., Mankura, M., Egashira, T., Ueki, K., Hasegawa, A., Okada, S. & Mori, A., May 2009, In : Acta Medica Okayama. 63, 2, p. 105-111 7 p.

Research output: Contribution to journalArticle

Vitis
Liver
Rats
Oxidative stress
Animals
2008

Effect of postprandial hyperglycemia and hyperinsulinemia on vascular responsiveness

Zamami, Y., Takatori, S., Iwatani, Y., Yamawaki, K., Miyashita, S., Yabumae, N., Takayama, F., Mio, M. & Kawasaki, H., Mar 2008, In : Yakugaku Zasshi. 128, 3, p. 419-424 6 p.

Research output: Contribution to journalArticle

Hyperinsulinism
Hyperglycemia
Blood Vessels
Insulin
Spinal Cord Stimulation
2007
1 Citation (Scopus)

Mechanisms underlying enhanced vasodilator responses to various vasodilator agents following endothelium removal in rat mesenteric resistance arteries

Iwatani, Y., Numa, H., Atagi, S., Takayama, F., Mio, M. & Kawasaki, H., Apr 2007, In : Yakugaku Zasshi. 127, 4, p. 729-733 5 p.

Research output: Contribution to journalArticle

Mesenteric Arteries
Vasodilator Agents
Endothelium
Vasodilation
Perfusion
2006
25 Citations (Scopus)

Histamine-induced vasodilation and vasoconstriction in the mesenteric resistance artery of the rat

Jin, H., Koyama, T., Hatanaka, Y., Akiyama, S., Takayama, F. & Kawasaki, H., Jan 4 2006, In : European Journal of Pharmacology. 529, 1-3, p. 136-144 9 p.

Research output: Contribution to journalArticle

Mesenteric Arteries
Vasoconstriction
Vasodilation
Histamine
Endothelium
25 Citations (Scopus)
Calcitonin Gene-Related Peptide
Neuropeptide Y
Phenol
Nerve Growth Factor
Blood Vessels
55 Citations (Scopus)

Neuronal nitric-oxide synthase inhibition facilitates adrenergic neurotransmission in rat mesenteric resistance arteries

Hatanaka, Y., Hobara, N., Honghua, J., Akiyama, S., Nawa, H., Kobayashi, Y., Takayama, F., Gomita, Y. & Kawasaki, H., Feb 2006, In : Journal of Pharmacology and Experimental Therapeutics. 316, 2, p. 490-497 8 p.

Research output: Contribution to journalArticle

Nitric Oxide Synthase Type I
Mesenteric Arteries
NG-Nitroarginine Methyl Ester
Synaptic Transmission
Adrenergic Agents
2005
5 Citations (Scopus)

Effect of adrenomedullin on adrenergic vasoconstriction in mesenteric resistance arteries of the rat

Akiyama, S., Hatanaka, Y., Hobara, N., Honghua, J., Kosugi, K., Takayama, F. & Kawasaki, H., 2005, In : Journal of Pharmacological Sciences. 99, 3, p. 264-271 8 p.

Research output: Contribution to journalArticle

Adrenomedullin
Mesenteric Arteries
Vasoconstriction
Adrenergic Agents
Calcitonin Gene-Related Peptide
27 Citations (Scopus)

Long-term inhibition of angiotensin prevents reduction of periarterial innervation of calcitonin gene-related peptide (CGRP)-containing nerves in spontaneously hypertensive rats

Hobara, N., Gessei-Tsutsumi, N., Goda, M., Takayama, F., Akiyama, S., Kurosaki, Y. & Kawasaki, H., May 2005, In : Hypertension Research. 28, 5, p. 465-474 10 p.

Research output: Contribution to journalArticle

Calcitonin Gene-Related Peptide
Angiotensins
Inbred SHR Rats
Nerve Fibers
Mesenteric Arteries
2003
9 Citations (Scopus)

Calcium disodium edetate enhances type A monoamine oxidase activity in monkey brain

Egashira, T., Sakai, K., Sakurai, M. & Takayama, F., Sep 2003, In : Biological Trace Element Research. 94, 3, p. 203-211 9 p.

Research output: Contribution to journalArticle

Monoamine Oxidase
Edetic Acid
Haplorhini
Brain
Mitochondria
7 Citations (Scopus)
Kampo Medicine
Aptitude
Oral Administration
Tocopherols
Ascorbic Acid
6 Citations (Scopus)

Effects of zinc ion on type A monoamine oxidase in monkey brain mitochondria

Egashira, T., Takayama, F. & Sakai, K., Feb 15 2003, In : Biochemical Pharmacology. 65, 4, p. 625-627 3 p.

Research output: Contribution to journalArticle

Mitochondria
Monoamine Oxidase
Haplorhini
Zinc
Brain
3 Citations (Scopus)

Inhibition by Zn2+ of A-form monoamine oxidase in monkey brain mitochondria

Egashira, T., Takayama, F. & Sakai, K., Mar 1 2003, In : Journal of Pharmacological Sciences. 91, 3, p. 239-245 7 p.

Research output: Contribution to journalArticle

Monoamine Oxidase
Haplorhini
Mitochondria
Brain
Serotonin
2 Citations (Scopus)
Glycyrrhetinic Acid
Glycyrrhizic Acid
Pharmacokinetics
8 Citations (Scopus)

Zinc benzoate, a contaminating environmental compound derived from polystyrene resin inhibits A-type monoamine oxidase

Egashira, T., Sakai, K., Takayama, F., Sakurai, M. & Yoshida, S., Nov 30 2003, In : Toxicology Letters. 145, 2, p. 161-165 5 p.

Research output: Contribution to journalArticle

Benzoates
Polystyrenes
Monoamine Oxidase
Zinc
Resins
2002
19 Citations (Scopus)

Change in free radical-related substances in plasma following ischemia-reperfusion in rat liver

Iwamoto, A., Egashira, T., Takayama, F., Yamanaka, Y. & Noguchi, T., 2002, In : Pathophysiology. 8, 3, p. 167-174 8 p.

Research output: Contribution to journalArticle

Reperfusion
Free Radicals
Ischemia
Liver
Tetradecanoylphorbol Acetate
6 Citations (Scopus)

Free radicals and oxidative stress: Targeted ESR measurement of free radicals

Egashira, T. & Takayama, F., 2002, In : Folia Pharmacologica Japonica. 120, 4, p. 229-236 8 p.

Research output: Contribution to journalArticle

Electron Spin Resonance Spectroscopy
Free Radicals
Oxidative Stress
Spin Trapping
Reactive Oxygen Species
2001
63 Citations (Scopus)

Effect of endotoxin-induced reactive oxygen species on sperm motility

Urata, K., Narahara, H., Tanaka, Y., Egashira, T., Takayama, F. & Miyakawa, I., 2001, In : Fertility and Sterility. 76, 1, p. 163-166 4 p.

Research output: Contribution to journalArticle

Sperm Motility
Endotoxins
Reactive Oxygen Species
Lipopolysaccharides
Spermatozoa
13 Citations (Scopus)

Protective effect of Ninjin-yoei-to on damage to isolated hepatocytes following transient exposure to tert-butyl hydroperoxide

Takayama, F., Egashira, T. & Yamanaka, Y., 2001, In : Japanese Journal of Pharmacology. 85, 3, p. 227-233 7 p.

Research output: Contribution to journalArticle

tert-Butylhydroperoxide
Culture Media
Ketoglutaric Acids
Hepatocytes
Acid Phosphatase
11 Citations (Scopus)

Singlet oxygen generation from phosphatidylcholine hydroperoxide in the presence of copper

Takayama, F., Egashira, T. & Yamanaka, Y., Mar 2 2001, In : Life Sciences. 68, 15, p. 1807-1815 9 p.

Research output: Contribution to journalArticle

Singlet Oxygen
Copper
Piperidones
Electron Spin Resonance Spectroscopy
Paramagnetic resonance
2000
53 Citations (Scopus)

Antioxidant and hepatoprotective actions of the medicinal herb artemisia campestris from the Okinawa Islands

Aniya, Y., Shimabukuro, M., Shimoji, M., Kohatsu, M., Gyamfi, M. A., Miyagi, C., Kunii, D., Takayama, F. & Egashira, T., Mar 2000, In : Biological and Pharmaceutical Bulletin. 23, 3, p. 309-312 4 p.

Research output: Contribution to journalArticle

Artemisia
Medicinal Plants
Islands
Antioxidants
Superoxides
3 Citations (Scopus)

Day/night variation of 5-hydroxyindole acetic acid concentration in rat cerebrospinal fluid after acute and long-term administration of a selective serotonin reuptake inhibitor, fluvoxamine

Egashira, T., Takayama, F., Yamanaka, Y., Takada, K., Takeda, H. & Matsumiya, T., 2000, In : Japanese Journal of Pharmacology. 83, 4, p. 344-347 4 p.

Research output: Contribution to journalArticle

Fluvoxamine
Serotonin Uptake Inhibitors
Acetic Acid
Cerebrospinal Fluid
Light
2 Citations (Scopus)
Glycyrrhetinic Acid
Glycyrrhizic Acid
tert-Butylhydroperoxide
Hepatocytes
Culture Media
4 Citations (Scopus)

Styrene inhibits monoamine oxidase A, but not monoamine oxidase B in monkey brain mitochondria

Egashira, T., Takayama, F., Sakai, K. & Yamanaka, Y., Sep 30 2000, In : Toxicology Letters. 117, 1-2, p. 115-119 5 p.

Research output: Contribution to journalArticle

Mitochondria
Styrene
Monoamine Oxidase
Haplorhini
Brain
1999
5 Citations (Scopus)
Trazodone
Serotonin Uptake Inhibitors
Cerebrospinal Fluid
Light
Acetic Acid

Effect of glycyrrhizin on monoamine dynamics in the rat brain

Egashira, T., Takayama, F., Yamanaka, Y., Takada, K., Takeda, H. & Matsumiya, T., 1999, In : Japanese Pharmacology and Therapeutics. 27, 4, p. 171-175 5 p.

Research output: Contribution to journalArticle

Glycyrrhizic Acid
Brain
Hippocampus
Dopamine
Norepinephrine
6 Citations (Scopus)

ESR measurement of endogenous nitric oxide in liver and blood of mice subjected to hepatic ischemia-reperfusion

Takayama, F., Egashira, T. & Yamanaka, Y., Apr 1999, In : Pathophysiology. 6, 1, p. 45-51 7 p.

Research output: Contribution to journalArticle

Electron Spin Resonance Spectroscopy
Reperfusion
Nitric Oxide
Ischemia
Liver
13 Citations (Scopus)

Monitoring of radical scavenging activity of peroral administration of the Kampo medicine Sho-saiko-to in rats

Egashira, T., Takayama, F., Yamanaka, Y. & Komatsu, Y., 1999, In : Japanese Journal of Pharmacology. 80, 4, p. 379-382 4 p.

Research output: Contribution to journalArticle

Kampo Medicine
Superoxides
Hydroxyl Radical
Theophylline
Reaction Time

NO contribution to lipopolysaccaride-induced hepatic damage in galactosamine-sensitized mice.

Takayama, F., 1999, In : J. Tox. Sci.. 24, p. 69-75 7 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

No contribution to lipopolysaccharide-induced hepatic damage in galactosamine-sensitized mice

Takayama, F., Egashira, T. & Yamanaka, Y., Feb 1999, In : Journal of Toxicological Sciences. 24, 1, p. 69-75 7 p.

Research output: Contribution to journalArticle

Galactosamine
Lipopolysaccharides
Nitric Oxide
Liver
Ketoglutaric Acids
25 Citations (Scopus)

The inhibition of monoamine oxidase activity by various antidepressants: Differences found in various mammalian species

Egashira, T., Takayama, F. & Yamanaka, Y., 1999, In : Japanese Journal of Pharmacology. 81, 1, p. 115-121 7 p.

Research output: Contribution to journalArticle

Monoamine Oxidase
Antidepressive Agents
Brain
Haplorhini
Dogs

グリチルリチンの脳内モノアミン動態に及ぼす影響.

Takayama, F., 1999, In : 薬理と治療. 27, p. 671-675 5 p.

Research output: Contribution to journalArticle